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5701 - 5750 of 8862 citations for 6 1 4 dioxa 8 azaspiro 4.5 decan 8 yl 3 hydroxy 2 iminopyrimidin 4 amine since 2019

• Nuclear damage in LMNA mutant iPSC-derived cardiomyocytes is associated with impaired lamin localization to the nuclear envelope

  Melanie Wallace, et al., bioRxiv - Cell Biology 2023

  Quote: ... The Lamin A/C antibody used (Santa Cruz; E-1) targeted the N-terminus (AA 2-29 ...
• Evidence of target-mediated miRNA degradation in Drosophila ovarian cell culture

  Natalia Akulenko, et al., bioRxiv - Molecular Biology 2023

  Quote: ... or goat anti-CyclinA (1:100, Santa Cruz, N-15). Then ...
• 3D human retinal organoid model for the study of early diabetic retinopathy

  Luisa de Lemos, et al., bioRxiv - Neuroscience 2023

  Quote: ... goat anti-BRN3a (1:100, sc-31989, Santa Cruz Biotechnology), goat anti-OTX2 (1:100 ...
• A CRISPR screen of HIV dependency factors reveals CCNT1 is non-essential in T cells but required for HIV-1 reactivation from latency

  Terry L Hafer, et al., bioRxiv - Microbiology 2023

  Quote: ... mouse α-CCNT2 (Santa Cruz Biotechnology, sc-81243, 1:500), and rabbit α-actin (Sigma-Aldrich ...
• Development of Gemcitabine-Modified miRNA Mimics as Cancer Therapeutics for Pancreatic Ductal Adenocarcinoma

  John G. Yuen, et al., bioRxiv - Cancer Biology 2023

  Quote: ... or mouse anti-GAPDH antibody (Santa Cruz, sc47724, 1:100,000). Primary antibodies were diluted in 5% milk (Bio-Rad ...
• The differentiation and integration of the hippocampal dorsoventral axis are controlled by two nuclear receptor genes

  Xiong Yang, et al., bioRxiv - Developmental Biology 2023

  Quote: ... goat anti-NeuroD1 (1:200, Santa Cruz, Cat # sc-1084), goat anti-Lhx2 (1:200 ...
• C4 induces pathological synaptic loss by impairing AMPAR trafficking

  Rhushikesh A. Phadke, et al., bioRxiv - Neuroscience 2023

  Quote: ... Mouse anti-GAPDH (1:1000, Santa Cruz Biotechnology, sc-47724), Mouse anti-FLAG (1:1000 ...
• Capsicum chinense Jacq. derived glutaredoxin (CcGRXS12) alters phytohormonal pathways and redox status of the cells to confer resistance against pepper mild mottle virus (PMMoV-I)

  R. M. Saravana Kumar, et al., bioRxiv - Biochemistry 2023

  Quote: ... GFP specific polyclonal antibody (1/250; Santa Cruz Biotechnology, INC.) and PMMoV-I CP (1/1000 ...
• Tetherin antagonism by SARS-CoV-2 enhances virus release: multiple mechanisms including ORF3a-mediated defective retrograde traffic

  Hazel Stewart, et al., bioRxiv - Cell Biology 2022

  Quote: ... mouse anti-VPS35 (Santa Cruz, B-5, IF 1:300), mouse anti-CD63 (BioLegend ...
• Cystin is required for maintaining fibrocystin (FPC) levels and safeguarding proteome integrity in mouse renal epithelial cells A mechanistic connection between the kidney defects in cpk mice and human ARPKD

  Yiming Zhang, et al., bioRxiv - Cell Biology 2023

  Quote: ... β-actin (mouse, mAb, Santa Cruz; sc-47778; 1:3000), Ift88 (rabbit pAb ...
• Panton-Valentine leukocidin-induced neutrophil extracellular traps lack antimicrobial activity and are readily induced in patients with recurrent PVL⁺-Staphylococcus aureus infections

  Hina Jhelum, et al., bioRxiv - Immunology 2022

  Quote: ... 10 µg/ml CD88 (S5/1)-FITC (Santa Cruz Biotechnology) and 10 µg/ml anti-human C5L2-APC (BioLegend ...
• Autophagy mediates cancer cell resistance to doxorubicin induced by the Programmed Death 1/Programmed Death Ligand 1 immune checkpoint axis

