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5951 - 6000 of 8862 citations for 6 1 4 dioxa 8 azaspiro 4.5 decan 8 yl 3 hydroxy 2 iminopyrimidin 4 amine since 2019

• Partial inhibition of mitochondrial complex I attenuates neurodegeneration and restores energy homeostasis and synaptic function in a symptomatic Alzheimer’s mouse model

  Andrea Stojakovic, et al., bioRxiv - Neuroscience 2020

  Quote: ... BDNF (1:200, Santa Cruz Biotechnology, Santa Cruz, CA, cat. # 546), PSD95 (1:1000 ...
• The role of sigma-1 receptor in organization of endoplasmic reticulum signaling microdomains

  Vladimir Zhemkov, et al., bioRxiv - Cell Biology 2020

  Quote: ... and anti-TOM20 antibodies (FL-145, 1:500, Santa Cruz Biotechnology) overnight at 4°C ...
• p53 drives premature neuronal differentiation in response to radiation-induced DNA damage during early neurogenesis

  André-Claude Mbouombouo Mfossa, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-γ-tubulin (goat, 1:100, Santa Cruz Biotechnology (sc-7396)) ...
• p53 drives premature neuronal differentiation in response to radiation-induced DNA damage during early neurogenesis

  André-Claude Mbouombouo Mfossa, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-β-catenin (mouse, 1:100, Santa Cruz Biotechnology (sc-7963)) ...
• Single-dose ethanol intoxication causes acute and lasting neuronal changes in the brain

  Johannes Knabbe, et al., bioRxiv - Neuroscience 2020

  Quote: ... and Ankyrin G (1:200, Santa Cruz, Company ID: sc-28561)
• Shared and divergent phase separation and aggregation properties of brain-expressed ubiquilins

  Julia E. Gerson, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-A1UP for UBQLN4 (Santa Cruz, cat. #sc-136145; 1:2000), anti-Histone H3 (Cell Signaling ...
• Structural and functional elucidation of NF-κB signaling by the p75 neurotrophin receptor through recruitment of TRADD

  Ning Zhang, et al., bioRxiv - Biophysics 2021

  Quote: ... polyclonal anti-P65 NF-κB (Santa cruz, sc-372, 1:500) and polyclonal anti-cleaved caspase 3 (Cell signal ...
• DYT-TOR1A Subcellular Proteomics Reveals Selective Vulnerability of the Nuclear Proteome to Cell Stress

  Kunal Shroff, Zachary F. Caffall, Nicole Calakos, bioRxiv - Neuroscience 2021

  Quote: ... anti-Na+/K+ - ATPase (Santa Cruz Biotechnology; sc-21712; 1:500), anti-BiP (Santa Cruz Biotechnology ...
• RAD51AP1 mediates RAD51 activity through nucleosome interaction

  Elena Pires, et al., bioRxiv - Biochemistry 2021

  Quote: ... α-RAD54 (F-11; sc-374598; Santa Cruz Biotechnology; 1:500); α-RAD51 (Ab-1 ...
• Cell Surface Glycan Engineering Reveals that Matriglycan Alone can Recapitulate Dystroglycan Binding and Function

  M. Osman Sheikh, et al., bioRxiv - Biochemistry 2021

  Quote: ... The anti-core β-DG mAb 7D11 (1:1000, Santa Cruz) was detected by secondary antibody donkey anti-mouse IgG IR680RD (1:10,000 ...
• Modeling airway dysfunction in asthma using synthetic mucus biomaterials

  Daniel Song, et al., bioRxiv - Bioengineering 2020

  Quote: ... and mouse monoclonal anti-MUC5B (Santa Cruz, sc-21768, 1:100). Primary antibody incubation was over night at 4°C in 1% BSA in PBS ...
• Convergent evolution between PALI1 and JARID2 for the allosteric activation of PRC2

  Qi Zhang, et al., bioRxiv - Biochemistry 2020

  Quote: ... anti-rabbit HRP-conjugated (Santa Cruz Biotechnology #sc-2357, 1:5000).
• beta-blocker reverses inhibition of beta-2 adrenergic receptor resensitization by hypoxia

  Yu Sun, et al., bioRxiv - Biochemistry 2020

  Quote: ... Anti-phospho-β2AR 355/356 [40] antibody (1:500, Santa cruz) diluted in 1% goat serum was used as primary antibody ...
• Bimolecule detection for Extracellular Vesicle Screening

