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6851 - 6900 of 8862 citations for 6 1 4 dioxa 8 azaspiro 4.5 decan 8 yl 3 hydroxy 2 iminopyrimidin 4 amine since 2019

• Pharmacologically diverse antidepressant drugs disrupt the interaction of BDNF receptor TRKB and the endocytic adaptor AP-2

  Senem Merve Fred, et al., bioRxiv - Pharmacology and Toxicology 2019

  Quote: ... the secondary antibody against AP2M was added (1:2000, #sc-515920, Santa Cruz) ON at 4°C under agitation ...
• Regulation of HDAC2-PDX1 by RNF125 defines pancreatic cancer development

  Erez Hasnis, et al., bioRxiv - Cancer Biology 2020

  Quote: ... alpha smooth muscle actin (αSMA, Santa Cruz; #sc-53015, IHC dilution 1:100), PDX1 (Cell Signaling ...
• The Role of the Wnt/PCP Formin Daam1 in Renal Ciliogenesis

  Mark E. Corkins, et al., bioRxiv - Molecular Biology 2019

  Quote: ... Blots were incubated in 1:1000 rabbit anti-GAPDH (Santa Cruz sc-25778), 1:1000 rabbit anti-Daam1 (Protein Tech 14876-1-AP ...
• VE-cadherin endocytosis controls vascular integrity and patterning during development

  Cynthia M. Grimsley-Myers, et al., bioRxiv - Cell Biology 2019

  Quote: ... rabbit anti-p120 (S-19; Santa Cruz Biotechnology, Inc #sc-1101; 1:750), mouse anti-beta-catenin (BD Biosciences #610153 ...
• VE-cadherin endocytosis controls vascular integrity and patterning during development

  Cynthia M. Grimsley-Myers, et al., bioRxiv - Cell Biology 2019

  Quote: ... rabbit anti-p120 (S-19, Santa Cruz Biotechnology, Inc #sc-1101, 1:250); mouse anti-beta-catenin (BD Biosciences #610153 ...
• Enhanced translation expands the endo-lysosome size and promotes antigen presentation during phagocyte activation

  Victoria E. B. Hipolito, et al., bioRxiv - Cell Biology 2019

  Quote: ... cells were incubated in 1:75 mAb YAe (Santa Cruz Biotechnology, Dallas, Tx) in blocking buffer for 1 hour at RT ...
• Systematic multi-omics cell line profiling uncovers principles of Ewing sarcoma fusion oncogene-mediated gene regulation

  Martin F. Orth, et al., bioRxiv - Genomics 2021

  Quote: ... anti-GAPDH raised in mouse (sc-32233, 1:2,000; Santa Cruz, Dallas, USA), polyclonal anti-mouse IgG-HRP raised in goat (W402B ...
• The combined action of CTCF and its testis-specific paralog BORIS is essential for spermatogenesis

  Samuel Rivero-Hinojosa, et al., bioRxiv - Genomics 2021

  Quote: ... and 1:2000 of an anti-mouse secondary antibody (sc-2005, Santa Cruz). Tubulin was detected using 1:5000 anti-α Tubulin B-7 (sc-5286 ...
• A stress-induced Tyrosine tRNA depletion response mediates codon-based translational repression and growth suppression

  Doowon Huh, et al., bioRxiv - Molecular Biology 2020

  Quote: ... Loading controls used were HSC70 (Santa Cruz, sc-7298, RRID: AB_627761, 1:2000). Chemiluminescent signal was detected by HRP-conjugated secondary antibodies ...
• The combined action of CTCF and its testis-specific paralog BORIS is essential for spermatogenesis

  Samuel Rivero-Hinojosa, et al., bioRxiv - Genomics 2021

  Quote: ... and 1:2000 of an anti-mouse secondary antibody (sc-2005, Santa Cruz). Images were quantified using ImageJ (v1.48 ...
• Chloroquine Kills Hair Cells in Zebrafish Lateral Line and Murine Cochlear Cultures: Implications for Ototoxicity

  Samantha N. Davis, et al., bioRxiv - Neuroscience 2020

  Quote: ... and 1:1000 anti-Myosin-VIIa rabbit polyclonal antibody (Santa Cruz, sc-74516), 1:1000 anti-Sox2 polyclonal antibody overnight followed by 1:500 Alexa Fluor 488 and 1:500 Alexa Fluor 694 goat anti-rabbit IgG (Invitrogen ...
• Rotavirus NSP1 contributes to intestinal viral replication, pathogenesis, and transmission

