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5301 - 5350 of 8862 citations for 6 1 4 dioxa 8 azaspiro 4.5 decan 8 yl 3 hydroxy 2 iminopyrimidin 4 amine since 2019

• Dopamine and ALK4 signaling synergize to induce PCBP1-mediated alternative splicing of FosB and sustained behavioral sensitization to cocaine

  Favio A. Krapacher, et al., bioRxiv - Neuroscience 2022

  Quote: ... mouse anti DAPP32 (1:750, sc-271111, Santa Cruz Biotech); rabbit anti DARPP-32 (1:500 ...
• Dopamine and ALK4 signaling synergize to induce PCBP1-mediated alternative splicing of FosB and sustained behavioral sensitization to cocaine

  Favio A. Krapacher, et al., bioRxiv - Neuroscience 2022

  Quote: ... mouse anti PCBP1 (1:200, sc-137249; Santa Cruz biotech) and chicken anti MAP2 (Abcam ...
• A CRISPR-del-based pipeline for complete gene knockout in human diploid cells

  Takuma Komori, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-p15 (Santa Cruz Biotechnology, sc-271791; WB 1:1000), anti-HSP90 (BD Biosciences ...
• Activation of the actin/MRTF-A/SRF signalling pathway in pre-malignant mammary epithelial cells by P-cadherin is essential for transformation

  Lídia Faria, et al., bioRxiv - Cancer Biology 2022

  Quote: ... mouse anti-MRTF-A (1:1000 Santa Cruz, SC-390324), mouse anti-HSC70 (1:8000 Santa Cruz ...
• The BAF A12T mutation reduces BAF affinity to lamin A/C, preventing its recruitment to nuclear ruptures in Nestor Guillermo Progeria Syndrome cells

  A.F.J. Janssen, et al., bioRxiv - Cell Biology 2022

  Quote: ... mouse anti-lamin B1 (Santa Cruz, sc-365214, 1/500), mouse anti-yH2AX (Millipore ...
• The BAF A12T mutation reduces BAF affinity to lamin A/C, preventing its recruitment to nuclear ruptures in Nestor Guillermo Progeria Syndrome cells

  A.F.J. Janssen, et al., bioRxiv - Cell Biology 2022

  Quote: ... mouse anti-lamin B1 (Santa Cruz, #sc-365214, 1/1000), rabbit anti-emerin (Proteintech ...
• Human septins in cells organize as octamer-based filaments mediating actin-membrane anchoring

  Carla Silva Martins, et al., bioRxiv - Cell Biology 2022

  Quote: ... rabbit anti-SEPT7 (1:200, Santa Cruz Biotechnology sc-20620) and rabbit anti-SEPT9 (1:2,000 ...
• Human septins in cells organize as octamer-based filaments mediating actin-membrane anchoring

  Carla Silva Martins, et al., bioRxiv - Cell Biology 2022

  Quote: ... rabbit anti-SEPT7 (1:200, Santa Cruz Biotechnology sc-20620) and rabbit anti-SEPT9 (1:4000 ...
• E-cadherin is sorted by Rab7 and Snx16 for polarised secretion via Myosin V

  Dajana Tanasic, Nicola Berns, Veit Riechmann, bioRxiv - Cell Biology 2022

  Quote: ... rabbit anti-aPKC 1:200 (Santa Cruz Biotechnology, sc-216)
• Evolution and antiviral activity of a human protein of retroviral origin

  John A. Frank, et al., bioRxiv - Molecular Biology 2022

  Quote: ... and 1:200 anti-Goat OCT4 (Santa Cruz Biotechnology, Inc)] in fresh blocking solution for 24 hours at 4°C ...
• Spatial modeling reveals nuclear phosphorylation and subcellular shuttling of YAP upon drug-induced liver injury

  Lilija Wehling, et al., bioRxiv - Molecular Biology 2022

  Quote: ... LATS1 (1:200, Santa Cruz Biotechnology, Dallas, USA, sc-398560), LATS2 (1:200 ...
• ISL1 is necessary for auditory neuron development and contributes towards tonotopic organization

  Iva Filova, et al., bioRxiv - Neuroscience 2022

  Quote: ... goat anti-prestin (Santa Cruz Biotechnology sc-22692, 1:50), rabbit anti-parvalbumin (Abcam ab11427 ...
• ISL1 is necessary for auditory neuron development and contributes towards tonotopic organization

