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5451 - 5500 of 8862 citations for 6 1 4 dioxa 8 azaspiro 4.5 decan 8 yl 3 hydroxy 2 iminopyrimidin 4 amine since 2019

• FMR1 loss results in early changes to intrinsic membrane excitability in human cellular models

  Sara G. Susco, et al., bioRxiv - Neuroscience 2020

  Quote: ... and anti-TRA-1-60 (Santa Cruz Biotechnology sc-21705). Antibodies used to assess tri-lineage potential were anti-AFP (Sigma A8452) ...
• Loss of function of the mitochondrial peptidase PITRM1 induces proteotoxic stress and Alzheimer’s disease-like pathology in human cerebral organoids

  Dina Ivanyuk, et al., bioRxiv - Neuroscience 2020

  Quote: ... mouse anti-VDAC1 (1:1000, Santa Cruz Biotechnologies #sc-390996).
• Loss of function of the mitochondrial peptidase PITRM1 induces proteotoxic stress and Alzheimer’s disease-like pathology in human cerebral organoids

  Dina Ivanyuk, et al., bioRxiv - Neuroscience 2020

  Quote: ... mouse anti-HSP60 (1:3000, Santa Cruz Biotechnologies #sc-271215); rabbit anti-LONP1 (1:3000 ...
• Loss of function of the mitochondrial peptidase PITRM1 induces proteotoxic stress and Alzheimer’s disease-like pathology in human cerebral organoids

  Dina Ivanyuk, et al., bioRxiv - Neuroscience 2020

  Quote: ... mouse anti-HSPA9 (1:3000, Santa Cruz Biotechnologies #sc-133137); mouse anti-HSP60 (1:3000 ...
• Long-term synaptic depression triggers local biogenesis of autophagic vesicles in dendrites and requires autophagic degradation

  Emmanouela Kallergi, et al., bioRxiv - Neuroscience 2020

  Quote: ... β III tubulin (Tuj1) (1:5000, Santa Cruz Biotechnology, sc-80005), actin (2Q1055 ...
• Human DICER helicase domain recruits PKR and modulates its antiviral activity

  Thomas C. Montavon, et al., bioRxiv - Microbiology 2021

  Quote: ... anti-TRBP (1:500, D-5 Santa Cruz sc-514124), anti-PKR (1:2500 ...
• Developmental Reactive Oxygen Species Target Histone Methylation to Individualize Stress resistance and Lifespan

  Daphne Bazopoulou, et al., bioRxiv - Molecular Biology 2019

  Quote: ... or anti-β-tubulin (Santa Cruz, sc-5274; 1:2,500) primary antibodies overnight at 4°C ...
• Loss of adipocyte identity through synergistic repression of PPARγ by TGF-β and mechanical stress

  Ewa Bielczyk-Maczyńska, et al., bioRxiv - Cell Biology 2019

  Quote: ... rabbit anti-CEBPα (Santa Cruz Biotech, sc-61, 1:1,000), mouse anti-YAP (Santa Cruz Biotech ...
• Loss of adipocyte identity through synergistic repression of PPARγ by TGF-β and mechanical stress

  Ewa Bielczyk-Maczyńska, et al., bioRxiv - Cell Biology 2019

  Quote: ... mouse anti-YAP (Santa Cruz Biotech, sc-101199, 1:500), chicken anti-GFP (Fisher Scientific ...
• DRP1-mediated regulation of mitochondrial dynamics determines the apoptotic response upon embryonic differentiation

  Barbara Pernaute, et al., bioRxiv - Developmental Biology 2019

  Quote: Primary antibodies used for immunofluorescence: Tom20 (1/100, Santa Cruz), ATP-b (1:100 ...
• Ubiquitin Ligase MARCH5 Regulates Apoptosis through Mediation of Stress-Induced and NOXA-Dependent MCL1 Degradation

  Seiji Arai, Sen Chen, Lisha Xie, Steven P. Balk, bioRxiv - Cancer Biology 2020

  Quote: ... anti-BIM (mouse, 1:500) (#sc-374358, Santa Cruz Biotechnology), anti-cleaved caspase 3 (CC3 ...
• Single-cell analysis of Foxp1-driven mechanisms essential for striatal development

