Labshake search

1551 - 1600 of 3059 citations for 6 Boc 1 oxa 6 azaspiro 3.3 heptan 3 one since 2019

• The connection between Rap1 and Talin1 in CD4⁺ T Lymphocytes

  Frederic Lagarrigue, et al., bioRxiv - Cell Biology 2021

  Quote: ... Recombinant mouse VCAM-1-Fc was from R&D Systems. Recombinant mouse ICAM-1 and VCAM-1-Fc were from BioLegend ...
• mTOR controls neurotoxic lysosome exocytosis in inflammatory reactive astrocytes

  Brendan Rooney, et al., bioRxiv - Cell Biology 2021

  Quote: ... CTSD (1 ug/mL, R&D Systems cat. no. AF1014), β-actin (1:1000 ...
• The 14-3-3 Proteins Bmh1 and Bmh2 Are Key Regulators of Meiotic Commitment

  Janardan N. Gavade, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-goat IgG HRP (R&D Systems, HAF109, 1:5000).
• The role of muscle stem cells and fibro-adipogenic progenitors in female pelvic floor muscle regeneration following birth injury

  Francesca Boscolo Sesillo, et al., bioRxiv - Cell Biology 2021

  Quote: ... goat anti-PDGFR-α (R&D Systems, AF1062, 1:100), α-SMA (Cell Signaling ...
• Axon-dependent expression of YAP/TAZ mediates Schwann cell remyelination but not proliferation after nerve injury

  Matthew Grove, et al., bioRxiv - Neuroscience 2020

  Quote: ... goat anti-Sox10 (R&D Systems #AF-2864; 1:100), goat anti-p75 (Neuromics #GT15057 ...
• Epigenetic modulation reveals differentiation state specificity of oncogene addiction

  Mehwish Khaliq, et al., bioRxiv - Systems Biology 2021

  Quote: ... AXL (goat pAb, R&D Systems, Cat# AF154, 1:400), p-RbS807/811 (goat pAb ...
• The human brain vasculature shows a distinct expression pattern of SARS-CoV-2 entry factors

  Moheb Ghobrial, et al., bioRxiv - Neuroscience 2020

  Quote: ... goat pAB anti-PDGFRβ (1:100, R&D Systems, #AF385). Briefly ...
• The Sez6 family inhibits complement at the level of the C3 convertase

  Wen Q. Qiu, et al., bioRxiv - Neuroscience 2020

  Quote: ... polyclonal sheep anti-Sez6L2 (R&D Systems, AF4916; 1:2000), monoclonal mouse anti-myc ((Developmental Studies Hybridoma Bank ...
• SARS-CoV-2 infection induces inflammatory bone loss in golden Syrian hamsters

  Wei Qiao, et al., bioRxiv - Microbiology 2021

  Quote: ... and 1 ng/mL IFN-γ (R&D system, USA).
• Lung-selective Cas13d-based nanotherapy inhibits lethal SARS-CoV-2 infection by targeting host protease Ctsl

  Zhifen Cui, et al., bioRxiv - Microbiology 2021

  Quote: ... Antibodies targeting the CTSL (R&D SYSTEMS, #AF1515, 1:800) and the SARS-CoV-2 nucleoprotein (N ...
• A CRISPR/Cas9 genetically engineered organoid biobank reveals essential host factors for coronaviruses

  Joep Beumer, et al., bioRxiv - Molecular Biology 2021

  Quote: ... goat anti-DPP-4 (1:200; R&D systems, AF1180) and rabbit anti-MERS S1 (1:200 ...
• Conserved Transcription Factors Control Chromatin Accessibility and Gene Expression to Maintain Cell Fate Stability and Restrict Reprogramming of Differentiated Cells

  Maria A. Missinato, et al., bioRxiv - Cell Biology 2021

  Quote: ... and mouse anti-TUJ1 (R&D Systems, MAB1195, 1:200); rabbit anti-NANOG (Abcam ...
• Endothelial cells elicit a pro-inflammatory response to SARS-CoV-2 without productive viral infection

  Lilian Schimmel, et al., bioRxiv - Cell Biology 2021

  Quote: ... goat anti-ACE2 (R&D systems, AF933, WB 1:1000), mouse anti-dsRNA (Millipore ...
• Frizzled BRET sensors based on bioorthogonal labeling of unnatural amino acids reveal WNT-induced dynamics of the cysteine-rich domain

