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5851 - 5900 of 8862 citations for 6 1 4 dioxa 8 azaspiro 4.5 decan 8 yl 3 hydroxy 2 iminopyrimidin 4 amine since 2019

• A novel SATB1 protein isoform with different biophysical properties

  Tomas Zelenka, et al., bioRxiv - Molecular Biology 2023

  Quote: ... The membrane was blotted using SATB1 antibodies (custom-made anti-long in a 1:200 dilution and Santa Cruz sc-376097 in a 1:200 dilution) or anti-GFP (Minotech Biotechnology ...
• MYBPHL nonsense mutations have poor sarcomere binding, are degraded, and cause abnormal contraction

  Alejandro Alvarez-Arce, et al., bioRxiv - Physiology 2024

  Quote: ... Primary antibodies against MyBP-HL (Barefield, 2022; 1:2500, (Barefield et al., 2022)) and cMyBP-C (Santa Cruz Tech, E7; Cat. No: sc-137180; 1:2500) were incubated in blocking buffer overnight at 4 °C ...
• SARS-CoV-2 infection induces a pro-inflammatory cytokine response through cGAS-STING and NF-κB

  Christopher J. Neufeldt, et al., bioRxiv - Microbiology 2020

  Quote: ... Mouse anti-P65/RELA (Santa Cruz: sc-8008, IF – 1:100); Rabbit anticGAS (Atlas Antibodies ...
• Constitutive activation of the PI3K-Akt-mTORC1 pathway sustains the m.3243A>G mtDNA mutation

  Chih-Yao Chung, et al., bioRxiv - Cell Biology 2021

  Quote: ... and anti-β-actin (1:10000, Santa Cruz Biotechnology #sc-47778).
• Combined oncolytic adenovirus carrying MnSOD and mK5 genes both regulated by survivin promoter has synergistic inhibitory effect on gastric cancer

  Shanshan Liu, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Cleaved-PARP (1:10000) (purchased from Santa Cruz Biotechnology. CA. USA), Caspase-8 (1:1000) ...
• EIPR1 controls dense-core vesicle cargo retention and EARP complex localization in insulin-secreting cells

  Irini Topalidou, et al., bioRxiv - Cell Biology 2019

  Quote: ... mouse monoclonal anti-c-Myc (1:1000, Santa Cruz, sc-40), mouse monoclonal anti-beta-tubulin (1:1000 ...
• Bbs5 functions as the docking compartment of Bbsome binding to Klc3 regulated by Bbs5-Ser²⁴⁶ PKC-phosphorylation during mouse spermatogenesis

  Dahai Yu, et al., bioRxiv - Cell Biology 2020

  Quote: ... and immunoblotted with antibodies to Bbs5 (1:200; Santa Cruz Biotechnology), phospho-Bbs5-pSer19 /nonphospho-Bbs5-Ser19 ...
• Local RNA translation controls cell migration and Rab GTPase function

  Konstadinos Moissoglu, et al., bioRxiv - Cell Biology 2020

  Quote: ... and anti-RABIF (1:1,500; Santa Cruz biotechnology, cat# sc-390759). After washing ...
• C-Jun N-terminal kinase (JNK) pathway activation is essential for dental papilla cells polarization

  Jiao Luo, Xiujun Tan, Ling Ye, Chenglin Wang, bioRxiv - Cell Biology 2020

  Quote: ... anti-rabbit IgG FITC conjugated (1:200, Santa Cruz, CA, USA). Cells at the leading edge of scratch line were observed ...
• Endogenous formaldehyde scavenges cellular glutathione resulting in cytotoxic redox disruption

  Carla Umansky, et al., bioRxiv - Cell Biology 2020

  Quote: ... 1 mM Glutathione monoethyl ester (GSH-MEE, Santa Cruz, # sc-203974); 0 and 1 mM Trolox (Sigma-Aldrich ...
• TRIP6 is required for tension at adherens junctions

  Srividya Venkatramanan, et al., bioRxiv - Cell Biology 2020

  Quote: ... and mouse anti-TRIP6 (1:100; Santa Cruz Biotechnology sc-365122). F-actin was stained with Alexa Fluor 647-conjugated phalloidin (1:50 ...
• Drosophila USP22/non-stop regulates the Hippo pathway to polarise the actin cytoskeleton during collective border cell migration

