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1251 - 1300 of 3059 citations for 6 Boc 1 oxa 6 azaspiro 3.3 heptan 3 one since 2019

• Regulation of beta-amyloid production in neurons by astrocyte-derived cholesterol

  Hao Wang, et al., bioRxiv - Neuroscience 2020

  Quote: Human amyloid beta 1-40 (R&D Systems DAB140B) and 1-42 (R&D Systems DAB142 ...
• Time-dependent dual effect of NLRP3 inflammasome in brain ischemia

  Alejandra Palomino-Antolin, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-pro IL-1β (1:1000; R&D Systems), anti-Claudin-5 (1:500 ...
• Single-cell analysis reveals diverse stromal subsets associated with immune evasion in triple-negative breast cancer

  Sunny Z. Wu, et al., bioRxiv - Cancer Biology 2020

  Quote: ... anti-FAP (1:100; R&D Systems #FAB3715P-025) and anti-CD36 (1:100 ...
• The connection between Rap1 and Talin1 in CD4⁺ T Lymphocytes

  Frederic Lagarrigue, et al., bioRxiv - Cell Biology 2021

  Quote: ... Recombinant mouse MAdCAM-1 was from R&D Systems.
• Neurofibromin 1 controls metabolic balance and Notch-dependent quiescence of juvenile myogenic progenitors

  Xiaoyan Wei, et al., bioRxiv - Cell Biology 2021

  Quote: ... Goat anti-Desmin (R&D Systems # AF3844; 1:500), Anti-trimethyl-Histone H3 (Lys27 ...
• BSG/CD147 and ACE2 receptors facilitate SARS-CoV-2 infection of human iPS cell-derived kidney podocytes

  Titilola D. Kalejaiye, et al., bioRxiv - Bioengineering 2021

  Quote: ... Human TRA-1-85/CD147 (R&D systems, MAB3195), Cathepsin L (Santa Cruz Biotechnology ...
• Soft, dynamic hydrogel confinement improves kidney organoid lumen morphology and reduces epithelial–mesenchymal transition in culture

  Floor A.A. Ruiter, et al., bioRxiv - Bioengineering 2021

  Quote: ... and FGF-9 (200 ng·ml-1, R&D Systems). By day 7 ...
• Salmonella exploits OmpR to switch essential morphogenetic peptidoglycan synthases in response to intracellular cues

  David López-Escarpa, et al., bioRxiv - Microbiology 2021

  Quote: ... mouse monoclonal anti-6xHis (1:2500; R&D Systems), rabbit polyclonal anti-PBP2 (1:1000 ...
• Inhibiting proBDNF to mature BDNF conversion leads to autism-like phenotypes in vivo

  He You, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-SorCS2 (1:500; R&D Systems, Minneapolis, MN), anti-SorCS3 (1:500 ...
• SARS-CoV-2 infects brain choroid plexus and disrupts the blood-CSF-barrier

  Laura Pellegrini, et al., bioRxiv - Neuroscience 2020

  Quote: ... sheep anti-Tbr2 (1:200, R&D Systems, AF6166), rat anti-CTIP2 (1:300 ...
• Presynaptic inhibition of cutaneous afferents prevents self-generated itch

  Augusto Escalante, Rüdiger Klein, bioRxiv - Neuroscience 2020

  Quote: ... goat anti-TrkC (1:500) (AF1404, R&D Systems), sheep anti-TH (1:1000 ...
• A CRISPR/Cas9 genetically engineered organoid biobank reveals essential host factors for coronaviruses

  Joep Beumer, et al., bioRxiv - Molecular Biology 2021

  Quote: ... goat anti-ACE (1:100; R&D Systems, AF933), goat anti-DPP-4 (1:200 ...
• Stable Flow-induced Expression of KLK10 Inhibits Endothelial Inflammation and Atherosclerosis

