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6001 - 6050 of 8862 citations for 6 1 4 dioxa 8 azaspiro 4.5 decan 8 yl 3 hydroxy 2 iminopyrimidin 4 amine since 2019

• Oncogenic c-Myc induces replication stress by increasing cohesins chromatin occupancy

  Silvia Peripolli, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-c-Myc (Santa Cruz Biotechnology 9E10 sc-40 1:1000), anti-CHK1 (Cell Signalling Technology 2360 1:1000) ...
• MYCN mediates cysteine addiction and sensitizes to ferroptosis

  Hamed Alborzinia, et al., bioRxiv - Cancer Biology 2021

  Quote: ... SAHH (A-11) (AHCY antibody, sc-271389, Santa Cruz, 1:1000) or ß-actin-conjugated (ab20272 ...
• RGG-motif protein Sbp1 is required for Processing body (P-body) disassembly

  Raju Roy, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-GFP (Santa Cruz, catalog no. sc-9996; 1:1000 dilution), and anti-PGK1 (Abcam ...
• Chromosome segregation fidelity is controlled by small changes in phospho-occupancy at the kinetochore-microtubule interface

  Thomas J. Kucharski, et al., bioRxiv - Cell Biology 2021

  Quote: ... PP2A B56 Gamma (Santa Cruz A-11; IB at 1:500), PP2A B56 Delta (Santa Cruz H-11 ...
• Chromosome segregation fidelity is controlled by small changes in phospho-occupancy at the kinetochore-microtubule interface

  Thomas J. Kucharski, et al., bioRxiv - Cell Biology 2021

  Quote: ... PP2A B56 Delta (Santa Cruz H-11; IB at 1:500), PP2A B56 Epsilon (Aviva Systems Biology RP56694_P050 ...
• CDK4/6 inhibitors induce replication stress to cause long-term cell cycle withdrawal

  Lisa Crozier, et al., bioRxiv - Cancer Biology 2021

  Quote: ... rabbit anti-p21 (H-164) (Santa Cruz, sc-756; 1/250), mouse anti-p53 (DO-1 ...
• The spindle assembly checkpoint and the spatial activation of Polo kinase determine the duration of cell division and prevent neural stem cells tumor formation

  Emmanuel Gallaud, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-PKCζ (C-20) (rabbit, 1:250, Santa Cruz sc-216), anti-Miranda (rat ...
• Receptor Activity-Modifying Protein 2 (RAMP2) alters glucagon receptor trafficking in hepatocytes with functional effects on receptor signalling

  Emma Rose McGlone, et al., bioRxiv - Cell Biology 2021

  Quote: ... secondary sc-516102 at 1/1,000 (both from Santa Cruz Biotechnology); and anti-GAPDH mab374 at 1/500 dilution (Merck) ...
• Chromosome length and gene density contribute to micronuclear membrane stability

  Anna E Mammel, et al., bioRxiv - Cell Biology 2021

  Quote: ... rabbit anti-Lamin B1 (1:100; sc-365214, Santa Cruz Biotechnology), rabbit anti-Lamin A (1:500 ...
• Rad51 is a druggable target that sustains replication fork progression upon DNA replication stress

  Sònia Feu, et al., bioRxiv - Cell Biology 2022

  Quote: ... Lamin B (Santa Cruz Biotechnology, M-20 sc-6217; 1/200), GAP120 (Santa Cruz Biotechnology ...
• Rad51 is a druggable target that sustains replication fork progression upon DNA replication stress

  Sònia Feu, et al., bioRxiv - Cell Biology 2022

  Quote: ... Cyclin A2 (Santa Cruz Biotechnology, H-432 sc-751; 1/500), P-Chk1 S296 (Cell Signaling ...
• Pathogenic variants of sphingomyelin synthase SMS2 disrupt lipid landscapes in the secretory pathway

  Tolulope Sokoya, et al., bioRxiv - Cell Biology 2022

  Quote: ... mouse monoclonal anti-SMS2 (Santa Cruz, sc-293384; IB 1:1,000), mouse monoclonal anti-β-actin (Sigma ...
• GDNF-RET signaling and EGR1 form a positive feedback loop that promotes tamoxifen resistance via cyclin D1

  Brooke A. Marks, et al., bioRxiv - Molecular Biology 2022

  Quote: ... Anti-p-ELK-1 antibody (B4) (Santa Cruz, cat# sc-8406x) was used at 5ug ...
• The Shigella type III effector protein OspB is a cysteine protease

