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2601 - 2650 of 8510 citations for 6 Chloro 2 3 diphenylimidazo 1 2 b pyridazine since 2019

• The RNA binding proteins LARP4A and LARP4B promote sarcoma and carcinoma growth and metastasis

  Jennifer C. Coleman, et al., bioRxiv - Cancer Biology 2023

  Quote: ... TOM20 (Santa Cruz, sc-17724, 1:200). Secondary antibodies/stains ...
• Development of an Accelerated Cellular Model for Alzheimer’s Disease

  Huijing Xue, et al., bioRxiv - Cell Biology 2023

  Quote: ... total tau antibody (Santa Cruz, 1:200), PHF6 p-tau antibody (Santa Cruz ...
• Development of an Accelerated Cellular Model for Alzheimer’s Disease

  Huijing Xue, et al., bioRxiv - Cell Biology 2023

  Quote: ... Lamin B1 antibody (Santa Cruz, 1:200); APP antibody (BioLegend ...
• Development of an Accelerated Cellular Model for Alzheimer’s Disease

  Huijing Xue, et al., bioRxiv - Cell Biology 2023

  Quote: ... Lamin B1 antibody (Santa Cruz, 1:200). Secondary antibodies include ...
• RAD52 prevents accumulation of Polα-dependent replication gaps at perturbed replication forks in human cells

  Ludovica Di Biagi, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-MUS81 (Santa Cruz Biotechnology, 1:1000), anti-LAMIN B1 (Abcam ...
• Uip4 governs growth phase dependent organelle remodeling by modulating Saccharomyces cerevisiae lipidome

  Pallavi Deolal, et al., bioRxiv - Cell Biology 2023

  Quote: ... Actin (Santa Cruz sc-47778, 1:5000) and tubulin (Abcam ab6160 ...
• PAK1-dependant mechanotransduction enables myofibroblast nuclear adaptation and chromatin organisation during fibrosis

  Elliot Jokl, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-LMNB1 (374015, Santa Cruz, 1:1000), anti-H3K9Me3 (CST/13969 ...
• Wat1/mLst8, a TOR complex protein regulates mitochondrial integrity and calcium ion homeostasis in fission yeast S. pombe

  Simmi Anjum, et al., bioRxiv - Cell Biology 2023

  Quote: ... or anti-mLst8 (1:1000, Santa Cruz) antibodies ...
• Lack of mTORC2 signaling in CD11c⁺ myeloid cells inhibits their migration and ameliorates experimental colitis

  Aline Ignacio, et al., bioRxiv - Immunology 2023

  Quote: ... -pJNK (1:500, Santa Cruz Biotechnology Inc), -β-actin (1 ...
• PRMT1 is a critical dependency in clear cell renal cell carcinoma through its role in post-transcriptional regulation of DNA damage response genes

  Joseph Walton, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Tubulin (Santa Cruz #sc-5286, 1:1000), Histone H4 (Abcam ...
• Cleavage of the pseudoprotease iRhom2 by the signal peptidase complex reveals an ER-to-nucleus signalling pathway

  Iqbal Dulloo, et al., bioRxiv - Cell Biology 2022

  Quote: ... TFIID (Santa Cruz, #sc-273; 1:1000), Histone H3 (Cell Signaling ...
• Early and late chaperone intervention therapy boosts XBP1s and ADAM10, restores proteostasis, and rescues learning in Alzheimer’s Disease mice

  Jennifer M. Hafycz, et al., bioRxiv - Neuroscience 2023

  Quote: ... β-Actin (1:2000, Santa Cruz sc-47778); GluR1 (1:500 ...
• Liver regeneration by a population of midzone-located mesenchymal-hepatocyte hybrid cells

  Guo Yu, et al., bioRxiv - Cell Biology 2023

  Quote: ... Actin (1:5000, Santa Cruz Biotechnology, 81178).
• Nucleoporin93 (Nup93) Limits Yap Activity to Prevent Endothelial Cell Senescence

