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2201 - 2250 of 8510 citations for 6 Chloro 2 3 diphenylimidazo 1 2 b pyridazine since 2019

• Combinatorial small molecule-mediated activation of CBP/p300 with environmental enrichment in chronic severe experimental spinal cord injury to enable axon regeneration and sprouting for functional recovery

  Franziska Mueller, et al., bioRxiv - Neuroscience 2021

  Quote: ... ATF3 (1:100, Santa Cruz, sc-188), pErk (1:250 ...
• The RNA helicases DDX5 and DDX17 facilitate neural differentiation of human pluripotent stem cells NTERA2

  Praewa Suthapot, et al., bioRxiv - Neuroscience 2021

  Quote: ... and TUBB3 (Santa Cruz, 1:150 dilution). Cells were analyzed with a fluorescence microscope (Olympus ...
• Alterations in leptin signaling in Amyotrophic Lateral Sclerosis (ALS)

  Agueda Ferrer-Donato, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-Akt (1:1000 Santa Cruz); mouse anti-STAT3 (1:1000 ...
• Cerebral organoid model reveals excessive proliferation of human caudal late interneuron progenitors in Tuberous Sclerosis Complex

  Oliver L. Eichmüller, et al., bioRxiv - Neuroscience 2020

  Quote: ... and 1 mM db-cAMP (Santa Cruz). Gradual transfer from HN+A to LN was performed as follows with feedings performed every third day ...
• COUP-TFI regulates diameter of the axon initial segment in the mammalian neocortex

  Xuanyuan Wu, et al., bioRxiv - Neuroscience 2020

  Quote: ... Mouse anti-AnkG (1:500, Santa Cruz), Chicken anti-GFP (1:1000 ...
• Acetyltransferases GCN5 and PCAF are required for B lymphocyte maturation in mice

  Valentyn Oksenych, Dan Su, Jeremy A. Daniel, bioRxiv - Immunology 2021

  Quote: ... clone A-11 (1:500, Santa Cruz Biotechnol-ogy ...
• Combining Plasma Extracellular Vesicle Let-7b-5p, miR-184 and Circulating miR-22-3p Levels for NSCLC Diagnosis and for Predicting Drug Resistance

  G. P. Vadla, et al., bioRxiv - Cancer Biology 2021

  Quote: ... and flotillin (1:1000, Santa Cruz #74566). Secondary antibodies were anti-mouse horseradish peroxidase (1:10000 ...
• Hepatocyte Cell Cycle Progression Depends on a Transcriptional Repressor Cascade Downstream of Wnt Signaling

  Yinhua Jin, et al., bioRxiv - Cell Biology 2021

  Quote: ... Hnf4a (rabbit 1:50; Santa Cruz sc8987). Samples were imaged at 20X magnification using a Zeiss Imager Z.2 and processed and analyzed with the ImageJ software.
• Lin28a rejuvenates muscle stem cells via mitochondrial optimization

  Peng Wang, et al., bioRxiv - Cell Biology 2021

  Quote: ... P53 (sc-126; Santa Cruz; 1:100), IMP1/2/3 (sc-271785 ...
• Lin28a rejuvenates muscle stem cells via mitochondrial optimization

  Peng Wang, et al., bioRxiv - Cell Biology 2021

  Quote: ... α-actinin (sc-7453; Santa Cruz; 1:500), 8-oxo-guanine (ab206461 ...
• Phylogenetic profiling and cellular analyses of ARL16 reveal roles in traffic of IFT140 and INPP5E

  Skylar I. Dewees, et al., bioRxiv - Cell Biology 2021

  Quote: ... CEP164 (1:100; Santa Cruz; sc-515403), rootletin (1:1000 ...
• The ARF GAPs ELMOD1 and ELMOD3 act at the Golgi and Cilia to Regulate Ciliogenesis and Ciliary Protein Traffic

