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4601 - 4650 of 8862 citations for 6 1 4 dioxa 8 azaspiro 4.5 decan 8 yl 3 hydroxy 2 iminopyrimidin 4 amine since 2019

• Identification of Fibronectin 1 as a candidate genetic modifier in a Col4a1 mutant mouse model of Gould syndrome

  Mao Mao, et al., bioRxiv - Genetics 2020

  Quote: ... rabbit anti-FAK (1:1000, Santa Cruz #SC-557), rabbit anti-ILK (1:1000 ...
• Programmable downsizing of CRISPR-Cas9 activity for precise and safe genome editing

  Masaki Kawamata, et al., bioRxiv - Molecular Biology 2020

  Quote: ... Rabbit polyclonal p53 (FL-393, Santa Cruz, 1:200) and rabbit monoclonal pSmad1/5/8 (D5B10 ...
• Parkinson's disease-related phosphorylation at Tyr39 rearranges α-synuclein amyloid fibril structure revealed by cryo-EM

  Kun Zhao, et al., bioRxiv - Biophysics 2020

  Quote: ... anti-P62 (Santa Cruz Biotechnology, sc-28359, 1:200) antibodies ...
• Parkinson's disease-related phosphorylation at Tyr39 rearranges α-synuclein amyloid fibril structure revealed by cryo-EM

  Kun Zhao, et al., bioRxiv - Biophysics 2020

  Quote: ... anti-Ub (Santa Cruz Biotechnology, sc-8017, 1:200), anti-P62 (Santa Cruz Biotechnology ...
• Transient receptor vanilloid 4 (TRPV4) channels are essential for alveolar epithelial cell function

  Jonas Weber, et al., bioRxiv - Cell Biology 2019

  Quote: ... anti-CC10 (mouse, Santa Cruz, E-11, 1:200) anti-chicken (goat ...
• Thiol-ene cross-linked alginate hydrogel encapsulation modulates the extracellular matrix of kidney organoids by reducing abnormal type 1a1 collagen deposition

  Thomas Geuens, et al., bioRxiv - Bioengineering 2020

  Quote: ... laminin B2 (sc-59980, Santa Cruz Biotechnology, 1:500), nidogen (sc-133175 ...
• Male sex hormones increase excitatory neuron production in developing human neocortex

  Iva Kelava, et al., bioRxiv - Developmental Biology 2020

  Quote: ... goat anti-BRN2 (Santa Cruz, sc-6029, 1:200), sheep anti-TBR2 (R&D Systems ...
• Male sex hormones increase excitatory neuron production in developing human neocortex

  Iva Kelava, et al., bioRxiv - Developmental Biology 2020

  Quote: ... mouse anti-DLX2 (Santa Cruz, sc-393879, 1:200), mouse anti-SATB2 (Abcam ...
• A novel Axin2 knock-in mouse model for visualization and lineage tracing of WNT/CTNNB1 responsive cells

  Anoeska Agatha Alida van de Moosdijk, et al., bioRxiv - Developmental Biology 2020

  Quote: ... HSP90α/β (1:1000, Santa Cruz Biotechnology, sc-13119), Flag M1 (1:2000 ...
• Clathrin adaptor AP-1 and Stratum act in parallel pathways to control Notch activation in Drosophila Sensory Organ Precursor Cells

  Karen Bellec, et al., bioRxiv - Developmental Biology 2020

  Quote: ... goat anti-Su(H) (sc15813, Santa Cruz, 1:500), mouse anti-Cut (2B10 ...
• Newfound coding potential of transcripts unveils missing members of human protein communities

  Sebastien Leblanc, et al., bioRxiv - Systems Biology 2021

  Quote: ... 1/1000 and anti-GFP (Santa Cruz, sc-9996) 1/8000 ...
• Plasticity of Neural Connections Underlying Oxytocin-mediated Parental Behaviors of Male Mice

  Kengo Inada, et al., bioRxiv - Neuroscience 2021

  Quote: ... and anti-Myc (sc-40, Santa Cruz, 1:1000). Signal-positive cells were detected by anti-chicken Alexa Fluor 488 (703-545-155 ...
• Thiol-ene cross-linked alginate hydrogel encapsulation modulates the extracellular matrix of kidney organoids by reducing abnormal type 1a1 collagen deposition

