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2351 - 2400 of 8510 citations for 6 Chloro 2 3 diphenylimidazo 1 2 b pyridazine since 2019

• Discovery of ciliary G protein-coupled receptors regulating pancreatic islet insulin and glucagon secretion

  Chien-Ting Wu, et al., bioRxiv - Physiology 2020

  Quote: ... FFAR4 (Santa Cruz, sc-390752, 1:100), Acetylated tubulin (Sigma ...
• Tousled-like kinase activity is required for transcriptional silencing and suppression of innate immune signaling

  Sandra Segura-Bayona, et al., bioRxiv - Molecular Biology 2019

  Quote: ... CtIP (Santa Cruz sc-271339, 1:500); BLM (Abcam ab2179 ...
• Tousled-like kinase activity is required for transcriptional silencing and suppression of innate immune signaling

  Sandra Segura-Bayona, et al., bioRxiv - Molecular Biology 2019

  Quote: ... MRE11 (Santa Cruz sc-135992, 1:200); CtIP (Santa Cruz sc-271339 ...
• Mitotic spindle assembly is controlled by the APC/C localized at the centrosome

  Thomas Tischer, Jing Yang, David Barford, bioRxiv - Cell Biology 2020

  Quote: ... Cdc20 (Santa Cruz sc-8358, 1:100), Bub3 (BD 811730 ...
• Discovery and 3D imaging of a novel ΔNp63-expressing basal cell type in human pancreatic ducts with implications in disease

  Sandrina Martens, et al., bioRxiv - Pathology 2020

  Quote: ... HNF1β (1/100, sc-7411, Santa Cruz), PDX1 (1/100 ...
• Intraflagellar transport complex B proteins regulate the Hippo effector Yap1 during cardiogenesis

  Marina Peralta, et al., bioRxiv - Developmental Biology 2019

  Quote: ... Yap1 (Santa Cruz sc-101199, 1:100), Amotl1 (Sigma HPA001196 ...
• Intraflagellar transport complex B proteins regulate the Hippo effector Yap1 during cardiogenesis

  Marina Peralta, et al., bioRxiv - Developmental Biology 2019

  Quote: ... Wt1 (Santa Cruz sc-192, 1:50), Yap1 (Santa Cruz sc-101199 ...
• Noncanonical scaffolding of G_αi and β-arrestin by G protein-coupled receptors

  Jeffrey S. Smith, et al., bioRxiv - Cell Biology 2019

  Quote: ... Galpha i-1 (13533, Santa Cruz Biotechnology), Galpha q/11/14 (365906 ...
• CircHIPK3 dysregulation of the miR-30c/DLL4 axis is essential for KSHV lytic replication

  Katherine L. Harper, et al., bioRxiv - Microbiology 2021

  Quote: ... ORF57 (Santa Cruz sc-135747 1/1000), GAPDH (Proteintech 60004-1-Ig 1/5000) ...
• miR-183/96/182 cluster is an important morphogenetic factor targeting PAX6 expression in differentiating human retinal organoids

  Lucie Peskova, et al., bioRxiv - Molecular Biology 2020

  Quote: ... SOX2 (sc-365823, Santa Cruz, 1:1000), SOX1 (bs-12276R ...
• Phosphorylation of pericyte FAK-Y861 affects tumour cell apoptosis and tumour blood vessel regression

  Delphine M. Lees, et al., bioRxiv - Cancer Biology 2020

  Quote: ... endomucin (V7.C7, Santa Cruz, 1:1000). The anti-HSC70 (Santa Cruz ...
• Makorin 1 controls embryonic patterning by alleviating Bruno1-mediated repression of oskar translation

  Annabelle Dold, et al., bioRxiv - Developmental Biology 2019

  Quote: ... mouse α-ubiquitin (1:1000; Santa Cruz) Fab α-pAbp (2.5 µg in 5 ml) ...
• Fragile X Mental Retardation Protein regulates R-loop formation and prevents global chromosome fragility

