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5151 - 5200 of 8510 citations for 6 Chloro 2 3 diphenylimidazo 1 2 b pyridazine since 2019

• Endocytosis Inhibitors Block SARS-CoV-2 Pseudoparticle Infection of Mink Lung Epithelium

  Ann Song, Rattapol Phandthong, Prue Talbot, bioRxiv - Cell Biology 2023

  Quote: ... mouse anti-TMPRSS2 (1:200; Santa Cruz Biotechnology, Dallas, TX), and mouse-EEA1 (1:200 ...
• The oncogene cyclin D1 promotes bipolar spindle integrity under compressive force

  Renaldo Sutanto, et al., bioRxiv - Cell Biology 2023

  Quote: ... Normal mouse IgG (1:100, Santa Cruz Biotechnology sc-2025) was used as a block before incubating in pre-conjugated mouse anti-α-tubulin DM1α Alexa Fluor 488 ...
• Histone lactylation antagonizes senescence and skeletal muscle aging via facilitating gene expression reprogramming

  Xuebin Zhang, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-β-ACTIN (Santa Cruz Biotechnology, sc-47778, 1:1000), anti-α-TUBULIN (Sigma ...
• Nuclear MTHFD2 secures mitosis progression by preserving centromere integrity

  Natalia Pardo-Lorente, et al., bioRxiv - Cell Biology 2023

  Quote: ... and VDAC1/Porin (Santa Cruz Biotechnology; #sc-390996; 1:200). The following secondary antibodies were used ...
• Drug-induced change in transmitter identity is a shared mechanism generating cognitive deficits

  Pratelli Marta, et al., bioRxiv - Neuroscience 2023

  Quote: ... goat-anti-doublecortin (Santa Cruz, sc-8066, RRID:AB_2088494, 1:300) and rabbit-anti-Ki67 (Cell Signaling ...
• Preserved striatal innervation and motor function despite severe loss of nigral dopamine neurons following mitochondrial dysfunction induced by mtDNA mutations

  Thomas Paß, et al., bioRxiv - Neuroscience 2023

  Quote: ... and monoclonal α-TH (1:500; Santa Cruz, sc-25269). Sections were washed (0.2% Triton X-100 in PBS ...
• Neurotrophin-3 from the dentate gyrus supports postsynaptic sites of mossy fiber-CA3 synapses and contextual memory

  Ji-Wei Tan, et al., bioRxiv - Neuroscience 2023

  Quote: ... goat anti-doublecortin (1:200; Santa Cruz Biotechnology #SC-8066), rabbit anti-GluR1 (1:250 ...
• 3D human retinal organoid model for the study of early diabetic retinopathy

  Luisa de Lemos, et al., bioRxiv - Neuroscience 2023

  Quote: ... mouse anti-SOD1 (1:1000, sc-31989, Santa Cruz Biotechnology), rabbit anti-SOD2 (1:1000 ...
• 3D human retinal organoid model for the study of early diabetic retinopathy

  Luisa de Lemos, et al., bioRxiv - Neuroscience 2023

  Quote: ... mouse anti-Catalase (1:500, sc-271803, Santa Cruz Biotechnology), mouse anti-SOD1 (1:1000 ...
• Primordial germ cell DNA demethylation and development require DNA translesion synthesis

  Pranay Shah, et al., bioRxiv - Developmental Biology 2023

  Quote: ... anti-TFAP2C (1:100, catalog no. sc-12762; Santa Cruz); anti-SOX17 (1:200 ...
• The differentiation and integration of the hippocampal dorsoventral axis are controlled by two nuclear receptor genes

  Xiong Yang, et al., bioRxiv - Developmental Biology 2023

  Quote: ... mouse anti-GAPDH (1:1000, Santa Cruz, Cat # sc-32233). The following secondary antibodies were applied in the study ...
• The differentiation and integration of the hippocampal dorsoventral axis are controlled by two nuclear receptor genes

  Xiong Yang, et al., bioRxiv - Developmental Biology 2023

  Quote: ... goat anti-Dcx (1:500, Santa Cruz, Cat # sc-8066). The following secondary antibodies were used in the study ...
• The differentiation and integration of the hippocampal dorsoventral axis are controlled by two nuclear receptor genes

