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5651 - 5700 of 8862 citations for 6 1 4 dioxa 8 azaspiro 4.5 decan 8 yl 3 hydroxy 2 iminopyrimidin 4 amine since 2019

• Transplanted Autologous Neural Stem Cells Show Promise in Restoring Motor Function in Monkey Spinal Cord Injury

  Razieh Jaberi, et al., bioRxiv - Neuroscience 2023

  Quote: ... and anti-MBP (1:200, Santa cruz, sc-271524, USA). The primary antibodies were washed out with PBS-T ...
• Lysosomal cystine export regulates mTORC1 signaling to guide kidney epithelial cell fate specialization

  Marine Berquez, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-cathepsin D (Santa Cruz Biotechnology, sc-6486, 1:500), anti-S6 Ribosomal Protein (Cell Signaling Technology ...
• Dopamine receptor 1 on CaMKII-positive neurons within claustrum mediates adolescent cocaine exposure-induced anxiety-like behaviors and electro-acupuncture therapy

  Liying Chen, et al., bioRxiv - Neuroscience 2023

  Quote: ... mouse anti-CaMKIIα (1:100, RRID: AB_626789, Santa Cruz, USA) and rabbit anti-D1R (1:100 ...
• The DUSP1 on CaMKII-positive neurons in mPFC mediates adolescent cocaine exposure-induced higher sensitivity to cocaine during adulthood

  Xiaoyan Wei, et al., bioRxiv - Neuroscience 2023

  Quote: ... mouse anti-CaMKIIα (1:100, SC-13141, Santa Cruz, USA) and mouse anti-CaMKIIα (1:200 ...
• Shedding light on human olfaction: electrophysiological recordings from sensory neurons in acute slices of olfactory epithelium

  Andres Hernandez-Clavijo, et al., bioRxiv - Neuroscience 2023

  Quote: ... polyclonal rabbit anti-AC3 (1:100; sc-588, Santa Cruz) and polyclonal rabbit anti-TMEM16B (1:200 ...
• A human embryonic limb cell atlas resolved in space and time

  Bao Zhang, et al., bioRxiv - Developmental Biology 2023

  Quote: ... Primary antibodies for RUNX2 (1:50, Santa Cruz, sc-390715), THBS2 (1:100 ...
• Effects of canagliflozin and irbesartan on renal fibrosis in Dahl salt-sensitive rats

  Jianlong Zhai, et al., bioRxiv - Molecular Biology 2022

  Quote: ... anti-Smad7 (sc-265846; Santa Cruz Biotechnology, USA; 1:1000), and anti-glyceraldehyde-3-phosphate dehydrogenase (GAPDH ...
• Mice with renal-specific alterations of stem cell-associated signaling develop symptoms of chronic kidney disease but surprisingly no tumors

  Adam Myszczyszyn, et al., bioRxiv - Cell Biology 2023

  Quote: ... and mouse anti-AQP3 (1:50, Santa Cruz, sc-518001) primary antibodies or with Biotinylated LTL (1:300 ...
• Mice with renal-specific alterations of stem cell-associated signaling develop symptoms of chronic kidney disease but surprisingly no tumors

  Adam Myszczyszyn, et al., bioRxiv - Cell Biology 2023

  Quote: ... and mouse anti-p21 (1:100, Santa Cruz, sc-6246) primary antibodies ...
• Mutant Prion Protein Endoggresomes are Hubs for Local Axonal Organelle-Cytoskeletal Remodeling

  Tai Chaiamarit, et al., bioRxiv - Cell Biology 2023

  Quote: ... goat anti-KLC1 (V-17) (1:100, Santa Cruz Biotechnology); mouse anti-KIF1A (16/KIF1A ...
• Mechanical forces across compartments coordinate cell shape and fate transitions to generate tissue architecture

  Clémentine Villeneuve, et al., bioRxiv - Developmental Biology 2022

  Quote: ... rabbit anti-Vimentin (Santa Cruz, sc-7557-R; 1:100), rabbit anti-Sox9 (Cell Signalling ...
• A chemical probe to modulate human GID4 Pro/N-degron interactions

  Dominic D.G Owens, et al., bioRxiv - Molecular Biology 2023

  Quote: ... Muskelin (C-12, sc-398956, Santa Cruz Biotechnology, 1:1000), ARMC8 (E-1 ...
• Regulation of oncogene-induced senescence by the MRE11 and TREX1 nucleases