  Arijita Chakraborty, et al., bioRxiv - Genomics 2019

  Quote: ... anti-UGT1A (Santa Cruz Biotechnology, 1:250), anti-CYP2C9 (Invitrogen ...
• Fate of developmental mechanisms of myocardial plasticity in the postnatal heart

  Konstantinos E. Hatzistergos, et al., bioRxiv - Developmental Biology 2019

  Quote: ... Nkx2.5 (1:50, Santa Cruz Biotechnologies, #SC8697), cardiac troponin-T (1:200 ...
• PRSS2 stimulates tumor growth by remodeling the TME via repression of Tsp1

  Lufei Sui, et al., bioRxiv - Cancer Biology 2021

  Quote: ... p53 (DO-1 mouse mAb, Santa Cruz), LRP1 (rabbit pAb ...
• Human Induced Pluripotent Stem Cell Derived Sensory Neurons are Sensitive to the Neurotoxic Effects of Paclitaxel

  Chenling Xiong, et al., bioRxiv - Pharmacology and Toxicology 2020

  Quote: ... goat anti-Peripherin (1:500, Santa Cruz), pig anti-TRPV1 (1:200 ...
• Human Induced Pluripotent Stem Cell Derived Sensory Neurons are Sensitive to the Neurotoxic Effects of Paclitaxel

  Chenling Xiong, et al., bioRxiv - Pharmacology and Toxicology 2020

  Quote: ... goat anti-SOX10 (1:500, Santa Cruz), mouse anti-BRN3A (1:500 ...
• Serine 165 Phosphorylation of SHARPIN regulates the Activation of NF-κB

  An Thys, et al., bioRxiv - Immunology 2020

  Quote: ... HOIL-1 ((sc-393754, Santa Cruz Biotechnology) and linear ubiquitin ...
• Senolytic activity of small molecular polyphenols from olive restores chondrocyte redifferentiation and cartilage regeneration in osteoarthritis

  Marta Varela-Eirín, et al., bioRxiv - Cell Biology 2019

  Quote: ... Twist-1 (Santa Cruz Biotechnology, sc-81417), CD166 (Santa Cruz Biotechnology ...
• DRP1-mediated regulation of mitochondrial dynamics determines the apoptotic response upon embryonic differentiation

  Barbara Pernaute, et al., bioRxiv - Developmental Biology 2019

  Quote: ... anti-Bad (Santa Cruz Biotechnology, 1/500), anti-Bax N20 (Santa Cruz Biotechnology ...
• DRP1-mediated regulation of mitochondrial dynamics determines the apoptotic response upon embryonic differentiation

  Barbara Pernaute, et al., bioRxiv - Developmental Biology 2019

  Quote: ... anti-Tom20 (Santa Cruz Biotechnologies, 1/1000), anti-Drp1 (Cell Signalling ...
• RIPK3 upregulation confers robust proliferation and collateral cystine-dependence on breast cancer recurrence

  Chao-Chieh Lin, et al., bioRxiv - Cancer Biology 2019

  Quote: ... RIPK3 (1:1000, sc-374639, Santa Cruz); GAPDH (1:2000 ...
• RIPK3 upregulation confers robust proliferation and collateral cystine-dependence on breast cancer recurrence

  Chao-Chieh Lin, et al., bioRxiv - Cancer Biology 2019

  Quote: ... GAPDH (1:2000, sc-25778, Santa Cruz); Phospho-MLKL (Ser345 ...
• Isolation and long-term expansion of a single adult human renal epithelial cell with efficient kidney regeneration capacity

  Yujia Wang, et al., bioRxiv - Cell Biology 2020

  Quote: ... Krt7 (1:500, sc-53263, Santa Cruz), PAX2 (1:50 ...
• Topoisomerase II inhibitors induce cGAS-STING dependent inflammation resulting in cytokine induction and immune checkpoint activation