  Iva Filova, et al., bioRxiv - Neuroscience 2022

  Quote: ... rabbit anti-calretinin (Santa Cruz Biotechnology sc-50453, 1:100), goat anti-prestin (Santa Cruz Biotechnology sc-22692 ...
• Filopodia-mediated basement membrane assembly at pre-invasive tumor boundaries

  Emilia Peuhu, et al., bioRxiv - Cell Biology 2022

  Quote: ... and BrdU (clone BU1/75 ICR1, Santa Cruz, 1:300). All samples were stained with DAPI (4′,6-diamidino-2-phenylindole ...
• ISL1 is necessary for auditory neuron development and contributes towards tonotopic organization

  Iva Filova, et al., bioRxiv - Neuroscience 2022

  Quote: ... goat anti-Neurod1 (Santa Cruz Biotechnology sc-1084, 1:100), anti-β tubulin III (Tuj1 ...
• Senescence rewires microenvironment sensing to facilitate anti-tumor immunity

  Hsuan-An Chen, et al., bioRxiv - Cancer Biology 2022

  Quote: ... p21 (F-5) (1:500, sc-6246, Santa Cruz Biotechnology), Phospho-Stat1 (Tyr701 ...
• Chromatin-associated microprocessor assembly is regulated by PRP40, the U1 snRNP auxiliary protein

  Agata Stepien, et al., bioRxiv - Molecular Biology 2022

  Quote: ... and anti-mouse (sc-2005, Santa Cruz Biotechnology, 1: 10,000). Input represents 1/10 of the protein sample.
• Lamin A/C phosphorylation at serine 22 is a conserved heat shock response to regulate nuclear adaptation during stress

  Laura Virtanen, et al., bioRxiv - Molecular Biology 2022

  Quote: ... rabbit polyclonal ERK1 (1:500; K-23, Santa Cruz Biotechnology), rabbit polyclonal ERK2 (1:500 ...
• Lamin A/C phosphorylation at serine 22 is a conserved heat shock response to regulate nuclear adaptation during stress

  Laura Virtanen, et al., bioRxiv - Molecular Biology 2022

  Quote: ... rabbit polyclonal ERK2 (1:500, c-14, Santa Cruz Biotechnology), rabbit monoclonal pERK1/2 (1:1000 ...
• BECN1 F121A mutation increases autophagic flux in aged mice and improves aging phenotypes in an organ-dependent manner

  Salwa Sebti, Zhongju Zou, Michael U. Shiloh, bioRxiv - Physiology 2022

  Quote: ... and anti-actin (sc-47778, Santa Cruz, 1:5,000 dilution) antibodies.
• Profiling skeletal muscle-derived secretome with differentiation and acute contractile activity

  Benjamin Bydak, et al., bioRxiv - Physiology 2022

  Quote: ... mouse monoclonal anti-CD81 (sc-166029, Santa Cruz, 1:200), mouse monoclonal anti-ARF6 (sc-7971 ...
• Profiling skeletal muscle-derived secretome with differentiation and acute contractile activity

  Benjamin Bydak, et al., bioRxiv - Physiology 2022

  Quote: ... mouse monoclonal anti-ARF6 (sc-7971, Santa Cruz, 1:200), mouse monoclonal anti-Apolipoprotein A1 (0650-0050 ...
• Defective mitochondrial-lysosomal axis promotes extracellular vesicles release of mitochondrial components in Huntington’s Disease

  Margarida Beatriz, et al., bioRxiv - Neuroscience 2022

  Quote: ... The antibody anti-TFAM (1:150, #sc-28200, Santa Cruz) were used for immunoelectron labeling ...
• PP1 inhibitor-2 promotes PP1γ positive regulation of synaptic transmission

  Karl Foley, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-PP1 (1:1,000; E-9, Santa Cruz Biotechnology, Inc.), and anti-GFP (1:1000 ...
• Dandy Walker-like malformations in mutant mice demonstrate a role for PDGF-C/PDGFRα signalling in cerebellar development

