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1351 - 1400 of 3059 citations for 6 Boc 1 oxa 6 azaspiro 3.3 heptan 3 one since 2019

• The LUBAC participates in Lysophosphatidic Acid-induced NF-κB Activation

  Tiphaine Douanne, et al., bioRxiv - Immunology 2020

  Quote: ... or with 10 ng.mL−1 TNFα (R&D Systems). The protease activity of MALT1 was blocked with 20 μM of Mepazine (Chembridge) ...
• Identifying dysregulated immune cell subsets following critical volumetric muscle loss with pseudo-time trajectories

  Lauren A. Hymel, et al., bioRxiv - Immunology 2021

  Quote: ... and PE-conjugated anti-SDF-1 (R&D Systems). 30μL of CountBright Absolute Counting Beads (C36950 ...
• A secreted proteomic footprint for stem cell pluripotency

  Philip Lewis, et al., bioRxiv - Cell Biology 2021

  Quote: ... 1/500 mouse anti-FGFR1 (R&D systems, MAB658); 1/1000 rabbit anti-Follistatin (Abcam ...
• Self-organized stem cell-derived human lung buds with proximo-distal patterning and novel targets of SARS-CoV-2

  E.A. Rosado-Olivieri, et al., bioRxiv - Developmental Biology 2021

  Quote: ... goat anti-TP63 (R&D Systems; BAF1916; 1:250), rabbit anti-proSPC (Seven Hills ...
• Single cell RNA sequencing analysis of mouse cochlear supporting cell transcriptomes with activated ERBB2 receptor, a candidate mediator of cochlear regeneration mechanisms

  Dorota Piekna-Przybylska, et al., bioRxiv - Neuroscience 2022

  Quote: ... goat anti-TIMP1 (1:100; R&D Systems; AF980), rabbit anti-CD44 (1:100 ...
• Excessive fluid shear stress-mediated Klf4 leads to arteriovenous pathogenesis

  Kuheli Banerjee, et al., bioRxiv - Molecular Biology 2022

  Quote: ... and anti-SOX17 (#AF1924, 1:200, R&D systems).
• Lung Tumor Microphysiological System with 3D Endothelium to Evaluate Modulators of T-Cell Infiltration

  Katrina M. Wisdom, et al., bioRxiv - Bioengineering 2022

  Quote: ... ICAM-1/CD54 (10ug/mL, R&D Systems, BBA3) blocking antibody ...
• The translational role of SOS1 in colorectal cancer

  Diego Alem, et al., bioRxiv - Cancer Biology 2022

  Quote: ... 10nM human gastrin I (R&D Systems, 3006/1), 500nM A83-01 (Selleckchem ...
• DLL3 REGULATES NOTCH SIGNALING IN SCLC

  Jun W. Kim, Julie H. Ko, Julien Sage, bioRxiv - Cancer Biology 2022

  Quote: ... and NCAM-PE (R&D Systems FAB7820P, 1:100) (Shue et al. ...
• Reorganizing Niche Architecture Still Preserves Organ Function in the Hair Follicle

  Haoyang Wei, et al., bioRxiv - Developmental Biology 2022

  Quote: ... mouse integrin alpha9 (AF3827, R&D Systems, 1:200), Sox2 monoclonal antibody ...
• Adipose mTORC2 is essential for arborization of sensory neurons in white adipose tissue and whole-body energy homeostasis

  Irina C Frei, et al., bioRxiv - Physiology 2022

  Quote: ... GAP43-pS41 (1:1000, R&D Systems, Cat#PPS006), Tyrosine hydroxylase (1:500 ...
• Real-time imaging of mitochondrial redox reveals increased mitochondrial oxidative stress associated with amyloid β aggregates in vivo in a mouse model of Alzheimer’s disease

  Maria Calvo-Rodriguez, et al., bioRxiv - Neuroscience 2022

  Quote: ... NeuN (1:500, R&D Systems Cat# MAB377, RRID:AB_2298767), Amyloid β (1:500 ...
• Parvalbumin protein controls inhibitory tone in the spinal cord