  Gaopeng Hou, et al., bioRxiv - Microbiology 2021

  Quote: ... anti-RV VP6 mouse monoclonal antibody (Santa Cruz Biotechnology, sc-101363, 1:1000), anti-GAPDH rabbit monoclonal antibody (CST ...
• Time-dependent roles of adolescent- and adult-born dentate granule neurons in spatial learning

  Nuria Masachs, et al., bioRxiv - Neuroscience 2020

  Quote: ... Sections were also incubated with rabbit anti-Zif268 (1/500, Santa Cruz Biotechnology). Bound antibodies were visualized with Alexa488-goat anti-rabbit antibodies (1/1,000 ...
• Optogenetic relaxation of actomyosin contractility uncovers mechanistic roles of cortical tension during cytokinesis

  Kei Yamamoto, et al., bioRxiv - Cell Biology 2021

  Quote: ... and α-Tubulin antibody (DM1A) (1:5000 dilution; sc-32293: Santa Cruz Biotechnology) were diluted in Odyssey Blocking Buffer-TBS ...
• Freshly Thawed Cryobanked Human Neural Stem Cells Engraft within Endogenous Neurogenic Niches and Restore Cognitive Function Following Chronic Traumatic Brain Injury

  Anna Badner, et al., bioRxiv - Neuroscience 2020

  Quote: ... polyclonal goat anti-DCX (1:250; sc-8066, Santa Cruz Biotechnology, Dallas, TX), polyclonal rabbit anti-NeuN (1:500 ...
• Massive transient damage of the olfactory epithelium associated with infection of sustentacular cells by SARS-CoV-2 in golden Syrian hamsters

  Bertrand Bryche, et al., bioRxiv - Neuroscience 2020

  Quote: ... G alpha s/olf - Golf (1:500; rabbit polyclonal; Santa Cruz Biotechnology (sc383), Dallas ...
• CD8⁺ T cell immunogenicity induced by endogenous EVs engineered by antigens fused to a truncated Nef^mut EV-anchoring protein

  Chiara Chiozzini, et al., bioRxiv - Bioengineering 2021

  Quote: ... and 1:500 diluted anti-Alix H-270 polyclonal Abs from Santa Cruz.
• Mechanical intercellular communication via matrix-borne cell force transmission during vascular network formation

  Christopher D. Davidson, et al., bioRxiv - Bioengineering 2021

  Quote: ... or mouse monoclonal anti-VE-cadherin antibody (1:1000, Santa Cruz #sc-9989) followed by secondary antibody (1:1000 ...
• Alzheimer’s Aβ assembly binds sodium pump and blocks endothelial NOS activity via ROS-PKC pathway

  Tomoya Sasahara, et al., bioRxiv - Biochemistry 2020

  Quote: ... To detect NAKα3 (anti-NAK antibody; sc-16052, 1:250, Santa Cruz Biotechnology), we increased the applied protein volume (30 μg protein/lane ...
• SYNAPTIC RELEASE POTENTIATION AT AGING AUDITORY RIBBON SYNAPSES

  Thibault Peineau, et al., bioRxiv - Neuroscience 2021

  Quote: ... Synaptic ribbons were labeled with anti-CtBP2 (1/200 Goat polyclonal, Santa Cruz, USA ...
• Aβ promotes amyloidogenic processing of APP through a Go/Gβγ signaling

  Magdalena Antonino, et al., bioRxiv - Neuroscience 2021

  Quote: ... mouse anti-Gαo clone A2 (1:500; Santa Cruz Biotechnology, Dallas, TX, U.S.), mouse anti-GFP clone 3E6 (1:1000 ...
• The microtubule plus-end tracking protein Bik1 is required for chromosome congression

  Alexander Julner, et al., bioRxiv - Cell Biology 2021

  Quote: ... c-Myc rabbit polyclonal antibody (Santa Cruz Biotechnology; sc-789, diluted 1:5000); anti-Pgk1 mouse monoclonal antibody (Invitrogen ...
• Lin28a rejuvenates muscle stem cells via mitochondrial optimization

  Peng Wang, et al., bioRxiv - Cell Biology 2021

  Quote: ... Cells were then immunostained for MyoG (Santa Cruz Biotechnology, sc-12732, 1:100) and MYH1 (clone MF20 ...
• Homophilic and heterophilic cadherin bond rupture forces in homo- or hetero-cellular systems measured by AFM based SCFS

  Prem Kumar Viji Babu, et al., bioRxiv - Biophysics 2020

  Quote: ... anti-OB-cadherin 1:50 dilution (mouse monoclonal; sc-365867, Santa Cruz Biotechnology) and anti-E-cadherin 1:50 dilution (goat polyclonal ...
• Homophilic and heterophilic cadherin bond rupture forces in homo- or hetero-cellular systems measured by AFM based SCFS

