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5051 - 5100 of 8510 citations for 6 Chloro 2 3 diphenylimidazo 1 2 b pyridazine since 2019

• High-order thalamic and motor cortex inputs integrate sublinearly into tuft dendrites of pyramidal neurons in mouse somatosensory cortex

  Young-Eun Han, et al., bioRxiv - Neuroscience 2022

  Quote: ... somatostatin (1:50, Santa Cruz Biotechnology, Dallas, TX, sc-47706), vasoactive intestinal peptide (VIP ...
• Low-efficiency conversion of proliferative glia into induced neurons by Ascl1 in the postnatal mouse cerebral cortex in vivo

  Chiara Galante, et al., bioRxiv - Neuroscience 2022

  Quote: ... Doublecortin (DCX, goat, 1:250, Santa Cruz Biotechnology, sc-8066); Green Fluorescent Protein (GFP ...
• Nuclear inhibitor of protein phosphatase 1 (NIPP1) regulates CNS tau phosphorylation and myelination during development

  Cody McKee, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-PP1 (1:1,000; E-9, Santa Cruz Biotechnology, Inc.), anti-pAKT (Ser473 ...
• CCDC66 regulates primary cilium length and signaling competence via multi-site interactions with transition zone and axonemal proteins

  Deniz Conkar, et al., bioRxiv - Cell Biology 2022

  Quote: ... mouse anti-PCM1 1:1000 (sc-398365, Santa Cruz Biotechnology), rabbit anti-CEP290 (800 338 9579 ...
• PKC-alpha promotes phosphorylation of KRAS suppressing its oncogenic properties

  Tejashree Joglekar, et al., bioRxiv - Cancer Biology 2022

  Quote: Prostratin (CAS 60857-08-1) was purchased from Santa Cruz Biotechnology (Cat ...
• Npas4-mediated dopaminergic regulation of fear memory states

  BumJin Ko, et al., bioRxiv - Neuroscience 2022

  Quote: ... and goat anti-Drd4 (1:20, sc-31481, Santa Cruz) antibodies were used as primary antibodies ...
• Microglial colonisation of the developing brain is facilitated by clonal expansion of highly proliferative progenitors and follows an allometric scaling

  Liam Barry-Carroll, et al., bioRxiv - Neuroscience 2022

  Quote: ... rabbit anti-Olig2 (Santa Cruz Biotechnology; sc-48817; 1:500), rabbit anti-PU.1 (Cell Signalling Technology ...
• Caspase-mediated regulation and cellular heterogeneity of the cGAS/STING pathway in Kaposi’s sarcoma-associated herpesvirus infection

  Tate Tabtieng, et al., bioRxiv - Microbiology 2022

  Quote: ... Anti-MAVS (sc-166583, 1:1000 dilution; Santa Cruz Biotechnology) was diluted in 0.5% milk in phosphate-buffered saline with 0.1% Tween 20 (PBST ...
• Optogenetic manipulation of Gq- and Gi/o-coupled receptor signaling in neurons and heart muscle cells

  Hanako Hagio, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-Myc tag (MT) antibody (1:500, mouse, Santa Cruz Biotechnology ...
• Zinc-finger protein 518 plays a crucial role in pericentromeric heterochromatin formation by linking satellite DNA to heterochromatin

  Shinya Ohta, et al., bioRxiv - Cell Biology 2022

  Quote: ... mouse anti-GST (1:200, #sc-138, Santa Cruz Biotechnology), rabbit anti-HP1α (1:1,000 ...
• Microglia and astrocytes differentially endocytose exosomes facilitating alpha-Synuclein endolysosomal sorting

  M. Pantazopoulou, et al., bioRxiv - Neuroscience 2022

  Quote: ... and mouse monoclonal D10 (Santa Cruz, sc-515879, 1/1000).
• Dysregulated SASS6 expression promotes increased ciliogenesis and cell invasion phenotypes

  Eleanor Hargreaves, et al., bioRxiv - Cell Biology 2024

  Quote: ... Mouse anti-γ-tubulin (1:500; Santa Cruz Biotechnology, Inc.) and mouse anti-α-tubulin (1:2000 ...
• KAT8 compound inhibition inhibits the initial steps of PINK1-dependant mitophagy