  Darian Williams, et al., bioRxiv - Cell Biology 2021

  Quote: ... and anti-HTRA1 (R&D Systems MAB2916, 1:1000) ( overnight at 4°C in 5% milk in TBST at the concentration recommended by the manufacturer ...
• Human iPSC-derived brain endothelial microvessels in a multi-well format enable permeability screens of anti-inflammatory drugs

  Sven Fengler, et al., bioRxiv - Cell Biology 2021

  Quote: ... monoclonal anti-interleukin-1 beta antibody (R&D systems) was used.
• Extracellular vesicle fusion visualized by cryo-EM

  Mattia I. Morandi, et al., bioRxiv - Biophysics 2022

  Quote: ... anti-PTGFRN (1:1000, R&D Systems, MAB10043-100), anti-CD63 (1:1000 ...
• Mechanisms Underlying WNT-mediated Priming of Human Embryonic Stem Cells

  Anna Yoney, et al., bioRxiv - Developmental Biology 2022

  Quote: ... BRACHYURY (rabbit monoclonal, R&D Systems MAB20851, 1:400), EOMES (mouse monoclonal ...
• Mechanisms Underlying WNT-mediated Priming of Human Embryonic Stem Cells

  Anna Yoney, et al., bioRxiv - Developmental Biology 2022

  Quote: ... EOMES (mouse monoclonal, R&D Systems MAB6166, 1:400), GSC (goat polyclonal ...
• Mechanisms Underlying WNT-mediated Priming of Human Embryonic Stem Cells

  Anna Yoney, et al., bioRxiv - Developmental Biology 2022

  Quote: ... BRACHYURY (goat polyclonal, R&D Systems AF2085, 1:150), BRACHYURY (rabbit monoclonal ...
• Genetically-Modified Macrophages Accelerate Myelin Repair

  Marie-Stephane Aigrot, et al., bioRxiv - Neuroscience 2022

  Quote: ... rat anti-Sema3F (R&D Systems, MAB3237, 1:50); rabbit anti-P2Y12 (Anaspec ...
• An essential function for autocrine Hedgehog signaling in epithelial proliferation and differentiation in the trachea

  Wenguang Yin, et al., bioRxiv - Developmental Biology 2022

  Quote: ... Rat anti-SCGB3A1 (1:200, R&D Systems, MAB2954); Rat anti-SCGB3A2 (1:200 ...
• An essential function for autocrine Hedgehog signaling in epithelial proliferation and differentiation in the trachea

  Wenguang Yin, et al., bioRxiv - Developmental Biology 2022

  Quote: ... Rat anti-SCGB3A2 (1:200, R&D Systems, MAB3465); Rabbit anti-Ki67 (1:400 ...
• An essential function for autocrine Hedgehog signaling in epithelial proliferation and differentiation in the trachea

  Wenguang Yin, et al., bioRxiv - Developmental Biology 2022

  Quote: ... Goat anti-SOX9 (1:500, R&D Systems, AF3075); Rat anti-Cd140a (1:100 ...
• Mechanisms Underlying WNT-mediated Priming of Human Embryonic Stem Cells

  Anna Yoney, et al., bioRxiv - Developmental Biology 2022

  Quote: ... GSC (goat polyclonal, R&D Systems AF4086, 1:200). Cells were incubated with secondary antibodies (diluted 1:1000) ...
• Oligodendrocyte-lineage cell exocytosis and L-type prostaglandin D synthase promote oligodendrocyte development and myelination

  Lin Pan, et al., bioRxiv - Neuroscience 2022

  Quote: ... PDGFRα (R&D Systems, cat #AF1062, dilution 1:500), Olig2 (Millipore ...
• Systematic Single Cell Pathway Analysis (SCPA) reveals novel pathways engaged during early T cell activation

  Jack A. Bibby, et al., bioRxiv - Immunology 2022

  Quote: ... anti-sheep IgG-NL557 (R&D Systems, 1:500). IFNγ expression was analyzed using the IFN-γ Secretion Assay (PE ...
• Mild respiratory SARS-CoV-2 infection can cause multi-lineage cellular dysregulation and myelin loss in the brain