  Maria Kowalski-Jahn, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-Nluc (R&D systems, MAB100261-SP, mouse, 1:500) and GAPDH (Cell Signaling Technology ...
• Microglial P2X4 receptors promote ApoE degradation and cognitive deficits in Alzheimer disease

  Jennifer Hua, et al., bioRxiv - Neuroscience 2022

  Quote: ... donkey anti-rabbit-A557 (1:2000, R&D systems NL004), goat anti-rabbit-A488 (1:2000 ...
• Microglial P2X4 receptors promote ApoE degradation and cognitive deficits in Alzheimer disease

  Jennifer Hua, et al., bioRxiv - Neuroscience 2022

  Quote: ... goat anti-Cathepsin B (1:1000, R&D systems AF965), rabbit anti-P2X4 (1:200 ...
• 3D-imaging reveals conserved cerebrospinal fluid drainage via meningeal lymphatic vasculature in mice and humans

  Laurent Jacob, et al., bioRxiv - Neuroscience 2022

  Quote: ... Goat anti– human PROX1 (AF2727; R&D Systems;1:1000), Rabbit anti-mouse TUJ1 (802001 ...
• Semaphorin 3C exacerbates liver fibrosis

  Francesca De Angelis Rigotti, et al., bioRxiv - Pathology 2022

  Quote: ... anti-NRP2 (1:1000, R&D Systems, Cat. No. AF567), anti-VCP (1:2000 ...
• Mechano-redox control of Mac-1 de-adhesion from ICAM-1 by protein disulfide isomerase promotes directional movement of neutrophils under flow

  Alexander Dupuy, et al., bioRxiv - Biochemistry 2022

  Quote: ... 2 µg of recombinant Mac-1 integrin (R&D systems) was incubated with reduced PDI or enzymatically inactive PDI at 10 µM for 30 min at 25°C ...
• Autism-associated mutation in Hevin/Sparcl1 induces endoplasmic reticulum stress through structural instability

  Takumi Taketomi, et al., bioRxiv - Molecular Biology 2022

  Quote: ... goat anti-Hevin (1:500, R&D Systems, Cat# AF2836), and mouse anti-GM130 (1:500 ...
• NF-κB memory coordinates transcriptional responses to dynamic inflammatory stimuli

  Andrew G. Wang, et al., bioRxiv - Systems Biology 2022

  Quote: ... mouse interleukin 1 beta (IL-1β; R&D Systems, 401ML010CF), ultrapure lipopolysaccharide (LPS ...
• Lesion environments direct transplanted neural progenitors towards a wound repair astroglial phenotype

  T.M. O’Shea, et al., bioRxiv - Neuroscience 2022

  Quote: ... goat anti-Nanog (1:1000, AF2729-SP R&D Systems); rabbit anti-Oct4 (1:1000 ...
• Lesion environments direct transplanted neural progenitors towards a wound repair astroglial phenotype

  T.M. O’Shea, et al., bioRxiv - Neuroscience 2022

  Quote: ... goat anti-Pdgfr-α (1:500, R&D systems, AF1062); goat anti-Nestin (1:500 ...
• Lesion environments direct transplanted neural progenitors towards a wound repair astroglial phenotype

  T.M. O’Shea, et al., bioRxiv - Neuroscience 2022

  Quote: ... goat anti-Clusterin (Clu) (1:200, R&D systems, AF2747); Rabbit anti-Tuj-1 (1:500 ...
• Reactive astrocytes transduce blood-brain barrier dysfunction through a TNFα-STAT3 signaling axis and secretion of alpha 1-antichymotrypsin

  Hyosung Kim, et al., bioRxiv - Neuroscience 2022

  Quote: ... mouse anti-Glut1 (1:1000 dilution, FAB1418G, R&D systems), mouse anti-occludin (1:500 dilution ...
• The lipid raft-associated protein stomatin is required for accumulation of dectin-1 in the phagosomal membrane and for full activity of macrophages against Aspergillus fumigatus