  Haoyi Qiu, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-Pax2 goat (1:1000, R&D Systems #AF3364), anti-Tlx3 rabbit (1:1000 ...
• Prox2+ and Runx3+ neurons regulate esophageal motility

  Elijah D. Lowenstein, et al., bioRxiv - Neuroscience 2022

  Quote: ... goat anti-CD117 (R&D Systems, AF1356, 1:400), sheep anti-nNos (Millipore ...
• Binucleated cells generated by nuclear movement during neural transdifferentiation from human bone marrow-derived mesenchymal cells

  Carlos Bueno, et al., bioRxiv - Neuroscience 2022

  Quote: ... and IGF-1 (10 ng/ml; R&D systems). Time-lapse analysis was carried out using a Widefield Leica Thunder-TIRF imager microscope ...
• Divergent phenotypes in germline versus conditional mutant mouse models of Sifrim-Hitz-Weiss Syndrome

  Sarah Larrigan, Shrilaxmi Joshi, Pierre Mattar, bioRxiv - Neuroscience 2023

  Quote: ... goat anti-Sox2 (1:200, R&D Systems AF2018), Rabbit anti-Tbr1 (1:100 ...
• A newly-recognized population of residual neural crest cells in the adult leptomeninges is re-activated for vascular repair

  Yoshihiko Nakamura, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-Bmp7 antibody (1:100, AF354, R&D Systems), anti-Col3a1 antibody (1:100 ...
• Extracellular vesicle-associated cholesterol dictates the regenerative functions of macrophages in the brain

  Sam Vanherle, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-O4 (1:1000, cat. #MAB1326, R&D systems), anti-Olig2 (1:100 ...
• DNMT3A clonal hematopoiesis-driver mutations induce cardiac fibrosis by paracrine activation of fibroblasts

  Mariana Shumliakivska, et al., bioRxiv - Physiology 2023

  Quote: ... goat anti-PDGFRα (1:20, #AF1062, R&D Systems), biotinylated Ulex Europaeus Agglutinin I (1:100 ...
• Extracellular vesicle-associated cholesterol dictates the regenerative functions of macrophages in the brain

  Sam Vanherle, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-Olig2 (1:100, cat. #AF2418, R&D systems), anti-CC1 (1:100 ...
• Gas6 ameliorates intestinal mucosal immunosenescence to prevent the translocation of a gut pathobiont, Klebsiella pneumoniae, to the liver

  Hitoshi Tsugawa, et al., bioRxiv - Microbiology 2023

  Quote: ... 1 μg of anti-Gas6 antibody (R&D Systems), or 1 μg of human recombinant Gas6 protein (R&D Systems ...
• Acquired and intrinsic resistance to vemurafenib in BRAF^V600E-driven melanoma brain metastases

  Ping Zhang, et al., bioRxiv - Pharmacology and Toxicology 2022

  Quote: ... MET (1:100; AF527; R&D Systems; Minneapolis, MN), phospho-IGF1R (1:40,000 ...
• Disease-associated astrocyte epigenetic memory promotes CNS pathology

  Hong-Gyun Lee, et al., bioRxiv - Immunology 2024

  Quote: ... PE anti-O4 (R&D Systems, #FAB1326P, 1:100), PE anti-CD105 (eBioscience ...
• The Notch1/Delta-like-4 axis is crucial for the initiation and progression of oral squamous cell carcinoma

  Christian T. Meisel, et al., bioRxiv - Cancer Biology 2024

  Quote: ... and α-Dll4 (1:100; R&D Systems, AF1389) were used.
• Conserved YKL-40 changes in mice and humans after postoperative delirium

  Jennifer David-Bercholz, et al., bioRxiv - Neuroscience 2022

  Quote: ... goat anti-CD31 (1:500, #AF3628; R&D Systems), rabbit anti-NeuN (1:1000 ...
• Rejection of inappropriate synaptic partners mediated by transcellular FLRT2-UNC5 signaling

