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2251 - 2300 of 8510 citations for 6 Chloro 2 3 diphenylimidazo 1 2 b pyridazine since 2019

• Arginine 65 methylation of Neurogenin 3 by PRMT1 is a prerequisite for development of hESCs into pancreatic endocrine cells

  Gahyang Cho, et al., bioRxiv - Developmental Biology 2022

  Quote: ... goat anti-OCT4 (1:500, Santa Cruz), mouse anti-TRA 1–81 (1:200 ...
• In vivo inactivation of RAD51-mediated homologous recombination leads to premature aging, but not to tumorigenesis

  Gabriel Matos-Rodrigues, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-PLZF (1:50, Santa Cruz #SC22839), anti-cCasp3 (1:100 ...
• Maintaining hypoxia environment of subchondral bone alleviates osteoarthritis progression

  Hao Zhang, et al., bioRxiv - Biochemistry 2022

  Quote: ... EMCN (1:50; Santa Cruz, sc-65495) was obtained from Santa Cruz (Dallas ...
• The Batten disease protein CLN3 is important for stress granules dynamics and translational activity

  Emily L. Relton, et al., bioRxiv - Molecular Biology 2022

  Quote: ... Goat anti-eIF3B (1:600, Santa Cruz), mouse anti puromycin (1:5 ...
• The Batten disease protein CLN3 is important for stress granules dynamics and translational activity

  Emily L. Relton, et al., bioRxiv - Molecular Biology 2022

  Quote: ... goat anti-eIF3B (1:2,000, Santa Cruz). mouse anti-GAPDH (1:20,000 ...
• Filopodia-mediated basement membrane assembly at pre-invasive tumor boundaries

  Emilia Peuhu, et al., bioRxiv - Cell Biology 2022

  Quote: ... Vimentin (Clone V9, Santa Cruz, 1:200), Cleaved caspase-3 (Asp175 ...
• Chromatin-modifying enzymes as modulators of nuclear size during lineage differentiation

  Lingjun Meng, bioRxiv - Cancer Biology 2022

  Quote: ... Goat anti-Sox2 (Santa Cruz, 1:200). After staining with corresponding secondary antibodies in PBS plus 1% BSA ...
• iPSC-based modeling of THD recapitulates disease phenotypes and reveals neuronal malformation

  Alba Tristán-Noguero, et al., bioRxiv - Neuroscience 2022

  Quote: ... rabbit anti-TH (1:250; Santa Cruz), mouse anti-Tra-1-60 (1:100 ...
• Exploring the link between Parkinson’s disease and Diabetes Mellitus in Drosophila

  Francisco José Sanz, et al., bioRxiv - Neuroscience 2022

  Quote: ... and β-actin (1:1000, Santa Cruz). Secondary antibodies used were anti-rabbit or anti-mouse HRP-conjugated (1:5000 ...
• The scaffolding protein Flot2 regulates cytoneme-based transport of Wnt3 in gastric cancer

  Daniel Routledge, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-Myosin-X (Santa Cruz C-1), anti-Evi (EMD Milipore YJ5) ...
• A Morphogenetic Wave that Generates Mesenchymal-to-Epithelial Transition in the Lateral Plate Mesoderm

  Manar Abboud Asleh, et al., bioRxiv - Cell Biology 2022

  Quote: ... mouse anti-aPKC (1:500, Santa Cruz), rat anti-RFP (1:1000 ...
• Impaired Lef1 activation accelerates iPSC-derived keratinocytes differentiation in Hutchinson-Gilford Progeria Syndrome

  Xiaojing Mao, et al., bioRxiv - Developmental Biology 2022

  Quote: ... LEF1 (1:250, Santa Cruz sc-374412) and β-actin (1:1000 ...
• Arginine 65 methylation of Neurogenin 3 by PRMT1 is a prerequisite for development of hESCs into pancreatic endocrine cells