  Anthony Fernández-Castañeda, et al., bioRxiv - Neuroscience 2022

  Quote: ... goat anti-PDGFRa (1:500; R&D Systems AF1062), mouse anti-CC1 (1:100 ...
• Lesion environments direct transplanted neural progenitors towards a wound repair astroglial phenotype

  T.M. O’Shea, et al., bioRxiv - Neuroscience 2022

  Quote: ... rat anti-Vimentin (1:500; R&D Systems, MAB2105); rat anti-Cd44 (IM7 ...
• Lesion environments direct transplanted neural progenitors towards a wound repair astroglial phenotype

  T.M. O’Shea, et al., bioRxiv - Neuroscience 2022

  Quote: ... goat anti-Sox9 (1:1000, R&D systems, AF3075); goat anti-Dppa4 (1:2000 ...
• Lesion environments direct transplanted neural progenitors towards a wound repair astroglial phenotype

  T.M. O’Shea, et al., bioRxiv - Neuroscience 2022

  Quote: ... goat anti-Dppa4 (1:200; R&D Systems, AF3730), Rabbit anti-Id3 (1:200 ...
• Lesion environments direct transplanted neural progenitors towards a wound repair astroglial phenotype

  T.M. O’Shea, et al., bioRxiv - Neuroscience 2022

  Quote: ... goat anti-Cd13 (1:200, R&D systems, AF2335); rat anti-Galectin-3 (1:200 ...
• Lesion environments direct transplanted neural progenitors towards a wound repair astroglial phenotype

  T.M. O’Shea, et al., bioRxiv - Neuroscience 2022

  Quote: ... goat anti-Nestin (1:2000, R&D Systems, AF2736); rabbit alpha-smooth muscle actin (α-Sma ...
• Lesion environments direct transplanted neural progenitors towards a wound repair astroglial phenotype

  T.M. O’Shea, et al., bioRxiv - Neuroscience 2022

  Quote: ... goat anti-Sox9 (1:500, R&D systems, AF3075); rabbit Aldh1l1 (1:1000 ...
• Lesion environments direct transplanted neural progenitors towards a wound repair astroglial phenotype

  T.M. O’Shea, et al., bioRxiv - Neuroscience 2022

  Quote: ... goat anti-Oct4 (1:500, R&D systems, AF1759); goat anti-Sox9 (1:500 ...
• Reactive astrocytes transduce blood-brain barrier dysfunction through a TNFα-STAT3 signaling axis and secretion of alpha 1-antichymotrypsin

  Hyosung Kim, et al., bioRxiv - Neuroscience 2022

  Quote: ... E-Selectin (AF724, R&D systems, 1:1000 dilution), and GAPDH (D16H11 ...
• Combined single-cell RNA-seq profiling and enhancer editing reveals critical spatiotemporal controls over thalamic nuclei formation in the murine embryo

  Kiya W. Govek, et al., bioRxiv - Neuroscience 2022

  Quote: ... mouse anti- Sox2 (1:100, R&D Systems, MAB2018), rabbit anti-Sox2 (1:300 ...
• Long-term functional regeneration of radiation-damaged salivary glands through delivery of a neurogenic hydrogel

  Jianlong Li, et al., bioRxiv - Cell Biology 2022

  Quote: ... goat anti-GFRα2 (1:200; R&D Systems AF429); and vasoactive intestinal peptide antibody anti-VIP (1:100 ...
• Molecular insights into intrinsic transducer-coupling bias in the CXCR4-CXCR7 system

  Parishmita Sarma, et al., bioRxiv - Biochemistry 2022

  Quote: ... 100 ng ml-1 CXCL12-α (R&D Systems) and/or 100 nM VUF11207 (Cayman Chemical ...
• Ectopic insert-dependent neuronal expression of GFAP promoter-driven AAV constructs in adult mouse retina

  Nguyet Le, et al., bioRxiv - Neuroscience 2022

  Quote: ... Goat anti-Otx2 (R&D Systems, #AF1979, 1:200), Rabbit anti-Rbpms (ThermoFisher ...
• A fluorescent perilipin 2 knock-in mouse model visualizes lipid droplets in the developing and adult brain