  Thomas Geuens, et al., bioRxiv - Bioengineering 2020

  Quote: ... and SOX2 (sc-365823, Santa Cruz Biotechnology, 1:100). An Alexa Fluor 488 (Thermo Fisher Scientific ...
• Drosophila p38 MAPK Interacts with BAG-3/starvin to Regulate Age-dependent Protein Homeostasis

  Sarah M. Ryan, et al., bioRxiv - Genetics 2020

  Quote: ... goat anti total p38 1:1000 (Santa Cruz Biotechnology), rabbit anti-stv 1:10,000 (gift of Jrög Höhfeld ...
• Hox-dependent coordination of cardiac progenitor cell patterning and differentiation

  Sonia Stefanovic, et al., bioRxiv - Developmental Biology 2020

  Quote: ... goat anti-Tbx5 (Santa Cruz sc-7866, 1/250).
• Rab40/Cullin5 complex regulates EPLIN and actin cytoskeleton dynamics during cell migration and invasion

  Erik S Linklater, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-α-tubulin – (WB 1:2500, Santa Cruz 23948), pFAK Y397 (WB 1:1000 ...
• Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV

  Alexey Stukalov, et al., bioRxiv - Systems Biology 2021

  Quote: ... ACTB-HRP (Santa Cruz; sc-47778; 1:5000 dilution), MAP1LC3B (Cell Signaling ...
• A conserved ubiquitin- and ESCRT-dependent pathway to regulate human lysosomal membrane proteins

  Weichao Zhang, et al., bioRxiv - Cell Biology 2020

  Quote: ... mouse anti-ALIX (1:500, 1A12, Santa Cruz Biotechnology), mouse anti-Vps22 (1:500 ...
• RAI1 Regulates Activity-Dependent Nascent Transcription and Synaptic Scaling

  Patricia M. Garay, et al., bioRxiv - Neuroscience 2019

  Quote: ... Anti-PCNA antibody (Santa Cruz sc-56, 1:1000) was used for a loading control ...
• The master energy homeostasis regulator PGC-1α couples transcriptional co-activation and mRNA nuclear export

  Simeon R. Mihaylov, et al., bioRxiv - Molecular Biology 2021

  Quote: ... TFAM (C-9) [1:1000] (Santa Cruz sc-376672), c-myc [1:1000] (Thermo Fisher MA1-980) ...
• Klebsiella pneumoniae hijacks the Toll-IL-1R protein SARM1 in a type I IFN-dependent manner to antagonize host immunity

  Claudia Feriotti, et al., bioRxiv - Microbiology 2021

  Quote: ... anti-HA (1:1000, Santa Cruz Biotechnology sc-805). Immunoreactive bands were visualized by incubation with HRP-conjugated IgG Secondary antibody (anti-goat ...
• Phosphorylation of pericyte FAK-Y861 affects tumour cell apoptosis and tumour blood vessel regression

  Delphine M. Lees, et al., bioRxiv - Cancer Biology 2020

  Quote: ... and endomucin (clone V.7C7, Santa Cruz; 1:100) antibodies ...
• Differential processing and localization of human Nocturnin controls metabolism of mRNA and nicotinamide dinucleotide metabolites

  Elizabeth T. Abshire, et al., bioRxiv - Molecular Biology 2020

  Quote: ... Mouse anti-uL1 (1:1000 Santa Cruz, sc-100827). Secondary antibodies used were mouse anti-goat IgG–HRP (1:5000 ...
• A high throughput screening assay for inhibitors of SARS-CoV-2 pseudotyped particle entry

  Miao Xu, et al., bioRxiv - Pharmacology and Toxicology 2021

  Quote: ... 1:1000 primary mouse-anti-luciferase antibody (Santa Cruz) was added ...
• Primary cilium-dependent cAMP/PKA signaling at the centrosome regulates neuronal migration