  Rachel E. Turn, et al., bioRxiv - Cell Biology 2021

  Quote: ... CEP164 (1:100; Santa Cruz; sc-515403), CP110 (1:100 ...
• KDM6A mediated expression of the long noncoding RNA DINO causes TP53 tumor suppressor stabilization in Human Papillomavirus type 16 E7 expressing cells

  Surendra Sharma, Karl Munger, bioRxiv - Cancer Biology 2020

  Quote: ... E2F1 (sc-251, Santa Cruz, 1:500), KDM6A (ab36938 ...
• Membrane metalloendopeptidase suppresses prostate carcinogenesis by attenuating effects of gastrin-releasing peptide on stem/progenitor cells

  Chieh-Yang Cheng, et al., bioRxiv - Cancer Biology 2019

  Quote: ... NT (Santa Cruz, #sc-20806, 1:1000), and VIP (Abcam ...
• Membrane metalloendopeptidase suppresses prostate carcinogenesis by attenuating effects of gastrin-releasing peptide on stem/progenitor cells

  Chieh-Yang Cheng, et al., bioRxiv - Cancer Biology 2019

  Quote: ... GRP (Santa Cruz, #sc-7788, 1:100), NT (Santa Cruz ...
• Membrane metalloendopeptidase suppresses prostate carcinogenesis by attenuating effects of gastrin-releasing peptide on stem/progenitor cells

  Chieh-Yang Cheng, et al., bioRxiv - Cancer Biology 2019

  Quote: ... p63 (Santa Cruz, #sc-8431, 1:1000), PTEN (Cell Signaling Technology ...
• Sporadic activation of an oxidative stress-dependent NRF2–p53 signaling network in breast epithelial spheroids and premalignancies

  Elizabeth J. Pereira, et al., bioRxiv - Cancer Biology 2019

  Quote: ... p53 (Santa Cruz #sc-126, 1:200). Slides were incubated the next day for 1 hr in the following secondary antibodies ...
• The IRE1/XBP1 signaling axis promotes skeletal muscle regeneration through a cell non-autonomous mechanism

  Anirban Roy, et al., bioRxiv - Cell Biology 2021

  Quote: ... or anti-MyoD (1:200, Santa Cruz Biotechnology Cat# sc-377460 RRID:AB_631992 ...
• Mitochondrial Proteome of Affected Neurons in a Mouse Model of Leigh Syndrome

  Alejandro Gella, et al., bioRxiv - Neuroscience 2019

  Quote: ... TOM20 (1:5,000, #sc11415 Santa Cruz Biotech), β-actin (1:40,000 ...
• Bromelain Inhibits SARS-CoV-2 Infection in VeroE6 Cells

  Satish Sagar, et al., bioRxiv - Microbiology 2020

  Quote: ... 1:1000 (Santa Cruz Biotechnology, TX, USA); anti-SARS Spike protein 0.05 μg/ml ...
• Nuclear dengue virus NS5 antagonizes expression of PAF1-dependent immune response genes

  Marine J. Petit, et al., bioRxiv - Microbiology 2021

  Quote: ... or STAT2 (1:200, Santa Cruz Biotechnology) (S1 Fig) ...
• Amyloid plaque deposition accelerates tau propagation via activation of microglia in a humanized APP mouse model

  Kevin A. Clayton, et al., bioRxiv - Neuroscience 2020

  Quote: ... Tsg101 1:300 (Santa Cruz #sc-7964), DAPI 1:2500 (Thermo #62248) ...
• High resolution mouse subventricular zone stem cell niche transcriptome reveals features of lineage, anatomy, and aging

  Xuanhua P. Xie, et al., bioRxiv - Neuroscience 2020

  Quote: ... goat anti-Sox2 (Santa Cruz, 1:200), rabbit anti-Mki67 (Novus ...
• LORE homomerization is required for 3-OH-C10:0 induced immune signaling

  Sabine Eschrig, et al., bioRxiv - Plant Biology 2021

  Quote: ... 1:500 c-Myc 9E10 (Santa Cruz) with 1:5000 anti-mouse sc-2031 (Santa Cruz) ...
• IPSC-derived midbrain astrocytes from Parkinson’s disease patients carrying pathogenic SNCA mutations exhibit alpha-synuclein aggregation, mitochondrial fragmentation and excess calcium release

