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4951 - 5000 of 8510 citations for 6 Chloro 2 3 diphenylimidazo 1 2 b pyridazine since 2019

• Annexin A1 tripeptide mimetic increases sirtuin-3 to augment mitochondrial function and limit ischemic kidney injury

  Hagir Suliman, et al., bioRxiv - Physiology 2020

  Quote: ... PARK2 (1:500; Cat. No. sc-32282; Santa Cruz Biotechnology); light chain 3B protein (LC3I/II ...
• Transcriptional repression of Myc underlies AGO1’s tumour suppressor function

  Olga Zaytseva, et al., bioRxiv - Developmental Biology 2020

  Quote: ... Myc N (Rabbit 1 in 500 Santa Cruz d46-507), Fibrillarin (Rabbit 1 in 500 Abcam ab5821) ...
• Soft limbal niche maintains stem cell compartmentalization and function through YAP

  Swarnabh Bhattacharya, et al., bioRxiv - Cell Biology 2021

  Quote: ... mouse anti-YAP (1:400, Santa cruz biotechnology, sc-101199) and rabbit anti-GAPDH (1:1000 ...
• Mosquito defensins enhance Japanese encephalitis virus infection by facilitating virus adsorption and entry within mosquito

  Ke Liu, et al., bioRxiv - Microbiology 2020

  Quote: ... goat anti-mouse IgG-HRP antibody (1:10000; Santa Cruz), Alexa Fluor 405-conjugated anti-mouse IgG antibody (1:500 ...
• Chemogenetic manipulation of microglia inhibits neuroinflammation and neuropathic pain in mice

  Min-Hee Yi, et al., bioRxiv - Neuroscience 2020

  Quote: ... and GAPDH (1:1000; sc-32233, RRID:AB_627679, Santa Cruz Biotechnology). Membranes were incubated with horseradish peroxidase-conjugated goat anti-mouse IgG (1:3,000 ...
• Reactive Astrocytes Prevent Maladaptive Plasticity after Ischemic Stroke

  Markus Aswendt, et al., bioRxiv - Neuroscience 2021

  Quote: ... goat anti-Sox2 (1:200, sc-7379, Santa Cruz Biotechnology), rabbit anti S100 (1:200 ...
• Insulin-like growth factor 2 (IGF2) protects against Huntington’s disease through the extracellular disposal of protein aggregates

  Paula García-Huerta, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-polyUbiquitin 1:5000 (Santa Cruz, Cat. n° SC-8017), anti-DARPP32 1:1000 (Millipore ...
• Insulin-like growth factor 2 (IGF2) protects against Huntington’s disease through the extracellular disposal of protein aggregates

  Paula García-Huerta, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-GAPDH 1:2000 (Santa Cruz, Cat. n° SC-365062), anti-HA 1:500 (Santa Cruz ...
• The dynamic equilibrium of nascent and parental MCMs safeguards replicating genomes

  Hana Sedlackova, et al., bioRxiv - Cell Biology 2019

  Quote: ... PCNA (mouse, Santa Cruz, sc-56, 1:1000 for WB), RPA32-phospho-S33 (rabbit ...
• Mitotic checkpoint protein Mad1 is required for early Nup153 recruitment to chromatin and nuclear envelope integrity

  Ikram Mossaid, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-Mad1 (Santa Cruz, sc-67338; IF 1:100), rabbit anti-Mad2 (Covance ...
• Abnormal Cannabidiol protects pancreatic beta cells in mouse models of experimental Type 1 diabetes

  Isabel Gonzalez-Mariscal, et al., bioRxiv - Pharmacology and Toxicology 2020

  Quote: ... rabbit anti-insulin (1:100; sc-9168) from Santa Cruz Biotechnology ...
• Selective localization of Mfn2 near PINK1 enable its preferential ubiquitination by Parkin on mitochondria

  Marta Vranas, et al., bioRxiv - Biochemistry 2021

  Quote: ... rabbit anti-Mfn1 and anti-Mfn2 (1:2000, Santa Cruz), and mouse anti-VDAC1 (1:10000 ...
• Fibroblast growth factor-9 expression in airway epithelial cells amplifies the type I interferon response and alters influenza A virus pathogenesis