  Ashley G. Anderson, et al., bioRxiv - Neuroscience 2019

  Quote: ... goat anti-FOXP2 (N-terminal) (1:500, Santa Cruz 21069), rabbit polyclonal anti-β-Tubulin (IB ...
• A RAD9-dependent cell cycle arrest in response to unresolved recombination intermediates in Saccharomyces cerevisiae

  Hardeep Kaur, GN Krishnaprasad, Michael Lichten, bioRxiv - Genetics 2019

  Quote: ... and rabbit anti-MYC (Santa Cruz, sc-789 1:250)] ...
• The nucleoporin ELYS regulates nuclear size by controlling NPC number and nuclear import capacity

  Predrag Jevtic, et al., bioRxiv - Cell Biology 2019

  Quote: ... and lamin B1 (Santa Cruz, sc-6217, goat, 1:500) in PBST with 1% BSA for 4 hours at room temperature or overnight at 4°C ...
• Ubiquitin Ligase MARCH5 Regulates Apoptosis through Mediation of Stress-Induced and NOXA-Dependent MCL1 Degradation

  Seiji Arai, Sen Chen, Lisha Xie, Steven P. Balk, bioRxiv - Cancer Biology 2020

  Quote: ... anti-MCL1 (mouse, 1:1000) (#sc-12756, Santa Cruz Biotechnology), anti-Mfn1 (mouse ...
• Ubiquitin Ligase MARCH5 Regulates Apoptosis through Mediation of Stress-Induced and NOXA-Dependent MCL1 Degradation

  Seiji Arai, Sen Chen, Lisha Xie, Steven P. Balk, bioRxiv - Cancer Biology 2020

  Quote: ... anti-Mfn1 (mouse, 1:1000) (#sc-166644, Santa Cruz Biotechnology), anti-MiD49 (SMCR7 ...
• Ubiquitin Ligase MARCH5 Regulates Apoptosis through Mediation of Stress-Induced and NOXA-Dependent MCL1 Degradation

  Seiji Arai, Sen Chen, Lisha Xie, Steven P. Balk, bioRxiv - Cancer Biology 2020

  Quote: ... anti-p53 (mouse, 1:1000) (#sc-126, Santa Cruz Biotechnology), anti-p62 (rabbit ...
• Regulation of eIF6 through multisite and sequential phosphorylation by GSK3β

  Courtney F. Jungers, et al., bioRxiv - Molecular Biology 2019

  Quote: ... or anti-eIF6 monoclonal antibody (1:350) (Santa Cruz Biotechnology) and incubated in a humidified chamber at room temperature (RT ...
• Rho-kinase mediates the anorexigenic action of melanocortin by suppressing AMPK

  Sang Soo Kim, et al., bioRxiv - Neuroscience 2019

  Quote: ... anti-mouse Gα12 (sc-515445, 1:100, Santa Cruz Biotechnology), or anti-mouse Gαs (sc-135914 ...
• Dock5 is a new regulator of microtubule dynamic instability through GSK3β inhibition in osteoclasts

  Sarah Guimbal, et al., bioRxiv - Cell Biology 2019

  Quote: ... rat anti-alpha tubulin (1/200, Santa Cruz, #sc-53030) or rabbit anti-Dock5 (1/100 ...
• p57Kip2 regulates embryonic haematopoietic stem cell numbers by controlling the size of the sympathoadrenal progenitor pool

  Chrysa Kapeni, et al., bioRxiv - Developmental Biology 2021

  Quote: ... and Sox10 (goat N-20, 1:250, Santa Cruz Biotechnology). The next day ...
• A single-cell transcriptomic and anatomic atlas of mouse dorsal raphe Pet1 neurons

  Benjamin W. Okaty, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-Pax5 (1:1000, goat polyclonal, Santa Cruz, sc-1974), anti-SATB2 (1:1000 ...
• A single-cell transcriptomic and anatomic atlas of mouse dorsal raphe Pet1 neurons

  Benjamin W. Okaty, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-Doublecortin (1:1000, goat polyclonal, Santa Cruz, SC-8066), and anti-Ki-67(1:1000 ...
• Neurodegeneration induces a developmental RNA processing program by calpain-mediated MBNL2 degradation

  Lee-Hsin Wang, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-Histone H3 (sc-8654, 1:5000, Santa Cruz Biotechnology).
• Simultaneous expression of UV and violet SWS1 opsins expands the visual palette in a group of freshwater snakes