  Capucine de Talhouët, et al., bioRxiv - Neuroscience 2024

  Quote: ... mouse anti TOM20 (Santa Cruz, sc-11415, RRID:AB_2207533, 1:1000), mouse anti GAPDH (Abcam ...
• Structural dynamics of the active HER4 and HER2/HER4 complexes is finely tuned by different growth factors and glycosylation

  Raphael Trenker, et al., bioRxiv - Biochemistry 2024

  Quote: ... mouse anti-ý-Actin (Santa Cruz Biotechnology, sc047778, 1:1000), anti-rabbit IgG HRP-linked antibody (Cell Signaling ...
• Identification and characterization of nanobodies acting as molecular chaperones for glucocerebrosidase through a novel allosteric mechanism

  Thomas Dal Maso, et al., bioRxiv - Biochemistry 2024

  Quote: ... mouse anti-LAMP1(1:400, sc-20011 Santa Cruz Biotechnology), anti-FLAG HRP (1:1000 ...
• Disordered regions and folded modules in CAF-1 promote histone deposition in S. pombe

  Fouad Ouasti, et al., bioRxiv - Biochemistry 2023

  Quote: ... and anti-PCNA antibody (Santa Cruz sc-8349, 1:500).
• Mechanical activation of TWIK-related potassium channel by nanoscopic movement and rapid second messenger signaling

  E. Nicholas Petersen, et al., bioRxiv - Neuroscience 2023

  Quote: ... Primary antibody (PLD2, Cell Signaling #13891; TREK-1, Santa Cruz #sc-50412 ...
• Cyborg islets: implanted flexible electronics reveal principles of human islet electrical maturation

  Qiang Li, et al., bioRxiv - Bioengineering 2024

  Quote: ... Mouse anti-GCG (SC-514592, Santa Cruz Biotech. 1:300); and Mouse anti-CD44 (ab6124 ...
• Stably-Inverted Apical-Out Human Upper Airway Organoids for SARS-CoV-2 Infection and Therapeutic Testing

  Ji-Hoon Lee, et al., bioRxiv - Bioengineering 2024

  Quote: mouse anti-MUC5AC (Santa Cruz Biotechnology, sc-21701; 1:50)
• Stably-Inverted Apical-Out Human Upper Airway Organoids for SARS-CoV-2 Infection and Therapeutic Testing

  Ji-Hoon Lee, et al., bioRxiv - Bioengineering 2024

  Quote: mouse anti-TMPRSS2 (Santa Cruz Biotechnology, sc-515727; 1:50)
• Stably-Inverted Apical-Out Human Upper Airway Organoids for SARS-CoV-2 Infection and Therapeutic Testing

  Ji-Hoon Lee, et al., bioRxiv - Bioengineering 2024

  Quote: rat anti-ITGα6 (Santa Cruz Biotechnology, sc-19622; 1:50)
• Neuronal substance-P drives breast cancer growth and metastasis via an extracellular RNA-TLR7 axis

  Veena Padmanaban, et al., bioRxiv - Cancer Biology 2024

  Quote: ... mouse HSP-60 (1:1000; Santa Cruz Biotechnology, sc-13115), and rabbit TACR1 (1:1000 ...
• Allelic DNA synthesis followed by template switching underlies BRCA1-linked tandem duplication

  Zhi-Cheng Huang, et al., bioRxiv - Cancer Biology 2024

  Quote: ... from Abcam and anti-γH2AX (sc-517348, 1:200) from Santa Cruz and with Alexa Fluor 488-conjugated secondary antibodies (#111-545-003 ...
• αKG-mediated carnitine synthesis promotes homologous recombination via histone acetylation

  Apoorva Uboveja, et al., bioRxiv - Cancer Biology 2024

  Quote: ... mouse BRCA1 (Santa Cruz biotechnology, Cat#sc-6954, 1:500). Secondary antibodies ...
• Hypoxia and TNF-alpha modulate extracellular vesicle release from human induced pluripotent stem cell-derived cardiomyocytes

  Margarida Viola, et al., bioRxiv - Cell Biology 2024

  Quote: ... and anti-Tomm20 (rabbit, Santa Cruz, sc-11415, 1:300). Both blocking and primary antibody incubations were done for 1 hour at room temperature or overnight at 4°C ...
• High-dimensional mass cytometry reveals stemness state heterogeneity in pancreatic ductal adenocarcinoma