  Tung D. Nguyen, et al., bioRxiv - Physiology 2023

  Quote: ... anti-Yap (1:1000, Santa Cruz, sc101199); anti-RelA (1:1000 ...
• Nucleoporin93 (Nup93) Limits Yap Activity to Prevent Endothelial Cell Senescence

  Tung D. Nguyen, et al., bioRxiv - Physiology 2023

  Quote: ... anti-Yap (1:200, Santa Cruz, sc101199); anti-VWF (1:200 ...
• Autophagosome development and chloroplast segmentation occur synchronously for piecemeal degradation of chloroplasts

  Masanori Izumi, et al., bioRxiv - Plant Biology 2023

  Quote: ... containing 1 µM concanamycin A (Santa Cruz) for 1 d in darkness at 23°C ...
• Coupling of Nuclear Translocation to Cell Size Promotes Robustness to Fluctuations in YAP/TAZ Concentration

  Ian Jones, et al., bioRxiv - Cell Biology 2023

  Quote: ... YAP/TAZ [67.3] (Santa Cruz, 1:1000). All the primary antibodies immunostainings were performed overnight at 4°C ...
• PP2B-dependent cerebellar plasticity sets the amplitude of an innate reflex during juvenile development

  Bin Wu, et al., bioRxiv - Neuroscience 2024

  Quote: ... Dyn1 (1:1000, mouse monoclonal, Santa cruz), and probed with secondary antibodies subsequently ...
• ER-to-lysosome Ca²⁺ refilling followed by K⁺ efflux-coupled store-operated Ca²⁺ entry in inflammasome activation and metabolic inflammation

  Hyereen Kang, et al., bioRxiv - Immunology 2023

  Quote: ... HSP 90 (Santa Cruz sc13119, 1: 1,000) and β-actin (Santa Cruz sc47778 ...
• Traitor-virus-guided discovery of novel antiviral factors

  Caterina Prelli Bozzo, et al., bioRxiv - Microbiology 2023

  Quote: ... GBP5 (Santa Cruz #sc-1603539, 1:200), CEACAM3 (Abcam #ab196606 ...
• Traitor-virus-guided discovery of novel antiviral factors

  Caterina Prelli Bozzo, et al., bioRxiv - Microbiology 2023

  Quote: ... IFI16 (Santa Cruz #sc-8023, 1:150), RHOA (Abcam #ab54835 ...
• Traitor-virus-guided discovery of novel antiviral factors

  Caterina Prelli Bozzo, et al., bioRxiv - Microbiology 2023

  Quote: ... CIITA (Santa Cruz #sc-13556, 1:200), EHMT2 (Cell Signalling #3306 ...
• The Inflammasome Pathway is Activated by Dengue Virus Non-structural Protein 1 and is Protective During Dengue Virus Infection

  Marcus P. Wong, et al., bioRxiv - Immunology 2023

  Quote: ... 1:2000 (Santa Cruz Biotechnologies, sc-8432).
• Altered chromatin occupancy of patient-associated H4 mutants misregulate neuronal differentiation

  Lijuan Feng, et al., bioRxiv - Molecular Biology 2023

  Quote: ... DAXX (Santa Cruz, sc-8043, 1:200), Goat anti-Rabbit Alexa Fluor 488/568/647 (Invitrogen ...
• Altered chromatin occupancy of patient-associated H4 mutants misregulate neuronal differentiation

  Lijuan Feng, et al., bioRxiv - Molecular Biology 2023

  Quote: ... ATRX (Santa Cruz, sc-15408, 1:200), DAXX (Santa Cruz ...
• Regulation of BACH1 by hemin improves cardiac function in a mouse model of myocardial infarction