  Hervé Técher, et al., bioRxiv - Molecular Biology 2023

  Quote: ... anti-p53 (1/500, Santa Cruz, clone DO7 sc-47698). Following antibodies were purchased from Abcam ...
• RNF43 mutations facilitate colorectal cancer metastasis via formation of a tumour-intrinsic niche

  Jeroen M. Bugter, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and stained against APC (sc-7930, Santa Cruz, 1:1.000) and Actin (691001 ...
• Primordial germ cell DNA demethylation and development require DNA translesion synthesis

  Pranay Shah, et al., bioRxiv - Developmental Biology 2023

  Quote: ... anti-TFAP2C (1:100, catalog no. sc-12762; Santa Cruz); anti-SOX17 (1:200 ...
• A self-renewing biomimetic skeletal muscle construct engineered using induced myogenic progenitor cells

  Inseon Kim, et al., bioRxiv - Bioengineering 2023

  Quote: ... and anti-myogenin (F5D) (1:250, Santa Cruz, sc-12732). The secondary antibodies used in this study were Goat Anti-Mouse IgG2b (Alexa Fluor 546 ...
• Virally induced lipid droplets are a platform for innate immune signalling complexes

  EA Monson, et al., bioRxiv - Immunology 2023

  Quote: ... mouse monoclonal αACOX1 (1:1000; sc-517306, Santa Cruz Biotechnology), rabbit monoclonal αPerilipin-2 (1:2000 ...
• Virally induced lipid droplets are a platform for innate immune signalling complexes

  EA Monson, et al., bioRxiv - Immunology 2023

  Quote: ... mouse monoclonal αmfn1 (1:1000; sc-166644, Santa Cruz Biotechnology), mouse monoclonal αACOX1 (1:1000 ...
• MCT4 and CD147 co-localize with MMP14 in invadopodia and autolysosomes and collectively stimulate breast cancer cell invasion by increasing extracellular matrix degradation

  Signe Meng, et al., bioRxiv - Cancer Biology 2023

  Quote: ... against MCT4 (#376140) and LAMP-1 (#20011) from Santa Cruz; against MMP14 (#271840 and #192782) ...
• A CRISPR screen of HIV dependency factors reveals CCNT1 is non-essential in T cells but required for HIV-1 reactivation from latency

  Terry L Hafer, et al., bioRxiv - Microbiology 2023

  Quote: ... mouse α-CCNT2 (Santa Cruz Biotechnology, sc-81243, 1:500), and rabbit α-actin (Sigma-Aldrich ...
• CLOCK Mediates Delay in Cardiac Myofibroblast Formation and Attenuates Progression of Myocardial Fibrosis through Inhibition of Smad 3 Transcriptional Activity

  Yongqiao Zhou, et al., bioRxiv - Molecular Biology 2023

  Quote: ... and anti-GAPDH (sc-365062, 1:3000, Santa Cruz Biotechnology). Following primary antibody incubation ...
• Enhanced microglial dynamics and paucity of tau seeding in the amyloid plaque microenvironment contributes to cognitive resilience in Alzheimer’s disease

  Nur Jury-Garfe, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-ARP2 (E-12) (1:100, sc-166103, Santa Cruz) and anti-LAMP2 (H4B4 ...
• CD20 is a mammalian odorant receptor expressed in a subset of olfactory sensory neurons that mediates innate avoidance of predators

  Hao-Ching Jiang, et al., bioRxiv - Animal Behavior and Cognition 2023

  Quote: ... goat anti-MS4A1 (1:50, Santa Cruz Biotechnology, #sc-7735), rat anti-MS4A1 (1:100 ...
• Ser149 is another potential 14-3-3 ε binding site of Cdc25B in the G2/M transition of mouse fertilized eggs

  Wen-Ning He, et al., bioRxiv - Cell Biology 2023

  Quote: ... and rabbit anti-β-actin (1:400) (Santa Cruz Biotechnology). For detection ...
• GTPBP8 is required for mitoribosomal biogenesis and mitochondrial translation

  Liang Wang, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse anti-myc (1:1000, sc-40, Santa Cruz Biotechnology), mouse anti-NDUFA9 (1:1000 ...
• GTPBP8 is required for mitoribosomal biogenesis and mitochondrial translation