  Hisako Kaneda, et al., bioRxiv - Biochemistry 2020

  Quote: ... or HRP-conjugated anti-rat IgG (Santa Cruz; 1:3000-5000) were reacted at room temperature for 1 hour ...
• Bimolecule detection for Extracellular Vesicle Screening

  Hisako Kaneda, et al., bioRxiv - Biochemistry 2020

  Quote: ... HRP-conjugated anti-goat IgG (Santa Cruz, TX; 1:3000-5000), Rabbit or Mouse TrueBlot® ...
• Human Deep Cortical Neurons Promote Regeneration and Recovery After Cervical Spinal Cord Injury

  Vanessa M. Doulames, et al., bioRxiv - Neuroscience 2021

  Quote: ... NCAM (106, 1:500 dilution; Santa Cruz Biotechnology, Inc., Dallas, TX), Neurofilament-H (NFH ...
• A functional network signature in the developing cerebellum: evidence from a preclinical model of autism

  María Berenice Soria-Ortiz, et al., bioRxiv - Neuroscience 2021

  Quote: ... or rabbit anti-Actin 1:1000 (Santa Cruz, Dallas TX, USA).
• The entorhinal cortex modulates trace fear memory formation and neuroplasticity in the lateral amygdala via cholecystokinin

  Hemin Feng, et al., bioRxiv - Neuroscience 2021

  Quote: ... sections were counter-stained with DAPI (1:10000, Santa Cruz Biotechnology) for 10 min and mounted onto slides with 70% glycerol (Santa Cruz Biotechnology ...
• Wt1 positive neurons in the hindbrain are essential for respiration

  Danny Schnerwitzki, et al., bioRxiv - Neuroscience 2019

  Quote: ... Wt1 1:100 (Santa Cruz Biotechnology, Inc., Santa Cruz, California, USA), Wt1 1:1000 (abcam ...
• Autophagy is required for midbrain dopaminergic axon development and their responsiveness to guidance cues

  M.S. Profes, A. Saghatelyan, M. Lévesque, bioRxiv - Neuroscience 2020

  Quote: ... and donkey anti-sheep HRP (1:5000; Santa Cruz, sc-2473). Membranes were covered with ECL for 1 min (Western Lightning Plus-ECL ...
• Functional diversity of PFKFB3 splice variants in glioblastomas

  Ulli Heydasch, et al., bioRxiv - Cancer Biology 2020

  Quote: ... donkey-anti-goat IgG POD (1:120000; Santa Cruz Biotechnology, Heidelberg) or goat-anti-mouse IRDye 800CW (1:15000 ...
• BMP7 increases UCP1-dependent and independent thermogenesis with a unique gene expression program in human neck area derived adipocytes

  Abhirup Shaw, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-PGC1α (1:1000, Santa Cruz Biotechnology, TX, USA, H-300), anti-CKMT2 (1:1000 ...
• PDZ and LIM domain protein 2 plays dual and context-dependent roles in breast cancer development

  Josef Maryas, et al., bioRxiv - Cancer Biology 2020

  Quote: ... mouse anti-p65 Ab (1:500) was purchased from Santa Cruz Biotechnology ...
• Membrane metalloendopeptidase suppresses prostate carcinogenesis by attenuating effects of gastrin-releasing peptide on stem/progenitor cells

  Chieh-Yang Cheng, et al., bioRxiv - Cancer Biology 2019

  Quote: ... or anti-mouse secondary antibodies (Santa Cruz, #sc-2005, 1:2000) and developed using chemiluminescent substrate (Thermo Scientific ...
• The p97-UBXD8 complex modulates ER-Mitochondria contact sites by modulating membrane lipid saturation and composition

  Rakesh Ganji, et al., bioRxiv - Cell Biology 2021

  Quote: ... and UBE2S (C-1; sc390917) antibodies were obtained from Santa Cruz Biotechnologies ...
• Extracellular vesicles as predictors of individual response to exercise training in youth living with obesity

  Taiana M. Pierdoná, et al., bioRxiv - Physiology 2020

  Quote: ... mouse monoclonal anti-CD81 (sc-166029, Santa Cruz Biotechnology, 1:200), rabbit polyclonal anti-Cytochrome C (Cyt C ...
• Extracellular vesicles as predictors of individual response to exercise training in youth living with obesity