  Gahyang Cho, et al., bioRxiv - Developmental Biology 2022

  Quote: ... mouse anti-FLAG (1:500, Santa Cruz), rabbit anti-AMDA (1:500 ...
• Innovative multidimensional models in a high-throughput-format for different cell types of endocrine origin

  Stefan Bornstein, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Chromagranin A (1:100, Santa Cruz Biotechnology), donkey anti-goat-Cy3 (1:500 ...
• Targeted protein S-nitrosylation of ACE2 as potential treatment to prevent spread of SARS-CoV-2 infection

  Chang-ki Oh, et al., bioRxiv - Microbiology 2022

  Quote: ... TMPRSS2 (1:1000, Santa Cruz, sc-515727), or SARS-CoV-2 Spike protein (1:2000 ...
• Lis1-dynein drives corona compaction and error-correction at kinetochores

  Olivera Mitevska, Pak Wing Lam, Philip Auckland, bioRxiv - Cell Biology 2022

  Quote: ... anti-Lis1 (1/400, Mouse, Santa Cruz), anti-ZW10 (1/1000 ...
• Lis1-dynein drives corona compaction and error-correction at kinetochores

  Olivera Mitevska, Pak Wing Lam, Philip Auckland, bioRxiv - Cell Biology 2022

  Quote: ... anti-Mad2 (1/1000, Mouse, Santa Cruz), anti-Lis1 (1/400 ...
• Ubiquitin ligase TRAIP plays an essential role during the S-phase of unperturbed cell cycle in the resolution of DNA replication – transcription conflicts

  Shaun Scaramuzza, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-MCM7 (Santa Cruz 9966; 1:500), anti-BrdU (Sigma-Aldrich ...
• Polyalanine disease mutations impair UBA6-dependent ubiquitination

  Fatima Amer-Sarsour, et al., bioRxiv - Cell Biology 2022

  Quote: ... mouse anti-MATH-1 (Santa Cruz 136173), mouse anti-PRPH (Santa Cruz 377093) ...
• Nuclear receptor interaction protein (NRIP) as a novel actin-binding protein involved in invadosome formation for myoblast fusion

  Hsin-Hsiung Chen, et al., bioRxiv - Cell Biology 2022

  Quote: ... and anti-GFP (Santa Cruz, 1:20)] at 4°C overnight ...
• Defining the Ligand-dependent Interactome of the Sigma 1 Receptor

  Jing Zhao, et al., bioRxiv - Cell Biology 2022

  Quote: ... Sec61alpha (Santa Cruz; 1:100 for western); Sigma1 Receptor (1:500 for western ...
• Tropism of SARS-CoV-2 for Developing Human Cortical Astrocytes

  Madeline G. Andrews, et al., bioRxiv - Neuroscience 2021

  Quote: ... Sox2 (Santa Cruz, sc-365823, 1:500), S100B (Sigma ...
• Enforced dimerization between XBP1s and ATF6f enhances the protective effects of the unfolded protein response (UPR) in models of neurodegeneration

  René L. Vidal, et al., bioRxiv - Neuroscience 2020

  Quote: ... beta-actin (1:3,000; Santa Cruz Biotechnology), TH (1:2,000 ...
• Fibrillar Aβ triggers microglial proteome alterations and dysfunction in Alzheimer mouse models

  Laura Sebastian Monasor, et al., bioRxiv - Neuroscience 2019

  Quote: ... NAB228 (1:2000, sc-32277, Santa Cruz), CD68 (1:500 ...
• Atxn2-CAG100-KnockIn mouse spinal cord shows progressive TDP43 pathology associated with cholesterol biosynthesis suppression

  Júlia Canet-Pons, et al., bioRxiv - Neuroscience 2019

  Quote: ... TIA1 (Santa Cruz sc-1751, 1:100). Secondary antibodies used were ...
• YAP/TAZ Maintain the Proliferative Capacity and Structural Organization of Radial Glial Cells During Brain Development