  Liang Wang, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse anti-TOM20 (1:200, sc-17764, Santa Cruz Biotechnology), mouse anti-myc (1:100 ...
• Serine ubiquitination of p62 regulates Nrf2 dependent redox homeostasis

  Rukmini Mukherjee, et al., bioRxiv - Cell Biology 2023

  Quote: ... HO1 (cat no: sc-136960, Santa Cruz Biotechnology, 1:2000), NQO1 (ab34173 ...
• The oncogene cyclin D1 promotes bipolar spindle integrity under compressive force

  Renaldo Sutanto, et al., bioRxiv - Cell Biology 2023

  Quote: ... Normal mouse IgG (1:100, Santa Cruz Biotechnology sc-2025) was used as a block before incubating in pre-conjugated mouse anti-α-tubulin DM1α Alexa Fluor 488 ...
• Histone lactylation antagonizes senescence and skeletal muscle aging via facilitating gene expression reprogramming

  Xuebin Zhang, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-β-ACTIN (Santa Cruz Biotechnology, sc-47778, 1:1000), anti-α-TUBULIN (Sigma ...
• Endocytosis Inhibitors Block SARS-CoV-2 Pseudoparticle Infection of Mink Lung Epithelium

  Ann Song, Rattapol Phandthong, Prue Talbot, bioRxiv - Cell Biology 2023

  Quote: ... mouse anti-TMPRSS2 (1:200; Santa Cruz Biotechnology, Dallas, TX), and mouse-EEA1 (1:200 ...
• Nuclear MTHFD2 secures mitosis progression by preserving centromere integrity

  Natalia Pardo-Lorente, et al., bioRxiv - Cell Biology 2023

  Quote: ... and VDAC1/Porin (Santa Cruz Biotechnology; #sc-390996; 1:200). The following secondary antibodies were used ...
• Somatic mutation of Afadin leads to anchorage independent survival and metastatic growth of breast cancer through αE-catenin dependent destabilization of the adherens junction

  Max A.K. Ratze, et al., bioRxiv - Cancer Biology 2023

  Quote: ... rabbit anti-GFP (1:500; sc-8334, Santa Cruz Biotechnology), and goat anti-AKT (1:1,000 ...
• 3D human retinal organoid model for the study of early diabetic retinopathy

  Luisa de Lemos, et al., bioRxiv - Neuroscience 2023

  Quote: ... mouse anti-SOD1 (1:1000, sc-31989, Santa Cruz Biotechnology), rabbit anti-SOD2 (1:1000 ...
• 3D human retinal organoid model for the study of early diabetic retinopathy

  Luisa de Lemos, et al., bioRxiv - Neuroscience 2023

  Quote: ... mouse anti-Catalase (1:500, sc-271803, Santa Cruz Biotechnology), mouse anti-SOD1 (1:1000 ...
• Drug-induced change in transmitter identity is a shared mechanism generating cognitive deficits

  Pratelli Marta, et al., bioRxiv - Neuroscience 2023

  Quote: ... goat-anti-doublecortin (Santa Cruz, sc-8066, RRID:AB_2088494, 1:300) and rabbit-anti-Ki67 (Cell Signaling ...
• Preserved striatal innervation and motor function despite severe loss of nigral dopamine neurons following mitochondrial dysfunction induced by mtDNA mutations

  Thomas Paß, et al., bioRxiv - Neuroscience 2023

  Quote: ... and monoclonal α-TH (1:500; Santa Cruz, sc-25269). Sections were washed (0.2% Triton X-100 in PBS ...
• Neurotrophin-3 from the dentate gyrus supports postsynaptic sites of mossy fiber-CA3 synapses and contextual memory

  Ji-Wei Tan, et al., bioRxiv - Neuroscience 2023

  Quote: ... goat anti-doublecortin (1:200; Santa Cruz Biotechnology #SC-8066), rabbit anti-GluR1 (1:250 ...
• Assessment of technical and clinical utility of a bead-based flow cytometry platform for multiparametric phenotyping of CNS-derived extracellular vesicles

