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5401 - 5450 of 8862 citations for 6 1 4 dioxa 8 azaspiro 4.5 decan 8 yl 3 hydroxy 2 iminopyrimidin 4 amine since 2019

• The dark kinase STK32A regulates hair cell planar polarity opposite of EMX2 in the developing mouse inner ear

  Shihai Jia, et al., bioRxiv - Developmental Biology 2022

  Quote: ... and Oncomodulin/OCN (1:250; Santa Cruz Biotechnology SC-7466) as described above ...
• An evolutionarily conserved pacemaker role for HCN ion channels in smooth muscle

  Lei Yang, et al., bioRxiv - Physiology 2022

  Quote: ... and anti-uroplakin (H-180, Santa Cruz, at 1:50). Minimally cross-absorbed Alexa Flour secondary antibodies were used for primary antibody detections ...
• Targeted protein degradation reveals BET bromodomains as the cellular target of Hedgehog Pathway Inhibitor-1

  Meropi Bagka, et al., bioRxiv - Cell Biology 2022

  Quote: ... 1:500 mouse anti-BRD3 (Santa Cruz Biotechnology Inc., 2088C3a) 1:1000 rabbit anti-BRD4 (Bethyl Laboratories ...
• mTOR pathway inhibition stimulates pharmacologically induced nonsense suppression

  Amnon Wittenstein, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-APC (rabbit polyclonal; Santa Cruz; sc-7930, 1:500), anti-active β-catenin (rabbit polyclonal ...
• Live-Cell Tracking of γ-H2AX Kinetics Reveals the Distinct Modes of ATM and DNA-PK in Immediate Response to DNA Damage

  Watanya Trakarnphornsombat, Hiroshi Kimura, bioRxiv - Cell Biology 2022

  Quote: ... and mouse anti-GAPDH (1:1000; Santa Cruz Biotechnology; 6C5) diluted in Can-Get-Signal® Solution 1 (Toyobo ...
• Epithelial Plasticity and Innate Immune Activation Promote Lung Tissue Remodeling following Respiratory Viral Infection

  Andrew K. Beppu, et al., bioRxiv - Cell Biology 2022

  Quote: ... Goat polyclonal anti-p63(1:500, Santa Cruz, Sc-8609); Goat Polyclonal UGRP1/SCGB3A2 (1:1000 ...
• The RhoGEF Cysts couples apical polarity proteins to Rho and myosin activity at adherens junctions

  Jordan T. Silver, et al., bioRxiv - Cell Biology 2019

  Quote: ... anti-PKCζ (C-20; 1:100; rabbit polyclonal; Santa Cruz), and anti-Dlg (1:100 ...
• Cryo-EM structure of the human L-type amino acid transporter 1 in complex with glycoprotein CD98hc

  Yongchan Lee, et al., bioRxiv - Biochemistry 2019

  Quote: ... anti-CD98hc antibody (1:1,000, H-300; Santa Cruz Biotechnology), peroxidase goat anti-mouse IgG and peroxidase goat anti-rabbit IgG (1:10,000 ...
• DNA methylation is indispensable for leukemia inhibitory factor dependent embryonic stem cells reprogramming

  Baojiang Wu, et al., bioRxiv - Cell Biology 2020

  Quote: ... anti-SOX2 (Santa cruz, Catalog Number: sc-17320, 1:200), anti-H3K27me3 (Upstate ...
• A long noncoding RNA acts as a post-transcriptional regulator of heat shock protein 70 kDa synthesis in the cold hardy Diamesa tonsa under heat shock

  P. Bernabò, G Viero, V. Lencioni, bioRxiv - Zoology 2019

  Quote: ... Immunoblotting was performed using GAPDH (1:1,000, Santa Cruz Biotechnology) and HSP70 (1:800 ...
• STK11 is required for the normal program of ciliated cell differentiation in airways

  Qiqi Chu, et al., bioRxiv - Developmental Biology 2019

  Quote: ... goat anti-SOX2 antibody (Santa Cruz, sc-17320, 1:100), mouse anti-P63 (Santa Cruz ...
• A Ca²⁺-ATPase Regulates E-cadherin Biogenesis and Epithelial-Mesenchymal Transition in Breast Cancer Cells