  Lori Minassian, et al., bioRxiv - Cancer Biology 2023

  Quote: ... rabbit anti-α-actinin (Santa Cruz sc-15335, 1:1000), or mouse anti-β-actin (Sigma Aldrich A5441 ...
• Human papillomavirus 16 E2 interaction with TopBP1 is required for E2 and viral genome stability during the viral life cycle

  Apurva T. Prabhakar, et al., bioRxiv - Cancer Biology 2023

  Quote: ... HPV16 E7 1:200 (Santa Cruz, catalog no. sc-6981), E2 tag [5E11] 1:1000 (Abcam ...
• Modelling drug responses and evolutionary dynamics using triple negative breast cancer patient-derived xenografts

  Abigail Shea, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and probed using BRCA1 (Santa Cruz, sc-6954, 1:200) and β-tubulin (Cell Signaling Technology ...
• CRISPR/Cas9-mediated knockout of the ubiquitin variant Ub^KEKS reveals a role in regulating nucleolar structures and composition

  Julie Frion, et al., bioRxiv - Cell Biology 2023

  Quote: ... UBF (F-9, sc-13125, Santa Cruz Biotechnology , 1:300) or fibrillarin (38F3 ...
• Intermediate filament dysregulation and astrocytopathy in the human disease model of KLHL16 mutation in giant axonal neuropathy (GAN)

  Rachel Battaglia, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse anti-Gigaxonin (Santa Cruz Biotechnology, F3, WB 1:200), rabbit anti-Vimentin (Cell Signaling Technology ...
• Cell division tracing combined with single-cell transcriptomics reveals new cell types and differentiation paths in the regenerating mouse lung

  Leila R. Martins, et al., bioRxiv - Cell Biology 2023

  Quote: ... Cyp2f2-Alexa Fluor 647 (1:1000, #sc-374540, Santa Cruz), GFP-FITC (1:500 ...
• A hierarchical pathway for assembly of the distal appendages that organize primary cilia

  Tomoharu Kanie, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse IgG2a anti-RAB34 (sc-365986, Santa Cruz, 1:250), and mouse IgG2b anti-FOP (H00011116-M01 ...
• A hierarchical pathway for assembly of the distal appendages that organize primary cilia

  Tomoharu Kanie, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse IgG2a anti-MYO5A (sc-365986, Santa Cruz, 1:1000), and mouse IgG2b anti-FOP (H00011116-M01 ...
• EHD1-dependent traffic of IGF-1 receptor to the cell surface is essential for Ewing sarcoma tumorigenesis and metastasis

  Sukanya Chakraborty, et al., bioRxiv - Cancer Biology 2023

  Quote: ... IGF-1 Receptor α mAb(1H7) (Santa Cruz; #sc-461); doxycycline (Sigma Aldrich ...
• Arginine shortage induces replication stress and confers genotoxic resistance by inhibiting histone H4 translation and promoting PCNA polyubiquitination

  Yi-Chang Wang, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-cyclin A (1:1000; Cat# sc-751, Santa Cruz), anti-cyclin B1 (1:1000 ...
• MARCH5-dependent NLRP3 ubiquitination is an essential step for NEK7 docking on the mitochondria

  Yeon-Ji Park, et al., bioRxiv - Immunology 2023

  Quote: ... anti-IL-1β (1:1,000, sc-12742, Santa Cruz biotechnology), anti-mouse caspase-1 (1:1,000 ...
• A Cas9-fusion proximity-based approach generates an Irak1-Mecp2 tandem duplication mouse model for the study of MeCP2 duplication syndrome

  Eleonora Maino, et al., bioRxiv - Genetics 2023

  Quote: ... rabbit monoclonal anti-GAPDH (sc-47724, Santa Cruz, 1:10000) overnight at 4C ...
• Matrix Gla Protein acts as a driver of stemness and tumor initiation in ovarian cancer