  Xiong Yang, et al., bioRxiv - Developmental Biology 2023

  Quote: ... rabbit anti-Nestin (1:200, Santa Cruz, Cat # sc-20978), goat anti-Dcx (1:500 ...
• The differentiation and integration of the hippocampal dorsoventral axis are controlled by two nuclear receptor genes

  Xiong Yang, et al., bioRxiv - Developmental Biology 2023

  Quote: ... goat anti-Lhx2 (1:200, Santa Cruz, Cat # sc-19344), goat anti-Lhx5 (1:200 ...
• Ser149 is another potential 14-3-3 ε binding site of Cdc25B in the G2/M transition of mouse fertilized eggs

  Wen-Ning He, et al., bioRxiv - Cell Biology 2023

  Quote: ... and rabbit anti-β-actin (1:400) (Santa Cruz Biotechnology). For detection ...
• CD20 is a mammalian odorant receptor expressed in a subset of olfactory sensory neurons that mediates innate avoidance of predators

  Hao-Ching Jiang, et al., bioRxiv - Animal Behavior and Cognition 2023

  Quote: ... goat anti-MS4A1 (1:50, Santa Cruz Biotechnology, #sc-7735), rat anti-MS4A1 (1:100 ...
• RNF43 mutations facilitate colorectal cancer metastasis via formation of a tumour-intrinsic niche

  Jeroen M. Bugter, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and stained against APC (sc-7930, Santa Cruz, 1:1.000) and Actin (691001 ...
• A self-renewing biomimetic skeletal muscle construct engineered using induced myogenic progenitor cells

  Inseon Kim, et al., bioRxiv - Bioengineering 2023

  Quote: ... and anti-myogenin (F5D) (1:250, Santa Cruz, sc-12732). The secondary antibodies used in this study were Goat Anti-Mouse IgG2b (Alexa Fluor 546 ...
• Virally induced lipid droplets are a platform for innate immune signalling complexes

  EA Monson, et al., bioRxiv - Immunology 2023

  Quote: ... mouse monoclonal αACOX1 (1:1000; sc-517306, Santa Cruz Biotechnology), rabbit monoclonal αPerilipin-2 (1:2000 ...
• Virally induced lipid droplets are a platform for innate immune signalling complexes

  EA Monson, et al., bioRxiv - Immunology 2023

  Quote: ... mouse monoclonal αmfn1 (1:1000; sc-166644, Santa Cruz Biotechnology), mouse monoclonal αACOX1 (1:1000 ...
• Regulation of oncogene-induced senescence by the MRE11 and TREX1 nucleases

  Hervé Técher, et al., bioRxiv - Molecular Biology 2023

  Quote: ... anti-p53 (1/500, Santa Cruz, clone DO7 sc-47698). Following antibodies were purchased from Abcam ...
• MCT4 and CD147 co-localize with MMP14 in invadopodia and autolysosomes and collectively stimulate breast cancer cell invasion by increasing extracellular matrix degradation

  Signe Meng, et al., bioRxiv - Cancer Biology 2023

  Quote: ... against MCT4 (#376140) and LAMP-1 (#20011) from Santa Cruz; against MMP14 (#271840 and #192782) ...
• Nuclear damage in LMNA mutant iPSC-derived cardiomyocytes is associated with impaired lamin localization to the nuclear envelope

  Melanie Wallace, et al., bioRxiv - Cell Biology 2023

  Quote: ... The Lamin A/C antibody used (Santa Cruz; E-1) targeted the N-terminus (AA 2-29 ...
• Evidence of target-mediated miRNA degradation in Drosophila ovarian cell culture

  Natalia Akulenko, et al., bioRxiv - Molecular Biology 2023

  Quote: ... or goat anti-CyclinA (1:100, Santa Cruz, N-15). Then ...
• 3D human retinal organoid model for the study of early diabetic retinopathy

  Luisa de Lemos, et al., bioRxiv - Neuroscience 2023

  Quote: ... goat anti-BRN3a (1:100, sc-31989, Santa Cruz Biotechnology), goat anti-OTX2 (1:100 ...
• A CRISPR screen of HIV dependency factors reveals CCNT1 is non-essential in T cells but required for HIV-1 reactivation from latency