  Donna K. Dang, et al., bioRxiv - Cancer Biology 2019

  Quote: ... ZO-1 (H-300) (Santa Cruz Biotechnology, cat#sc-10804), pYAP (Ser127 ...
• Extracellular Pgk1 enhances neurite outgrowth of motoneurons through Nogo66-independent targeting of NogoA

  Cheng Yung Lin, et al., bioRxiv - Developmental Biology 2019

  Quote: ... anti-neurofilament H (NF-H) (Santa Cruz; SC; 1:500) and acetyl-tubulin (Sigma ...
• Autophagy controls lipid droplet formation by fine-tuning NCoR1 levels

  Shun-saku Takahashi, et al., bioRxiv - Cell Biology 2019

  Quote: ... and lamin B (M-20, Santa Cruz Biotechnology; 1:200) were purchased from the indicated suppliers ...
• SLCs contribute to endocrine resistance in breast cancer: role of SLC7A5 (LAT1)

  Catherine M Sevigny, et al., bioRxiv - Cancer Biology 2019

  Quote: ... ER alpha (Cat# sc-543, 1:1,000; Santa Cruz Biotechnology), and β-Actin (Cat# 66009-1-Ig ...
• Regulation of human development by ubiquitin chain editing of chromatin remodelers

  David Beck, et al., bioRxiv - Genetics 2020

  Quote: ... anti-OCT4 (ac-8628, Santa Cruz, 1:1,000 in IB), anti-OCT4 (#75463 ...
• CRL5-dependent regulation of Arl4c and Arf6 controls hippocampal morphogenesis

  Jisoo S. Han, et al., bioRxiv - Developmental Biology 2020

  Quote: ... anti-Cux1 (1:50, Santa Cruz Antibodies #sc-13024, Discontinued), anti-Dkk3 (1:200 ...
• Mice with GNAO1 R209H Movement Disorder Variant Display Hyperlocomotion Alleviated by Risperidone

  Casandra L. Larrivee, et al., bioRxiv - Neuroscience 2019

  Quote: ... and anti-actin (goat; 1:1,000; sc-1615; Santa Cruz) antibodies diluted in Odyssey blocking buffer with 0.1% Tween-20 overnight at 4°C ...
• Impairments in contractility and cytoskeletal organisation cause nuclear defects in nemaline myopathy

  Jacob A Ross, et al., bioRxiv - Cell Biology 2019

  Quote: ... β-tubulin (clone TUB2.1, mouse monoclonal IgG1, Santa Cruz, 1:500); desmin (clone D33 ...
• Lineage reversion drives WNT independence in intestinal cancer

  Teng Han, et al., bioRxiv - Cancer Biology 2020

  Quote: ... mouse anti-Spp1 (1:200, Santa Cruz Biotechnology, #sc-21742). For immunohistochemistry ...
• Mitochondrial dysfunction is signaled to the integrated stress response by OMA1, DELE1 and HRI

  Xiaoyan Guo, et al., bioRxiv - Cell Biology 2019

  Quote: ... rabbit anti-Tom20 (Santa Cruz Biotechnology #sc-11415, 1:100); rabbit anti-Hsp60 (Cell Signaling Technology #12165 ...
• Dorsal-to-ventral neocortical expansion is physically primed by ventral streaming of early embryonic preplate neurons

  Kanako Saito, et al., bioRxiv - Neuroscience 2019

  Quote: ... anti-Cux1 (rabbit, sc-13024, Santa Cruz Biotechnology, 1:300), anti-GFP (rat ...
• Human colon-on-a-chip enables continuous in vitro analysis of colon mucus layer accumulation and physiology

  Alexandra Sontheimer-Phelps, et al., bioRxiv - Cell Biology 2019

  Quote: ... anti-MUC2 (H-9, sc-515106, Santa Cruz, 1:100), anti-mouse-IgG2b Alexa Fluor 546 (A-21143 ...
• Senescence of alveolar stem cells drives progressive pulmonary fibrosis

  Changfu Yao, et al., bioRxiv - Cell Biology 2019

  Quote: ... mouse anti-CDKN1A (1:100, Santa Cruz Biotechnologies, sc-6246), mouse-HTII-280 (IgM ...
• IRE1β negatively regulates IRE1α signaling in response to endoplasmic reticulum stress