  Prem Kumar Viji Babu, et al., bioRxiv - Biophysics 2020

  Quote: ... anti-N-cadherin 1:200 dilution (rabbit polyclonal; sc-7939, Santa Cruz Biotechnology), anti-OB-cadherin 1:50 dilution (mouse monoclonal ...
• Early detection of biomarkers for circulating tumor cells in Bone marrow and Peripheral blood in a fast-progressing gastric cancer model

  Prerna Bali, et al., bioRxiv - Cancer Biology 2020

  Quote: ... and CD117 (c-Kit, 2B, 1:200, Santa Cruz Biotechnologies (Santa Cruz, CA)) ...
• Early detection of biomarkers for circulating tumor cells in Bone marrow and Peripheral blood in a fast-progressing gastric cancer model

  Prerna Bali, et al., bioRxiv - Cancer Biology 2020

  Quote: ... and CD117 (c-Kit, 2B, 1:200, Santa Cruz Biotechnologies (Santa Cruz, CA)) ...
• Membrane metalloendopeptidase suppresses prostate carcinogenesis by attenuating effects of gastrin-releasing peptide on stem/progenitor cells

  Chieh-Yang Cheng, et al., bioRxiv - Cancer Biology 2019

  Quote: ... The primary antibodies to MME (Santa Cruz; Dallas, TX; #sc-80021, 1:100), Ki67 (Leica Microsystems ...
• TAT-Cx43_266-283 impairs metabolic plasticity in glioma stem cells in vitro and in vivo

  Sara G. Pelaz, et al., bioRxiv - Cancer Biology 2019

  Quote: ... mouse monoclonal antibody against RPL-19 (1:200; Santa Cruz Biotechnology, sc-100830), rabbit polyclonal antibody against Sox-2 (1:500 ...
• The Astrin-SKAP Complex Reduces Friction at the Kinetochore-Microtubule Interface

  Miquel Rosas-Salvans, et al., bioRxiv - Cell Biology 2021

  Quote: ... and mouse anti-rabbit IgG-HRP (1:1000, sc-2357, Santa Cruz Biotechnology). Blots were exposed with SuperSignal West Pico Substrate (Thermo Scientific ...
• POMC neurons functional heterogeneity relies on mTORC1 signaling

  Nicolas Saucisse, et al., bioRxiv - Neuroscience 2020

  Quote: ... and then with goat anti-c-Fos antibody (1:250; Santa Cruz Biotechnology) overnight at 4°C ...
• LAMP3 is critical for surfactant homeostasis in mice

  Lars P. Lunding, et al., bioRxiv - Biochemistry 2021

  Quote: ... and anti-β-actin (mouse monoclonal, 1:200, Santa Cruz Biotechnology, Heidelberg, Germany). Donkey anti-rabbit IgG HRP (1:2000 ...
• Enrichment of Zα domains at cytoplasmic stress granules is due to their innate ability to bind nucleic acids

  Luisa Gabriel, et al., bioRxiv - Biochemistry 2021

  Quote: ... anti-TIAR (C-18) (IFA 1:500, ref. SC-1749, Goat, Santa Cruz), anti-NONO (IFA and WB 1:500 ...
• mTOR controls neurotoxic lysosome exocytosis in inflammatory reactive astrocytes

  Brendan Rooney, et al., bioRxiv - Cell Biology 2021

  Quote: ... or EGFP (1:200; mouse monoclonal; Santa Cruz Biotechnology cat. no. sc-9996) at 4°C overnight on a shaker ...
• Epigenetic modulation reveals differentiation state specificity of oncogene addiction

  Mehwish Khaliq, et al., bioRxiv - Systems Biology 2021

  Quote: ... p-RbS807/811 (goat pAb, Santa Cruz Biotechnology, Cat# sc-16670, 1:400), NGFR (rabbit mAb ...
• Endothelial sphingosine-1-phosphate receptor 1 deficiency exacerbates brain injury and blood brain barrier dysfunction upon subarachnoid hemorrhage in mice

  Akira Ito, et al., bioRxiv - Neuroscience 2019

  Quote: ... Immunoblot analysis was performed with S1PR1 (1:250; Santa Cruz, cat. no. sc25489), p-MLC (1:1000 ...
• IPSC-derived midbrain astrocytes from Parkinson’s disease patients carrying pathogenic SNCA mutations exhibit alpha-synuclein aggregation, mitochondrial fragmentation and excess calcium release

  Peter A. Barbuti, et al., bioRxiv - Neuroscience 2020

  Quote: ... The primary antibodies used were anti-ALDH1L1 (1:100; Santa Cruz, sc-100497), GFAP (1:300 ...
• pVHL regulates protein stability of TCF/LEF transcription factor family via ubiquitin-independent proteasomal degradation