  Terry L Hafer, et al., bioRxiv - Microbiology 2023

  Quote: ... mouse α-CCNT2 (Santa Cruz Biotechnology, sc-81243, 1:500), and rabbit α-actin (Sigma-Aldrich ...
• Development of Gemcitabine-Modified miRNA Mimics as Cancer Therapeutics for Pancreatic Ductal Adenocarcinoma

  John G. Yuen, et al., bioRxiv - Cancer Biology 2023

  Quote: ... or mouse anti-GAPDH antibody (Santa Cruz, sc47724, 1:100,000). Primary antibodies were diluted in 5% milk (Bio-Rad ...
• The differentiation and integration of the hippocampal dorsoventral axis are controlled by two nuclear receptor genes

  Xiong Yang, et al., bioRxiv - Developmental Biology 2023

  Quote: ... goat anti-NeuroD1 (1:200, Santa Cruz, Cat # sc-1084), goat anti-Lhx2 (1:200 ...
• C4 induces pathological synaptic loss by impairing AMPAR trafficking

  Rhushikesh A. Phadke, et al., bioRxiv - Neuroscience 2023

  Quote: ... Mouse anti-GAPDH (1:1000, Santa Cruz Biotechnology, sc-47724), Mouse anti-FLAG (1:1000 ...
• Capsicum chinense Jacq. derived glutaredoxin (CcGRXS12) alters phytohormonal pathways and redox status of the cells to confer resistance against pepper mild mottle virus (PMMoV-I)

  R. M. Saravana Kumar, et al., bioRxiv - Biochemistry 2023

  Quote: ... GFP specific polyclonal antibody (1/250; Santa Cruz Biotechnology, INC.) and PMMoV-I CP (1/1000 ...
• Cystin is required for maintaining fibrocystin (FPC) levels and safeguarding proteome integrity in mouse renal epithelial cells A mechanistic connection between the kidney defects in cpk mice and human ARPKD

  Yiming Zhang, et al., bioRxiv - Cell Biology 2023

  Quote: ... β-actin (mouse, mAb, Santa Cruz; sc-47778; 1:3000), Ift88 (rabbit pAb ...
• Panton-Valentine leukocidin-induced neutrophil extracellular traps lack antimicrobial activity and are readily induced in patients with recurrent PVL⁺-Staphylococcus aureus infections

  Hina Jhelum, et al., bioRxiv - Immunology 2022

  Quote: ... 10 µg/ml CD88 (S5/1)-FITC (Santa Cruz Biotechnology) and 10 µg/ml anti-human C5L2-APC (BioLegend ...
• Autophagy mediates cancer cell resistance to doxorubicin induced by the Programmed Death 1/Programmed Death Ligand 1 immune checkpoint axis

  Lori Minassian, et al., bioRxiv - Cancer Biology 2023

  Quote: ... rabbit anti-α-actinin (Santa Cruz sc-15335, 1:1000), or mouse anti-β-actin (Sigma Aldrich A5441 ...
• Human papillomavirus 16 E2 interaction with TopBP1 is required for E2 and viral genome stability during the viral life cycle

  Apurva T. Prabhakar, et al., bioRxiv - Cancer Biology 2023

  Quote: ... HPV16 E7 1:200 (Santa Cruz, catalog no. sc-6981), E2 tag [5E11] 1:1000 (Abcam ...
• Modelling drug responses and evolutionary dynamics using triple negative breast cancer patient-derived xenografts

  Abigail Shea, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and probed using BRCA1 (Santa Cruz, sc-6954, 1:200) and β-tubulin (Cell Signaling Technology ...
• CRISPR/Cas9-mediated knockout of the ubiquitin variant Ub^KEKS reveals a role in regulating nucleolar structures and composition

  Julie Frion, et al., bioRxiv - Cell Biology 2023

  Quote: ... UBF (F-9, sc-13125, Santa Cruz Biotechnology , 1:300) or fibrillarin (38F3 ...
• Intermediate filament dysregulation and astrocytopathy in the human disease model of KLHL16 mutation in giant axonal neuropathy (GAN)