  V. Nieddu, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Lamin A/C (Santa Cruz, cat# sc-7292, 1:500), α-tubulin (Santa Cruz ...
• In vivo functional genomics identifies essentiality of potassium homeostasis in medulloblastoma

  Jerry J. Fan, et al., bioRxiv - Cancer Biology 2023

  Quote: ... mouse anti-PCNA (Santa Cruz Biotechnology #sc-56, 1:200), mouse anti-SOX2 (abcam #ab79351 ...
• Loss of EED in the oocyte causes initial fetal growth restriction followed by placental hyperplasia and offspring overgrowth

  Ruby Oberin, et al., bioRxiv - Developmental Biology 2023

  Quote: ... Mouse anti-PLAC1 (G-1) (Santa Cruz, Cat# sc-365919) primary antibody was applied at an appropriate concentration for 1 hour ...
• Tetherin antagonism by SARS-CoV-2 enhances virus release: multiple mechanisms including ORF3a-mediated defective retrograde traffic

  Hazel Stewart, et al., bioRxiv - Cell Biology 2022

  Quote: ... goat anti-EF2 (Santa Cruz, C-14, WB 1:10,000), mouse anti- tubulin (Proteintech ...
• SLC15A4 controls endolysosomal TLR7-9 responses by recruiting the innate immune adaptor TASL

  Haobo Zhang, et al., bioRxiv - Immunology 2023

  Quote: ... and mouse anti-LAMP2 (sc-18822, Santa Cruz, 1:1,000) in blocking solution ...
• A dual, catalytic role for the fission yeast Ccr4-Not complex in gene silencing and heterochromatin spreading

  Drice Challal, et al., bioRxiv - Genetics 2023

  Quote: ... and 1:5000 goat anti-mouse IgG-HRP (Santa Cruz Biotechnology ...
• mRNA Location and Translation Rate Determine Protein Targeting to Dual Destinations

  Alexander N. Gasparski, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse anti-CASK (1:1000, Santa Cruz cat# sc-13158), rabbit anti-CASK (1:1000 ...
• Arl3 regulates ODA16-mediated intraflagellar transport in motile cilia biogenesis

  Yameng Huang, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-α-tubulin (mouse, Santa cruz, sc-23948, 1:5000), anti-mCherry (rabbit ...
• IL-38 regulates intestinal stem cell homeostasis by inducing WNT signaling and beneficial IL-1β secretion

  Alberto Dinarello, et al., bioRxiv - Cell Biology 2023

  Quote: ... organoids were incubated with Lysozyme 1 (mouse, Santa Cruz Biotechnology), IL-38 (rabbit ...
• Nucleolar structure connects with global nuclear organization

  Chen Wang, et al., bioRxiv - Cell Biology 2023

  Quote: ... CENPA (Thermo Fisher #MA1-20832, 1:100; coilin, Santa Cruz Biotechnology ...
• Unveiling the role of osteosarcoma-derived secretome in premetastatic lung remodelling

  Sara F.F. Almeida, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and CD44/HCAM (1:200,sc-7297, Santa Cruz Biotechnology), overnight at 4 °C ...
• Reduction of retinal ganglion cell death in mouse models of familial dysautonomia using AAV-mediated gene therapy and splicing modulators

  Anastasia Schultz, et al., bioRxiv - Neuroscience 2023

  Quote: ... an anti-Brn3 antibody (1:200, Santa Cruz, #sc-6026), and an anti-ELP1(IKAP ...
• Transplanted Autologous Neural Stem Cells Show Promise in Restoring Motor Function in Monkey Spinal Cord Injury

  Razieh Jaberi, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-SOX2 (1:200, Santa Cruz, Sc-20088, the USA), The next day ...
• FOXM1 expression reverts aging chromatin profiles through repression of the senescence-associated pioneer factor AP-1

  Fábio J. Ferreira, et al., bioRxiv - Genetics 2023

  Quote: ... anti-p21 (F-5, sc-6246, Santa Cruz, 1:800) and anti p16INK4a (ab7962 ...
• Mitochondrial CISD1/Cisd accumulation blocks mitophagy and genetic or pharmacological inhibition rescues neurodegenerative phenotypes in Pink1/parkin models

