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4901 - 4950 of 8510 citations for 6 Chloro 2 3 diphenylimidazo 1 2 b pyridazine since 2019

• High-throughput generation and phenotypic characterization of zebrafish CRISPR mutants of DNA repair genes

  Unbeom Shin, et al., bioRxiv - Developmental Biology 2020

  Quote: ... anti-PCNA (PC10) (Santa Cruz Biotechnology, sc-56, 1:2000), anti-histone H3 (upstate 07-690 ...
• Intestinal ferritinophagy is regulated by HIF-2α and is essential for systemic iron homeostasis

  Nupur K Das, et al., bioRxiv - Physiology 2020

  Quote: ... sc-30968 goat antibody at 1:200 (Santa Cruz Biotechnology); ferritin rabbit antibody at 1:1000 (Cell Signaling Technology) ...
• Early-life hypoxia alters adult physiology and reduces stress resistance and lifespan in Drosophila

  Danielle M Polan, et al., bioRxiv - Physiology 2020

  Quote: ... and anti-actin (1:1000, Santa Cruz Biotechnology, # sc-8432). Secondary antibodies were purchased from Santa Cruz Biotechnology (sc-2030 ...
• Sub-centrosomal mapping identifies augmin-γTuRC as part of a centriole-stabilizing scaffold

  Nina Schweizer, et al., bioRxiv - Cell Biology 2020

  Quote: ... mouse anti-ARL13B (sc-515784, Santa Cruz; IF, 1:100), rabbit anti-CEP192 24 (ExM ...
• Intraflagellar transport complex B proteins regulate the Hippo effector Yap1 during cardiogenesis

  Marina Peralta, et al., bioRxiv - Developmental Biology 2019

  Quote: ... Primary antibodies against Tbx18 (Santa Cruz sc-17869, 1:100), Wt1 (Santa Cruz sc-192 ...
• The Polycomb group protein Ring1 regulates dorsoventral patterning of the mouse telencephalon

  Hikaru Eto, et al., bioRxiv - Developmental Biology 2019

  Quote: ... goat antibodies to Neurog1 (Santa Cruz, sc-19231, 1:200) and rabbit antibodies to H2AK119ub (Cell Signaling Technology ...
• Acetylation-mediated phase control of the nucleolus regulates cellular acetyl-CoA responses

  Ryan Houston, et al., bioRxiv - Cell Biology 2020

  Quote: MDM2 (SMP14) Mouse mAb (1:1000, Santa Cruz, sc-965)
• YB-1 IS REQUIRED FOR THE GENESIS AND METASTATIC CAPACITY OF HUMAN BREAST CANCER

  Sylvain Lefort, et al., bioRxiv - Cancer Biology 2020

  Quote: ... such as anti-ACTIN (Santa Cruz, sc-1615, 1/10,000), anti-H3 (Cell Signaling Technology ...
• Enhancer transcription identifies cis-regulatory elements for photoreceptor cell types

  Rangarajan D. Nadadur, et al., bioRxiv - Molecular Biology 2019

  Quote: ... mouse anti-Rxrg (1:300, Santa Cruz Biotechnology, sc-514134). Secondary antibodies were from Jackson Immunoresearch.
• SARS-CoV-2 binding to ACE2 triggers pericyte-mediated angiotensin-evoked cerebral capillary constriction

  Chanawee Hirunpattarasilp, et al., bioRxiv - Neuroscience 2021

  Quote: ... and rabbit anti-PDGFRβ (Santa Cruz, sc-432, 1:200). Secondary antibodies used were Alexa fluor 488 donkey anti-goat (Invitrogen ...
• A conserved ubiquitin- and ESCRT-dependent pathway to regulate human lysosomal membrane proteins

  Weichao Zhang, et al., bioRxiv - Cell Biology 2020

  Quote: ... mouse anti-HRS (1:500, C-7, Santa Cruz Biotechnology), mouse anti-HA (1:1000 ...
• A conserved ubiquitin- and ESCRT-dependent pathway to regulate human lysosomal membrane proteins

  Weichao Zhang, et al., bioRxiv - Cell Biology 2020

  Quote: ... mouse anti-Vps22 (1:500, C-11, Santa Cruz Biotechnology), mouse anti-HRS (1:500 ...
• A conserved ubiquitin- and ESCRT-dependent pathway to regulate human lysosomal membrane proteins