  Peter A. Barbuti, et al., bioRxiv - Neuroscience 2020

  Quote: ... -FoxA2 (1:100; Santa Cruz, sc-101060), -GI Syn (1:100 ...
• Scaling concepts in ’omics: nuclear lamin-B scales with tumor growth and predicts poor prognosis, whereas fibrosis can be pro-survival

  Manasvita Vashisth, et al., bioRxiv - Cancer Biology 2021

  Quote: ... LMNB (1:500, Santa Cruz, #sc-6217). Samples were washed three times in 0.1% BSA in PBS and incubated with the corresponding secondary antibodies at 1:500 dilution for 1.5 hrs at RT (Alexa Fluor 488 and 647 nm ...
• Alterations in leptin signaling in Amyotrophic Lateral Sclerosis (ALS)

  Agueda Ferrer-Donato, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-STAT3 (1:500; Santa Cruz), and rabbit anti-STAT3 (Tyr705 ...
• EWSR1 affects PRDM9-dependent histone 3 methylation and provides a link between recombination hotspots and the chromosome axis

  Hui Tian, et al., bioRxiv - Developmental Biology 2020

  Quote: ... DMC1 (1:200, Santa Cruz, sc-8973) or MLH1 (1:100 ...
• EWSR1 affects PRDM9-dependent histone 3 methylation and provides a link between recombination hotspots and the chromosome axis

  Hui Tian, et al., bioRxiv - Developmental Biology 2020

  Quote: ... BRCA1 (1:200, Santa Cruz, sc-642), ATR (1:500 ...
• EWSR1 affects PRDM9-dependent histone 3 methylation and provides a link between recombination hotspots and the chromosome axis

  Hui Tian, et al., bioRxiv - Developmental Biology 2020

  Quote: ... ATR (1:500, Santa Cruz, sc-1887), HORMAD1 (1:500 ...
• Loss of the Er81 Transcription Factor in Cholinergic Cells Alters Striatal Activity and Habit Formation

  Yadollah Ranjbar-Slamloo, et al., bioRxiv - Neuroscience 2020

  Quote: ... mouse anti-Lhx6 (1:X; Santa Cruz), rabbit anti-mgluR5 (1:50 ...
• Joint degeneration in a mouse model of pseudoachondroplasia: ER stress, inflammation and autophagy blockage

  Jacqueline T. Hecht, et al., bioRxiv - Pathology 2021

  Quote: ... PDI (Santa Cruz; SC-20132, 1:100), p16 INK4a - (Abcam ...
• Joint degeneration in a mouse model of pseudoachondroplasia: ER stress, inflammation and autophagy blockage

  Jacqueline T. Hecht, et al., bioRxiv - Pathology 2021

  Quote: ... CHOP (Santa Cruz; SC-575; 1:100), interleukin 1 (IL-1 ...
• Salmonella Enteritidis Effector AvrA suppresses autophagy by reducing Beclin-1 protein

  Yang Jiao, et al., bioRxiv - Microbiology 2020

  Quote: ... anti-lysozyme (1:100, sc27958, Santa Cruz Biotechnology ...
• Generating new FANCA-deficient HNSCC cell lines by genomic editing recapitulate the cellular phenotypes of Fanconi anemia

  Ricardo Errazquin, et al., bioRxiv - Cancer Biology 2020

  Quote: ... anti-FANCD2 (1:200, Santa Cruz Biotechnology), anti-vinculin (Abcam ...
• The Endoplasmic Reticulum pool of Bcl-xL dampens the Unfolded Protein Response through IP3R-dependent Calcium Release

  Lea Jabbour, et al., bioRxiv - Cell Biology 2021

  Quote: ... α-Tubulin (Santa Cruz #sc-32293; 1/1000), Actin (Sigma-Aldrich #A2066 ...
• Fructose 1,6-bisphosphate sensing by pyruvate kinase isozymes M2 (PKM2) controls MyoD stability and myogenic differentiation

