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4901 - 4950 of 8862 citations for 6 1 4 dioxa 8 azaspiro 4.5 decan 8 yl 3 hydroxy 2 iminopyrimidin 4 amine since 2019

• Autophagy mediates cancer cell resistance to doxorubicin induced by the Programmed Death 1/Programmed Death Ligand 1 immune checkpoint axis

  Lori Minassian, et al., bioRxiv - Cancer Biology 2023

  Quote: ... rabbit-anti-ERK1 (Santa Cruz sc-94, 1:1000), rabbit anti-α-actinin (Santa Cruz sc-15335 ...
• TTBK2 mutations associated with spinocerebellar ataxia type 11 disrupt peroxisome dynamics and ciliary localization of SHH signaling proteins

  Jesús Muñoz-Estrada, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse anti-SMO (Santa Cruz, sc-166685, 1:500). Specific secondary fluorescent antibodies were used ...
• Identification of a mitochondrial targeting sequence in cathepsin D and its localization in mitochondria

  Naoki Ikari, Hirofumi Arakawa, bioRxiv - Cell Biology 2023

  Quote: ... anti-Golgin97 (1:200, sc-59820, Santa Cruz Biotechnology), anti-beta-actin (1:5000 ...
• Identification of a mitochondrial targeting sequence in cathepsin D and its localization in mitochondria

  Naoki Ikari, Hirofumi Arakawa, bioRxiv - Cell Biology 2023

  Quote: ... anti-TOMM20 (1:250, sc-17764, Santa Cruz Biotechnology), anti-ATP5F1B (1:400 ...
• Identification of a mitochondrial targeting sequence in cathepsin D and its localization in mitochondria

  Naoki Ikari, Hirofumi Arakawa, bioRxiv - Cell Biology 2023

  Quote: ... anti-SEC22B (1:200, sc-101267, Santa Cruz Biotechnology), anti-Golgin97 (1:200 ...
• PARP inhibition and pharmacological ascorbate demonstrate synergy in castration-resistant prostate cancer

  Nicolas Gordon, et al., bioRxiv - Cancer Biology 2023

  Quote: ... CDC2 p34 (1:200, Santa Cruz Biotechnology Sc-54) and Vinculin (1:1000 ...
• Arginine shortage induces replication stress and confers genotoxic resistance by inhibiting histone H4 translation and promoting PCNA polyubiquitination

  Yi-Chang Wang, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-SMARCAL1 (1:1000; Cat# sc-376377, Santa Cruz), anti-ZRANB3 (1:1000 ...
• Arginine shortage induces replication stress and confers genotoxic resistance by inhibiting histone H4 translation and promoting PCNA polyubiquitination

  Yi-Chang Wang, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-PCNA (1:3000, Cat# sc-7907, Santa Cruz), anti-phospho-eIF2α (1:1000 ...
• Arginine shortage induces replication stress and confers genotoxic resistance by inhibiting histone H4 translation and promoting PCNA polyubiquitination

  Yi-Chang Wang, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-SHPRH (1:1000; Cat# sc-514395, Santa Cruz), anti-SMARCAL1 (1:1000 ...
• An intravenous DNA-binding priming agent protects cell-free DNA and improves the sensitivity of liquid biopsies

  Shervin Tabrizi, et al., bioRxiv - Genomics 2023

  Quote: ... 1.BB.27 (cat. sc-73064, Santa Cruz Biotechnology), 3H12 (cat ...
• Natural variation in Prdm9 affecting hybrid sterility phenotypes

  Khawla FN AbuAlia, et al., bioRxiv - Genetics 2023

  Quote: ... SYCP3 (mouse monoclonal antibody, Santa Cruz, #74569, 1:50), yH2AX (ab2893 ...
• MARCH5-dependent NLRP3 ubiquitination is an essential step for NEK7 docking on the mitochondria

  Yeon-Ji Park, et al., bioRxiv - Immunology 2023

  Quote: ... anti-Ub (1:1,000, sc-8017, Santa cruz technology). To detect the release of caspase-1 (p20 ...
• MARCH5-dependent NLRP3 ubiquitination is an essential step for NEK7 docking on the mitochondria