  Sofia Madsen, et al., bioRxiv - Cell Biology 2022

  Quote: ... SOX2 goat (1:500, R&D Systems AF2018-SP), tdTomato goat (1:500 ...
• Cell type-specific isolation and transcriptomic profiling informs glial pathology in human temporal lobe epilepsy

  Jessica Tome-Garcia, et al., bioRxiv - Neuroscience 2020

  Quote: ... 1:250 goat anti-hOLIG2 (R&D Systems, AF2418SP); 1:250 rabbit anti-Ki67 (Abcam ...
• Ventricular, atrial and outflow tract heart progenitors arise from spatially and molecularly distinct regions of the primitive streak

  Kenzo Ivanovitch, et al., bioRxiv - Developmental Biology 2021

  Quote: ... goat anti-T (1:250, R&D Systems AF2085), rabbit anti-FOXA2 (1:250 ...
• Adaptive tail-length evolution in deer mice is associated with differential Hoxd13 expression in early development

  Evan P. Kingsley, et al., bioRxiv - Genetics 2021

  Quote: ... anti-Brachyury/T (R&D Systems AF2085; 1:500) and fluorophore-conjugated secondary antibodies (anti-mouse-AlexaFluor555 and anti-goat-AlexaFluor488 ...
• Maladaptive myelination promotes epileptogenesis in absence epilepsy

  Juliet K. Knowles, et al., bioRxiv - Neuroscience 2020

  Quote: ... Goat anti-PDGFRα (1:200, R&D Systems AF1062), mouse anti-APC (CC1,1:50 ...
• Fibrillar Aβ causes profound microglial metabolic perturbations in a novel APP knock-in mouse model

  Dan Xia, et al., bioRxiv - Neuroscience 2021

  Quote: ... goat-anti-CD31 (R&D Systems, AF3628, 1:500), mouse-anti-alpha smooth muscle actin Cy3 (Sigma ...
• Adult Neurogenesis in Peripheral Nervous System

  Yisheng Liu, Xiaosong Gu, bioRxiv - Neuroscience 2020

  Quote: ... plexin C1 mouse 1:500 (R&D Systems AF5375), SSEA-1 mouse 1:200 (Millipore [clone MC-480] MAB4301) ...
• After traumatic brain injury oligodendrocytes regain a plastic phenotype and can become astrocytes

  Xianshu Bai, et al., bioRxiv - Neuroscience 2021

  Quote: ... anti-Sox10 (1:100, R&D Systems, Minneapolis, USA); polyclonal rabbit ...
• After traumatic brain injury oligodendrocytes regain a plastic phenotype and can become astrocytes

  Xianshu Bai, et al., bioRxiv - Neuroscience 2021

  Quote: ... anti-Sox2 (1:200, R&D Systems, Minneapolis, USA), anti-DsRed (1:1000 ...
• Targeted attenuation of elevated histone marks at SNCA alleviates α-synuclein in Parkinson’s disease

  Subhrangshu Guhathakurta, et al., bioRxiv - Neuroscience 2020

  Quote: ... 1 ng/ml TGFb3(R&D Systems, 243B3002/CF), and 0.1 mM dibutyryl cAMP (Sigma ...
• Developmental HCN channelopathy results in decreased neural progenitor proliferation and microcephaly in mice

  Anna Katharina Schlusche, et al., bioRxiv - Neuroscience 2021

  Quote: Rat NSCs (NSC001, R&D systems, P#0-1) were plated on 35-mm dishes (µ-Dish 35mm ...
• Dysregulation of NRSF/REST via EHMT1 is associated with psychiatric disorders

  Mouhamed Alsaqati, et al., bioRxiv - Neuroscience 2021

  Quote: ... MAP2 (1:750) (MAB8304, R&D Systems, Minneapolis, MN) or Caspease-3 (1:500 ...