  Weichao Zhang, et al., bioRxiv - Cell Biology 2020

  Quote: ... mouse-anti-EEA (1:500, G-4, Santa Cruz Biotechnology), rabbit-GAPDH (1:2000 ...
• Lipidomic Profiling Reveals an Age-Related Deficiency of Skeletal Muscle Proresolving Mediators that Contributes to Maladaptive Tissue Remodeling

  James F. Markworth, et al., bioRxiv - Immunology 2020

  Quote: ... and rabbit polyclonal CD163 (Santa Cruz, sc-33560, 1:50). The following day ...
• Mechanistic dissection of global proteomic changes in rats with heart failure and preserved ejection fraction

  Daniel Soetkamp, et al., bioRxiv - Molecular Biology 2021

  Quote: ... or 1 µm Rottlerin (PKC δ inhibitor, Santa Cruz Biotechnology) or buffer (control).
• Klebsiella pneumoniae hijacks the Toll-IL-1R protein SARM1 in a type I IFN-dependent manner to antagonize host immunity

  Claudia Feriotti, et al., bioRxiv - Microbiology 2021

  Quote: ... anti-AIM2 (anti-rabbit, 1:1000; sc- 515895, Santa Cruz), anti-NLRP3 (anti-mouse ...
• Bat influenza vectored NS1-truncated live vaccine protects pigs against heterologous virus challenge

  Jinhwa Lee, et al., bioRxiv - Microbiology 2020

  Quote: ... or anti-β-actin antibody (diluted 1:500, Santa Cruz) overnight at 4ºC ...
• Robust three-dimensional expansion of human adult alveolar stem cells and SARS-CoV-2 infection

  Jeonghwan Youk, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-HOPX (1:200, Santa Cruz Biotechnologies, sc-30216), and sheep anti-PDPN (1:200 ...
• A single-cell transcriptomic atlas of the adult Drosophila ventral nerve cord

  Aaron M. Allen, et al., bioRxiv - Neuroscience 2019

  Quote: ... and anti-AbdA (1:100, C-11 Santa Cruz Biotechnology). Secondary antibodies used included ...
• Discovery of Alstrom syndrome gene as a regulator of centrosome duplication in asymmetrically dividing stem cells in Drosophila

  Cuie Chen, Yukiko M. Yamashita, bioRxiv - Developmental Biology 2019

  Quote: ... rabbit anti-Vasa (d-26; 1:200; Santa Cruz Biotechnology); rabbit anti-Asl (1:2000 ...
• Sox2 modulation increases naïve pluripotency plasticity

  Kathryn Tremble, et al., bioRxiv - Developmental Biology 2020

  Quote: ... mouse monoclonal against Oct4 (1:100, Santa Cruz, sc-5279). Secondary antibodies were Alexa Fluor antibodies (ThermoFisher Scientific ...
• Surface topography is a context-dependent activator of TGF-β signaling in mesenchymal stem cells

  Steven Vermeulen, et al., bioRxiv - Cell Biology 2020

  Quote: ... and anti-SRF antibody (1:200; Santa Cruz; sc-335).
• The Pax6 master control gene initiates spontaneous retinal development via a self-organising Turing network

  Timothy Grocott, et al., bioRxiv - Developmental Biology 2019

  Quote: ... Primary antibody against HSC70 (Santa Cruz sc-7298; 1:2,500) was applied at 4°C overnight and secondary polyclonal goat anti-mouse-HRP (Agilent P0447 ...
• FMR1 loss results in early changes to intrinsic membrane excitability in human cellular models

  Sara G. Susco, et al., bioRxiv - Neuroscience 2020

  Quote: ... and anti-TRA-1-60 (Santa Cruz Biotechnology sc-21705). Antibodies used to assess tri-lineage potential were anti-AFP (Sigma A8452) ...
• Loss of function of the mitochondrial peptidase PITRM1 induces proteotoxic stress and Alzheimer’s disease-like pathology in human cerebral organoids

  Dina Ivanyuk, et al., bioRxiv - Neuroscience 2020

  Quote: ... mouse anti-VDAC1 (1:1000, Santa Cruz Biotechnologies #sc-390996).
• Loss of function of the mitochondrial peptidase PITRM1 induces proteotoxic stress and Alzheimer’s disease-like pathology in human cerebral organoids