  Caixia Wang, et al., bioRxiv - Cell Biology 2021

  Quote: ... mouse anti-pVHL (1:1,000 for western blotting, sc-135657; Santa Cruz Biotechnology), rabbit anti-proteasome 19S S5A (1:1,000 for western blotting ...
• Nwd1 regulates neuronal differentiation and migration through purinosome formation in the developing cerebral cortex

  Seiya Yamada, Ayaka Sato, Shin-ichi Sakakibara, bioRxiv - Neuroscience 2020

  Quote: ... anti-doublecortin (DCX) (goat polyclonal, Santa Cruz, sc-271390; 1:200 for immunostaining), anti-β-tubulin III (chicken polyclonal IgY ...
• The anticoagulant nafamostat potently inhibits SARS-CoV-2 infection in vitro: an existing drug with multiple possible therapeutic effects

  Mizuki Yamamoto, et al., bioRxiv - Microbiology 2020

  Quote: ... and anti-GAPDH (1:1000, sc-25778 Santa Cruz Biotechnology, Dallas, TX, USA). HRP-linked donkey anti-rabbit IgG (NA934 ...
• Salmonella Enteritidis Effector AvrA suppresses autophagy by reducing Beclin-1 protein

  Yang Jiao, et al., bioRxiv - Microbiology 2020

  Quote: ... anti-lysozyme (1:100, sc27958, Santa Cruz Biotechnology, Inc., Santa Cruz, CA, USA), at 4°C overnight ...
• A Cytoskeletal Function for PBRM1 Reading Methylated Microtubules

  Menuka Karki, et al., bioRxiv - Cell Biology 2020

  Quote: ... Secondary antibodies (1:5,000) conjugated to horseradish peroxidase were purchased from Santa Cruz Biotechnology ...
• Direct Supercritical Angle Localization Microscopy for Nanometer 3D Superresolution

  Anindita Dasgupta, et al., bioRxiv - Biophysics 2020

  Quote: ... and 1 µl anti-clathrin light chain rabbit antibody (sc28276, Santa Cruz Biotechnology) were used in 100 µL 50% v/v ImageIT in PBS containing 2% (w/v ...
• Adult porcine (Sus scrofa) derived inner ear cells possessing multipotent stem/progenitor cell characteristics in in vitro cultures

  Printha Wijesinghe, et al., bioRxiv - Cell Biology 2021

  Quote: ... prestin (outer HC marker) 1:100 dilution (goat polyclonal-SC22692, Santa Cruz Biotechnology); nestin (stem/progenitor cell marker ...
• Opposing motors provide mechanical and functional robustness in the human spindle

  Lila Neahring, Nathan H. Cho, Sophie Dumont, bioRxiv - Cell Biology 2021

  Quote: ... and mouse anti-KifC1 (M-63; 1:500, sc-100947, Santa Cruz Biotechnology). The following secondary antibodies were used at a 1:10,000 dilution ...
• Pathogenic variants of sphingomyelin synthase SMS2 disrupt lipid landscapes in the secretory pathway

  Tolulope Sokoya, et al., bioRxiv - Cell Biology 2022

  Quote: ... mouse monoclonal anti-Na/K ATPase (Santa Cruz, sc-48345; IB 1:1,000), rabbit monoclonal anti-Na/K ATPase (Abcam ...
• Neuronal hemoglobin induces loss of dopaminergic neurons in mouse Substantia nigra, cognitive deficits and cleavage of endogenous α-synuclein

  Santulli Chiara, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-α-syn 1:1000 (C-20) (Santa Cruz Biotechnology, sc-7011-R), anti-α-syn 1:1000 (SYN-1 ...
• Genomic instability in patients with sex determination defects and germ cell cancer

  Maria Krivega, et al., bioRxiv - Genetics 2022

  Quote: ... anti-OCT4 mouse monoclonal (1/300 dilution, cat.#SC-5279, Santa Cruz Biotechnology).
• The SARS-CoV-2 spike protein binds and modulates estrogen receptors

  Oscar Solis, et al., bioRxiv - Immunology 2022

  Quote: ... or normal mouse IgG (Santa Cruz Biotech, cat no. sc-2025, 1:200) as a negative control ...
• Pharmacological PP2A reactivation overcomes multikinase inhibitor tolerance across brain tumor cell models

  Oxana V. Denisova, et al., bioRxiv - Cancer Biology 2022

  Quote: ... SV40 T Ag Antibody (Pab 108) (Santa Cruz Biotechnology, sc-148, 1:1000), β-actin (Sigma-Aldrich ...