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4851 - 4900 of 8862 citations for 6 1 4 dioxa 8 azaspiro 4.5 decan 8 yl 3 hydroxy 2 iminopyrimidin 4 amine since 2019

• Brain-wide mapping of neuronal architecture controlling torpor

  Hiroshi Yamaguchi, et al., bioRxiv - Neuroscience 2023

  Quote: ... goat anti-cFos (1:500, Santa Cruz #sc-52G), Alexa Fluor 594 donkey anti-rabbit IgG (1:1000 ...
• OGG1 and MUTYH repair activities promote telomeric 8-oxoguanine induced cellular senescence

  Mariarosaria De Rosa, et al., bioRxiv - Molecular Biology 2023

  Quote: ... Cyclin A (Santa Cruz sc-271682; 1:500 WB).
• The RNA helicase DDX1 associates with the nuclear RNA exosome and modulates R-loops

  Julia L. de Amorim, et al., bioRxiv - Biochemistry 2023

  Quote: ... B23 (mouse monoclonal; Santa Cruz sc-271737; 1:200), DDX1 (rabbit polyclonal ...
• PAK1-dependant mechanotransduction enables myofibroblast nuclear adaptation and chromatin organisation during fibrosis

  Elliot Jokl, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-YAP (Sc-271134, Santa Cruz, dilution: 1:1000), anti-PMYL9 (#3671P ...
• Ganglioside GD3 regulates neural stem cell quiescence and controls postnatal neurogenesis

  Takahiro Fuchigami, Yutaka Itokazu, Robert K. Yu, bioRxiv - Neuroscience 2023

  Quote: ... mouse anti-DCX antibody (1:50, Santa Cruz, #sc271390), rabbit anti-NeuN antibody (1:100 ...
• Self-organization, quality control, and preclinical studies of human iPSC-derived retinal sheets for tissue-transplantation therapy

  Kenji Watari, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-S-opsin (goat; 1:1000; Santa Cruz Biotechnology), anti-S-opsin (rabbit ...
• Self-organization, quality control, and preclinical studies of human iPSC-derived retinal sheets for tissue-transplantation therapy

  Kenji Watari, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-S-opsin (rabbit; 1:500; Santa Cruz Biotechnology), anti-L/M-opsin (rabbit ...
• The phospho-regulated amphiphysin/endophilin interaction is required for synaptic vesicle endocytosis

  Christiana Kontaxi, Michael A. Cousin, bioRxiv - Neuroscience 2023

  Quote: ... goat Dyn1 (1:500; Santa Cruz Biotechnology, sc-6402), goat syndapin 1 (1:1000 ...
• Mechanistic model-driven exometabolomic characterisation of human dopaminergic neuronal metabolism

  German Preciat, et al., bioRxiv - Systems Biology 2022

  Quote: ... rabbit anti-TH (1:1000, Santa Cruz biotechnology, Germany) and chicken anti-GFAP (1:1000 ...
• A comparative study of in vitro air-liquid interface culture models of the human airway epithelium evaluating cellular heterogeneity and gene expression at single cell resolution

  Rachel A. Prescott, et al., bioRxiv - Cell Biology 2023

  Quote: ... α-CC10 diluted 1:400 (cat. No. 365992, Santa Cruz), α-MUC5B diluted 1:2000 (cat ...
• Mice with renal-specific alterations of stem cell-associated signaling develop symptoms of chronic kidney disease but surprisingly no tumors

  Adam Myszczyszyn, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse anti-p53 (1:100, Santa Cruz, sc-126) and mouse anti-p21 (1:100 ...
• Defining the structure, signals, and cellular elements of the gastric mesenchymal niche

  Elisa Manieri, et al., bioRxiv - Cell Biology 2023

  Quote: ... and Somatostatin (Santa Cruz Biotechnology, sc-55565, 1:100).
• COL7A1 expression improves prognosis prediction for patients with clear cell renal cell carcinoma atop of stage

  Dzenis Koca, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Antibodies used: COL7A1 (Santa Cruz Technologies #sc33710 ; 1/1000e) and GAPDH (Life technologies #AM4300 ...
• Signaling protein abundance modulates the strength of the Spindle Assembly Checkpoint