  Valeria Alvino, et al., bioRxiv - Molecular Biology 2023

  Quote: ... DAPI (1:1,000 dilution, Santa Cruz Biotechnologies) was used to stain the nuclei ...
• Regulation of BACH1 by hemin improves cardiac function in a mouse model of myocardial infarction

  Valeria Alvino, et al., bioRxiv - Molecular Biology 2023

  Quote: ... DAPI (1:1,000 dilution, Santa Cruz Biotechnologies) was used to stain the nuclei ...
• The Interferon-inducible NAMPT acts as a protein phosphoribosylase to restrict viral infection

  Shu Zhang, et al., bioRxiv - Molecular Biology 2023

  Quote: ... Alix (1:1000, Santa Cruz, sc-53540), CD63 (1:1000 ...
• POU5F1B is a human-restricted ROCK inhibitor-sensitive oncoprotein that restructures membrane nanodomains to increase cell adhesion

  Laia Simó-Riudalbas, et al., bioRxiv - Cancer Biology 2023

  Quote: ... caveolin1 (Santa Cruz sc-894, 1:500) and transferrin receptor (ThermoFisher 13-6800 ...
• Fibrillar adhesion dynamics govern the timescales of nuclear mechano-response via the vimentin cytoskeleton

  Amy E.M. Beedle, et al., bioRxiv - Biophysics 2023

  Quote: ... Twist (1:100, SC-81417, Santa Cruz). Snail (1:50 ...
• Fibrillar adhesion dynamics govern the timescales of nuclear mechano-response via the vimentin cytoskeleton

  Amy E.M. Beedle, et al., bioRxiv - Biophysics 2023

  Quote: YAP (1:300, sc-101199, Santa Cruz) or (1:300 ...
• Leishmania PNUTS discriminates between PP1 catalytic subunits through a RVxF-ΦΦ-F motif and polymorphisms in the PP1 C-tail and catalytic domain

  Yang Zhang, Robert Sabatini, bioRxiv - Biochemistry 2023

  Quote: ... anti-MYC (Santa Cruz, 9E10, 1:1000), anti-HA antibodies (Sigma ...
• Cyclin A/Cdk1 promotes chromosome alignment and timely mitotic progression

  Sarah Y. Valles, et al., bioRxiv - Cell Biology 2023

  Quote: ... GAPDH (1:1000; Santa Cruz; sc-365062), H3pS10 (1:1000 ...
• Human Papillomavirus 16 replication converts SAMHD1 into a homologous recombination factor and promotes its recruitment to replicating viral DNA

  Claire D. James, et al., bioRxiv - Cancer Biology 2023

  Quote: ... GAPDH 1/10,000 (Santa Cruz, sc-47724), HA-Tag (Abcam ...
• A biomechanical switch promotes lysosomal remodelling and exocytosis in keloid fibroblasts

  Rosie Ross, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-LAMP2 (Santa Cruz H4B4 [1:100]), and anti-LAMP1-LD (R&D Systems AF4800 [1:100]) ...
• Activation of the mitochondrial unfolded protein response regulates the dynamic formation of stress granules

  Marta Lopez-Nieto Jordana, et al., bioRxiv - Cell Biology 2023

  Quote: ... goat anti-eIF3η (1:2000, Santa Cruz) and anti-eIF3A (1:2000 ...
• The CD36 scavenger receptor Bez regulates lipid redistribution from fat body to oocytes in Drosophila

  Pilar Carrera, et al., bioRxiv - Developmental Biology 2023

  Quote: ... mouse anti-RFP (1:200; Santa Cruz), goat anti-E-cadherin (1:100 ...
• Programmed withdrawal of cilia maintenance followed by centriole capping leads to permanent cilia loss during cerebellar granule cell neurogenesis

  Sandii Constable, et al., bioRxiv - Cell Biology 2023

  Quote: ... γTUB (1:500, Santa Cruz #sc-17787), P27KIP (1:400 ...
• ER-to-lysosome Ca²⁺ refilling followed by K⁺ efflux-coupled store-operated Ca²⁺ entry in inflammasome activation and metabolic inflammation