  Thomas E. Wood, et al., bioRxiv - Microbiology 2022

  Quote: ... anti-α-tubulin (Santa Cruz, sc-53030; diluted to 1:1000), anti-FLAG (Sigma ...
• Development of opioid-induced hyperalgesia depends on reactive astrocytes controlled by Wnt5a signaling

  Xin Liu, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-β-actin (1:1000; Santa Cruz Biotechnology, sc-1616-R), anti-IL-1β (1:500 ...
• Imbalance of Neuregulin1-ErbB2/3 signaling underlies altered myelin homeostasis in models of Charcot-Marie-Tooth disease type 4H

  Lara El-Bazzal, et al., bioRxiv - Neuroscience 2022

  Quote: ... goat anti-gapdh (1:1000) (#sc-48167, Santa Cruz Biotechnology, USA), mouse anti-tubulin (1:4000 ...
• Dopamine and ALK4 signaling synergize to induce PCBP1-mediated alternative splicing of FosB and sustained behavioral sensitization to cocaine

  Favio A. Krapacher, et al., bioRxiv - Neuroscience 2022

  Quote: ... rabbit anti DARPP-32 (1:500, sc-11365, Santa Cruz Biotech); mouse anti D1 (1:500 ...
• The BAF A12T mutation reduces BAF affinity to lamin A/C, preventing its recruitment to nuclear ruptures in Nestor Guillermo Progeria Syndrome cells

  A.F.J. Janssen, et al., bioRxiv - Cell Biology 2022

  Quote: ... mouse anti-lamin A/C (Santa Cruz, sc-376248, 1/500) and mouse anti-lamin A/C (Santa Cruz ...
• The BAF A12T mutation reduces BAF affinity to lamin A/C, preventing its recruitment to nuclear ruptures in Nestor Guillermo Progeria Syndrome cells

  A.F.J. Janssen, et al., bioRxiv - Cell Biology 2022

  Quote: ... mouse anti-lamin A/C (Santa Cruz, #sc-7292, 1/500), mouse anti-lamin B1 (Santa Cruz ...
• Skeletal muscle-derived extracellular vesicles are altered with chronic contractile activity

  Patience O. Obi, et al., bioRxiv - Cell Biology 2022

  Quote: ... mouse monoclonal anti-CD81 (sc-166029, Santa Cruz Biotechnology, 1:200), rabbit polyclonal anti-Flotillin-1 (F1180 ...
• Develop an efficient and specific AAV based labeling system for Muller glia in mice

  Yanxia Gao, et al., bioRxiv - Neuroscience 2022

  Quote: ... Mouse-anti-PKC α (1:200, Santa Cruz Biotechnology, sc-8393), Rabbit-anti-Calbindin (1:200 ...
• 4-aminopyridine promotes accelerated skin wound healing via neurogenic-mediator expression

  Mashanipalya G. Jagadeeshaprasad, et al., bioRxiv - Neuroscience 2022

  Quote: ... mouse anti-SOX10 antibody (Santa Cruz Biotechnology, # sc-365692; 1:100), rabbit vimentin antibody (Thermo Fisher ...
• 4-aminopyridine promotes accelerated skin wound healing via neurogenic-mediator expression

  Mashanipalya G. Jagadeeshaprasad, et al., bioRxiv - Neuroscience 2022

  Quote: ... mouse anti-SOX10 antibody (Santa Cruz Biotechnology, # sc-365692; 1:100), rabbit NGF antibody (Invitrogen ...
• CIGB-300 peptide targets the CK2 phospho-acceptor domain on Human Papillomavirus E7 and disrupts the Retinoblastoma (RB) complex in cervical cancer cells

  Ailyn C. Ramón, et al., bioRxiv - Cancer Biology 2022

  Quote: ... mouse monoclonal anti-HPV-18 E7 (1: 200) from Santa Cruz Biotechnology ...
• Janus Kinase 3 phosphorylation and the JAK/STAT pathway are positively modulated by follicle-stimulating hormone (FSH) in bovine granulosa cells

  Amir Zareifard, Francis Beaudry, Kalidou Ndiaye, bioRxiv - Molecular Biology 2022

  Quote: ... were purchased from Sigma while the pharmacological inhibitor JANEX-1 was purchased from Santa Cruz Biotechnology (SC-205354 ...
• Interaction with TopBP1 mediates human papillomavirus 16 E2 plasmid segregation/retention function and stability during the viral life cycle