  Alfonso Lavado, et al., bioRxiv - Developmental Biology 2021

  Quote: ... SOX2 (Santa Cruz Biotechnology #SC17320, 1:100), SOX2–Alexa-647 (BD Biosciences #562139 ...
• FOXO1 represses Sprouty2 and Sprouty4 expression in endothelial cells to promote arterial specification and vascular remodeling in the mouse yolk sac

  Nanbing Li-Villarreal, et al., bioRxiv - Developmental Biology 2021

  Quote: ... eNOS (Santa Cruz #sc-654, 1:50); Flk1 (Sigma #V1014 ...
• H3 acetylation selectively promotes basal progenitor proliferation and neocortex expansion by activating TRNP1 expression

  Cemil Kerimoglu, et al., bioRxiv - Developmental Biology 2021

  Quote: ... BAF155 mouse mAb (1:100; Santa Cruz), CASP3 rabbit pAb (1:100 ...
• Continual reelin signaling by the prime neurogenic niche of the adult brain

  F. Javier Pérez-Martínez, et al., bioRxiv - Neuroscience 2021

  Quote: ... goat anti-doublecortin (Santa Cruz, 1:100), rabbit anti-GFAP (Dako ...
• Cell-type specific in vitro gene expression profiling of stem-cell derived neural models

  James A. Gregory, et al., bioRxiv - Molecular Biology 2020

  Quote: ... SOX2 (Santa Cruz, #sc-365823, 1:100), and B-tubulin III (Sigma ...
• Werner syndrome protein (WRN) regulates cell proliferation and the human papillomavirus 16 life cycle during epithelial differentiation

  Claire D. James, et al., bioRxiv - Molecular Biology 2020

  Quote: ... Keratin-10 (1/2000, Santa Cruz Biotechnology), BrdU (1/200 ...
• The regenerating skeletal muscle niche guides muscle stem cell self-renewal

  Alicia A. Cutler, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-parD3 1:200 (Santa Cruz Biotechnology), anti-phospho histone 3 1:500 (Millipore)] were incubated with intact myofibers at room temperature for 1h followed by three washes in PBS ...
• Angiocrine IGFBP3 Spatially Coordinates IGF Signaling During Neonatal Cardiac Regeneration

  Shah R. Ali, et al., bioRxiv - Cell Biology 2021

  Quote: ... Igfbp3 (Santa Cruz, sc-9028; 1:100). DAPI or Hoechst was used for nuclear staining ...
• SGLT2 inhibitors therapy protects glucotoxicity-induced β-cell failure in a mouse model of human K_ATP-induced diabetes trough mitigation of oxidative and ER stress

  Zeenat A. Shyr, et al., bioRxiv - Cell Biology 2021

  Quote: ... SERCA2b (1:1000, Santa Cruz Biotechnology, TX). Blots were washed and probed with RDye infrared fluorescent dye-labeled secondary antibody conjugates (1:10,000 ...
• SGLT2 inhibitors therapy protects glucotoxicity-induced β-cell failure in a mouse model of human K_ATP-induced diabetes trough mitigation of oxidative and ER stress

  Zeenat A. Shyr, et al., bioRxiv - Cell Biology 2021

  Quote: ... sXBP1 (1:1000; Santa Cruz Biotechnology, TX), Prohormone convertase 1/3 (1:1000 ...
• Angiocrine IGFBP3 Spatially Coordinates IGF Signaling During Neonatal Cardiac Regeneration

  Shah R. Ali, et al., bioRxiv - Cell Biology 2021

  Quote: ... endomucin (Santa Cruz, V.7C7; 1:1250); Pappa2 (Thermo Scientific ...
• Epithelial-mesenchymal plasticity induced by discontinuous exposure to TGFβ1 promotes tumour growth

  Mafalda Santos, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-Fibronectin (1:50,Santa Cruz,USA) and anti-rabbit/anti-mouse Alexa 488/594 (1:500,ThermoFisher,USA) ...
• Multiple viral microRNAs regulate interferon release and signaling early during infection with Epstein-Barr virus