  Sara Gillnäs, et al., bioRxiv - Developmental Biology 2022

  Quote: ... mouse-anti-Cx43 (1:50, Santa Cruz Biotechnology, sc-271837), rabbit-anti-Calbindin (1:200 ...
• Stress-relief function of migrasomal autophagosome formed by inhibition of autophagosome/lysosome fusion

  Seon Yong Lee, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-ATG5 (1:500; Santa cruz Biotechnology, Cat. # sc-133158), anti-LC3B (Novus Biologicals ...
• Identification of epigenetic modulators as determinants of nuclear size and shape

  Andria Schibler, et al., bioRxiv - Cell Biology 2022

  Quote: ... and lamin B1 (Santa Cruz, sc-6217, goat, 1:500) in PBST with 1% BSA for 4 hours at room temperature or overnight at 4°C ...
• ssDNA is not superior to dsDNA as long HDR donors for CRISPR-mediated endogenous gene tagging in human diploid cells

  Akira Mabuchi, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-HNRNPA1 (Santa Cruz Biotechnology, sc-32301; WB 1:500), anti-mNG (Cell Signaling Technology ...
• Stabilization of E-cadherin adhesions by COX-2/GSK3β signaling is a targetable pathway in metastatic breast cancer

  Kuppusamy Balamurugan, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and C/EBPδ at 1:100 (Santa Cruz, sc-135733) with relevant positive and negative controls ...
• YAP and collagen remodelling support cell proliferation and tumour aggressiveness in uterine leiomyosarcoma

  Jordi Gonzalez-Molina, et al., bioRxiv - Cancer Biology 2022

  Quote: ... YAP/TAZ (63.7; sc-101199; Santa Cruz Biotechnology; 1:200), cleaved-caspase 3 (Asp175 ...
• Astroglial CD38 regulates social memory and synapse formation through SPARCL1 in the medial prefrontal cortex

  Tsuyoshi Hattori, et al., bioRxiv - Neuroscience 2022

  Quote: ... and anti-MAG (sc-15324, Santa Cruz Biotechnology, 1:500) ...
• Involvement of Brn3a-positive spinal dorsal horn neurons in the transmission of visceral pain in inflammatory bowel disease model mice

  Kazuhiko Nishida, et al., bioRxiv - Neuroscience 2022

  Quote: ... rabbit anti-PKCγ (1:100, Santa Cruz Biotechnology, sc-211), Alexa 594-conjugated donkey anti-goat IgG (1:300 ...
• Low lamin A levels enhance confined cell migration and metastatic capacity in breast cancer

  Emily S. Bell, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Lamin B (M-20) (1/100, Santa Cruz Biotechnologies, AB_648158), Ki67 (1/200 ...
• Low lamin A levels enhance confined cell migration and metastatic capacity in breast cancer

  Emily S. Bell, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Lamin B (M-20) (1/100, Santa Cruz Biotechnologies, AB_648158), HSPB1 (1/400 ...
• Re-direction of phagosomes to the recycling expulsion pathway by a fungal pathogen

  Lei-Jie Jia, et al., bioRxiv - Cell Biology 2022

  Quote: ... mouse monoclonal anti-GFP antibody (Santa Cruz, 1:1,000 dilution), mouse monoclonal anti-p11 antibody (BD ...
• Novel tumorigenic FOXM1-PTAFR-PTAF axis revealed by multi-omic profiling in TP53/CDKN2A-double knockout human gastroesophageal junction organoid model

  Hua Zhao, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Immunohistochemistry was performed using the automated Bond-Max autostainer by Leica for the following antibodies: AE1/AE3 (1:200, Santa Cruz). Images were acquired with a Lecia Inverted Confocal SP8 (Johns Hopkins Medicine Ross Imaging Center) ...
• Membrane compartmentalization of Ect2/Cyk4/Mklp1 and NuMA/dynein/dynactin is essential for cleavage furrow formation during anaphase

  Shrividya Sana, Ashwathi Rajeevan, Sachin Kotak, bioRxiv - Cell Biology 2022

  Quote: ... 1:5000 mouse anti-β-actin (Santa Cruz, sc-58673), 1:1000 rabbit anti-Prc1 (Santacruz ...
• A multiplexed in vivo approach to identify driver genes in small cell lung cancer

