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4651 - 4700 of 8862 citations for 6 1 4 dioxa 8 azaspiro 4.5 decan 8 yl 3 hydroxy 2 iminopyrimidin 4 amine since 2019

• Genetic dissection of glutamatergic neuron subpopulations and developmental trajectories in the cerebral cortex

  Katherine S. Matho, et al., bioRxiv - Neuroscience 2021

  Quote: ... and anti-Tle4 (1:300, Santa Cruz sc-365406) were used.
• The comprehensive roadmaps of reprogramming and transformation unveiled antagonistic roles for bHLH transcription factors in the control of cellular plasticity

  A. Huyghe, et al., bioRxiv - Cell Biology 2020

  Quote: ... mouse anti-SSEA1 (sc-101462, Santa Cruz, 1:1000), mouse anti-CDH1 (610181 ...
• DEPDC1/ EEF1A1 complex promotes the progression of human osteosarcoma via downregulation of FOXO3a

  Lin Shen, et al., bioRxiv - Cell Biology 2021

  Quote: ... or anti-HIS-antibody (1:300; Santa Cruz Biotechnology) for immunoprecipitation.
• Identifying SARS-CoV-2 entry inhibitors through drug repurposing screens of SARS-S and MERS-S pseudotyped particles

  Catherine Z. Chen, et al., bioRxiv - Pharmacology and Toxicology 2020

  Quote: ... 1:1000 primary mouse-anti-luciferase antibody (Santa Cruz) was added ...
• Methylation-directed Acetylation of Histone H3 Regulates Developmental Sensitivity to Histone Deacetylase Inhibition

  Li-Yao Huang, Duen-Wei Hsu, Catherine Pears, bioRxiv - Pharmacology and Toxicology 2020

  Quote: ... β-actin (1:3000, Santa Cruz Biotechnology #sc-47778), FLAG (1:3000 ...
• MTOR promotes basal cell carcinoma growth through atypical PKC

  Rachel Y. Chow, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Gli1 (rabbit, Santa Cruz Biotechnology sc-20687, 1:500), Gli1 p-T304 (rabbit ...
• MTOR promotes basal cell carcinoma growth through atypical PKC

  Rachel Y. Chow, et al., bioRxiv - Cancer Biology 2020

  Quote: ... aPKC (rabbit, Santa Cruz Biotechnology sc-216, 1:500), aPKC p-T410 (rabbit ...
• PLEKHA5, PLEKHA6 and PLEKHA7 bind to PDZD11 to target the Menkes ATPase ATP7A to the cell periphery and regulate copper homeostasis

  Sophie Sluysmans, et al., bioRxiv - Cell Biology 2021

  Quote: ... rabbit HA (sc-805, Santa Cruz, IF: 1/100); mouse myc (9E10 ...
• DNA damage signaling regulates cohesin stabilization and promotes meiotic chromosome axis morphogenesis

  Zhouliang Yu, Abby F. Dernburg, bioRxiv - Cell Biology 2021

  Quote: ... mouse anti-WAPL (1:500, Santa Cruz sc-365189), rabbit anti-γH2A.X antibody (1:500 ...
• Poly(ADP-ribose) potentiates ZAP antiviral activity

  Guangai Xue, et al., bioRxiv - Microbiology 2020

  Quote: ... mouse anti-HA [F-7] (1:3000; Santa Cruz), mouse anti-β-Actin [C4] (1:3000 ...
• Notch signaling determines cell-fate specification of the two main types of vomeronasal neurons of rodents

  Raghu Ram Katreddi, et al., bioRxiv - Developmental Biology 2021

  Quote: ... *Mouse anti-Meis2 (1:500, sc-515470, Santa Cruz), Rabbit anti-Meis2 (*with antigen retrieval 1:1000 and without antigen retrieval 1:500 ...
• The versatility of Ascorbate Peroxidase-aided mapping uncovers insights of the nuclear lamina interactions and function

  Joseph R. Tran, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-Emerin (1:5000, Santa Cruz, #sc-15378), mouse anti-SC-35 (1:2500 ...
• A Cytoskeletal Function for PBRM1 Reading Methylated Microtubules