  Taiana M. Pierdoná, et al., bioRxiv - Physiology 2020

  Quote: ... mouse monoclonal anti-MMP2 (sc-13595, Santa Cruz Biotechnology, 1:200), mouse monoclonal anti-Apolipoprotein A1 (Apo-A1 ...
• Cryo-electron microscopy structures of pyrene-labeled ADP-P_i- and ADP-actin filaments

  Steven Z. Chou, Thomas D. Pollard, bioRxiv - Biochemistry 2020

  Quote: We purchased N-(1-pyrene)iodoacetamide (sc-472510) from Santa Cruz Biotechnologies ...
• Sterilization of drug-resistant influenza virus through genetic interference: use of unnatural amino acid-engineered virions

  Xuesheng Wu, et al., bioRxiv - Bioengineering 2021

  Quote: ... Anti-GAPDH protein antibodies (1:1000, sc-365062, Santa Cruz Biotechnology), anti-GFP antibodies (1:1000 ...
• Transendothelial migration induces differential migration dynamics of leukocytes in tissue matrix

  Abraham C.I. van Steen, et al., bioRxiv - Cell Biology 2021

  Quote: ... Mouse anti-hICAM-1 AF546 conjugated (15.2, Santa Cruz, #sc-107AF546), anti-Collagen IV (Abcam ...
• RAD51AP1 and RAD54 underpin two distinct RAD51-dependent routes of DNA damage repair via homologous recombination

  Platon Selemenakis, et al., bioRxiv - Cell Biology 2021

  Quote: ... α-RAD54 (F-11; sc-374598; Santa Cruz Biotechnology; 1:1,000); α-RAD51 (Ab-1 ...
• LAMP2A regulates the loading of proteins into exosomes

  João Vasco Ferreira, et al., bioRxiv - Cell Biology 2021

  Quote: ... mouse Lamin B1 dilution 1:500 (Santa Cruz Biotechnology, sc-374015); goat anti-Calnexin dilution 1:1000 (Sicgen ...
• Human IFITM3 restricts Chikungunya virus and Mayaro virus infection and is susceptible to virus-mediated counteraction

  Sergej Franz, et al., bioRxiv - Microbiology 2020

  Quote: ... mouse anti-ISG15 (clone F-9, Santa Cruz Technologies, 1:500), mouse anti-IFITM1 (clone 5B5E2 ...
• REST/NRSF drives homeostatic plasticity of inhibitory synapses in a target-dependent fashion

  Cosimo Prestigio, et al., bioRxiv - Neuroscience 2021

  Quote: ... anti-GAPDH (1:2000; sc-25778 Santa Cruz Biotechnology, Dallas, TX). After several washes ...
• Dissociable control of unconditioned responses and associative fear learning by parabrachial CGRP neurons

  Anna J. Bowen, et al., bioRxiv - Neuroscience 2020

  Quote: ... goat anti-c-Fos (1:500, Santa Cruz Biotechnology, sc-52), chicken-anti-GFP (1:10000 ...
• IPSC-derived midbrain astrocytes from Parkinson’s disease patients carrying pathogenic SNCA mutations exhibit alpha-synuclein aggregation, mitochondrial fragmentation and excess calcium release

  Peter A. Barbuti, et al., bioRxiv - Neuroscience 2020

  Quote: ... The mouse anti-Tom20 antibody (1:1000; Santa Cruz, sc-17764) was used with the Alexa Fluor 488 (Life Technologies ...
• Mutations in TMEM43 cause autosomal dominant auditory neuropathy spectrum disorder via interaction with connexin-mediated passive conductance channels

  Minwoo Wendy Jang, et al., bioRxiv - Genetics 2020

  Quote: ... K+-ATPase-α3 polyclonal (NKA, 1:250, SC-16052, Santa Cruz), and mouse anti-CtBP2 monoclonal (1:500 ...
• Analysis of the PcrA-RNA polymerase complex reveals a helicase interaction motif and a role for PcrA/UvrD helicase in the suppression of R-loops

  I. Urrutia-Irazabal, et al., bioRxiv - Biochemistry 2021

  Quote: ... An anti-mouse HRP antibody (1:10000 dilution, Santa Cruz Biotechnology) was used as secondary antibody ...
• Coordinated assembly and release of adhesions builds apical junctional belts during de novo polarisation of an epithelial tube