  Hammed Badmos, et al., bioRxiv - Cell Biology 2020

  Quote: ... Mouse anti-aPKC ζ (sc-17781, 1:200) from Santa Cruz. Guinea pig anti-Merlin (1:7500 ...
• Capturing limbal epithelial stem cell population dynamics, signature, and their niche

  Anna Altshuler, et al., bioRxiv - Cell Biology 2020

  Quote: ... Cd63 (Santa cruz sc-5275, IF-P/IF-Wmt 1:100), Ifitm3 (Abcam ab15592 ...
• Reconstitution of Alveolar Regeneration via novel DATPs by Inflammatory Niches

  Jinwook Choi, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-Hopx (1:100, Santa Cruz Biotechnology Inc., sc-30216), rabbit anti-Aqp5 (1:200 ...
• Microtubule poleward flux in human cells is driven by the coordinated action of four kinesins

  Yulia Steblyanko, et al., bioRxiv - Cell Biology 2020

  Quote: ... mouse anti-NuMA (F-11) (1:250; Santa Cruz, sc-365532), rabbit anti-HSET (1:500 ...
• Cytoprotection by a naturally occurring variant of ATP5G1 in Arctic ground squirrels

  Neel S. Singhal, et al., bioRxiv - Cell Biology 2020

  Quote: ... HSP90 (sc-69703, 1:1000, Santa Cruz Biotechnology, Dallas, TX, USA).
• Phospho-regulation of the Shugoshin - Condensin interaction at the centromere in budding yeast

  Galal Yahya Metwaly, et al., bioRxiv - Cell Biology 2019

  Quote: ... and mouse anti-HA (Y-11, Santa Cruz Biotechnology, 1:2,500) primary antibodies.
• Akt/Foxo pathway activation switches apoptosis to senescence in short telomere zebrafish

  Mounir El-Maï, et al., bioRxiv - Cell Biology 2020

  Quote: ... anti-p16 (F-12) (1:700, Santa Cruz Biotechnology, sc-1661); anti-SOD-2 (1:1000 ...
• SEMA3F-deficient colorectal cancer cells Promote lymphangiogenesis: fatty acid metabolism replace glycolysis for energy supply during lymphatic endothelial cells proliferation in tumor hypoxia microenvironment

  Xiaoyuan Fu, et al., bioRxiv - Cell Biology 2019

  Quote: ... including FITC-conjugated goat anti-rabbit IgG (1:50, Santa Cruz), FITC-conjugated goat anti-mouse IgG (1:50 ...
• Primary mammary organoid model of lactation and involution

  Jakub Sumbal, et al., bioRxiv - Cell Biology 2019

  Quote: ... mouse monoclonal anti-α-tubulin (Santa Cruz, sc-5286, 1:1000), and anti-mouse secondary antibody (Merck ...
• Identification and characterization of distinct murine brown adipocyte lineages

  Ruth Karlina, et al., bioRxiv - Cell Biology 2020

  Quote: ... β-actin (HRP-linked, Santa Cruz Biotechnology cat# sc-47778, 1:5000) was used as loading control ...
• BNIP3 phosphorylation by JNK1/2 promotes mitophagy via enhancing its stability under hypoxia

  Yun-Ling He, et al., bioRxiv - Cell Biology 2020

  Quote: ... anti-c-Myc (1:1,000, rabbit pAb, Santa Cruz, sc-789), anti-GFP (1:1,000 ...
• Genetic Disruption of WASHC4 Drives Endo-lysosomal Dysfunction and Cognitive-Movement Impairments in Mice and Humans

  Jamie L. Courtland, et al., bioRxiv - Cell Biology 2020

  Quote: Primary antibodies: Rabbit anti-Strumpellin (Santa Cruz #sc-87442, 1:500), Rabbit anti-WASH1 c-terminal (Sigma #SAB4200373 ...
• Single cell transcriptomic analyses reveal the impact of bHLH factors ATOH7 and Neurog2 on human retinal organoid development

  Xiangmei Zhang, et al., bioRxiv - Developmental Biology 2020

  Quote: ... goat anti-pan BRN3 (1:50; Santa Cruz Biotechnology, sc-6026); mouse anti-Iselt1 (1:10 ...
• Sex hormones underlying 17a-Estradiol effects on neuroinflammation