  Cameron L. Prigge, et al., bioRxiv - Neuroscience 2022

  Quote: ... goat anti-FLRT2 1:250 (AF2877 R&D Systems); mouse anti-GAD65 1:1000 (MAB351 ...
• GDF15 and ACE2 stratify COVID19 patients according to severity while ACE2 mutations increase infection susceptibility

  Margalida Torrens-Mas, et al., bioRxiv - Molecular Biology 2022

  Quote: ... or anti-ACE2 (1:50; MAB933; R&D Systems) in PBST containing 0,1% BSA ON at 4°C ...
• Targeting the BAG-1 family of co-chaperones in lethal prostate cancer

  Antje Neeb, et al., bioRxiv - Molecular Biology 2022

  Quote: ... panBAG-1 (mouse, goat polyclonal, AF815, R&D systems), and AR-FL (mouse/human ...
• Understanding Lesion Progression in a Chronic Model of Cerebral Cavernous Malformations through Combined MRI and Histology

  Delaney G. Fisher, et al., bioRxiv - Neuroscience 2022

  Quote: ... goat anti-CD31 (1:20, R&D Systems, AF3628), were diluted in the blocking solution and incubated with mounted brain sections overnight at 4°C ...
• Myelin plasticity in ventral tegmental area is required for opioid reward

  Belgin Yalçın, et al., bioRxiv - Neuroscience 2022

  Quote: ... Goat anti-Pdgfra (1:500; R&D Systems, AF1062), rabbit anti-Olig2 (1:500 ...
• Specific targeting of inflammatory osteoclastogenesis by the probiotic yeast S. boulardii CNCM I-745 reduces bone loss in osteoporosis

  Maria-Bernadette Madel, et al., bioRxiv - Physiology 2022

  Quote: ... Dectin-2 (1:100, clone 17611; R&D Systems), TLR2 (1:200 ...
• 16p11.2 locus decelerates subpallial maturation and limits variability in human iPSC-derived ventral telencephalic organoids

  Rana Fetit, et al., bioRxiv - Developmental Biology 2022

  Quote: ... and FGF2 (20 ng ml−1; R&D Systems) until day 24 ...
• Diversity within olfactory sensory derivatives revealed by the contribution of Dbx1 lineages

  Frédéric Causeret, et al., bioRxiv - Developmental Biology 2022

  Quote: ... goat anti-Sox2 (R&D Systems AF2018, 1:100), goat anti-OMP (Wako #019-22291 ...
• The epigenetic modifier DOT1L regulates gene regulatory networks necessary for cardiac patterning and cardiomyocyte cell cycle withdrawal

  Paola Cattaneo, et al., bioRxiv - Developmental Biology 2022

  Quote: ... anti-PDGFR-α (1:200 R&D Systems #AF1062), anti-tdTomato (1:100 Sicgen #ab8181-200) ...
• Selective Translation Orchestrates Key Signaling Pathways in Primed Pluripotency

  Chikako Okubo, et al., bioRxiv - Cell Biology 2024

  Quote: ... goat polyclonal anti-SOX2 (1:40, R&D Systems), goat polyclonal anti-NANOG (1:40 ...
• Selective Translation Orchestrates Key Signaling Pathways in Primed Pluripotency

  Chikako Okubo, et al., bioRxiv - Cell Biology 2024

  Quote: ... goat polyclonal anti-NANOG (1:40, R&D Systems), mouse monoclonal anti-p53 (DO-7 ...
• Repulsive Sema3E-Plexin-D1 signaling coordinates both axonal extension and steering via activating an autoregulatory factor, Mtss1

  Namsuk Kim, et al., bioRxiv - Developmental Biology 2024

  Quote: ... anti-Plexin-D1 (1:1000, AF4160, R&D Systems), anti-β-actin (1:5000 ...
• Repulsive Sema3E-Plexin-D1 signaling coordinates both axonal extension and steering via activating an autoregulatory factor, Mtss1