  Andrew C Symonds, et al., bioRxiv - Neuroscience 2020

  Quote: ... rabbit anti-aPKC (rabbit polyclonal, Santa Cruz sc-216, 1:300), mouse anti-©tubulin (mouse monoclonal ...
• MRI of Capn15 knockout mice and analysis of Capn 15 distribution reveal possible roles in brain development and plasticity

  Congyao Zha, et al., bioRxiv - Neuroscience 2021

  Quote: ... goat polyclonal antibody directed against Brn3a (Santa Cruz, dilution 1:500), goat polyclonal antibody directed against ChAT (Millipore Sigma ...
• ERBB2 is a Key Mediator in Hearing Restoration in Noise-Deafened Young Adult Mice

  Jingyuan Zhang, et al., bioRxiv - Neuroscience 2021

  Quote: ... and goat anti-Oncomodulin (OCM) antibody (1:1000; Santa Cruz; RRID:AB_2267583). The following secondary antibodies ...
• Isoprenylcysteine carboxylmethyltransferase-based therapy for Hutchinson–Gilford progeria syndrome

  Beatriz Marcos-Ramiro, et al., bioRxiv - Pharmacology and Toxicology 2020

  Quote: ... anti-lamin A/C (Santa Cruz Biotechnology, sc-376248, 1:500) and anti-GAPDH (Cell Signaling ...
• The globular C1q receptor is required for epidermal growth factor receptor signaling during Candida albicans infection

  Quynh T. Phan, et al., bioRxiv - Microbiology 2021

  Quote: ... mouse anti-EGFR (Santa Cruz Biotechnology # SC-101, clone R-1), anti-WBP2 (Santa Cruz Biotechnology ...
• An infection-activated redox switch promotes tumor growth

  Yekaterina Kovalyova, et al., bioRxiv - Microbiology 2021

  Quote: ... mouse monoclonal anti-LAMP1 (Santa Cruz sc-20011; 1:500 dilution), rabbit polyclonal anti-S6K1 (Cell Signaling 9202 ...
• A fluorescence-based genetic screen reveals diverse mechanisms silencing small RNA signaling in E. coli

  Jiandong Chen, et al., bioRxiv - Microbiology 2021

  Quote: ... and anti-mouse AP-conjugated IgG (1:10,000; Santa Cruz Biotechnology).
• Divide et Impera: Identification of Small-Molecule Inhibitors of HCMV Replication Interfering with Dimerization of DNA Polymerase Processivity Factor UL44

  Hanieh Ghassabian, et al., bioRxiv - Microbiology 2020

  Quote: ... rabbit α-GADPH pAb (Santa Cruz Biotech, #sc-25778; 1:5,000); mouse α-β-Actin mAb (Sigma Aldrich ...
• Small extracellular vesicles from iPSC-MSC lose their regenerative potential upon UV-C irradiation

  M.C. Biani, et al., bioRxiv - Cell Biology 2021

  Quote: ... and goat anti-human GAPDH (1:1000, #SC-20357, Santa Cruz). The membranes were washed with PBS-0.1% Tween three times and incubated with HRP-conjugated secondary antibodies (1:5000 ...
• Cofilin Regulates Filopodial Structure and Flexibility in Neuronal Growth Cones

  Ryan Hylton, et al., bioRxiv - Cell Biology 2021

  Quote: ... mouse anti-fascin at a 1:500 dilution (Santa Cruz Biotechnology). Secondary antibodies (also diluted in blocking buffer from above ...
• Scleraxis-Lineage Cell Depletion Improves Tendon Healing and Disrupts Adult Tendon Homeostasis

  Katherine T. Best, et al., bioRxiv - Cell Biology 2020

  Quote: ... F4/80 (1:500, Cat#: sc-26643, Santa Cruz, Dallas, TX), α-SMA-CY3 (1:200 ...
• Modified N-linked glycosylation status predicts trafficking defective human Piezo1 channel mutations

  Jinyuan Vero Li, et al., bioRxiv - Biophysics 2020

  Quote: ... mouse anti-α-actinin antibody (Santa Cruz Biotechnology; 1:5,000 dilution) or anti-α-tubulin (Clone DM1A ...