  Apurva T. Prabhakar, et al., bioRxiv - Molecular Biology 2022

  Quote: ... Involucrin antibody (SY5) 1:200 (Santa Cruz; catalog no. sc-21748), Cyclin B1 (D5C10 ...
• GCNA is a histone binding protein required for spermatogonial stem cell maintenance

  Jonathan Ribeiro, Gerry P. Crossan, bioRxiv - Physiology 2022

  Quote: ... anti-PLZF (1:100, catalog no. sc-28319, Santa Cruz Biotechnology); anti-PLZF (1:300 ...
• The Conserved CNOT1 Interaction Motif of Tristetraprolin Regulates ARE-mRNA Decay Independently of the p38 MAPK-MK2 Kinase Pathway

  Alberto Carreño, Jens Lykke-Andersen, bioRxiv - Molecular Biology 2022

  Quote: ... rabbit polyclonal anti-GIGYF2 (Santa Cruz Biotechnology, sc-134708; 1:50), mouse monoclonal anti-14-3-3 (Santa Cruz Biotechnology ...
• A role for thalamic projection GABAergic neurons in circadian responses to light

  O. Brock, et al., bioRxiv - Neuroscience 2022

  Quote: ... goat anti-orexin B (1:1000, sc-8071, Santa Cruz Biotechnology), rabbit anti-MCH (1:1000 ...
• A role for thalamic projection GABAergic neurons in circadian responses to light

  O. Brock, et al., bioRxiv - Neuroscience 2022

  Quote: ... goat anti-orexin A (1:1000, sc-8070, Santa Cruz Biotechnology), rabbit c-fos (1:800 ...
• Hrq1/RECQL4 regulation is critical for preventing aberrant recombination during DNA intrastrand crosslink repair and is upregulated in breast cancer

  Thong T. Luong, et al., bioRxiv - Genetics 2022

  Quote: ... antibodies to detect Hrq1 and α-ubiquitin (1:1000 Santa Cruz) antibodies to detect ubiquitylated Hrq1-9xMyc or Hr1-7KR-6xHA ...
• Hrq1/RECQL4 regulation is critical for preventing aberrant recombination during DNA intrastrand crosslink repair and is upregulated in breast cancer

  Thong T. Luong, et al., bioRxiv - Genetics 2022

  Quote: ... Kar2 (rabbit polyclonal, Santa Cruz Biotechnology #sc-33630, 1:5000, WB); RECQL4 (rabbit polyclonal ...
• Hrq1/RECQL4 regulation is critical for preventing aberrant recombination during DNA intrastrand crosslink repair and is upregulated in breast cancer

  Thong T. Luong, et al., bioRxiv - Genetics 2022

  Quote: ... Clb2 (rabbit polyclonal, Santa Cruz Biotechnology #sc-9071, 1:2000, WB); Kar2 (rabbit polyclonal ...
• Hrq1/RECQL4 regulation is critical for preventing aberrant recombination during DNA intrastrand crosslink repair and is upregulated in breast cancer

  Thong T. Luong, et al., bioRxiv - Genetics 2022

  Quote: ... or Kar2 (α-Kar2, rabbit polyclonal, Santa Cruz biotechnology, 1:5000) as a loading control.
• Hrq1/RECQL4 regulation is critical for preventing aberrant recombination during DNA intrastrand crosslink repair and is upregulated in breast cancer

  Thong T. Luong, et al., bioRxiv - Genetics 2022

  Quote: ... The blots were probed using α-Myc (1:500 Santa Cruz) or α-HA (1:5000 Abcam ...
• Neuronal hemoglobin induces loss of dopaminergic neurons in mouse Substantia nigra, cognitive deficits and cleavage of endogenous α-synuclein

  Santulli Chiara, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-Spectrin ⍺ II 1:1000 (Santa Cruz, Cat. No. sc-46696), anti-TH 1:1000 (Millipore) ...
• Inner membrane complex proteomics reveals a palmitoylation cascade regulating intraerythrocytic development of malaria parasite

  Pengge Qian, et al., bioRxiv - Microbiology 2022

  Quote: ... mouse anti-Myc (IFA, 1:500, sc-40, Santa Cruz Biotechnology) and rabbit anti-Histone H3 (western blot ...
• Inner membrane complex proteomics reveals a palmitoylation cascade regulating intraerythrocytic development of malaria parasite