  Dina Ivanyuk, et al., bioRxiv - Neuroscience 2020

  Quote: ... mouse anti-HSP60 (1:3000, Santa Cruz Biotechnologies #sc-271215); rabbit anti-LONP1 (1:3000 ...
• Loss of function of the mitochondrial peptidase PITRM1 induces proteotoxic stress and Alzheimer’s disease-like pathology in human cerebral organoids

  Dina Ivanyuk, et al., bioRxiv - Neuroscience 2020

  Quote: ... mouse anti-HSPA9 (1:3000, Santa Cruz Biotechnologies #sc-133137); mouse anti-HSP60 (1:3000 ...
• Long-term synaptic depression triggers local biogenesis of autophagic vesicles in dendrites and requires autophagic degradation

  Emmanouela Kallergi, et al., bioRxiv - Neuroscience 2020

  Quote: ... β III tubulin (Tuj1) (1:5000, Santa Cruz Biotechnology, sc-80005), actin (2Q1055 ...
• Human DICER helicase domain recruits PKR and modulates its antiviral activity

  Thomas C. Montavon, et al., bioRxiv - Microbiology 2021

  Quote: ... anti-TRBP (1:500, D-5 Santa Cruz sc-514124), anti-PKR (1:2500 ...
• Developmental Reactive Oxygen Species Target Histone Methylation to Individualize Stress resistance and Lifespan

  Daphne Bazopoulou, et al., bioRxiv - Molecular Biology 2019

  Quote: ... or anti-β-tubulin (Santa Cruz, sc-5274; 1:2,500) primary antibodies overnight at 4°C ...
• Loss of adipocyte identity through synergistic repression of PPARγ by TGF-β and mechanical stress

  Ewa Bielczyk-Maczyńska, et al., bioRxiv - Cell Biology 2019

  Quote: ... rabbit anti-CEBPα (Santa Cruz Biotech, sc-61, 1:1,000), mouse anti-YAP (Santa Cruz Biotech ...
• Loss of adipocyte identity through synergistic repression of PPARγ by TGF-β and mechanical stress

  Ewa Bielczyk-Maczyńska, et al., bioRxiv - Cell Biology 2019

  Quote: ... mouse anti-YAP (Santa Cruz Biotech, sc-101199, 1:500), chicken anti-GFP (Fisher Scientific ...
• DRP1-mediated regulation of mitochondrial dynamics determines the apoptotic response upon embryonic differentiation

  Barbara Pernaute, et al., bioRxiv - Developmental Biology 2019

  Quote: Primary antibodies used for immunofluorescence: Tom20 (1/100, Santa Cruz), ATP-b (1:100 ...
• Ubiquitin Ligase MARCH5 Regulates Apoptosis through Mediation of Stress-Induced and NOXA-Dependent MCL1 Degradation

  Seiji Arai, Sen Chen, Lisha Xie, Steven P. Balk, bioRxiv - Cancer Biology 2020

  Quote: ... anti-BIM (mouse, 1:500) (#sc-374358, Santa Cruz Biotechnology), anti-cleaved caspase 3 (CC3 ...
• Single-cell analysis of Foxp1-driven mechanisms essential for striatal development

  Ashley G. Anderson, et al., bioRxiv - Neuroscience 2019

  Quote: ... goat anti-FOXP2 (N-terminal) (1:500, Santa Cruz 21069), rabbit polyclonal anti-β-Tubulin (IB ...
• A RAD9-dependent cell cycle arrest in response to unresolved recombination intermediates in Saccharomyces cerevisiae

  Hardeep Kaur, GN Krishnaprasad, Michael Lichten, bioRxiv - Genetics 2019

  Quote: ... and rabbit anti-MYC (Santa Cruz, sc-789 1:250)] ...
• The nucleoporin ELYS regulates nuclear size by controlling NPC number and nuclear import capacity

  Predrag Jevtic, et al., bioRxiv - Cell Biology 2019

  Quote: ... and lamin B1 (Santa Cruz, sc-6217, goat, 1:500) in PBST with 1% BSA for 4 hours at room temperature or overnight at 4°C ...
• Ubiquitin Ligase MARCH5 Regulates Apoptosis through Mediation of Stress-Induced and NOXA-Dependent MCL1 Degradation