  Aitor Martinez, et al., bioRxiv - Neuroscience 2023

  Quote: ... TOM20 (clone F-10, Santa Cruz, sc-17764, 1:1000), HA (Cell Signaling ...
• GTPBP8 is required for mitoribosomal biogenesis and mitochondrial translation

  Liang Wang, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse anti-myc (1:100, sc-40, Santa Cruz Biotechnology), rabbit anti-COXIV (1:100 ...
• GTPBP8 is required for mitoribosomal biogenesis and mitochondrial translation

  Liang Wang, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse anti-TOM20 (1:1000, sc-17764, Santa Cruz Biotechnology), rabbit anti-TOM40 (1:1000 ...
• A developmentally-inspired hypoxia condition promotes kidney organoid differentiation from human pluripotent stem cells

  Hyeonji Lim, et al., bioRxiv - Bioengineering 2023

  Quote: ... and anti-goat (1:5000) (sc-2020, Santa Cruz Biotechnology) antibodies ...
• APC/C prevents non-canonical order of cyclin/CDK activity to maintain CDK4/6 inhibitor-induced arrest

  Brandon L Mouery, et al., bioRxiv - Cell Biology 2023

  Quote: ... Geminin (1:3000; rabbit; sc-13015; Santa Cruz Biotechnology; milk), Cdt1 (1:1000 ...
• Voluntary wheel running mitigates disease in an Orai1 gain-of-function mouse model of tubular aggregate myopathy

  Thomas N. O’Connor, et al., bioRxiv - Physiology 2023

  Quote: ... rabbit anti-pan SERCA (1:10000, Santa Cruz, sc-30110), rabbit anti-Voltage-dependent anion channel (VDAC ...
• Spatial transcriptomics and single-nucleus RNA sequencing reveal a transcriptomic atlas of adult human spinal cord

  Donghang Zhang, et al., bioRxiv - Neuroscience 2023

  Quote: ... GAD67 (1:300, mouse, Santa Cruz Biotechnology, Cat#: sc-28376), CHAT (1:300 ...
• Imipridones inhibit tumor growth and improve survival in an orthotopic liver metastasis mouse model of human uveal melanoma

  Chandrani Chattopadhyay, et al., bioRxiv - Cancer Biology 2024

  Quote: ... β1-actin (RRID:AB_626632) and SDHB (RRID:AB_10659104) were from Santa Cruz Biotechnology ...
• HELZ promotes R loop resolution to facilitate DNA double-strand break repair by homologous recombination

  Ramona Haji-Seyed-Javadi, et al., bioRxiv - Molecular Biology 2023

  Quote: ... GAPDH (Santa Cruz tech # sc-47724; 1:1000 for western); 53BP1 (Bethyl # A300-273A ...
• HELZ promotes R loop resolution to facilitate DNA double-strand break repair by homologous recombination

  Ramona Haji-Seyed-Javadi, et al., bioRxiv - Molecular Biology 2023

  Quote: ... RPA32 (Santa Cruz Tech # sc-14692; 1:400 for western); pRPA32 S4/8 (Bethyl # A700-009 ...
• Dengue virus exploits the host tRNA epitranscriptome to promote viral replication

  Cheryl Chan, et al., bioRxiv - Microbiology 2023

  Quote: ... mouse anti-GAPDH (sc-47724, Santa Cruz Biotechnology, 1:10000), rabbit anti-dengue NS3 (PA532199 ...
• Predicting hypersensitivity and comorbid depressive-like behavior in late stages of joint disease using early weight bearing deficit

  Sara Hestehave, et al., bioRxiv - Neuroscience 2023

  Quote: ... or goat anti-DCX (1:500, Santa Cruz Biotechnology, F2916). Next day sections were washed three times in 0.1M PB and then incubated in darkness for 2h at RT with the respective secondary antibodies diluted in TTBS at 1:500 ...
• Efficient scar-free knock-ins of several kilobases by engineered CRISPR/Cas endonucleases

  Tom Schreiber, et al., bioRxiv - Molecular Biology 2023

  Quote: ... Cas9-specific antibody (Santa Cruz, 7A9-3A3; 1:150 dilution) and anti-mouse antibody (Sante Cruz ...