  Egle-Helene Ervin, et al., bioRxiv - Cancer Biology 2024

  Quote: ... and treated with Benzonase nuclease (1:10,000, Santa Cruz Biotechnology) for 5 min at room temperature ...
• FTO-mediated m6A demethylation of ULK1 mRNA promotes autophagy and activation of hepatic stellate cells in liver fibrosis

  Tingjuan Huang, et al., bioRxiv - Molecular Biology 2024

  Quote: ... FTO (sc-271713 1:500,) was obtained from Santa Cruz.
• In vitro reconstitution reveals requirement of Nek2a and cyclin A2 for Wapl-dependent removal of cohesin from prophase chromatin

  Susanne Hellmuth, Olaf Stemmann, bioRxiv - Cell Biology 2024

  Quote: ... mouse anti-sororin (1:1,000; sc-365319, Santa Cruz Biotechnology), rabbit anti-sororin (1.7 µg/ml ...
• In vitro reconstitution reveals requirement of Nek2a and cyclin A2 for Wapl-dependent removal of cohesin from prophase chromatin

  Susanne Hellmuth, Olaf Stemmann, bioRxiv - Cell Biology 2024

  Quote: ... mouse anti-cyclin A2 (1:200; 46B11, Santa Cruz Biotechnology), mouse anti-Nek2 (1:600 ...
• Metabolic and age-associated epigenetic barriers during direct reprogramming of mouse fibroblasts into induced cardiomyocytes

  Francisco Santos, et al., bioRxiv - Cell Biology 2024

  Quote: ... mouse anti-PINK1 (Santa Cruz Biotechnology, sc-517353, 1:500), rabbit anti-p62 (Cell Signaling 5114 ...
• Single-cell RNA sequencing of iPSC-derived brain organoids reveals Treponema pallidum infection inhibiting neurodevelopment

  Qiu-Yan Xu, et al., bioRxiv - Neuroscience 2024

  Quote: ... and anti-HOXA5 (mouse, 1:100, Santa cruz, sc-365784). On the following day ...
• Human immunodeficiency virus-1 induces and targets host genomic R-loops for viral genome integration

  Kiwon Park, et al., bioRxiv - Molecular Biology 2024

  Quote: ... monoclonal mouse anti-HIV-1 Integrase (Santa Cruz, sc-69721), rabbit anti-LaminA/C antibody (Cell Signaling ...
• A small molecule inhibitor Mirin prevents TOP3A-dependent mtDNA breakage and segregation

  Koit Aasumets, et al., bioRxiv - Molecular Biology 2024

  Quote: ... rabbit anti-TOMM40 (1:1000; sc-11414; Santa Cruz Biotech.), mouse anti-GAPDH (1:10000 ...
• Roles of TYRO3 Family Receptors in Germ Cell Development During Mouse Testis Formation

  Zhenhua Ming, et al., bioRxiv - Developmental Biology 2024

  Quote: ... anti-AMH mouse monoclonal (sc-166752, Santa Cruz, 1:100), anti-Laminin rabbit polyclonal (L9393 ...
• A RALF-Brassinosteroid morpho-signaling circuit regulates Arabidopsis hypocotyl cell shape

  David Biermann, et al., bioRxiv - Plant Biology 2024

  Quote: ... α-GFP-HRP (1:5000, sc-9996-HRP, Santa Cruz), α-GFP (1:5000 ...
• Profound synthetic lethality between SMARCAL1 and FANCM

  Sumin Feng, et al., bioRxiv - Molecular Biology 2024

  Quote: ... mouse anti-CIP2A (1:500 for IF; Santa Cruz, sc80659), rat anti-FLAG (1:1000 for IF ...
• Loss of CLN3 in microglia leads to impaired lipid metabolism and myelin turnover

  Seda Yasa, et al., bioRxiv - Neuroscience 2024

  Quote: ... anti-actin (WB: 1:1000, Santa Cruz Biotech sc-81178), anti-subunit c (IF ...
• A human papillomavirus 16 E2-TopBP1 dependent SIRT1-p300 acetylation switch regulates mitotic viral and human protein levels