  Lucas K. Debarba, et al., bioRxiv - Neuroscience 2020

  Quote: ... For rabbit anti ER alpha (1:1000; Santa Cruz Biotechnology, CA) and rabbit anti pS6 (1:100 Cell signaling ...
• The histone modification reader ZCWPW1 links histone methylation to PRDM9-induced double strand break repair

  Tao Huang, et al., bioRxiv - Developmental Biology 2020

  Quote: ... rabbit anti-DMC1 (1:100 dilution; Santa Cruz Biotechnology #sc-22768), mouse anti-γH2AX (1:300 dilution ...
• The cell-cell adhesion protein JAM3 determines nuclear deformability by regulating microtubule organization

  Mar Arias-Garcia, et al., bioRxiv - Cell Biology 2020

  Quote: ... For the anti-goat Lamin B Antibody (Santa Cruz, 1:500) a single immunostaining was performed with a donkey anti-goat secondary antibody and Alexa-568 phalloidin ...
• LRRK2 causes centrosomal deficits via phosphorylated Rab10 and RILPL1 at centriolar subdistal appendages

  Antonio Jesús Lara Ordóñez, et al., bioRxiv - Neuroscience 2021

  Quote: ... and mouse monoclonal anti-GAPDH (Santa Cruz, sc-32233, 1:2000). Sheep polyclonal antibodies against Rab12 ...
• Tumour Suppressor Parafibromin/Hyrax Governs Cell Polarity and Centrosome Assembly in Neural Stem Cells

  Qiannan Deng, et al., bioRxiv - Developmental Biology 2021

  Quote: ... rabbit anti-aPKCζ C20 (1:100; Santa Cruz Biotechnologies, Dallas, TX), guinea-pig anti-Numb (1:1000 ...
• Acquisition of cellular properties during alveolar formation requires differential activity and distribution of mitochondria

  Kuan Zhang, et al., bioRxiv - Developmental Biology 2021

  Quote: ... mouse anti-HOPX (1:100, Santa Cruz Biotechnology, Cat# sc-398703). The primary antibodies used for frozen sections were ...
• The laminin-keratin link shields the nucleus from mechanical deformation and signalling

  Zanetta Kechagia, et al., bioRxiv - Cell Biology 2022

  Quote: ... mouse anti-GAPDH (6C5) 1:3000 (Santa Cruz, Cat# sc-32233), mouse Anti-Nesprin3 antibody [Nsp3] 1:500 (Abcam ...
• GCNA is a histone binding protein required for spermatogonial stem cell maintenance

  Jonathan Ribeiro, Gerry P. Crossan, bioRxiv - Physiology 2022

  Quote: ... anti-PLZF (1:100, catalog no. sc-28319, Santa Cruz Biotechnology); anti-WT1 (1:1000 ...
• GCNA is a histone binding protein required for spermatogonial stem cell maintenance

  Jonathan Ribeiro, Gerry P. Crossan, bioRxiv - Physiology 2022

  Quote: ... anti-PLZF (1:300, catalog no. sc-22839, Santa Cruz Biotechnology), anti-γH2AX (1:200 ...
• Plant autophagosomes mature into amphisomes prior to their delivery to the central vacuole

  Jierui Zhao, et al., bioRxiv - Plant Biology 2022

  Quote: ... 1 μM concanamycin A (conA) (CAS 80890-47-7; Santa Cruz); 50 μM 2,4-dinitrophenol (DNP ...
• A PCNA-K164R mutation impinges on origin activation and mitotic DNA synthesis

  Wendy Leung, et al., bioRxiv - Molecular Biology 2022

  Quote: ... rabbit anti-p21 (Santa Cruz, sc-397 clone C19; 1:1000), rabbit anti-FANCD2 (Abcam ...
• Genetic instability from a single S-phase after whole genome duplication

  Simon Gemble, et al., bioRxiv - Cell Biology 2022

  Quote: ... mouse anti-H2B (1/1000; sc-515808 from Santa Cruz Biotechnology), mouse anti-ORC1 (1/100 ...
• Genetic instability from a single S-phase after whole genome duplication

  Simon Gemble, et al., bioRxiv - Cell Biology 2022

  Quote: ... mouse anti-ORC1 (1/100; sc-398734 from Santa Cruz Biotechnology), mouse anti-MCM2 (1/500 ...
• Genetic instability from a single S-phase after whole genome duplication