  Menuka Karki, et al., bioRxiv - Cell Biology 2020

  Quote: ... DM1A (Santa Cruz, cat# sc32293, 1:4,000 IB, IF), GFP (Santa Cruz ...
• IFT20 is critical for early chondrogenesis during endochondral ossification

  Hiroyuki Yamaguchi, et al., bioRxiv - Developmental Biology 2021

  Quote: ... anti-SOX9 (Santa cruz biotechnology; sc-20095, 1:100), anti-phospho ERK1/2 (Cell signaling technology ...
• Acetylated microtubules are required for maintenance of the barrier between two adjacent tissues

  Matthew Antel, et al., bioRxiv - Developmental Biology 2021

  Quote: ... and anti-rabbit Vasa (1:200) (Santa Cruz Biotechnology).
• The E3 Ubiquitin Ligase Mindbomb1 controls zebrafish Planar Cell Polarity

  Vishnu Muraleedharan Saraswathy, et al., bioRxiv - Developmental Biology 2021

  Quote: ... Mouse@c-Myc9E10 (Santa Cruz sc-40, 1:250). Secondary antibodies Goat@Rat-Alexa488 (Invitrogen ...
• Ankylosis homologue mediates cellular efflux of ATP, not pyrophosphate

  Flora Szeri, et al., bioRxiv - Biochemistry 2021

  Quote: ... 1 μmol/L APS (Santa Cruz Biotechnology, Dallas, TX), 80 μmol/L MgCl2 and 50 mmol/L HEPES (pH 7.4) ...
• Acyloxyacyl Hydrolase Regulates Microglia-Mediated Pelvic Pain Through Toll-Like Receptor-4

  Afrida Rahman-Enyart, et al., bioRxiv - Neuroscience 2021

  Quote: ... and anti-β-Actin (1:5000; Santa Cruz Biotechnology). After incubation ...
• The E3 ubiquitin ligase HECTD1 contributes to cell cycle progression through an effect on mitosis

  Natalie Vaughan, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-GAPDH (Santa Cruz Laboratory, sc-25779, 1/2,000), phospho-Chk2 Thr68 (Cell Signaling Technology ...
• Engineering RNA viruses with unnatural amino acid to evoke adjustable immune response in mice

  Zhetao Zheng, et al., bioRxiv - Bioengineering 2021

  Quote: ... anti-PylRS antibodies (1:3000, sc-365062, Santa Cruz Biotechnology ...
• Urgent Brain Vascular Regeneration Occurs via Lymphatic Transdifferentiation

  Jingying Chen, et al., bioRxiv - Developmental Biology 2021

  Quote: ... GFP or Venus (1:500, Abcam and Santa Cruz), Dendra2 (1:500 ...
• Reactive oxygen species prevent lysosome coalescence during PIKfyve inhibition

  Golam T. Saffi, et al., bioRxiv - Cell Biology 2021

  Quote: ... Arl8a/b (1:500, clone H8, Santa Cruz Biotechnology), and ATP5A (1:2000 ...
• Genome-Wide CRISPR Screen Identifies Non-Canonical NF-κB Signaling as a Potent Regulator of Density-dependent Proliferation

  Maria Fomicheva, Ian G. Macara, bioRxiv - Cell Biology 2020

  Quote: ... mouse anti-TRAF3 (1:200, Santa Cruz, sc-6933), rabbit anti-UBE2M (1:500 ...
• A quantitative inventory of yeast P body proteins reveals principles of composition and specificity

  Wenmin Xing, et al., bioRxiv - Cell Biology 2020

  Quote: ... and goat-anti-mouse-IgG (1:10,000) (Santa Cruz) were used as secondary antibodies.
• Rabaptin5 targets autophagy to damaged endosomes and SCVs by interaction with FIP200 and ATG16L1

  Valentina Millarte, et al., bioRxiv - Cell Biology 2021

  Quote: ... Mouse anti-ubiquitin (SC-8017, Santa Cruz, 1:500) and mouse anti-ALIX (634502 ...
• The TPLATE complex mediates membrane bending during plant clathrin-mediated endocytosis