  Yeon-Ji Park, et al., bioRxiv - Immunology 2023

  Quote: ... anti-HA (1:1,000, sc-7392, Santa cruz technology), anti-Ub (1:1,000 ...
• Mutual regulation of transcriptomes between pneumocytes and fibroblasts mediates alveolar regeneration

  Yiwen Yao, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-HOPX (Santa Cruz Biotechnology, sc-398703, 1:100) and anti-CCSP (Merck ...
• Spatial positioning of preimplantation mouse embryo blastomeres is regulated by mTORC1 and 7mG-cap dependent translation at the 8- to 16-cell transition

  Lenka Gahurova, et al., bioRxiv - Developmental Biology 2023

  Quote: ... anti-PRKCZ (Santa Cruz Biotechnology #sc-216; 1:200), and viii ...
• Spatial positioning of preimplantation mouse embryo blastomeres is regulated by mTORC1 and 7mG-cap dependent translation at the 8- to 16-cell transition

  Lenka Gahurova, et al., bioRxiv - Developmental Biology 2023

  Quote: ... anti-PARD6B (Santa Cruz Biotechnology #sc-67393; 1:200), b ...
• Mitochondrial metabolism in Drosophila macrophage-like cells regulates body growth via modulation of cytokine and insulin signaling

  Shrivani Sriskanthadevan-Pirahas, et al., bioRxiv - Developmental Biology 2023

  Quote: ... anti-actin (1:1000, Santa Cruz Biotechnology, # sc-8432), anti-dILP250 (1:500) ...
• Oxidative stress-induced MMP- and γ-secretase-dependent VE-cadherin processing is modulated by the proteasome and BMP9/10

  Caterina Ivaldo, et al., bioRxiv - Cell Biology 2022

  Quote: ... Anti-VE-cadherin (mouse, Santa Cruz Biotechnology, 1:100) and anti-β-catenin (rabbit ...
• CCDC15 localizes to the centriole inner scaffold and regulates centriole integrity and ciliogenesis

  Melis D. Arslanhan, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse anti Cep164 (1:1000, Santa Cruz Biotechnology, sc515403), mouse anti SAS6 (1:1000 ...
• CCDC15 localizes to the centriole inner scaffold and regulates centriole integrity and ciliogenesis

  Melis D. Arslanhan, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse anti rootletin (1:500, Santa Cruz Biotechnology, sc374056), mouse anti glutamylated-tubulin (GT335 ...
• CCDC15 localizes to the centriole inner scaffold and regulates centriole integrity and ciliogenesis

  Melis D. Arslanhan, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse anti SAS6 (1:1000, Santa Cruz Biotechnology, sc81431), mouse anti rootletin (1:500 ...
• The DUSP1 on CaMKII-positive neurons in mPFC mediates adolescent cocaine exposure-induced higher sensitivity to cocaine during adulthood

  Xiaoyan Wei, et al., bioRxiv - Neuroscience 2023

  Quote: ... mouse anti-SOM (1:50, RRID:AB_2271061, Santa Cruz, USA), mouse anti-CaMKIIα (1:100 ...
• Circular RNAs arising from synaptic host genes are modulated by SFPQ RNA-binding protein and increased during human neuronal differentiation

  Michelle Watts, et al., bioRxiv - Neuroscience 2023

  Quote: ... or mouse αTIAL1 (1:10; Santa Cruz sc-398372). The Compass for S.W ...
• Estrogen receptor alpha mutations regulate gene expression and cell growth in breast cancer through microRNAs

  Spencer Arnesen, et al., bioRxiv - Cancer Biology 2023

  Quote: ... ER (Santa Cruz Biotechnology, sc-543, 1:1000 dilution), Beta-Actin (Santa Cruz Biotechnology ...
• Postsynaptic receptors regulate presynaptic transmitter stability through trans-synaptic bridges

  Swetha K. Godavarthi, et al., bioRxiv - Neuroscience 2023

  Quote: ... and CASK (1:200, Santa Cruz Biotechnology, SC-13158). After 3 washes in 1X PBS ...
• Postsynaptic receptors regulate presynaptic transmitter stability through trans-synaptic bridges