  Julie Stoufflet, et al., bioRxiv - Neuroscience 2019

  Quote: ... AC3 (Santa Cruz, C-20 sc-588, 1/200), Arl13b (UC Davis/NIH NeuroMab Facility ...
• Conjugated activation of myocardial-specific transcription of Gja5 by a pair of Nkx2-5-Shox2 co-responsive elements

  Tianfang Yang, et al., bioRxiv - Developmental Biology 2020

  Quote: ... anti-GFP (sc-9996, Santa Cruz Biotechnology; 1:200), anti-β-galactosidase (ab9361 ...
• Distribution and localization of phosphatidylinositol 5-phosphate, 4-kinase alpha and beta in the brain

  Evan K. Noch, et al., bioRxiv - Neuroscience 2020

  Quote: ... were used: PI5P4Kα (1:500, Santa Cruz sc-100406), PI5P4Kα (1:500 ...
• Loss of function of the mitochondrial peptidase PITRM1 induces proteotoxic stress and Alzheimer’s disease-like pathology in human cerebral organoids

  Dina Ivanyuk, et al., bioRxiv - Neuroscience 2020

  Quote: ... mouse anti-APP (1:500, Santa Cruz Biotechnology sc53822), mouse anti-Ubiquitin (1:100 ...
• Genetic ablation of SOD1^G37R selectively from corticofugal projection neurons protects corticospinal neurons from degeneration without affecting ALS onset and progression

  Jelena Scekic-Zahirovic, et al., bioRxiv - Neuroscience 2020

  Quote: ... rabbit anti-TLE4 (Santa Cruz sc-9125, 1/100), mouse anti-SATB2 (Abcam ab21502 ...
• Presynaptic inhibition of cutaneous afferents prevents self-generated itch

  Augusto Escalante, Rüdiger Klein, bioRxiv - Neuroscience 2020

  Quote: ... rabbit anti-cFos (1:2000) (sc-52, Santa Cruz), rabbit monoclonal anti-cFos (1:2000 ...
• Long-term synaptic depression triggers local biogenesis of autophagic vesicles in dendrites and requires autophagic degradation

  Emmanouela Kallergi, et al., bioRxiv - Neuroscience 2020

  Quote: ... Atg16L1 E-10 (1:1000, Santa Cruz, sc-393274), GRP78Bip (1:1000 ...
• Dynamic rewiring of the human interactome by interferon signalling

  Craig H. Kerr, et al., bioRxiv - Systems Biology 2019

  Quote: ... mouse anti-IFIT2 (1:1000; Santa Cruz - sc-390724), mouse anti-IFI35 (1:1000 ...
• Dynamic rewiring of the human interactome by interferon signalling

  Craig H. Kerr, et al., bioRxiv - Systems Biology 2019

  Quote: ... mouse anti-IFI35 (1:1000; Santa Cruz - sc-100769), or rabbit anti-NMI (1:1000 ...
• Single Cell RNAseq Reveals A Critical Role of Chloride Channels in Airway Development

  Mu He, et al., bioRxiv - Developmental Biology 2019

  Quote: ... SCGB1A1/CC10 (1:200, B6, Santa Cruz, sc-390313), rabbit anti-KRT13 (1:500 ...
• LonP1 Orchestrates UPRmt and UPRER and Mitochondrial Dynamics to Regulate Heart Function

  Bin Lu, et al., bioRxiv - Cell Biology 2019

  Quote: ... anti-Tid-1 L/S (sc-18820, Santa Cruz); anti-OMA1 (sc-515788 ...
• XAB2 prevents abortive recombinational repair of replication-associated DNA double-strand breaks and its loss is synthetic lethal with RAD52 inhibition

  Abhishek B. Sharma, et al., bioRxiv - Molecular Biology 2020

  Quote: ... HRP mouse (Santa Cruz, sc-516102, dilution 1:10,000).
• MiR-9-5p protects from kidney fibrosis by metabolic reprogramming

  Marta Fierro-Fernández, et al., bioRxiv - Molecular Biology 2019

  Quote: ... α-Actin (1A4) (1:500, sc-32251, Santa Cruz Biotechnology) and F4/80 (1:100 ...
• Rapid fabrication of collagen bundles mimicking tumor-associated collagen signatures