  Pengge Qian, et al., bioRxiv - Microbiology 2022

  Quote: ... mouse anti-HA (IFA, 1:500, sc-57592, Santa Cruz Biotechnology), rabbit anti-Myc (Western blot ...
• Efficient and sensitive profiling of RNA-protein interactions using TLC-CLIP

  Christina Ernst, Julien Duc, Didier Trono, bioRxiv - Molecular Biology 2022

  Quote: ... 1 μg of antibody against hnRNPc (Santa Cruz Biotechnology, sc-32308), RBM9 (Bethyl Laboratories ...
• Preclinical safety evaluation of continuous UV-A lighting in an operative setting

  Rachael Guenter, et al., bioRxiv - Molecular Biology 2022

  Quote: ... and the loading control GAPDH (1:1000, Santa Cruz sc-47724).
• Pro-apoptotic and anti-invasive properties underscore the tumor suppressing impact of myoglobin on subset of human breast cancer cells

  Mostafa A. Aboouf, et al., bioRxiv - Cancer Biology 2022

  Quote: ... mouse anti-p53 (DO-1) monoclonal antibody (Santa Cruz, #sc-126) 1:200 ...
• Low lamin A levels enhance confined cell migration and metastatic capacity in breast cancer

  Emily S. Bell, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Lamin A/C (N-18) (1/50, Santa Cruz Biotechnologies, AB_648152), Lamin A (H102 ...
• SUMOylation of ABCD3 restricts bile acid synthesis and regulates metabolic homeostasis

  Vanessa Goyon, et al., bioRxiv - Cell Biology 2022

  Quote: ... Hsp60 by mouse monoclonal antibodies (sc-136291, 1:1000, Santa Cruz), Hsp70 by rabbit polyclonal antibodies (ab137680 ...
• WDR82 mediated H3K4me3 is associated with tumor proliferation and therapeutic efficacy in pediatric high-grade gliomas

  Nitin Wadhwani, et al., bioRxiv - Cancer Biology 2022

  Quote: ... rabbit polyclonal anti-GAPDH (sc-25,778, 1:2000) from Santa Cruz Biotechnology ...
• SUMOylation of ABCD3 restricts bile acid synthesis and regulates metabolic homeostasis

  Vanessa Goyon, et al., bioRxiv - Cell Biology 2022

  Quote: ... CYP4A14 by goat polyclonal antibodies (sc-46087, 1:500, Santa Cruz), CYP7A1 by rabbit polyclonal antibodies (ab65596 ...
• KIF24 controls the clustering of supernumerary centrosomes in pancreatic ductal adenocarcinoma cells

  Yu Mashima, et al., bioRxiv - Cell Biology 2022

  Quote: ... and mouse anti-β-Actin (1:1000, Santa Cruz, sc-47778). A rabbit anti-KIF24-2 antibody was produced by immunizing a glutathione-S-transferase (GST ...
• Single cell analysis of population-wide nuclear and cytosolic drug responses using high-content FRET imaging: measuring protein kinase activation in rat primary striatal neurons

  Jace Jones-Tabah, et al., bioRxiv - Neuroscience 2021

  Quote: ... anti-cFos (1:2000, catalog #sc-52, Lot #C1010, Santa Cruz) and anti-beta tubulin (1:4000 ...
• Enforced dimerization between XBP1s and ATF6f enhances the protective effects of the unfolded protein response (UPR) in models of neurodegeneration

  René L. Vidal, et al., bioRxiv - Neuroscience 2020

  Quote: ... The following antibodies were used: Hsp90 (1:3,000; Santa Cruz Biotechnology), beta-actin (1:3,000 ...
• Enforced dimerization between XBP1s and ATF6f enhances the protective effects of the unfolded protein response (UPR) in models of neurodegeneration

  René L. Vidal, et al., bioRxiv - Neuroscience 2020

  Quote: ... and anti-HA 1:500 (Santa Cruz, Cat. n°SC-805). Bound antibodies were detected with peroxidase-coupled secondary antibodies incubated for 2 h at room temperature and the ECL system.
• Insulin-Like Growth Factor I Modulates Vulnerability to Stress Through Orexin Neurons

  ME Fernandez de Sevilla, et al., bioRxiv - Neuroscience 2020

  Quote: ... monoclonal anti-orexin-A (1:100 dilution, sc-80263, Santa Cruz), and polyclonal anti-tyrosine hydroxylase (1:1000 dilution ...