  Einat Hauzman, et al., bioRxiv - Evolutionary Biology 2021

  Quote: ... goat anti-SWS1 (Santa Cruz Biotechnology; sc-14363; 1:200), rabbit anti-LWS (Chemicon International ...
• Tracheal motile cilia in mice require CAMSAP3 for formation of central microtubule pair and coordinated beating

  Hiroko Saito, et al., bioRxiv - Cell Biology 2021

  Quote: ... mouse monoclonal anti-Chibby (Santa Cruz sc-101551, 1:100). The following secondary antibodies were used ...
• Sex determination gene transformer regulates the male-female difference in Drosophila fat storage via the adipokinetic hormone pathway

  Lianna W. Wat, et al., bioRxiv - Physiology 2021

  Quote: ... and mouse anti-actin (1:100; Santa Cruz #sc-8432).
• Annexin A1 tripeptide mimetic increases sirtuin-3 to augment mitochondrial function and limit ischemic kidney injury

  Hagir Suliman, et al., bioRxiv - Physiology 2020

  Quote: ... PARK2 (1:500; Cat. No. sc-32282; Santa Cruz Biotechnology); light chain 3B protein (LC3I/II ...
• Transcriptional repression of Myc underlies AGO1’s tumour suppressor function

  Olga Zaytseva, et al., bioRxiv - Developmental Biology 2020

  Quote: ... Myc N (Rabbit 1 in 500 Santa Cruz d46-507), Fibrillarin (Rabbit 1 in 500 Abcam ab5821) ...
• Soft limbal niche maintains stem cell compartmentalization and function through YAP

  Swarnabh Bhattacharya, et al., bioRxiv - Cell Biology 2021

  Quote: ... mouse anti-YAP (1:400, Santa cruz biotechnology, sc-101199) and rabbit anti-GAPDH (1:1000 ...
• Mosquito defensins enhance Japanese encephalitis virus infection by facilitating virus adsorption and entry within mosquito

  Ke Liu, et al., bioRxiv - Microbiology 2020

  Quote: ... goat anti-mouse IgG-HRP antibody (1:10000; Santa Cruz), Alexa Fluor 405-conjugated anti-mouse IgG antibody (1:500 ...
• Chemogenetic manipulation of microglia inhibits neuroinflammation and neuropathic pain in mice

  Min-Hee Yi, et al., bioRxiv - Neuroscience 2020

  Quote: ... and GAPDH (1:1000; sc-32233, RRID:AB_627679, Santa Cruz Biotechnology). Membranes were incubated with horseradish peroxidase-conjugated goat anti-mouse IgG (1:3,000 ...
• Reactive Astrocytes Prevent Maladaptive Plasticity after Ischemic Stroke

  Markus Aswendt, et al., bioRxiv - Neuroscience 2021

  Quote: ... goat anti-Sox2 (1:200, sc-7379, Santa Cruz Biotechnology), rabbit anti S100 (1:200 ...
• Insulin-like growth factor 2 (IGF2) protects against Huntington’s disease through the extracellular disposal of protein aggregates

  Paula García-Huerta, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-polyUbiquitin 1:5000 (Santa Cruz, Cat. n° SC-8017), anti-DARPP32 1:1000 (Millipore ...
• Insulin-like growth factor 2 (IGF2) protects against Huntington’s disease through the extracellular disposal of protein aggregates

  Paula García-Huerta, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-GAPDH 1:2000 (Santa Cruz, Cat. n° SC-365062), anti-HA 1:500 (Santa Cruz ...
• The dynamic equilibrium of nascent and parental MCMs safeguards replicating genomes

  Hana Sedlackova, et al., bioRxiv - Cell Biology 2019

  Quote: ... PCNA (mouse, Santa Cruz, sc-56, 1:1000 for WB), RPA32-phospho-S33 (rabbit ...
• Mitotic checkpoint protein Mad1 is required for early Nup153 recruitment to chromatin and nuclear envelope integrity

  Ikram Mossaid, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-Mad1 (Santa Cruz, sc-67338; IF 1:100), rabbit anti-Mad2 (Covance ...
• Abnormal Cannabidiol protects pancreatic beta cells in mouse models of experimental Type 1 diabetes