  Alexander Johnson, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-CHC 1:1,000 (sc-57684, Santa Cruz Biotechnology), anti-AP2mu2 1:250 (27) ...
• Translational control of polyamine metabolism by CNBP is required for Drosophila locomotor function

  Sonia Coni, et al., bioRxiv - Genetics 2021

  Quote: ... anti-Vinculin mouse (1:1000; Santa Cruz, sc-73614); anti-Tubulin mouse (1:7000 ...
• Translational control of polyamine metabolism by CNBP is required for Drosophila locomotor function

  Sonia Coni, et al., bioRxiv - Genetics 2021

  Quote: ... anti-Actin goat (1:1000; Santa Cruz, sc-1616); anti-ODC rabbit (1:500 ...
• Post-Transcriptional Regulation of Antiviral Gene Expression by N6-Methyladenosine

  Michael J. McFadden, et al., bioRxiv - Immunology 2020

  Quote: ... mouse anti-ISG15 (Santa Cruz sc-166755, 1:5000), rabbit anti-EIF2AK2 (Abcam ab32506 ...
• The cell-cell adhesion protein JAM3 determines nuclear deformability by regulating microtubule organization

  Mar Arias-Garcia, et al., bioRxiv - Cell Biology 2020

  Quote: ... and Mouse anti-YAP/TAZ (Santa Cruz, 1:1000) overnight at 4 °C on a rolling shaker ...
• A more complex basal complex: novel components mapped to the Toxoplasma gondii cytokinesis machinery portray an expanded hierarchy of its assembly and function

  Klemens Engelberg, et al., bioRxiv - Microbiology 2021

  Quote: ... MAb 9E10 α-cMyc (1:50; Santa Cruz Biotechnology), MAb 9B11 α-cMyc Alexa488 (A488 ...
• Anti-inflammatory role of curcumin in Lipopolysaccharide treated A549 cells at global proteome level and on mycobacterial infection

  Suchita Singh, et al., bioRxiv - Biochemistry 2020

  Quote: ... AIFM1 (1:1000, sc-55519, Santa Cruz, CA, USA) and β-actin (1:1000 ...
• Cylindromatosis Drives Synapse Pruning and Weakening by Promoting Macroautophagy through Akt-mTOR Signaling

  Alexis S. Zajicek, et al., bioRxiv - Neuroscience 2021

  Quote: ... Staining: LC3-II (1:200; Santa Cruz, SC-376404), Alexa Fluor 647 Goat anti-Rabbit IgG (1:500 ...
• A translation control module coordinates germline stem cell differentiation with ribosome biogenesis during Drosophila oogenesis

  Elliot T. Martin, et al., bioRxiv - Developmental Biology 2021

  Quote: ... Rabbit anti-CycB 1:200 (Santa Cruz Biotechnology, 25764), Rabbit anti-Fibrillarin 1:200 (Abcam ab5821) ...
• A long-range chromatin interaction regulates SATB homeobox 1 gene expression in trophoblast stem cells

  Wei Yu, et al., bioRxiv - Developmental Biology 2020

  Quote: ... anti-GATA4 (sc-25310, Santa Cruz Biotechnology, 1:2000), anti-FLAG (#14793 ...
• A long-range chromatin interaction regulates SATB homeobox 1 gene expression in trophoblast stem cells

  Wei Yu, et al., bioRxiv - Developmental Biology 2020

  Quote: ... and ELF5 (sc-9645, Santa Cruz Biotechnology, 1:2000). Anti-TUBA (MABT522 ...
• A long-range chromatin interaction regulates SATB homeobox 1 gene expression in trophoblast stem cells

  Wei Yu, et al., bioRxiv - Developmental Biology 2020

  Quote: ... anti-OCT4 (sc-5279, Santa Cruz Biotechnology, 1:2000), anti-GATA4 (sc-25310 ...
• A RIPOR2 in-frame deletion is a frequent and highly penetrant cause of adult-onset hearing loss

  Suzanne E. de Bruijn, et al., bioRxiv - Genetics 2019

  Quote: ... anti-Myc (mouse; 1:500; cat.#9E10; Santa Cruz); anti-GFP (mouse ...
• Huntington’s disease-specific mis-splicing captured by human-mouse intersect-RNA-seq unveils pathogenic effectors and reduced splicing factors