  Myung Chang Lee, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-CC10 (E-11, Santa Cruz sc-365992, 1:200), anti-HES1 (D6P2U ...
• Oxidative stress profiles of lymphoblasts from Amyotrophic Lateral Sclerosis patients with or without known SOD1 mutations

  Teresa Cunha-Oliveira, et al., bioRxiv - Cell Biology 2022

  Quote: ... glutathione reductase (1:1000, sc-133136, RRID: AB_2115652, Santa Cruz), SOD-2 (1:1000 ...
• On optimal temozolomide scheduling for slowly growing gliomas

  Berta Segura-Collar, et al., bioRxiv - Cancer Biology 2022

  Quote: ... mouse anti-GAPDH (1:1.500, Santa Cruz Biotechnology #sc-47724), rabbit anti-pTyr1068-EGFR (1:1.000 ...
• THE STABILIZATAION OF C-MYC BY THE NOVEL CELL CYCLE REGULATOR, SPY1, DECREASES EFFICACY OF BREAST CANCER TREATMENTS

  Rosa-Maria Ferraiuolo, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-phospho-c-Myc-T58 (Santa Cruz Biotechnology; 1:1000), Cyclin E1 (Abcam ...
• C9ORF72 dipeptide repeat proteins disrupt formation of GEM bodies and induce aberrant accumulation of survival of motor neuron protein

  Yuma Kato, et al., bioRxiv - Neuroscience 2021

  Quote: ... mouse anti-Gemin2 (IgG2b, sc-32806, Santa Cruz, 1:50), goat anti-GFP (600-101-215 ...
• Transthyretin promotes axon growth via regulation of microtubule dynamics and tubulin acetylation

  Jessica Eira, et al., bioRxiv - Neuroscience 2021

  Quote: ... mouse anti-spastin (1:500, Santa Cruz Biotechnology, sc-81624), mouse anti-βIII-tubulin (1:10,000 ...
• Transthyretin promotes axon growth via regulation of microtubule dynamics and tubulin acetylation

  Jessica Eira, et al., bioRxiv - Neuroscience 2021

  Quote: ... mouse anti-GAPDH (1:1,000; Santa Cruz Biotechnology, sc-166574) and rabbit anti-vinculin (3:10,000 ...
• TLR4-pathway impairs synaptic number and cerebrovascular functions through astrocyte activation following traumatic brain injury

  Juliana M Rosa, et al., bioRxiv - Neuroscience 2021

  Quote: ... Appropriate peroxidase-conjugated secondary antibodies (1:10000; Santa Cruz Biotechnology) were used to detect proteins by enhanced chemiluminescence ...
• Enforced dimerization between XBP1s and ATF6f enhances the protective effects of the unfolded protein response (UPR) in models of neurodegeneration

  René L. Vidal, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-HSP90 1:2,000 (Santa Cruz, Cat. n° SC-13119), anti-GAPDH 1:2,000 (Santa Cruz ...
• Enforced dimerization between XBP1s and ATF6f enhances the protective effects of the unfolded protein response (UPR) in models of neurodegeneration

  René L. Vidal, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-GAPDH 1:2,000 (Santa Cruz, Cat. n° SC-365062) and anti-HA 1:500 (Santa Cruz ...
• Nucleolin is expressed in human fetal brain development and reactivated in human glial brain tumors regulating angiogenesis and vascular metabolism

  Marc Schwab, et al., bioRxiv - Neuroscience 2020

  Quote: ... The mouse monoclonal nucleolin antibody C23 (1:20, Santa Cruz) was used and incubated overnight at 4°C ...
• Single-cell RNA-sequencing reveals thoracolumbar vertebra heterogeneity and rib-genesis in pigs

  Jianbo Li, et al., bioRxiv - Developmental Biology 2021

  Quote: ... and CD248 (mouse, 1:50, Santa Cruz Biotechnology, sc-377221). Secondary antibody used was anti-rabbit IgG (1:500 ...
• TBX5 drives Aldh1a2 expression to regulate a RA-Hedgehog-Wnt gene regulatory network coordinating cardiopulmonary development

  Scott A. Rankin, et al., bioRxiv - Developmental Biology 2021

  Quote: ... goat anti-Tbx5 (Santa Cruz Biotechnology sc-17866, 1:350). Secondary antibodies were donkey anti-Chicken 488 ...