  Michael J. Grey, et al., bioRxiv - Cell Biology 2019

  Quote: ... anti-XBP1 (M186, sc-7160 Santa Cruz Biotechnology, 1:200), and anti-βactin (AC-15 ...
• Kinesin KIF18A is a novel PUM regulated target promoting mitotic progression and survival of human male germ cell line - TCam-2

  Maciej Jerzy Smialek, et al., bioRxiv - Developmental Biology 2019

  Quote: ... and anti-PUM2 (Santa Cruz Biotechnology, sc-31535, 1:250) were used ...
• Distinct molecular signatures of fission predict mitochondrial degradation or proliferation

  Tatjana Kleele, et al., bioRxiv - Cell Biology 2020

  Quote: ... anti-alpha-Tubulin (Santa Cruz sc-5286, diluted 1:2000).
• High-throughput generation and phenotypic characterization of zebrafish CRISPR mutants of DNA repair genes

  Unbeom Shin, et al., bioRxiv - Developmental Biology 2020

  Quote: ... anti-PCNA (PC10) (Santa Cruz Biotechnology, sc-56, 1:2000), anti-histone H3 (upstate 07-690 ...
• Intestinal ferritinophagy is regulated by HIF-2α and is essential for systemic iron homeostasis

  Nupur K Das, et al., bioRxiv - Physiology 2020

  Quote: ... sc-30968 goat antibody at 1:200 (Santa Cruz Biotechnology); ferritin rabbit antibody at 1:1000 (Cell Signaling Technology) ...
• Early-life hypoxia alters adult physiology and reduces stress resistance and lifespan in Drosophila

  Danielle M Polan, et al., bioRxiv - Physiology 2020

  Quote: ... and anti-actin (1:1000, Santa Cruz Biotechnology, # sc-8432). Secondary antibodies were purchased from Santa Cruz Biotechnology (sc-2030 ...
• Sub-centrosomal mapping identifies augmin-γTuRC as part of a centriole-stabilizing scaffold

  Nina Schweizer, et al., bioRxiv - Cell Biology 2020

  Quote: ... mouse anti-ARL13B (sc-515784, Santa Cruz; IF, 1:100), rabbit anti-CEP192 24 (ExM ...
• Intraflagellar transport complex B proteins regulate the Hippo effector Yap1 during cardiogenesis

  Marina Peralta, et al., bioRxiv - Developmental Biology 2019

  Quote: ... Primary antibodies against Tbx18 (Santa Cruz sc-17869, 1:100), Wt1 (Santa Cruz sc-192 ...
• The Polycomb group protein Ring1 regulates dorsoventral patterning of the mouse telencephalon

  Hikaru Eto, et al., bioRxiv - Developmental Biology 2019

  Quote: ... goat antibodies to Neurog1 (Santa Cruz, sc-19231, 1:200) and rabbit antibodies to H2AK119ub (Cell Signaling Technology ...
• Acetylation-mediated phase control of the nucleolus regulates cellular acetyl-CoA responses

  Ryan Houston, et al., bioRxiv - Cell Biology 2020

  Quote: MDM2 (SMP14) Mouse mAb (1:1000, Santa Cruz, sc-965)
• YB-1 IS REQUIRED FOR THE GENESIS AND METASTATIC CAPACITY OF HUMAN BREAST CANCER

  Sylvain Lefort, et al., bioRxiv - Cancer Biology 2020

  Quote: ... such as anti-ACTIN (Santa Cruz, sc-1615, 1/10,000), anti-H3 (Cell Signaling Technology ...
• Enhancer transcription identifies cis-regulatory elements for photoreceptor cell types

  Rangarajan D. Nadadur, et al., bioRxiv - Molecular Biology 2019

  Quote: ... mouse anti-Rxrg (1:300, Santa Cruz Biotechnology, sc-514134). Secondary antibodies were from Jackson Immunoresearch.
• SARS-CoV-2 binding to ACE2 triggers pericyte-mediated angiotensin-evoked cerebral capillary constriction

  Chanawee Hirunpattarasilp, et al., bioRxiv - Neuroscience 2021

  Quote: ... and rabbit anti-PDGFRβ (Santa Cruz, sc-432, 1:200). Secondary antibodies used were Alexa fluor 488 donkey anti-goat (Invitrogen ...
• A conserved ubiquitin- and ESCRT-dependent pathway to regulate human lysosomal membrane proteins