  Simon Gemble, et al., bioRxiv - Cell Biology 2022

  Quote: ... mouse anti-CDC6 (1/500; sc-9964 from Santa Cruz, RRID:AB_627236), rabbit anti-CDT1 (1/500 ...
• Absence of postsynaptic activity on developing neurons alters gene expression profiles without preventing the refinement of inputs

  Yumaine Chong, Ellis Cooper, bioRxiv - Neuroscience 2022

  Quote: ... goat anti-MAP-1A (1:360; Santa Cruz Biotechnology, Dallas, TX)] ...
• Emerin self-assembly and nucleoskeletal coupling regulate nuclear envelope mechanics against stress

  Anthony Fernandez, et al., bioRxiv - Cell Biology 2022

  Quote: ... mouse anti-histone H2A (1:1000, Santa Cruz Biotechnology, sc-515808) and mouse anti-GAPDH (1:1000 ...
• The endoplasmic reticulum membrane protein complex localizes to the mitochondrial - endoplasmic reticulum interface and its subunits modulate phospholipid biosynthesis in Trypanosoma brucei

  Advaitha Iyer, et al., bioRxiv - Biochemistry 2022

  Quote: ... mouse monoclonal anti-cMyc (9E10, Santa Cruz Biotechnology; dilution 1:200), mouse anti-HA (16B12 ...
• A neuron, microglia, and astrocyte triple coculture model to study Alzheimer disease

  Celia Luchena, et al., bioRxiv - Neuroscience 2021

  Quote: ... Arginase I (1:200, sc-166920, Santa Cruz Biotechnology, CA, USA), Iba1 (1:500 ...
• Long-term Pannexin 1 ablation promotes structural and functional modifications in hippocampal neurons through the regulation of actin cytoskeleton and Rho GTPases activity

  Carolina Flores-Muñoz, et al., bioRxiv - Neuroscience 2021

  Quote: ... and GAPDH (mouse anti-GAPDH, sc-47724, Santa Cruz; 1:1000). After primary antibody incubation and washing incubation with a secondary anti-mouse HRP antibody (1:5000) ...
• The Cdc14 phosphatase controls resolution of recombination intermediates and crossover formation during meiosis

  Paula Alonso-Ramos, et al., bioRxiv - Genetics 2021

  Quote: ... goat polyclonal anti-Cdc14 (yE-17; 1:1000; Santa Cruz Biotechnology), goat polyclonal anti-Cdc5 (1:1000 ...
• BARD1 links histone H2A Lysine-15 ubiquitination to initiation of BRCA1-dependent homologous recombination

  Jordan R. Becker, et al., bioRxiv - Molecular Biology 2020

  Quote: ... mouse anti-BRCA1 D-9 (1:400, sc-6954 Santa Cruz), rabbit anti-BARD1 (1:500 ...
• Nucleolar stress controls mutant Huntingtin toxicity and monitors Huntington’s disease progression

  Aynur Sönmez, et al., bioRxiv - Neuroscience 2021

  Quote: ... and anti-beta actin (sc-47778, Santa Cruz Biotechnology, 1:1000). The secondary antibody was anti-mouse HRP (horseradish peroxidase)-linked (NA931 ...
• SWI/SNF chromatin remodeler complex within the reward pathway is required for behavioral adaptations to stress

  Abdallah Zayed, et al., bioRxiv - Neuroscience 2021

  Quote: ... an anti-BRG1 (mouse monoclonal, 1:1000, Santa Cruz, sc-17796) and an anti-BRM (rabbit polyclonal 1:500 ...
• Curcumin promotes progression of AApoAII amyloidosis and peroxisome proliferation in mice by activating the PPARα signaling pathway

  Jian Dai, et al., bioRxiv - Molecular Biology 2020

  Quote: ... or ApoE antibody (1:500, Santa Cruz, San Francisco, CA, USA). Next ...
• In vivo discovery of RNA proximal proteins in human cells via proximity-dependent biotinylation

  Xianzhi Lin, et al., bioRxiv - Molecular Biology 2020

  Quote: ... or anti-β-actin (Santa Cruz, Cat.# sc-47778, 1:2,000) at 4°C overnight ...
• Replication protein A binds RNA and promotes R-loop formation

  Olga M. Mazina, et al., bioRxiv - Molecular Biology 2020

  Quote: ... Then 40 µl (Santa Cruz Biotech, 25% slurry in 1 × PBS) of protein A/G plus agarose beads were added and incubation continued for another 2 h ...