  Alexandra Brahmer, et al., bioRxiv - Neuroscience 2023

  Quote: ... CD81 (1:1000 dilution, #B-11, Santa Cruz, Heidelberg, Germany), Syntenin (1:3000 dilution ...
• The Interferon γ Pathway Enhances Pluripotency and X-Chromosome Reactivation in iPSC reprogramming

  Mercedes Barrero, et al., bioRxiv - Genetics 2023

  Quote: ... mouse anti PP1α 1:1000 (Santa Cruz Biotech., sc-7482), rabbit anti STAT3 1:1000 (Cell Signaling ...
• Membrane-bound Interleukin-1α mediates leukocyte adhesion during atherogenesis

  Christina Mäder, et al., bioRxiv - Immunology 2023

  Quote: ... The primary antibodies hIL-1α (1:50, Santa Cruz, USA) and IL1R1 Polyclonal Antibody (1:100 ...
• The differentiation and integration of the hippocampal dorsoventral axis are controlled by two nuclear receptor genes

  Xiong Yang, et al., bioRxiv - Developmental Biology 2023

  Quote: ... mouse anti-GAPDH (1:1000, Santa Cruz, Cat # sc-32233). The following secondary antibodies were applied in the study ...
• The differentiation and integration of the hippocampal dorsoventral axis are controlled by two nuclear receptor genes

  Xiong Yang, et al., bioRxiv - Developmental Biology 2023

  Quote: ... goat anti-Dcx (1:500, Santa Cruz, Cat # sc-8066). The following secondary antibodies were used in the study ...
• The differentiation and integration of the hippocampal dorsoventral axis are controlled by two nuclear receptor genes

  Xiong Yang, et al., bioRxiv - Developmental Biology 2023

  Quote: ... rabbit anti-Nestin (1:200, Santa Cruz, Cat # sc-20978), goat anti-Dcx (1:500 ...
• The differentiation and integration of the hippocampal dorsoventral axis are controlled by two nuclear receptor genes

  Xiong Yang, et al., bioRxiv - Developmental Biology 2023

  Quote: ... goat anti-Lhx2 (1:200, Santa Cruz, Cat # sc-19344), goat anti-Lhx5 (1:200 ...
• Nuclear damage in LMNA mutant iPSC-derived cardiomyocytes is associated with impaired lamin localization to the nuclear envelope

  Melanie Wallace, et al., bioRxiv - Cell Biology 2023

  Quote: ... The Lamin A/C antibody used (Santa Cruz; E-1) targeted the N-terminus (AA 2-29 ...
• UBAP2L drives scaffold assembly of nuclear pore complexes at the intact nuclear envelope

  Yongrong Liao, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse monoclonal anti-TIA-1 (Santa Cruz Biotechnology, sc-166247), mouse monoclonal anti-FXR1 (Millipore ...
• Capsicum chinense Jacq. derived glutaredoxin (CcGRXS12) alters phytohormonal pathways and redox status of the cells to confer resistance against pepper mild mottle virus (PMMoV-I)

  R. M. Saravana Kumar, et al., bioRxiv - Biochemistry 2023

  Quote: ... GFP specific polyclonal antibody (1/250; Santa Cruz Biotechnology, INC.) and PMMoV-I CP (1/1000 ...
• Tetherin antagonism by SARS-CoV-2 enhances virus release: multiple mechanisms including ORF3a-mediated defective retrograde traffic

  Hazel Stewart, et al., bioRxiv - Cell Biology 2022

  Quote: ... mouse anti-VPS35 (Santa Cruz, B-5, IF 1:300), mouse anti-CD63 (BioLegend ...
• Cystin is required for maintaining fibrocystin (FPC) levels and safeguarding proteome integrity in mouse renal epithelial cells A mechanistic connection between the kidney defects in cpk mice and human ARPKD

  Yiming Zhang, et al., bioRxiv - Cell Biology 2023

  Quote: ... β-actin (mouse, mAb, Santa Cruz; sc-47778; 1:3000), Ift88 (rabbit pAb ...
• Panton-Valentine leukocidin-induced neutrophil extracellular traps lack antimicrobial activity and are readily induced in patients with recurrent PVL⁺-Staphylococcus aureus infections

  Hina Jhelum, et al., bioRxiv - Immunology 2022

  Quote: ... 10 µg/ml CD88 (S5/1)-FITC (Santa Cruz Biotechnology) and 10 µg/ml anti-human C5L2-APC (BioLegend ...