  Hyereen Kang, et al., bioRxiv - Immunology 2023

  Quote: ... and VAP-A (Santa Cruz, 1:200), or with those to KCNN4 (Invitrogen ...
• SART1 localizes to spindle poles forming a SART1 cap and promotes spindle pole assembly

  Hideki Yokoyama, et al., bioRxiv - Cell Biology 2023

  Quote: ... GAPDH (Ms, Santa Cruz, WB 1:2000), Ndc80 (Ms ...
• The kinesin motor Kif9 regulates centriolar satellite positioning and mitotic progression

  Juan Jesus Vicente, et al., bioRxiv - Cell Biology 2024

  Quote: ... mouse-anti-CenpE (1:500, Santa Cruz). All the antibodies were applied overnight at 4 °C ...
• Rit2 silencing in dopamine neurons drives a Parkinsonian phenotype

  Patrick J. Kearney, et al., bioRxiv - Neuroscience 2023

  Quote: ... mouse anti-actin (Santa Cruz, 1:5000). Secondary antibodies conjugated to horseradish peroxidase were all from Jackson ImmunoResearch and immunoreactive bands were visualized by chemiluminescence using SuperSignal West Dura (Thermo Scientific) ...
• Nucleoporin93 (Nup93) Limits Yap Activity to Prevent Endothelial Cell Senescence

  Tung D. Nguyen, et al., bioRxiv - Physiology 2023

  Quote: ... anti-Yap (1:250, Santa Cruz, sc101199); anti-GFP (1:250 ...
• Nucleoporin93 (Nup93) Limits Yap Activity to Prevent Endothelial Cell Senescence

  Tung D. Nguyen, et al., bioRxiv - Physiology 2023

  Quote: ... anti-GFP (1:250, Santa Cruz, sc9996). Cells were then incubated with corresponding AlexaFluor secondary antibodies (2 hours ...
• NCLX controls hepatic mitochondrial Ca²⁺ extrusion and couples hormone-mediated mitochondrial Ca²⁺ oscillations with gluconeogenesis

  Mahmoud Taha, et al., bioRxiv - Physiology 2024

  Quote: ... MCU (1:1000, sc-515930, Santa Cruz) and VDAC1 (1:500 ...
• NCLX controls hepatic mitochondrial Ca²⁺ extrusion and couples hormone-mediated mitochondrial Ca²⁺ oscillations with gluconeogenesis

  Mahmoud Taha, et al., bioRxiv - Physiology 2024

  Quote: ... Sigma-Aldrich),1 µM dexamethasone (SC-29059, Santa Cruz) and100 nM insulin (Actrapid ...
• Sensory perception of fluctuating light in Arabidopsis

  Antonela Belmonte, et al., bioRxiv - Plant Biology 2024

  Quote: ... anti-CHS (Santa Cruz Biotechnology, 1:10000), and anti-Actin (A0480 ...
• Cardiac Localized Polycystin-2 plays a Functional Role in Natriuretic Peptide Production and its Absence Contributes to Hypertension

  Brandon Elliott, et al., bioRxiv - Physiology 2024

  Quote: ... atrial natriuretic peptide (1:100; Santa Cruz), B-type natriuretic peptide (1:100 ...
• Structural basis for coupling of the WASH subunit FAM21 with the endosomal SNX27-Retromer complex

  Qian Guo, et al., bioRxiv - Cell Biology 2024

  Quote: ... DMT-1(sc-166884, Santa Cruz Biotechnology) (1:1,000 for WB) ...
• Atypical Cell Cycle Regulation Promotes Mammary Stem Cell Expansion and Therapeutic Resistance

  Bre-Anne Fifield, et al., bioRxiv - Cancer Biology 2024

  Quote: ... PCNA (1:500; sc-9857; Santa Cruz); cleaved caspase-3 (1:250 ...