  R. D. A Wilkinson, et al., bioRxiv - Cancer Biology 2019

  Quote: ... anti-dsDNA (1/50; Santa Cruz Biotechnology), anti-γH2AX (1/2000 ...
• Aicardi-Goutières Syndrome gene Rnaseh2c is a metastasis susceptibility gene in breast cancer

  Sarah K Deasy, et al., bioRxiv - Cancer Biology 2019

  Quote: ... goat anti-rabbit (1:10,000; Santa Cruz), anti-rabbit (1:3000 ...
• Pre-marked chromatin and transcription factor co-binding shape the pioneering activity of Foxa2

  Filippo M. Cernilogar, et al., bioRxiv - Genomics 2019

  Quote: ... α-T 1:300 (Santa Cruz #17743), α-Cer1 1:500 (R&D #AF1075 ...
• NG2 glia are required for maintaining microglia homeostatic state

  Yingjun Liu, Adriano Aguzzi, bioRxiv - Neuroscience 2019

  Quote: ... PDGFRα (1:500, Santa Cruz, SC-338) and Iba1 (1:1000 ...
• High-phytate/low-calcium diet is a risk factor for crystal nephropathies, renal phosphate wasting, and bone loss

  Ok-Hee Kim, et al., bioRxiv - Physiology 2019

  Quote: ... CYP24A1 (S-20, 1:200; Santa Cruz), and VDR (C-20 ...
• Depletion of limiting rDNA structural complexes triggers chromosomal instability and replicative aging of Saccharomyces cerevisiae

  Ryan Fine, et al., bioRxiv - Genetics 2019

  Quote: ... 1:1000 α-Sir4 (Santa Cruz Biotechnology); 1:1000 α-Sir3 (Santa Cruz Biotechnology) ...
• Depletion of limiting rDNA structural complexes triggers chromosomal instability and replicative aging of Saccharomyces cerevisiae

  Ryan Fine, et al., bioRxiv - Genetics 2019

  Quote: ... 1:1000 α-Sir3 (Santa Cruz Biotechnology). HRP-conjugated secondary antibodies (Promega ...
• Evidence of SARS-CoV2 entry protein ACE2 in the human nose and olfactory bulb

  M. Klingenstein, et al., bioRxiv - Cell Biology 2020

  Quote: ... TMPRSS2 ms (Santa Cruz, Sc515727, 1:50), TUBB3 ms (BioLegend ...
• Ubiquitin-protein ligase Ubr5 cooperates with Hedgehog signalling to promote skeletal tissue homeostasis

  David Mellis, et al., bioRxiv - Genetics 2020

  Quote: ... rabbit anti-SOX9 (1:50 Santa Cruz); rabbit anti-RUNX2 (1:250 ...
• DYNLL1 mis-splicing is associated with replicative genome instability in SF3B1 mutant cells

  Annie S. Tam, et al., bioRxiv - Cell Biology 2021

  Quote: ... CDC7 (1:500, Santa Cruz, sc-56274), p-MCM2 (1:2000 ...
• DYNLL1 mis-splicing is associated with replicative genome instability in SF3B1 mutant cells

  Annie S. Tam, et al., bioRxiv - Cell Biology 2021

  Quote: ... RAD51 (1:500, Santa Cruz sc-398587), CDC7 (1:500 ...
• 3D models of Alzheimer’s disease patient microglia recapitulate disease phenotype and show differential drug responses compared to 2D

  Carla Cuní-López, et al., bioRxiv - Neuroscience 2021

  Quote: ... GalC (1:50; Santa Cruz, #sc-518055), Doublecortin (DCX ...
• Impaired renal gluconeogenesis is a major determinant of acute kidney injury associated mortality

  David Legouis, et al., bioRxiv - Cell Biology 2019

  Quote: ... AQP2 (Santa Cruz sc-515770 1:500). All sections were stained with Hoechst 33342 (Life Technologies ...
• Extracellular vesicles from retinal pigment epithelial cells expressing R345W-Fibulin-3 induce epithelial-mesenchymal transition in recipient cells