  Rachel Battaglia, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse anti-Gigaxonin (Santa Cruz Biotechnology, F3, WB 1:200), rabbit anti-Vimentin (Cell Signaling Technology ...
• Cell division tracing combined with single-cell transcriptomics reveals new cell types and differentiation paths in the regenerating mouse lung

  Leila R. Martins, et al., bioRxiv - Cell Biology 2023

  Quote: ... Cyp2f2-Alexa Fluor 647 (1:1000, #sc-374540, Santa Cruz), GFP-FITC (1:500 ...
• A hierarchical pathway for assembly of the distal appendages that organize primary cilia

  Tomoharu Kanie, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse IgG2a anti-RAB34 (sc-365986, Santa Cruz, 1:250), and mouse IgG2b anti-FOP (H00011116-M01 ...
• A hierarchical pathway for assembly of the distal appendages that organize primary cilia

  Tomoharu Kanie, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse IgG2a anti-MYO5A (sc-365986, Santa Cruz, 1:1000), and mouse IgG2b anti-FOP (H00011116-M01 ...
• EHD1-dependent traffic of IGF-1 receptor to the cell surface is essential for Ewing sarcoma tumorigenesis and metastasis

  Sukanya Chakraborty, et al., bioRxiv - Cancer Biology 2023

  Quote: ... IGF-1 Receptor α mAb(1H7) (Santa Cruz; #sc-461); doxycycline (Sigma Aldrich ...
• Arginine shortage induces replication stress and confers genotoxic resistance by inhibiting histone H4 translation and promoting PCNA polyubiquitination

  Yi-Chang Wang, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-cyclin A (1:1000; Cat# sc-751, Santa Cruz), anti-cyclin B1 (1:1000 ...
• MARCH5-dependent NLRP3 ubiquitination is an essential step for NEK7 docking on the mitochondria

  Yeon-Ji Park, et al., bioRxiv - Immunology 2023

  Quote: ... anti-IL-1β (1:1,000, sc-12742, Santa Cruz biotechnology), anti-mouse caspase-1 (1:1,000 ...
• A Cas9-fusion proximity-based approach generates an Irak1-Mecp2 tandem duplication mouse model for the study of MeCP2 duplication syndrome

  Eleonora Maino, et al., bioRxiv - Genetics 2023

  Quote: ... rabbit monoclonal anti-GAPDH (sc-47724, Santa Cruz, 1:10000) overnight at 4C ...
• Matrix Gla Protein acts as a driver of stemness and tumor initiation in ovarian cancer

  V. Nieddu, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Lamin A/C (Santa Cruz, cat# sc-7292, 1:500), α-tubulin (Santa Cruz ...
• In vivo functional genomics identifies essentiality of potassium homeostasis in medulloblastoma

  Jerry J. Fan, et al., bioRxiv - Cancer Biology 2023

  Quote: ... mouse anti-PCNA (Santa Cruz Biotechnology #sc-56, 1:200), mouse anti-SOX2 (abcam #ab79351 ...
• Loss of EED in the oocyte causes initial fetal growth restriction followed by placental hyperplasia and offspring overgrowth

  Ruby Oberin, et al., bioRxiv - Developmental Biology 2023

  Quote: ... Mouse anti-PLAC1 (G-1) (Santa Cruz, Cat# sc-365919) primary antibody was applied at an appropriate concentration for 1 hour ...
• Tetherin antagonism by SARS-CoV-2 enhances virus release: multiple mechanisms including ORF3a-mediated defective retrograde traffic

  Hazel Stewart, et al., bioRxiv - Cell Biology 2022

  Quote: ... goat anti-EF2 (Santa Cruz, C-14, WB 1:10,000), mouse anti- tubulin (Proteintech ...
• SLC15A4 controls endolysosomal TLR7-9 responses by recruiting the innate immune adaptor TASL

  Haobo Zhang, et al., bioRxiv - Immunology 2023

  Quote: ... and mouse anti-LAMP2 (sc-18822, Santa Cruz, 1:1,000) in blocking solution ...
• A dual, catalytic role for the fission yeast Ccr4-Not complex in gene silencing and heterochromatin spreading

  Drice Challal, et al., bioRxiv - Genetics 2023

  Quote: ... and 1:5000 goat anti-mouse IgG-HRP (Santa Cruz Biotechnology ...