  Chu Chen, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-CDC20 (Santa Cruz Biotechnology sc-13162, 1 : 200), anti-BUB3 (Sigma-Aldrich B7811 ...
• Partial in vivo reprogramming enables injury-free intestinal regeneration via autonomous Ptgs1 induction

  Jumee Kim, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse anti-Cox2 (Santa cruz, sc-19999, 1:100), and rabbit anti-Dclk1(Abcam ...
• Partial in vivo reprogramming enables injury-free intestinal regeneration via autonomous Ptgs1 induction

  Jumee Kim, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse anti-Cox1 (Santa cruz, sc-19998, 1:100), mouse anti-Cox2 (Santa cruz ...
• Mice with renal-specific alterations of stem cell-associated signaling develop symptoms of chronic kidney disease but surprisingly no tumors

  Adam Myszczyszyn, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse anti-MDR1 (1:50, Santa Cruz, sc-55510) and mouse anti-AQP3 (1:50 ...
• Identification of a mitochondrial targeting sequence in cathepsin D and its localization in mitochondria

  Naoki Ikari, Hirofumi Arakawa, bioRxiv - Cell Biology 2023

  Quote: ... anti-TOMM20 (1:100, sc-17764, Santa Cruz Biotechnology) or anti-cytochrome c (1:100 ...
• Early mitochondrial dysfunction proceeds neuroinflammation, synaptic alteration, and autophagy impairment in hippocampus of App knock-in Alzheimer mouse models

  Luana Naia, et al., bioRxiv - Neuroscience 2023

  Quote: ... PDH (1:1,000) (Santa Cruz, Cat. no. sc-377092), IDE (1:900 ...
• An O-GlcNAc transferase pathogenic variant that affects pluripotent stem cell self-renewal

  Michaela Omelková, et al., bioRxiv - Molecular Biology 2023

  Quote: ... Sox17 (Santa Cruz, catalogue number sc-130259, 1:1000) and Brachyury (D10 ...
• Su(var)3-9 mediates age-dependent increase in H3K9 methylation on TDP-43 promoter triggering neurodegeneration

  Marta Marzullo, et al., bioRxiv - Molecular Biology 2023

  Quote: ... anti-actin-HRP-conjugated (1:5000, Santa Cruz Biotechnology). These primary antibodies were detected using HRP conjugated anti-mouse and anti-rabbit IgGs and the ECL detection kit (all from GE Healthcare) ...
• Ciliary ARL13B inhibits developmental kidney cystogenesis in mouse

  Robert E. Van Sciver, et al., bioRxiv - Developmental Biology 2023

  Quote: ... mouse anti-THP (1:250, Santa Cruz, sc-271022). Lectins used were fluorescein conjugated Lotus tetragonolobus lectin (1:300 ...
• The activity of engrailed imaginal disc enhancers is modulated epigenetically by chromatin and autoregulation

  Yuzhong Cheng, Fountane Chan, Judith A. Kassis, bioRxiv - Developmental Biology 2023

  Quote: ... rabbit anti-EN (1:500, Santa Cruz Biotechnology, Inc.), anti-HA.11 (1:1000 ...
• DTX3L and USP28 fine-tune DNA double strand repair through mutual regulation of their protein levels

  Yashwanth Ashok, et al., bioRxiv - Biochemistry 2023

  Quote: ... HA-Tag (F-7) (#sc7392; 1:1000; Santa Cruz), and against α-tubulin (clone B-5-1-2 ...
• Transcriptional changes consistent with altered neuronal differentiation, angiogenesis, and tumor plasticity induced in human subpallial telencephalic organoid-glioblastoma chimeras

  Simone Chiola, et al., bioRxiv - Cancer Biology 2023

  Quote: ... mouse anti-SOX2 (Santa cruz, sc-365823, 1:200), rabbit anti-RFP (Evrogen ...
• Calcium-permeable AMPA receptors govern PV neuron feature selectivity