  Swetha K. Godavarthi, et al., bioRxiv - Neuroscience 2023

  Quote: ... and CASK (1:500, Santa Cruz Biotechnology, SC-13158). The same blots were re-probed for the loading control actin (1:1000 ...
• SMARCAD1 and TOPBP1 contribute to heterochromatin maintenance at the transition from the 2C-like to the pluripotent state

  Ruben Sebastian-Perez, et al., bioRxiv - Developmental Biology 2023

  Quote: ... mouse anti-OCT4 (1:500; sc-5279, Santa Cruz), rabbit anti-TOPBP1 (1:1000 ...
• Patient-derived tumoroids of advanced high-grade neuroendocrine neoplasms mimic patient chemotherapy responses and guide the design of personalized combination therapies

  Simon L. April-Monn, et al., bioRxiv - Cancer Biology 2022

  Quote: ... BCL-10 (1:1000, Santa Cruz, sc-5273 331.3). Primary antibody incubation lasted 30 min at the specified dilutions ...
• CHI3L1 enhances melanoma lung metastasis via regulation of t cell co-stimulators and CTLA-4/B7 axis

  Bing Ma, et al., bioRxiv - Immunology 2022

  Quote: ... anti-mouse B7-1 (F-7, Santa Cruz Biotechnology) and anti-mouse B7-2 (BU63 ...
• Acute resistance exercise induces mitophagy and mitophagomes on subsarcolemmal clefts in human skeletal muscle: Focus on BNIP3L/NIX40 as a mitophagy flux marker

  F. Díaz-Castro, et al., bioRxiv - Physiology 2023

  Quote: ... p-Drp1ser616 (1:1,000, SC-101270, Santa Cruz Biotechnology), PINK1 (1:1000 ...
• Human Herpesvirus 8 ORF57 protein is able to reduce TDP-43 pathology: Network analysis Identifies Interacting Pathways

  Chelsea J Webber, et al., bioRxiv - Neuroscience 2023

  Quote: ... Anti-eIF3ɳ (Mouse, 1:250 dilution, Santa Cruz #137214), Anti-TDP43 C-terminus (Rabbit ...
• Rational development of a small-molecule activator of CK1γ2 that decreases C99 and beta-amyloid levels

  Victor Hugo Bustos, et al., bioRxiv - Pharmacology and Toxicology 2023

  Quote: ... and antiactin (rabbit polyclonal, 1:1,000; Santa Cruz Biotechnology), anti-LC3 (rabbit polyclonal ...
• Wnt5a-Ror2 signaling activates p62-Nrf2 axis in reactive astrocytes after brain injury

  Mitsuharu Endo, et al., bioRxiv - Molecular Biology 2023

  Quote: ... mouse anti-Pgd (Santa Cruz Biotechnology, 398977, 1:100), rabbit anti-HO-1 (Abcam ...
• RGS6 mediates exercise-induced recovery of hippocampal neurogenesis, learning, and memory in an Alzheimer’s mouse model

  Mackenzie M. Spicer, et al., bioRxiv - Neuroscience 2023

  Quote: ... mouse-anti-DCX (Santa Cruz Sc-271390, 1:200), or mouse-anti-NeuN (Millipore MAB377 ...
• Late gene therapy limits the restoration of retinal function in a mouse model of retinitis pigmentosa

  Miranda L. Scalabrino, et al., bioRxiv - Neuroscience 2023

  Quote: ... PCP2 (1:500, Santa Cruz sc-137064, RRID: AB_2158439), CtBP2 (1:1000 ...
• Arl3 regulates ODA16-mediated intraflagellar transport in motile cilia biogenesis

  Yameng Huang, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-HA (mouse, Santa Cruz, sc-7392, 1:250).
• Allele pairing at Sun1-enriched domains at the nuclear periphery via T1A3 tandem DNA repeats

  Gayan I. Balasooriya, David L. Spector, bioRxiv - Cell Biology 2023

  Quote: ... Biotin antibody (33) 1: 1000 (Santa Cruz, Cat.No. 101339), LaminB1 (1:500 ...
• NRF2 connects Src tyrosine kinase to ferroptosis resistance in glioblastoma