  Namsuk Kim, et al., bioRxiv - Developmental Biology 2024

  Quote: ... anti-Plexin-D1 (1:1000, AF4160, R&D Systems), and anti-β-Actin (1:5000 ...
• Stably-Inverted Apical-Out Human Upper Airway Organoids for SARS-CoV-2 Infection and Therapeutic Testing

  Ji-Hoon Lee, et al., bioRxiv - Bioengineering 2024

  Quote: goat anti-ACE2 (R&D Systems, AF933; 1:500)
• Selective Translation Orchestrates Key Signaling Pathways in Primed Pluripotency

  Chikako Okubo, et al., bioRxiv - Cell Biology 2024

  Quote: ... goat polyclonal anti-p53 (1:100, R&D Systems), rabbit monoclonal anti-p21 (1:50 ...
• Contributions of mirror-image hair cell orientation to mouse otolith organ and zebrafish neuromast function

  Kazuya Ono, et al., bioRxiv - Neuroscience 2024

  Quote: Goat anti-SPP1 (R&D Systems, AF808, 1:200)
• Rapid turnover of CTLA4 is associated with a complex architecture of reversible ubiquitylation

  Pei Yee Tey, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-USP8 (R&D Systems, AF7735, WB 1:500), anti-USP8 (Bethyl ...
• Chikungunya Virus Release is Reduced by TIM-1 Receptors Through Binding of Envelope Phosphatidylserine

  Judith M. Reyes Ballista, et al., bioRxiv - Microbiology 2024

  Quote: ... or CHIKV E1 (1:1,000, MAB97792, R&D systems).
• Usutu virus and West Nile virus use a transcellular route of neuroinvasion across an in vitro model of the human blood-brain barrier

  Eleanor M. Marshall, Marion Koopmans, Barry Rockx, bioRxiv - Microbiology 2024

  Quote: ... goat anti-VE-Cadherin (1:100, R&D systems), rabbit anti-PDGFRβ (1:200 ...
• Dispensable regulation of brain development and myelination by Serpina3n

  Meina Zhu, et al., bioRxiv - Neuroscience 2024

  Quote: ... cat#3700),Goat anti-SerpinA3N (1:500, R&D Systems, AF7409), Goat anti-Olig2 (1:500 ...
• Atacama Clear for Complex 3D Imaging of Organs

  Neranjan de Silva, et al., bioRxiv - Molecular Biology 2024

  Quote: ... anti-podocalyxin (3169, R&D Systems, at 1:200), anti-HCN4 (APC-052 ...
• L-Type Ca²⁺ channels and TRPC3 channels shape brain pericyte Ca²⁺ signaling and hemodynamics throughout the arteriole to capillary network in vivo

  Jessica Meza-Resillas, et al., bioRxiv - Neuroscience 2024

  Quote: ... goat anti-CD31 (1:200, R&D systems, AF3628), rabbit-anti-Cav1.2 (1:200 ...
• Contributions of mirror-image hair cell orientation to mouse otolith organ and zebrafish neuromast function

  Kazuya Ono, et al., bioRxiv - Neuroscience 2024

  Quote: Goat anti-SOX2 (R&D Systems, AF2018, 1:200)
• Expression of the transcription factor Isl1 in dopaminergic neurons of the mouse forebrain

  Adriana C. Camarano, et al., bioRxiv - Developmental Biology 2023

  Quote: ... goat anti-Isl1 (1:1000; R&D Systems AF1837); mouse anti-Nkx2.2 (1:1000 ...
• Development of Pial Collaterals by Extension of Pre-existing Artery Tips

  Suraj Kumar, et al., bioRxiv - Developmental Biology 2024

  Quote: ... VegfR2 (Catalog number: AF644, R&D Systems, 1:250). All secondary antibodies were procured from Invitrogen and used at a dilution of 1:500.