  Apurva T. Prabhakar, et al., bioRxiv - Molecular Biology 2024

  Quote: ... anti-Top1 1:200 (Santa Cruz; catalog no. sc-32736), anti-p53 1:1,000 (Thermo Fisher ...
• SFRP1 upregulation causes hippocampal synaptic dysfunction and memory impairment

  Guadalupe Pereyra, et al., bioRxiv - Neuroscience 2024

  Quote: ... mouse anti-GAPDH (1:5000, Santa Cruz Biotechnology #sc-32233), sheep anti-Nrxn3 (1:1000 ...
• Cellular Modeling of CLN6 with IPSC-derived Neurons and Glia

  Maria Gabriela Otero, et al., bioRxiv - Neuroscience 2024

  Quote: Primary antibodies: OLIG2 (1:100, Santa Cruz Biotechnology, Dallas, TX), NKX2.2 (1:200 ...
• Metabolic control of adaptive β-cell proliferation by the protein deacetylase SIRT2

  Matthew Wortham, et al., bioRxiv - Physiology 2024

  Quote: ... goat-anti-glucagon (Santa Cruz Biotechnology SC-7780, 1:1000), rabbit-anti-γH2AX (Cell Signaling 2577 ...
• Airway succinate chemosensing induces CFTR-dependent anion secretion and mucus clearance which is impaired in cystic fibrosis

  Tábata Apablaza, et al., bioRxiv - Physiology 2024

  Quote: ... 1:200 anti-alpha tubulin (Santa Cruz, cat#sc-5286) or 1:100 anti-NBCe1 (Alomone ...
• Identification of a myofibroblast differentiation program during neonatal lung development

  Yongjun Yin, et al., bioRxiv - Developmental Biology 2023

  Quote: ... rabbit anti-PDGFRA (1:100, sc-338, Santa Cruz Biotechnology), chicken anti-GFP (1:200 ...
• Identification of a myofibroblast differentiation program during neonatal lung development

  Yongjun Yin, et al., bioRxiv - Developmental Biology 2023

  Quote: ... mouse anti-LEF1 (1:100, SC-374522, Santa Cruz Biotechnology), rabbit anti-PDGFRA (1:100 ...
• Expression of the transcription factor Isl1 in dopaminergic neurons of the mouse forebrain

  Adriana C. Camarano, et al., bioRxiv - Developmental Biology 2023

  Quote: ... goat anti-Brn2 (1:250; C-20, Santa Cruz Biotechnology); goat anti-Lhx1 (1:500 ...
• Expression of the transcription factor Isl1 in dopaminergic neurons of the mouse forebrain

  Adriana C. Camarano, et al., bioRxiv - Developmental Biology 2023

  Quote: ... goat anti-Lhx1 (1:500, sc-19341, Santa Cruz Biotechnology); rabbit anti-Pax6 (1:500 ...
• Interactors of sacsin’s DNAJ domain identify function in organellar transport and membrane composition relevant to ARSACS pathogenesis

  Alexandre M. Paré, et al., bioRxiv - Cell Biology 2024

  Quote: ... mouse monoclonal anti-myc (A14, Santa Cruz Biotechnology, 1:400), and mouse monoclonal anti-GAPDH ...
• Rapid turnover of CTLA4 is associated with a complex architecture of reversible ubiquitylation

  Pei Yee Tey, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-ALIX (Santa Cruz Biotechnology, sc-53540, WB 1:1000), anti-Syntenin 1 (Novus Biologicals ...
• Tethering NDC80-NUF2 to microparticles is sufficient to enable their biorientation in the spindle

  Kohei Asai, Yuanzhuo Zhou, Tomoya S. Kitajima, bioRxiv - Cell Biology 2024

  Quote: ... rabbit anti-PRC1 (sc-8356, Santa Cruz Biotechnology; 1:100), rabbit anti-CENP-C (gift from Dr ...
• HemK2 functions for sufficient protein synthesis and RNA stability through eRF1 methylation during Drosophila oogenesis

  Fengmei Xu, et al., bioRxiv - Developmental Biology 2024

  Quote: ... mouse anti-Tubulin (Santa Cruz [DM1A], sc-32293, 1:3,000), rabbit anti-HA (Cell Signaling Technology [C29F4] ...