  Xiangyu Gong, Jonathan Kulwatno, K. L. Mills, bioRxiv - Bioengineering 2019

  Quote: Primary antibodies for vimentin (1:5000; Santa Cruz Biotechnology), E-cadherin (1:2000 ...
• Human Retina-on-a-Chip: Merging Organoid and Organ-on-a-Chip Technology to Generate Complex Multi-Layer Tissue Models

  Kevin Achberger, et al., bioRxiv - Bioengineering 2019

  Quote: AP2α (1:100, sc-12726, Santa Cruz Biotechnology, USA)
• Human Retina-on-a-Chip: Merging Organoid and Organ-on-a-Chip Technology to Generate Complex Multi-Layer Tissue Models

  Kevin Achberger, et al., bioRxiv - Bioengineering 2019

  Quote: BRN3B (1:50, sc-31989, Santa Cruz Biotechnology, USA)
• Human Retina-on-a-Chip: Merging Organoid and Organ-on-a-Chip Technology to Generate Complex Multi-Layer Tissue Models

  Kevin Achberger, et al., bioRxiv - Bioengineering 2019

  Quote: CHX10 (1:200, sc-21690, Santa Cruz Biotechnology, USA)
• Human Retina-on-a-Chip: Merging Organoid and Organ-on-a-Chip Technology to Generate Complex Multi-Layer Tissue Models

  Kevin Achberger, et al., bioRxiv - Bioengineering 2019

  Quote: PKCα (1:500, sc-208, Santa Cruz Biotechnology, USA)
• Human Retina-on-a-Chip: Merging Organoid and Organ-on-a-Chip Technology to Generate Complex Multi-Layer Tissue Models

  Kevin Achberger, et al., bioRxiv - Bioengineering 2019

  Quote: Rhodopsin (1:200, sc-57432, Santa Cruz Biotechnology, USA)
• Protein features for assembly of the RNA editing helicase 2 subcomplex (REH2C) in Trypanosome holo-editosomes

  Vikas Kumar, et al., bioRxiv - Molecular Biology 2019

  Quote: ... EF-1 α1 antibody (sc-21758; Santa Cruz Biot) diluted to 1:200 (v/v ...
• Septin 2/6/7 complexes tune microtubule plus end growth and EB1 binding in a concentration- and filament-dependent manner

  Konstantinos Nakos, et al., bioRxiv - Cell Biology 2019

  Quote: ... rabbit antibody against GST-tag (1:10,000; Santa Cruz) or rabbit antibody against SEPT7 (1:10,000 ...
• Functional Exploration of Copy Number Alterations in a Drosophila Model of Triple Negative Breast Cancer

  Jennifer E. L. Diaz, et al., bioRxiv - Genetics 2020

  Quote: ... or Myc (Santa Cruz Myc d1-717, 1:200) overnight at 4°C ...
• p57Kip2 regulates embryonic haematopoietic stem cell numbers by controlling the size of the sympathoadrenal progenitor pool

  Chrysa Kapeni, et al., bioRxiv - Developmental Biology 2021

  Quote: ... Ngfr (goat C-20, 1:300, Santa Cruz Biotechnology) and Sox10 (goat N-20 ...
• Ubiquitin-protein ligase Ubr5 cooperates with Hedgehog signalling to promote skeletal tissue homeostasis

  David Mellis, et al., bioRxiv - Genetics 2020

  Quote: ... goat anti-PTCH1 (1:50, Santa Cruz, Dallas, US); rabbit anti-GLI1 (1:50 ...
• DYNLL1 mis-splicing is associated with replicative genome instability in SF3B1 mutant cells

  Annie S. Tam, et al., bioRxiv - Cell Biology 2021

  Quote: ... p-ATM (1:500, Santa Cruz cat#sc-47739), p-CHK2 (Th468 ...
• Loss of C9orf72 perturbs the Ran-GTPase gradient and generates compositionally diverse cytoplasmic Importin β-1 granules in motor and cortical neurons in vivo

  Philip McGoldrick, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-RanGAP (Santa Cruz sc-25630, 1:250), mouse anti-Ran-GTPase (BD Biosciences 610340 ...