  Ainara Elorza, et al., bioRxiv - Neuroscience 2020

  Quote: ... rabbit anti-U2AF2 (1:500, Santa Cruz, sc-53942), mouse anti-RBFOX1 (1:2000 for mouse and 1:1000 for human samples ...
• A missense in HSF2BP causing Primary Ovarian Insufficiency affects meiotic recombination by its novel interactor C19ORF57/MIDAP

  Natalia Felipe-Medina, et al., bioRxiv - Genetics 2020

  Quote: ... mouse αSYCP3 IgG sc-74569 (1:100, Santa Cruz), rabbit α-SYCP3 serum K921 (provided by Dr ...
• Engineered chimeric T cell receptor fusion construct (TRuC)-expressing T cells prevent translational shutdown in SARS-CoV-2-infected cells

  Ira Godbole, et al., bioRxiv - Bioengineering 2021

  Quote: ... anti-CD3δ (clone F-1, Santa Cruz, #sc-137137,), anti-CD3ε (clone M20 ...
• FTO suppresses STAT3 activation and modulates proinflammatory interferon-stimulated gene expression

  Michael J. McFadden, et al., bioRxiv - Molecular Biology 2021

  Quote: ... mouse anti-ISG15 (Santa Cruz sc-166755, 1:5000), rabbit anti-EIF2AK2 (Abcam ab32506 ...
• Genetic and epigenetic determinants of reactivation of Mecp2 and the inactive X chromosome in neural stem cells

  Hegias Mira-Bontenbal, et al., bioRxiv - Molecular Biology 2021

  Quote: ... goat anti-SOX2 (Santa Cruz, sc-17320, 1:500), rabbit anti-NLuc (kind gift of Promega ...
• MICAL2 acts through Arp3B isoform-specific Arp2/3 complexes to destabilize branched actin networks

  Chiara Galloni, et al., bioRxiv - Cell Biology 2020

  Quote: ... GAPDH monoclonal (Santa Cruz, sc-32233, 1:1000 dilution), Cortactin monoclonal (Millipore ...
• Loss of C9orf72 perturbs the Ran-GTPase gradient and generates compositionally diverse cytoplasmic Importin β-1 granules in motor and cortical neurons in vivo

  Philip McGoldrick, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-RanGAP (Santa Cruz sc-25630, 1:200), mouse anti-Ran-GTPase (BD Biosciences 610340 ...
• Acyloxyacyl Hydrolase Regulates Microglia-Mediated Pelvic Pain Through Toll-Like Receptor-4

  Afrida Rahman-Enyart, et al., bioRxiv - Neuroscience 2021

  Quote: ... anti-AOAH (1:100; Santa Cruz Biotechnology, Dallas, TX), and anti-IL-4 (1:500 ...
• Investigation of USP30 inhibition to enhance Parkin-mediated mitophagy: tools and approaches

  Eliona Tsefou, et al., bioRxiv - Neuroscience 2021

  Quote: ... anti-USP30 (Santa Cruz, sc-515235, 1 in 100), anti-Vinculin (Abcam ...
• Action potential-coupled Rho GTPase signaling drives presynaptic plasticity

  Shataakshi Dube, et al., bioRxiv - Neuroscience 2020

  Quote: ... mouse anti-Myc (Santa Cruz sc-40, 1:250), mouse anti-bassoon (Abcam ab82958 ...
• Targeting of MCL-1 in breast cancer associated fibroblasts reverses their myofibroblastic phenotype and pro-invasive properties

  TL Bonneaud, et al., bioRxiv - Cancer Biology 2021

  Quote: ... TOM20 (1:80, Santa Cruz Biotech., Dallas, TX, USA); Mcl-1 (1:800 ...
• Translational control of polyamine metabolism by CNBP is required for Drosophila locomotor function

  Sonia Coni, et al., bioRxiv - Genetics 2021

  Quote: ... anti-GFP mouse (1:500; Santa Cruz, sc-9996); anti-FLAG HRP (1:1000 ...