  Bradley E. Hiller, et al., bioRxiv - Immunology 2021

  Quote: ... anti-SCGB1A1 goat polyclonal antibody Sc9772 (1:200) (Santa Cruz). Embedding and sectioning were performed by the Musculoskeletal Histology and Morphometry Core at Washington University School of Medicine ...
• Unraveling the roles of Mast4 in amelogenesis via regulating DLX3 and stem cell maintenance of mouse incisors

  Dong-Joon Lee, et al., bioRxiv - Developmental Biology 2021

  Quote: ... anti-HA (sc-7392, Santa cruz Biotechnology, USA; 1:1000), anti-Lamin B (SC-374015 ...
• A drug-screening platform based on organotypic cultures identifies vulnerabilities to prevent local relapse and treat established brain metastasis

  Lucía Zhu, et al., bioRxiv - Cancer Biology 2020

  Quote: ... HSP70/ HSC70 W27 (1:500; sc-24; Santa Cruz Biotechnology), AHR (1:300 ...
• DNA damage response at telomeres boosts the transcription of SARS-CoV-2 receptor ACE2 during aging

  Sara Sepe, et al., bioRxiv - Cell Biology 2021

  Quote: ... rabbit polyclonal anti-53BP1 (1:1000, sc-22760, Santa Cruz), mouse monoclonal anti-phospho-Histone H2A.X (1:500 ...
• Cofilin pathology is a new player on α-synuclein-induced spine impairment in models of hippocampal synucleinopathy

  MI Oliveira da Silva, et al., bioRxiv - Neuroscience 2021

  Quote: ... and mouse anti-GAPDH 1:1000 (Santa Cruz, sc-166574) diluted in 5%milk/TBS-T or 5%BSA ...
• Previous estradiol treatment during midlife maintains transcriptional regulation of memory-related proteins by ERα in the hippocampus in a rat model of menopause

  Nina E. Baumgartner, et al., bioRxiv - Neuroscience 2021

  Quote: ... and loading control protein β-actin (Santa Cruz, 1:5000). Secondary antibodies conjugated to HRP were used ...
• Insulin-dependent maturation of newly generated olfactory sensory neurons after injury

  Akihito Kuboki, et al., bioRxiv - Neuroscience 2021

  Quote: ... and anti-c-Fos (rabbit IgG, 1:1,000; Santa Cruz Biotechnology Inc. ...
• The E3 ubiquitin ligase HECTD1 contributes to cell cycle progression through an effect on mitosis

  Natalie Vaughan, et al., bioRxiv - Cell Biology 2021

  Quote: ... Anti-Cyclin B1 (Santa Cruz Biotechnology, sc-245, 1/1,000), anti-phospho-Histone H3 (Ser28 ...
• Caveolae mediated endocytosis of VLDL particles in macrophages requires NPC1 and STARD3 for further lysosomal processing

  Lei Deng, et al., bioRxiv - Cell Biology 2021

  Quote: Human LPL F:1 (Santa Cruz Biotechnology, Inc., California, USA) and 5D2 antibodies were added to cell culture medium 2 hours prior to emulsion loading at the concentration of 2 μg/ml (1:100 dilution).
• Alleviation of neuropathic pain by over-expressing a soluble colony-stimulating factor 1 receptor

  Svetlana Gushchina, et al., bioRxiv - Neuroscience 2020

  Quote: ... Donkey anti-goat IgG-HRP (1:10,000, Santa Cruz Biotechnology) was applied to the membrane for 2 h at room temperature.
• Coupling adipose tissue architecture and metabolism via cytoophidia

  Jingnan Liu, et al., bioRxiv - Developmental Biology 2021

  Quote: ... goat anti CTPS (1:400, Santa Cruz Catalogue no.33304) was used as the primary antibody ...
• ACTIN Anchors the Highly Oligomeric DRP1 at Mitochondria-Sarcoplasmic Reticulum Contact Sites in Adult Murine Heart: Its Functional Implication

  Celia Fernandez-Sanz, et al., bioRxiv - Physiology 2021

  Quote: ... and/or rabbit polyclonal TOM20 antibody (Santa Cruz, 1:50). Alexa Fluor®488 or 647 were used as secondary antibodies ...
• Mast cell-specific receptor/corticotropin-releasing factor axis regulates alcohol withdrawal-associated headache