  Mi Zhou, et al., bioRxiv - Cell Biology 2020

  Quote: ... 1:1,000 (sc-03, Santa Cruz Biotechnology), rabbit anti-ALG-2-interacting protein X (Alix ...
• Enhanced RhoA signaling stabilizes E-cadherin in migrating epithelial monolayers

  Shafali Gupta, et al., bioRxiv - Cell Biology 2021

  Quote: ... Anillin (Santa Cruz SC-271814; 1:100), Myosin IIB (Abcam ab684 ...
• The Ca²⁺-activated cation channel TRPM4 is a positive regulator of pressure overload-induced cardiac hypertrophy

  Yang Guo, et al., bioRxiv - Physiology 2020

  Quote: ... anti-GATA4 (1:1000; Santa Cruz Biotechnology). Anti-Glyceraldehyde-3-phosphate dehydrogenase (GAPDH ...
• The Ca²⁺-activated cation channel TRPM4 is a positive regulator of pressure overload-induced cardiac hypertrophy

  Yang Guo, et al., bioRxiv - Physiology 2020

  Quote: ... anti-CaMKIIδ (1:1000; Santa Cruz Biotechnology), anti-total HDAC4 (1:1500 ...
• Identification and Characterization of Fbxl22, a novel skeletal muscle atrophy-promoting E3 ubiquitin ligase

  David C. Hughes, et al., bioRxiv - Physiology 2020

  Quote: ... Vimentin (1:1000, Santa Cruz, sc-373717).
• Identification and Characterization of Fbxl22, a novel skeletal muscle atrophy-promoting E3 ubiquitin ligase

  David C. Hughes, et al., bioRxiv - Physiology 2020

  Quote: ... Dystrophin (1:1000, Santa Cruz, sc-365954), α-actinin (1:1000 ...
• K29-Linked Ubiquitin Signaling Regulates Proteotoxic Stress Response and Cell Cycle

  Yuanyuan Yu, et al., bioRxiv - Cell Biology 2021

  Quote: ... Anti β-Actin (Santa Cruz, 1:1000), Anti GAPDH (Santa Cruz ...
• The cell adhesion molecule Sdk1 shapes assembly of a retinal circuit that detects localized edges

  Pierre-Luc Rochon, et al., bioRxiv - Neuroscience 2021

  Quote: ... mouse anti-Brn3c (1:250, Santa Cruz Biotechnology ...
• Deletion of INPP5E in the murine retina impairs axoneme formation and prevents photoreceptor disc morphogenesis

  Ali S. Sharif, et al., bioRxiv - Neuroscience 2020

  Quote: ... G8 (1:500, anti-GRK1, Santa Cruz). PRPH2 (2B6 ...
• The Endothelin Receptor Antagonist Macitentan Ameliorates Endothelin-Mediated Vasoconstriction and Promotes Neuroprotection of Retinal Ganglion Cells in Rats

  Dorota L. Stankowska, et al., bioRxiv - Neuroscience 2020

  Quote: ... goat anti-Brn3a (1:200; Santa Cruz) for 72 hours at 4°C ...
• Sister chromatid exchanges induced by perturbed replication are formed independently of homologous recombination factors

  Anne Margriet Heijink, et al., bioRxiv - Cancer Biology 2021

  Quote: ... RAD52 (Santa Cruz, sc-365341, 1:250), SLX4 (BTBD12 ...
• Aberrant FGF signaling promotes granule neuron precursor expansion in SHH subgroup infantile medulloblastoma

  Odessa R. Yabut, et al., bioRxiv - Cancer Biology 2021

  Quote: ... rabbit anti-Gli3 (1:100; Santa Cruz), rabbit anti-Pax6 (1:1000 dilution ...
• Cdk5 drives formation of heterogeneous pancreatic neuroendocrine tumors

  Angela M. Carter, et al., bioRxiv - Cancer Biology 2021

  Quote: ... RBL1 (Santa Cruz sc-318; 1:500), pS392-SUV39H1 (Bibb Lab ...