  Ingie Hong, et al., bioRxiv - Neuroscience 2023

  Quote: ... mouse anti-CaMKIIα (1:1000, sc-32288, Santa Cruz), rabbit anti-GluA1 (1:1000 ...
• Regulation of Oocyte Meiotic Maturation: Unraveling the Interplay between PKA Inhibition and Cdk1 Activation

  Martina Santoni, et al., bioRxiv - Cell Biology 2023

  Quote: ... Mos (1:500, rabbit, Santa Cruz Biotechnology Sc-86), pMAPK (1:2000 ...
• Preserved striatal innervation and motor function despite severe loss of nigral dopamine neurons following mitochondrial dysfunction induced by mtDNA mutations

  Thomas Paß, et al., bioRxiv - Neuroscience 2023

  Quote: ... monoclonal α-D2R (1:200, Santa Cruz, sc-5303), monoclonal α-MAO-A (1:1,000 ...
• Preserved striatal innervation and motor function despite severe loss of nigral dopamine neurons following mitochondrial dysfunction induced by mtDNA mutations

  Thomas Paß, et al., bioRxiv - Neuroscience 2023

  Quote: ... monoclonal α-D1R (1:200; Santa Cruz, sc-33660), monoclonal α-D2R (1:200 ...
• Preserved striatal innervation and motor function despite severe loss of nigral dopamine neurons following mitochondrial dysfunction induced by mtDNA mutations

  Thomas Paß, et al., bioRxiv - Neuroscience 2023

  Quote: ... monoclonal α-TH (1:500; Santa Cruz, sc-25269) and polyclonal α-GFP (1:1,000 ...
• PolyGR and polyPR knock-in mice reveal a conserved neuroprotective extracellular matrix signature in C9orf72 ALS/FTD neurons

  Carmelo Milioto, et al., bioRxiv - Neuroscience 2023

  Quote: ... Calnexin (sc-6465, Santa Cruz Biotechnology; 1:1000 dilution). After 3 washes in PBS-T ...
• DNAJB1-PRKACA fusion protein-regulated LINC00473 promotes tumor growth and alters mitochondrial fitness in fibrolamellar carcinoma

  Rosanna K. Ma, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Vinculin (1:1000 dilution, Santa Cruz Biotechnology, sc-73614), mouse IgG secondary antibody (1:2000 ...
• DNAJB1-PRKACA fusion protein-regulated LINC00473 promotes tumor growth and alters mitochondrial fitness in fibrolamellar carcinoma

  Rosanna K. Ma, et al., bioRxiv - Cancer Biology 2023

  Quote: ... HSP40 (1:1000 dilution, Santa Cruz Biotechnology, sc-398766), Vinculin (1:1000 dilution ...
• Prenatal SARS-CoV-2 infection alters postpartum human milk-derived extracellular vesicles

  Somchai Chutipongtanate, et al., bioRxiv - Systems Biology 2023

  Quote: ... anti-CD9 (1:1000) (#sc-13118; Santa Cruz Biotechnology), anti-Alix (1:1000 ...
• Chronic intermittent hypoxia induced-dysmetabolism is associated with hepatic oxidative stress, mitochondrial dysfunction and inflammation

  Joana L. Fernandes, et al., bioRxiv - Physiology 2023

  Quote: ... arginase I (1:500, Santa Cruz Biotechnology, Madrid, Spain), interleukin 6 receptor (IL6R ...
• A Novel, Uniquely Efficacious Type of CFTR Corrector with Complementary Mode of Action

  Valentina Marchesin, et al., bioRxiv - Pharmacology and Toxicology 2023

  Quote: ... or mouse anti-ubiquitin (Santa Cruz, #P4D1, 1:500) or rabbit-anti-ubiquitin (Abcam ...
• Lineage-specific intolerance to oncogenic drivers restricts histological transformation

  Eric E. Gardner, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-Cyp2f2-A488 (Santa Cruz; #sc-374540; 1:500), anti-BrdU (eBioscience #14-5071-82 ...
• Weak neuronal glycolysis sustains cognition and organismal fitness