  Claudia Cirotti, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-Lamin (E-1) (sc-376248, Santa Cruz Biotechnology), anti-GAPDH (D16H11 ...
• Structural basis for BIRC6 to balance apoptosis and autophagy

  Shuo-Shuo Liu, et al., bioRxiv - Cell Biology 2022

  Quote: ... Anti-procaspase-9 mouse IgG (1:100, Santa Cruz) and anti-LC3 rabbit IgG (1:100 ...
• RNA-binding protein YBX1 promotes Type H vessels dependent bone formation in an m5C-dependent manner

  Yu-Jue Li, Qi Guo, Wen-Feng Xiao, Ye Xiao, bioRxiv - Molecular Biology 2023

  Quote: ... endomucin (#sc-65495, Santa Cruz Biotechnology, USA, 1:50), Ybx1 (#4202S ...
• RNA-binding protein YBX1 promotes Type H vessels dependent bone formation in an m5C-dependent manner

  Yu-Jue Li, Qi Guo, Wen-Feng Xiao, Ye Xiao, bioRxiv - Molecular Biology 2023

  Quote: ... EMCN (sc-65495, Santa Cruz Biotechnology, USA, 1:500), YBX1 (4202S ...
• Preclinical Screening of Splice-Switching Antisense Oligonucleotides in PDAC Organoids

  Ledong Wan, et al., bioRxiv - Pharmacology and Toxicology 2023

  Quote: ... and mouse anti-Vinculin (1:1000, Santa Cruz Biotechnology) antibodies were used with IRDye 800CW secondary antibodies (LI-COR ...
• Mmp17-deficient mice exhibit heightened goblet cell effector expression in the colon and increased resistance to chronic Trichuris muris infection

  Pia M. Vornewald, et al., bioRxiv - Immunology 2023

  Quote: ... anti-MUC2 (1:200, Santa Cruz Biotechnology, sc-15334), anti-CLCA1 (1:200 ...
• Mitosis sets nuclear homeostasis of cancer cells under confinement

  Malèke Mouelhi, et al., bioRxiv - Biophysics 2023

  Quote: ... LaminA/C (Santa Cruz Biotechnology™ at 1/100), γH2Ax (Santa Cruz Biotechnology™ at 1/200) ...
• Proteogenomic characterization reveals antitumor mechanisms of intrahepatic cholangiocarcinoma

  Weibing Wang, Shifeng Xu, bioRxiv - Biochemistry 2023

  Quote: ... and anti-GAPDH (1:3000; Santa Cruz, sc-47724), and the corresponding secondary antibodies for protein detection ...
• Tropism of AAV.CPP.16 in the respiratory tract and its application for a CRISPR-based gene therapy against SARS-CoV-2

  Zhi Yang, et al., bioRxiv - Bioengineering 2023

  Quote: ... mouse anti-CC10 (1:400, sc-390313, Santa Cruz), rabbit anti-CC10 (1:200 ...
• Weak neuronal glycolysis sustains cognition and organismal fitness

  Daniel Jimenez-Blasco, et al., bioRxiv - Cell Biology 2023

  Quote: ... 1/500 anti-Cyclin B1 (sc7393; Santa Cruz Biotechnology), 1/500 anti-Rock2 (sc398519 ...
• The circulating immune cell landscape stratifies metastatic burden in breast cancer patients

  S Mangiola, et al., bioRxiv - Cancer Biology 2023

  Quote: ... TCRδ (H-41, Santa Cruz Biotech, 1:100 dilution), pan Cytokeratin (AE1/AE3+5D3 ...
• Tau alters global gene expression affecting chromatin in the early stages of Alzheimer’s disease

  G. Siano, et al., bioRxiv - Neuroscience 2023

  Quote: ... HRP-conjugated anti-mouse 1:1000 (Santa Cruz Biotechnology), and HRP-conjugated anti-rabbit 1:1000 (Santa Cruz Biotechnology) ...
• A simple and reliable method for claustrum localization across age in mice

  Tarek Shaker, et al., bioRxiv - Neuroscience 2023

  Quote: ... mouse anti-Tle4 (sc365406, Santa Cruz Biotechnology; 1:250), goat anti-PV (PVG213 ...