  Marie Goldmann, et al., bioRxiv - Microbiology 2022

  Quote: ... or goat anti-dectin-1/CLEC7 (AF1756, R&D Systems) were used with a concentration of 1:500 (Stomatin ...
• Phosphatidylserine within the Viral Membrane Enhances Chikungunya Virus Infectivity in a Cell-type Dependent Manner

  Kerri L. Miazgowicz, et al., bioRxiv - Microbiology 2022

  Quote: ... or α - AXL antibody (1:100, AF154, R&D Systems) and incubated at 4°C and gently shook for 1 hr ...
• Arginine 65 methylation of Neurogenin 3 by PRMT1 is a prerequisite for development of hESCs into pancreatic endocrine cells

  Gahyang Cho, et al., bioRxiv - Developmental Biology 2022

  Quote: ... mouse anti-pancreatic polypeptide (PPY, 1:200, R&D Systems), and rabbit anti-somatostatin (SST ...
• Optimized transcriptional signature for evaluation of MEK/ERK pathway baseline activity and long-term modulations in ovarian cancer

  Mikhail S. Chesnokov, Anil Yadav, Ilana Chefetz, bioRxiv - Cancer Biology 2022

  Quote: ... pp90RSK1 (R&D Systems, Minneapolis, MN, USA, 1024A, 1:1000), GAPDH (ProteinTech ...
• Street RABV induces the cholinergic anti-inflammatory pathway in human monocyte-derived macrophages by binding to nAChr ɑ7, and upregulates the M2-c marker CD163

  C.W.E. Embregts, et al., bioRxiv - Immunology 2021

  Quote: ... or with IL-1 (20 ng/mL R&D Systems), to induce the M1 ...
• Boosting L-type Ca²⁺ channel activity in tuberous sclerosis mitigates excess glutamate receptors

  Farr Niere, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-phospho-GluA1 (Ser845, 1:1000, R&D Systems), mouse anti-GluA1 (1:2000 ...
• Anthrax Toxin as a Molecular Platform to Target Nociceptive Neurons and Modulate Pain

  Nicole J. Yang, et al., bioRxiv - Neuroscience 2020

  Quote: ... goat polyclonal anti-TRPV1 (R&D Systems, #AF3066, 1:500), highly cross-adsorbed Alexa 647 ...
• After traumatic brain injury oligodendrocytes regain a plastic phenotype and can become astrocytes

  Xianshu Bai, et al., bioRxiv - Neuroscience 2021

  Quote: ... and anti-PDGFRα (1:500, R&D Systems, Minneapolis, USA), anti-Sox10 (1:100 ...
• AraC binds the p75^NTR transmembrane domain to induce neurodegeneration in mature neurons

  Vanessa Lopes-Rodrigues, et al., bioRxiv - Cell Biology 2021

  Quote: ... goat anti-TrkB (R&D systems, Cat: AF1494, 1:500), rabbit anti-IκBα (Santa Cruz ...
• CRISPR-Cas9 mediated nuclear transport and genomic integration of nanostructured genes in human primary cells

  Enrique Lin-Shiao, et al., bioRxiv - Bioengineering 2021

  Quote: ... and 10 U mL−1 IL-15 (R&D Systems) for 48 hours in complete XVivo15 medium (Lonza ...
• A disynaptic circuit in the globus pallidus controls locomotion inhibition

  Asier Aristieta, et al., bioRxiv - Neuroscience 2020

  Quote: ... or streptavidine-557 (1/1000; Cat# NL999, R&D system). Additional staining was performed as for the in vivo histology (see above) ...
• PRMT5 is a therapeutic target in choroidal neovascularization

  Anbukkarasi Muniyandi, et al., bioRxiv - Pharmacology and Toxicology 2022

  Quote: ... and rabbit IgG control (1:100 dilution; R&D systems, Minneapolis ...
• Polar protein Wag31 both activates and inhibits cell wall metabolism at the poles and septum

  Neda Habibi Arejan, et al., bioRxiv - Microbiology 2022

  Quote: ... then stained with 1 μg/mL NADA (R&D systems) for 2 minutes at room temperature ...
• Cardiac fibroblasts regulate cardiomyocyte hypertrophy through dynamic regulation of type I collagen