  Hyeonwi Son, et al., bioRxiv - Neuroscience 2021

  Quote: ... which was immunoblotted with anti-CRF (Santa Cruz, 1:500) and anti-β-actin (Cell Signaling ...
• Aberrant claudin-6–adhesion signal promotes endometrial cancer progression via estrogen receptor α

  Manabu Kojima, et al., bioRxiv - Cancer Biology 2020

  Quote: ... or 0.1 nM of SGK-1 inhibitor (Santa Cruz Technology) one or two days after plating ...
• Syd/JIP3 Controls Tissue Size by Regulating Diap1 Protein Turnover Downstream of Yorkie/YAP

  Vakil Ahmad, et al., bioRxiv - Developmental Biology 2020

  Quote: ... mouse anti-c-IAP(1:1000, Cat #271419, Santa Cruz), rabbit anti-β-Actin (1:1000 ...
• UDP-glucose pyrophosphorylase 2, a regulator of glycosylation and glycogen, is essential for pancreatic cancer growth

  Andrew L. Wolfe, et al., bioRxiv - Cancer Biology 2020

  Quote: ... and UGP2 (Santa Cruz Biotechnology sc-377089 at 1:200). Immunohistochemistry of historic deidentified PDAC samples used antibodies against YAP1 (Cell Signaling 14074 ...
• Molecular basis of functional compatibility between ezrin and other actin-membrane associated proteins during cytokinesis

  Guang Yang, et al., bioRxiv - Cell Biology 2020

  Quote: ... mouse anti-ezrin (sc-58758, Santa Cruz Biotechnology; 1:100), rabbit anti-radixin (EP1862Y ...
• BNIP3 phosphorylation by JNK1/2 promotes mitophagy via enhancing its stability under hypoxia

  Yun-Ling He, et al., bioRxiv - Cell Biology 2020

  Quote: ... anti-TOMM20 (1:5,000, rabbit pAb, Santa Cruz, sc-11415), anti-LC3B (1:4,000 ...
• SETDB1 regulates microtubule dynamics

  Rosari Hernandez-Vicens, et al., bioRxiv - Cell Biology 2021

  Quote: ... mouse anti-GFP (1:500, Santa Cruz Biotechnology sc-9996) and rabbit anti-FLAG (1:1,000 ...
• Global and context-specific transcriptional consequences of oncogenic Fbw7 mutations

  H. Nayanga Thirimanne, et al., bioRxiv - Cancer Biology 2021

  Quote: ... and (Rabbit normal IgG (1:50, Santa Cruz sc-2027). For western blots and immunoprecipitation we used anti-Fbw7 Bethyl A301-720A.
• Proton export drives the Warburg Effect

  Shonagh Russell, et al., bioRxiv - Cancer Biology 2021

  Quote: ... and GAPDH (1:1000, Santa Cruz Biotechnology, TX, se-25778). For visualization ...
• Oncogenic c-Myc induces replication stress by increasing cohesins chromatin occupancy

  Silvia Peripolli, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-CyclinE (Santa Cruz Biotechnology HE12 sc-247 1:1000), anti-CTCF (Chip-grade AB70303 Abcam 1:5000) ...
• Immunosuppressive role of PGE2 during human tuberculosis

  Joaquín Miguel Pellegrini, et al., bioRxiv - Immunology 2020

  Quote: ... and 1% bovine serum albumin (Santa Cruz Biotechnology, sc-2323A) for 15 min ...
• Developmental pathways regulate cytokine-driven effector and feedback responses in the intestinal epithelium

  Håvard T. Lindholm, et al., bioRxiv - Immunology 2020

  Quote: ... MUC2 (1:200, rabbit pAb, Santa Cruz Biotechnology, sc-7963) and RELM-beta (1:200 ...
• Her9/Hes4 is required for retinal photoreceptor development, maintenance, and survival

  Cagney E. Coomer, et al., bioRxiv - Developmental Biology 2020

  Quote: ... or anti-β actin (mouse monoclonal, 1:1000, Santa Cruz)/PBST solution overnight at 4°C ...
• Differential expression levels of Sox9 in early neocortical radial glial cells regulate the decision between stem cell maintenance and differentiation

  Jaime Fabra-Beser, et al., bioRxiv - Neuroscience 2020

  Quote: ... rabbit anti-Cux1 (1:300, Santa Cruz Biotechnology, sc-13024); rabbit anti-Cux1 (1:1000 ...
• Meiosis-Specific Cohesin Complexes Display Distinct and Essential Roles in Mitotic ESC Chromosomes