  Daniel Jimenez-Blasco, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-NDUFS1 (1/500) (sc-50132; Santa Cruz Biotechnology), anti-NDUFA9 (1/1,000 ...
• Serine ubiquitination of p62 regulates Nrf2 dependent redox homeostasis

  Rukmini Mukherjee, et al., bioRxiv - Cell Biology 2023

  Quote: ... Nrf2 antibody (Santa Cruz biotechnology, sc-365949; 1:1000), GAPDH (cat ...
• Tafazzin Mediates Tamoxifen Resistance by Regulating Cellular Phospholipid Composition in ER-Positive Breast Cancer

  Xuan Li, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-Tafazzin (1:100, Santa Cruz, Catalog # sc-365810), anti-GREB1 (1:1,000 ...
• Preserved striatal innervation and motor function despite severe loss of nigral dopamine neurons following mitochondrial dysfunction induced by mtDNA mutations

  Thomas Paß, et al., bioRxiv - Neuroscience 2023

  Quote: ... monoclonal α-TH (1:500; Santa Cruz, sc-25269), monoclonal α-mtCOI (1:1,000 ...
• A transient modified mRNA encoding Myc and Cyclin T1 induces cardiac regeneration and improves cardiac function after myocardial injury

  Aleksandra Boikova, et al., bioRxiv - Molecular Biology 2023

  Quote: ... and (CT3, Santa Cruz Biotechnology, sc-20025, 1:50). phospho-Histone H3 (Ser10 ...
• BMP7 promotes cardiomyocyte regeneration

  Chiara Bongiovanni, et al., bioRxiv - Molecular Biology 2023

  Quote: ... and anti-ERK2 (1:50, sc-1647, Santa Cruz) were used to analyse BMP7 downstream signalling after myocardial infarction.
• Human skeletal muscle organoids model fetal myogenesis and sustain uncommitted PAX7 myogenic progenitors

  Lampros Mavrommatis, et al., bioRxiv - Bioengineering 2023

  Quote: ... anti-MYOD1 (Santa Cruz Biotechnologies, clone 5.8A, 1:200), anti-PRDM16 (Abcam ...
• Systemic Lupus Erythematosus Serum Stimulation of Human Intestinal Organoids Induces Changes in Goblet Cell Differentiation and Mitochondrial Fitness

  Inga Viktoria Hensel, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-MUC2 (1:200; Santa Cruz Biotechnology, sc-515032) or anti-CHGA (1:100 ...
• Phosphorylation controls spatial and temporal activities of motor-PRC1 complexes to complete mitosis

  Agata Gluszek-Kustusz, et al., bioRxiv - Biochemistry 2023

  Quote: ... and PRC1 (sc-376983, Santa Cruz, 1:200 mouse) (McHugh et al. ...
• 3D Co-culture Model on the Role of Vimentin in Notch Signaling and Vascularization

  Khalil Dayekh, Kibret Mequanint, bioRxiv - Bioengineering 2023

  Quote: ... and GAPDH (1:1000) primary antibodies (Santa Cruz Biotech) diluted in 5% BSA in PBS-T overnight at 4° C ...
• Cystin is required for maintaining fibrocystin (FPC) levels and safeguarding proteome integrity in mouse renal epithelial cells A mechanistic connection between the kidney defects in cpk mice and human ARPKD

  Yiming Zhang, et al., bioRxiv - Cell Biology 2023

  Quote: ... ENaCα (goat pAb, Santa Cruz; sc-22239; 1:200), LAMP1 (mouse mAb ...
• Lethal giant larvae gene family (Llgl1 and Llgl2) functions as a tumor suppressor in mouse skin epidermis

  Victor M. Bii, et al., bioRxiv - Cancer Biology 2023

  Quote: ... mouse anti-aPKC (1:1000, Santa Cruz, sc-17781); rabbit anti-p-IKKα/β (1:500 ...
• Impaired Barrier Integrity of the Skeletal Muscle Vascular Endothelium Drives Progression of Cancer Cachexia

  Young-Mee Kim, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Actin (Santa Cruz, sc-517582 HRP, 1:1000 dilution), or VE-cadherin (Cayman #160840 ...