  Minchul Kim, Yao Zhang, Carmen Birchmeier, bioRxiv - Cell Biology 2020

  Quote: ... MyoG (Santa Cruz sc-12732, 1:500), MyoD (Santa cruz sc-32758 ...
• Fructose 1,6-bisphosphate sensing by pyruvate kinase isozymes M2 (PKM2) controls MyoD stability and myogenic differentiation

  Minchul Kim, Yao Zhang, Carmen Birchmeier, bioRxiv - Cell Biology 2020

  Quote: ... MyoD (Santa cruz sc-32758, 1:250), β-actin (Cell Signaling 4970 ...
• UV damage induces G3BP1-dependent stress granule formation that is not driven by translation arrest via mTOR inhibition

  Shan Ying, Denys A. Khaperskyy, bioRxiv - Cell Biology 2020

  Quote: ... TIA-1 (Goat, Santa Cruz, sc-1751); TIAR (Rabbit ...
• Moderate and intensive mechanical loading differentially modulate the phenotype of tendon stem/progenitor cells in vivo

  Jianying Zhang, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-Runx2 (1:200, Santa Cruz Biotechnology ...
• Genetic manipulation using hepatocyte-targeting adeno-associated viral vectors has minimal off-target effects

  Christos Kiourtis, et al., bioRxiv - Cell Biology 2021

  Quote: ... and HNF4a (Santa Cruz, sc6556, 1:40) overnight at 4 °C ...
• A complex of BRCA2 and PP2A-B56 is required for DNA repair by homologous recombination

  Sara Marie Ambjoern, et al., bioRxiv - Cell Biology 2021

  Quote: ... GAPDH (Sc-25778, Santa Cruz, 1:5000), tubulin (Ab6160 ...
• A complex of BRCA2 and PP2A-B56 is required for DNA repair by homologous recombination

  Sara Marie Ambjoern, et al., bioRxiv - Cell Biology 2021

  Quote: ... Myc (Sc-40, Santa Cruz, 1:750), PALB2 (A301-246A – M ...
• Restore mitophagy is essential to prevent cardiac oxidative stress during hypertrophy

  Victoriane Peugnet, et al., bioRxiv - Cell Biology 2021

  Quote: ... GAPDH (sc-365062, Santa Cruz, 1/10000), LC3 B (2775 ...
• “Roles for ELMOD2 and Rootletin in Ciliogenesis”

  Rachel E. Turn, et al., bioRxiv - Cell Biology 2021

  Quote: ... Cep164 (1:100) (Santa Cruz; sc-515403), CP110 (1:100 ...
• Small mitochondrial protein NERCLIN regulates cardiolipin homeostasis and mitochondrial ultrastructure

  Svetlana Konovalova, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-TOM40 1:1000 (Santa Cruz 11414); anti-OPA1 1:1000 (BD Biosciences 612606) ...
• Small mitochondrial protein NERCLIN regulates cardiolipin homeostasis and mitochondrial ultrastructure

  Svetlana Konovalova, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-HSP60 1:2000 (Santa Cruz 1052); anti-LC3B 1:1000 (Novus biologicals 600-1384) ...
• Functional differences drive the selection of NRAS mutants in melanoma

  Brandon M. Murphy, et al., bioRxiv - Cancer Biology 2021

  Quote: ... BRAF (1:500, Santa Cruz sc-5284), or CRAF (1:500 ...
• Defining the Ligand-dependent Interactome of the Sigma 1 Receptor

  Jing Zhao, et al., bioRxiv - Cell Biology 2022

  Quote: ... Gapdh (Santa Cruz; 1:2000 for western).
• Ethanol exposure alters Alzheimer’s-related pathology, behavior, and metabolism in APP/PS1 mice

  Stephen C. Gironda, et al., bioRxiv - Neuroscience 2022

  Quote: ... GABAAR α5 (Santa Cruz; Sc393921; 1:1000), and β-actin (Millipore ...