  Weichao Zhang, et al., bioRxiv - Cell Biology 2020

  Quote: ... mouse anti-HRS (1:500, C-7, Santa Cruz Biotechnology), mouse anti-HA (1:1000 ...
• A conserved ubiquitin- and ESCRT-dependent pathway to regulate human lysosomal membrane proteins

  Weichao Zhang, et al., bioRxiv - Cell Biology 2020

  Quote: ... mouse anti-Vps22 (1:500, C-11, Santa Cruz Biotechnology), mouse anti-HRS (1:500 ...
• Lipidomic Profiling Reveals an Age-Related Deficiency of Skeletal Muscle Proresolving Mediators that Contributes to Maladaptive Tissue Remodeling

  James F. Markworth, et al., bioRxiv - Immunology 2020

  Quote: ... and rabbit polyclonal CD163 (Santa Cruz, sc-33560, 1:50). The following day ...
• Mechanistic dissection of global proteomic changes in rats with heart failure and preserved ejection fraction

  Daniel Soetkamp, et al., bioRxiv - Molecular Biology 2021

  Quote: ... or 1 µm Rottlerin (PKC δ inhibitor, Santa Cruz Biotechnology) or buffer (control).
• Anatomic position determines oncogenic specificity in melanoma

  Joshua M. Weiss, et al., bioRxiv - Cancer Biology 2021

  Quote: ... CRKL (B-1) sc-365092 Lot#B0819 (Santa Cruz Biotechnology) (used for human cell lines) ...
• Klebsiella pneumoniae hijacks the Toll-IL-1R protein SARM1 in a type I IFN-dependent manner to antagonize host immunity

  Claudia Feriotti, et al., bioRxiv - Microbiology 2021

  Quote: ... anti-AIM2 (anti-rabbit, 1:1000; sc- 515895, Santa Cruz), anti-NLRP3 (anti-mouse ...
• Bat influenza vectored NS1-truncated live vaccine protects pigs against heterologous virus challenge

  Jinhwa Lee, et al., bioRxiv - Microbiology 2020

  Quote: ... or anti-β-actin antibody (diluted 1:500, Santa Cruz) overnight at 4ºC ...
• Robust three-dimensional expansion of human adult alveolar stem cells and SARS-CoV-2 infection

  Jeonghwan Youk, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-HOPX (1:200, Santa Cruz Biotechnologies, sc-30216), and sheep anti-PDPN (1:200 ...
• A single-cell transcriptomic atlas of the adult Drosophila ventral nerve cord

  Aaron M. Allen, et al., bioRxiv - Neuroscience 2019

  Quote: ... and anti-AbdA (1:100, C-11 Santa Cruz Biotechnology). Secondary antibodies used included ...
• Discovery of Alstrom syndrome gene as a regulator of centrosome duplication in asymmetrically dividing stem cells in Drosophila

  Cuie Chen, Yukiko M. Yamashita, bioRxiv - Developmental Biology 2019

  Quote: ... rabbit anti-Vasa (d-26; 1:200; Santa Cruz Biotechnology); rabbit anti-Asl (1:2000 ...
• Sox2 modulation increases naïve pluripotency plasticity

  Kathryn Tremble, et al., bioRxiv - Developmental Biology 2020

  Quote: ... mouse monoclonal against Oct4 (1:100, Santa Cruz, sc-5279). Secondary antibodies were Alexa Fluor antibodies (ThermoFisher Scientific ...
• Surface topography is a context-dependent activator of TGF-β signaling in mesenchymal stem cells

  Steven Vermeulen, et al., bioRxiv - Cell Biology 2020

  Quote: ... and anti-SRF antibody (1:200; Santa Cruz; sc-335).
• The Pax6 master control gene initiates spontaneous retinal development via a self-organising Turing network

  Timothy Grocott, et al., bioRxiv - Developmental Biology 2019

  Quote: ... Primary antibody against HSC70 (Santa Cruz sc-7298; 1:2,500) was applied at 4°C overnight and secondary polyclonal goat anti-mouse-HRP (Agilent P0447 ...