  Mickaël Bouvet, et al., bioRxiv - Microbiology 2020

  Quote: ... TLR9 (Santa Cruz, # sc-47723, 1 :200), IFIT1 (abcam ...
• Global kinome silencing combined with 3D invasion screening of the tumor microenvironment identifies fibroblast-expressed PIK3Cδ involvement in triple-negative breast cancer progression

  Teresa Gagliano, et al., bioRxiv - Cancer Biology 2019

  Quote: ... PIK3Cδ (Santa Cruz, sc-55589, 1:30), pAkt-S473 (Cell Signaling Technology ...
• Fast Transport of RNA Granules by Direct Interactions with KIF5A/KLC1 Motors Prevents Axon Degeneration

  Yusuke Fukuda, et al., bioRxiv - Cell Biology 2020

  Quote: ... mouse anti-Myc (1:500; Santa Cruz), mouse anti-FLAG (1:1000 ...
• Endogenous neural stem cells modulate microglia and protect from demyelination

  Béatrice Brousse, et al., bioRxiv - Neuroscience 2020

  Quote: ... goat anti-DCX (1/250; Santa Cruz), anti-Nestin (1/100 ...
• Transposon mutagenesis identifies cooperating genetic drivers during keratinocyte transformation and cutaneous squamous cell carcinoma progression

  Aziz Aiderus, et al., bioRxiv - Cancer Biology 2020

  Quote: ... GAPDH (1:5000, Santa Cruz sc-69778), anti-mouse and anti-goat secondary antibodies (1:10000 ...
• TRAF4 inhibits bladder cancer progression by promoting BMP/SMAD signalling pathway

  Prasanna Vasudevan Iyengar, et al., bioRxiv - Cancer Biology 2020

  Quote: ... SMURF1 1:1000 (45-K, Santa Cruz), Myc 1:5000 (9E10 ...
• O-GlcNAc transferase regulates glioblastoma acetate metabolism via regulation of CDK5-dependent ACSS2 phosphorylation

  Lorela Ciraku, et al., bioRxiv - Cancer Biology 2021

  Quote: ... O-GlcNAc RL2 (Santa Cruz 1:50), p-S267 ACSS2 (1:100 ...
• mTOR signaling regulates the morphology and migration of outer radial glia in developing human cortex

  Madeline G. Andrews, et al., bioRxiv - Neuroscience 2020

  Quote: ... Cofilin (Santa Cruz, sc-376476, 1:100), Cdc42 (Santa Cruz ...
• mTOR signaling regulates the morphology and migration of outer radial glia in developing human cortex

  Madeline G. Andrews, et al., bioRxiv - Neuroscience 2020

  Quote: ... Hopx (Santa Cruz, sc-398703, 1:250), Cofilin (Santa Cruz ...
• High resolution mouse subventricular zone stem cell niche transcriptome reveals features of lineage, anatomy, and aging

  Xuanhua P. Xie, et al., bioRxiv - Neuroscience 2020

  Quote: ... goat anti-Doublecortin (Santa Cruz, 1:500), goat anti-Sox2 (Santa Cruz ...
• Modeling human age-associated increase in Gadd45γ expression leads to spatial recognition memory impairments in young adult mice

  David V.C. Brito, et al., bioRxiv - Neuroscience 2020

  Quote: ... β-Actin (1:1000, Santa Cruz, #SC-47778) or α-Tubulin (1:40000 ...
• Robotic High-Throughput Biomanufacturing and Functional Differentiation of Human Pluripotent Stem Cells

  Carlos A. Tristan, et al., bioRxiv - Bioengineering 2020

  Quote: ... HNF4a (Santa Cruz, sc-6556, 1:250), AFP (Sigma ...
• Chromatin-Bound PARP1 Correlates with Upregulation of Inflammatory Genes in Response to Long-Term Treatment with Veliparib

  Isabel Alvarado-Cruz, et al., bioRxiv - Cancer Biology 2020

  Quote: ... PARP1 (sc-7150; Santa Cruz,1:500), anti-mouse (NXA931V ...