  Qinghang Meng, et al., bioRxiv - Cell Biology 2022

  Quote: ... PDGFRα from (R&D Systems AF1062; 1:1000 for IF); collagen 1a2 (Santa Cruz sc-393573 ...
• Targeted protein degradation reveals BET bromodomains as the cellular target of Hedgehog Pathway Inhibitor-1

  Meropi Bagka, et al., bioRxiv - Cell Biology 2022

  Quote: ... 1:500 Goat anti-mouse GLI3 (R&D systems, AF3690)) overnight at 4 C ...
• Targeted protein degradation reveals BET bromodomains as the cellular target of Hedgehog Pathway Inhibitor-1

  Meropi Bagka, et al., bioRxiv - Cell Biology 2022

  Quote: ... 1:500 Goat anti-mouse GLI2 (R&D systems, AF3635), 1:500 Goat anti-mouse GLI3 (R&D systems ...
• Epithelial Plasticity and Innate Immune Activation Promote Lung Tissue Remodeling following Respiratory Viral Infection

  Andrew K. Beppu, et al., bioRxiv - Cell Biology 2022

  Quote: ... Goat Polyclonal UGRP1/SCGB3A2 (1:1000, R&D Systems, AF3465); Syrian hamster Monoclonal anti-Pdpn (1:1000 ...
• Genetic Interplay Between Transcription Factor Pou4f1/Brn3a and Neurotrophin Receptor Ret In Retinal Ganglion Cell Type Specification

  Vladimir Vladimirovich Muzyka, et al., bioRxiv - Developmental Biology 2020

  Quote: ... 1:40 goat polyclonal anti-TrkC (R&D Systems, AF1404); 1:20 goat polyclonal anti-GFRα1 (R&D Systems ...
• Genetic Interplay Between Transcription Factor Pou4f1/Brn3a and Neurotrophin Receptor Ret In Retinal Ganglion Cell Type Specification

  Vladimir Vladimirovich Muzyka, et al., bioRxiv - Developmental Biology 2020

  Quote: ... 1:100 goat polyclonal anti-GFRα2 (R&D Systems, AF429); 1:40 goat polyclonal anti-GFRα3 (R&D Systems ...
• Genetic Interplay Between Transcription Factor Pou4f1/Brn3a and Neurotrophin Receptor Ret In Retinal Ganglion Cell Type Specification

  Vladimir Vladimirovich Muzyka, et al., bioRxiv - Developmental Biology 2020

  Quote: ... 1:40 goat polyclonal anti-GFRα3 (R&D Systems, AF2645); 1:1000 chicken anti-GFP (used for detection of CFP protein ...
• LSD1-mediated enhancer silencing enables endocrine cell development through attenuation of retinoic acid signalling

  Nicholas K. Vinckier, et al., bioRxiv - Developmental Biology 2019

  Quote: ... goat anti-osteopontin (Opn) (1:300 dilution, R&D systems); goat anti-PDX1 (1:500 dilution ...
• Cholesterol deprivation induces TGFβ signaling to promote basal differentiation in pancreatic cancer

  Linara G. Cornell, et al., bioRxiv - Cancer Biology 2019

  Quote: ... complemented with Sample Activation Kit 1 (#DY010, R&D systems) and DuoSet ELISA Ancillary Reagent Kit 1 (#DY007 ...
• Polycomb Repressive Complex 2-controlled Essrg regulates intestinal Microfold cell differentiation

  Joel Johnson George, et al., bioRxiv - Molecular Biology 2020

  Quote: ... recombinant mouse R-spondin1 (1 μg/mL; R&D Systems). Media were changed every 2 days ...
• Enhanced Production of Mesencephalic Dopaminergic Neurons from Lineage-Restricted Human Undifferentiated Stem Cells

  Muyesier Maimaitili, et al., bioRxiv - Neuroscience 2021

  Quote: ... sheep anti-hCOL1A1 (1:200, R&D Systems, cat# AF6220), and mouse anti-HNA (1:200 ...
• Formation of multinucleated globoid cells in Krabbe iPSC-derived microglia cultures: a preliminary investigation

  Richard Lieberman, et al., bioRxiv - Neuroscience 2021

  Quote: ... 1 nM or 10 nM rhGALC protein (R&D Systems) was added to the microglia medium at the time of seeding into the assay plate.