  Eui-Hwan Choi, et al., bioRxiv - Molecular Biology 2021

  Quote: ... anti-mouse OCT3/4 (Santa Cruz; sc-5297; 1:3,000), anti-rat RPA (Cell signaling ...
• Phosphorylation of PNKP mediated by CDKs promotes end-processing of Okazaki fragments during DNA replication

  Kaima Tsukada, et al., bioRxiv - Molecular Biology 2021

  Quote: ... PCNA (rabbit, 1:500, Santa Cruz Biotechnology, cat# sc-7907), KAP1 (rabbit ...
• A split GFP system to enhance spatial and temporal sensitivity of translating ribosome affinity purification (TRAP)

  Kasia Dinkeloo, et al., bioRxiv - Molecular Biology 2021

  Quote: ... or α-Myc (Clone A-14, Santa Cruz; 1:1000) and secondary antibody Horse Radish Peroxidase (HRP)-α-mouse (ThermoFisher Scientific ...
• GENERATION AND CHARACTERIZATION OF IMMORTALIZED MOUSE CORTICAL ASTROCYTES FROM WILDTYPE AND CONNEXIN43 KNOCKOUT MICE

  Antonio Cibelli, et al., bioRxiv - Neuroscience 2020

  Quote: ... goat anti-GS 1:500 (Santa Cruz, cat# SC-6640), and goat anti-AQP4 1:500 (Santa Cruz ...
• The intraflagellar transport protein IFT20 recruits ATG16L1 to early endosomes to promote autophagosome formation in T cells

  Francesca Finetti, et al., bioRxiv - Immunology 2020

  Quote: ... or mouse anti-BECLIN 1 mAb (sc-48341, Santa Cruz), and protein A-Sepharose (PAS ...
• NAMPT-derived NAD⁺ fuels PARP1 to promote skin inflammation through parthanatos

  Francisco J. Martínez-Morcillo, et al., bioRxiv - Immunology 2021

  Quote: ... mouse anti-p63 (Santa Cruz Biotechnology, sc-7255, 1:200), rabbit Anti-Active Caspase-3 (Bd Bioscience ...
• Immunoresolvents Support Skeletal Myofiber Regeneration via Actions on Myeloid and Muscle Stem Cells

  James F. Markworth, et al., bioRxiv - Immunology 2020

  Quote: ... and rabbit polyclonal CD163 (Santa Cruz, sc-33560, 1:50). Primary antibodies used on rat muscle included myosin heavy chain type I (DSHB ...
• Immunoresolvents Support Skeletal Myofiber Regeneration via Actions on Myeloid and Muscle Stem Cells

  James F. Markworth, et al., bioRxiv - Immunology 2020

  Quote: ... and rabbit polyclonal CD163 (Santa Cruz, sc-33560, 1:50). Antibody binding was visualized with standard Alexa Fluor secondary antibodies (Invitrogen ...
• Eomesodermin is functionally conserved between zebrafish and mouse in spite of different mutant phenotypic severities, and controls left/right organiser formation via interlocking feedforward loops

  Conor D. Talbot, et al., bioRxiv - Developmental Biology 2020

  Quote: ... rabbit anti-Eomes NTD (Santa Cruz, sc-98555, 1:1000) and rat anti-Eomes (eBioscience ...
• KIF18B is a cell-type specific regulator of spindle orientation in the epidermis

  Rebecca S. Moreci, Terry Lechler, bioRxiv - Cell Biology 2021

  Quote: ... Rat anti-α Tubulin (1:2000, Santa Cruz, sc-53029), Rabbit anti-KIF18B (1:500 ...
• A RIPOR2 in-frame deletion is a frequent and highly penetrant cause of adult-onset hearing loss

  Suzanne E. de Bruijn, et al., bioRxiv - Genetics 2019

  Quote: ... anti-GFP (mouse; 1:1000; cat.#SC-9996; Santa Cruz).
• ARMC9 and TOGARAM1 define a Joubert syndrome-associated protein module that regulates axonemal post-translational modifications and cilium stability

  Brooke L. Latour, et al., bioRxiv - Genetics 2019

  Quote: ... goat anti-γ- tubulin (Santa Cruz, SC-7396 1:200), rabbit anti-ARL13B (Proteintech ...