  Seiji Arai, Sen Chen, Lisha Xie, Steven P. Balk, bioRxiv - Cancer Biology 2020

  Quote: ... anti-MCL1 (mouse, 1:1000) (#sc-12756, Santa Cruz Biotechnology), anti-Mfn1 (mouse ...
• Ubiquitin Ligase MARCH5 Regulates Apoptosis through Mediation of Stress-Induced and NOXA-Dependent MCL1 Degradation

  Seiji Arai, Sen Chen, Lisha Xie, Steven P. Balk, bioRxiv - Cancer Biology 2020

  Quote: ... anti-Mfn1 (mouse, 1:1000) (#sc-166644, Santa Cruz Biotechnology), anti-MiD49 (SMCR7 ...
• Ubiquitin Ligase MARCH5 Regulates Apoptosis through Mediation of Stress-Induced and NOXA-Dependent MCL1 Degradation

  Seiji Arai, Sen Chen, Lisha Xie, Steven P. Balk, bioRxiv - Cancer Biology 2020

  Quote: ... anti-p53 (mouse, 1:1000) (#sc-126, Santa Cruz Biotechnology), anti-p62 (rabbit ...
• Regulation of eIF6 through multisite and sequential phosphorylation by GSK3β

  Courtney F. Jungers, et al., bioRxiv - Molecular Biology 2019

  Quote: ... or anti-eIF6 monoclonal antibody (1:350) (Santa Cruz Biotechnology) and incubated in a humidified chamber at room temperature (RT ...
• Rho-kinase mediates the anorexigenic action of melanocortin by suppressing AMPK

  Sang Soo Kim, et al., bioRxiv - Neuroscience 2019

  Quote: ... anti-mouse Gα12 (sc-515445, 1:100, Santa Cruz Biotechnology), or anti-mouse Gαs (sc-135914 ...
• Dock5 is a new regulator of microtubule dynamic instability through GSK3β inhibition in osteoclasts

  Sarah Guimbal, et al., bioRxiv - Cell Biology 2019

  Quote: ... rat anti-alpha tubulin (1/200, Santa Cruz, #sc-53030) or rabbit anti-Dock5 (1/100 ...
• p57Kip2 regulates embryonic haematopoietic stem cell numbers by controlling the size of the sympathoadrenal progenitor pool

  Chrysa Kapeni, et al., bioRxiv - Developmental Biology 2021

  Quote: ... and Sox10 (goat N-20, 1:250, Santa Cruz Biotechnology). The next day ...
• A single-cell transcriptomic and anatomic atlas of mouse dorsal raphe Pet1 neurons

  Benjamin W. Okaty, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-Pax5 (1:1000, goat polyclonal, Santa Cruz, sc-1974), anti-SATB2 (1:1000 ...
• A single-cell transcriptomic and anatomic atlas of mouse dorsal raphe Pet1 neurons

  Benjamin W. Okaty, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-Doublecortin (1:1000, goat polyclonal, Santa Cruz, SC-8066), and anti-Ki-67(1:1000 ...
• Neurodegeneration induces a developmental RNA processing program by calpain-mediated MBNL2 degradation

  Lee-Hsin Wang, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-Histone H3 (sc-8654, 1:5000, Santa Cruz Biotechnology).
• Simultaneous expression of UV and violet SWS1 opsins expands the visual palette in a group of freshwater snakes

  Einat Hauzman, et al., bioRxiv - Evolutionary Biology 2021

  Quote: ... goat anti-SWS1 (Santa Cruz Biotechnology; sc-14363; 1:200), rabbit anti-LWS (Chemicon International ...
• Tracheal motile cilia in mice require CAMSAP3 for formation of central microtubule pair and coordinated beating

  Hiroko Saito, et al., bioRxiv - Cell Biology 2021

  Quote: ... mouse monoclonal anti-Chibby (Santa Cruz sc-101551, 1:100). The following secondary antibodies were used ...
• Sex determination gene transformer regulates the male-female difference in Drosophila fat storage via the adipokinetic hormone pathway

  Lianna W. Wat, et al., bioRxiv - Physiology 2021

  Quote: ... and mouse anti-actin (1:100; Santa Cruz #sc-8432).