  Isabel Gonzalez-Mariscal, et al., bioRxiv - Pharmacology and Toxicology 2020

  Quote: ... rabbit anti-insulin (1:100; sc-9168) from Santa Cruz Biotechnology ...
• Selective localization of Mfn2 near PINK1 enable its preferential ubiquitination by Parkin on mitochondria

  Marta Vranas, et al., bioRxiv - Biochemistry 2021

  Quote: ... rabbit anti-Mfn1 and anti-Mfn2 (1:2000, Santa Cruz), and mouse anti-VDAC1 (1:10000 ...
• Fibroblast growth factor-9 expression in airway epithelial cells amplifies the type I interferon response and alters influenza A virus pathogenesis

  Bradley E. Hiller, et al., bioRxiv - Immunology 2021

  Quote: ... anti-SCGB1A1 goat polyclonal antibody Sc9772 (1:200) (Santa Cruz). Embedding and sectioning were performed by the Musculoskeletal Histology and Morphometry Core at Washington University School of Medicine ...
• Unraveling the roles of Mast4 in amelogenesis via regulating DLX3 and stem cell maintenance of mouse incisors

  Dong-Joon Lee, et al., bioRxiv - Developmental Biology 2021

  Quote: ... anti-HA (sc-7392, Santa cruz Biotechnology, USA; 1:1000), anti-Lamin B (SC-374015 ...
• A drug-screening platform based on organotypic cultures identifies vulnerabilities to prevent local relapse and treat established brain metastasis

  Lucía Zhu, et al., bioRxiv - Cancer Biology 2020

  Quote: ... HSP70/ HSC70 W27 (1:500; sc-24; Santa Cruz Biotechnology), AHR (1:300 ...
• DNA damage response at telomeres boosts the transcription of SARS-CoV-2 receptor ACE2 during aging

  Sara Sepe, et al., bioRxiv - Cell Biology 2021

  Quote: ... rabbit polyclonal anti-53BP1 (1:1000, sc-22760, Santa Cruz), mouse monoclonal anti-phospho-Histone H2A.X (1:500 ...
• Cofilin pathology is a new player on α-synuclein-induced spine impairment in models of hippocampal synucleinopathy

  MI Oliveira da Silva, et al., bioRxiv - Neuroscience 2021

  Quote: ... and mouse anti-GAPDH 1:1000 (Santa Cruz, sc-166574) diluted in 5%milk/TBS-T or 5%BSA ...
• Previous estradiol treatment during midlife maintains transcriptional regulation of memory-related proteins by ERα in the hippocampus in a rat model of menopause

  Nina E. Baumgartner, et al., bioRxiv - Neuroscience 2021

  Quote: ... and loading control protein β-actin (Santa Cruz, 1:5000). Secondary antibodies conjugated to HRP were used ...
• Insulin-dependent maturation of newly generated olfactory sensory neurons after injury

  Akihito Kuboki, et al., bioRxiv - Neuroscience 2021

  Quote: ... and anti-c-Fos (rabbit IgG, 1:1,000; Santa Cruz Biotechnology Inc. ...
• The E3 ubiquitin ligase HECTD1 contributes to cell cycle progression through an effect on mitosis

  Natalie Vaughan, et al., bioRxiv - Cell Biology 2021

  Quote: ... Anti-Cyclin B1 (Santa Cruz Biotechnology, sc-245, 1/1,000), anti-phospho-Histone H3 (Ser28 ...
• Caveolae mediated endocytosis of VLDL particles in macrophages requires NPC1 and STARD3 for further lysosomal processing

  Lei Deng, et al., bioRxiv - Cell Biology 2021

  Quote: Human LPL F:1 (Santa Cruz Biotechnology, Inc., California, USA) and 5D2 antibodies were added to cell culture medium 2 hours prior to emulsion loading at the concentration of 2 μg/ml (1:100 dilution).
• Alleviation of neuropathic pain by over-expressing a soluble colony-stimulating factor 1 receptor

  Svetlana Gushchina, et al., bioRxiv - Neuroscience 2020

  Quote: ... Donkey anti-goat IgG-HRP (1:10,000, Santa Cruz Biotechnology) was applied to the membrane for 2 h at room temperature.
• Coupling adipose tissue architecture and metabolism via cytoophidia

  Jingnan Liu, et al., bioRxiv - Developmental Biology 2021

  Quote: ... goat anti CTPS (1:400, Santa Cruz Catalogue no.33304) was used as the primary antibody ...