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7051 - 7100 of 8862 citations for 6 1 4 dioxa 8 azaspiro 4.5 decan 8 yl 3 hydroxy 2 iminopyrimidin 4 amine since 2019

• Harnessing DNA replication stress to target RBM10 deficiency in lung adenocarcinoma

  Feras E. Machour, et al., bioRxiv - Molecular Biology 2023

  Quote: ... and mouse anti-PCNA (Santa Cruz Bio cat. no. sc-56, 1:250) antibodies were incubated for 1 hr at 37°C prior to PLA analysis ...
• Hyaluronic acid turnover controls the severity of Cerebral Cavernous Malformations in bioengineered human micro-vessels

  Teodor E. Yordanov, et al., bioRxiv - Cell Biology 2023

  Quote: Primary antibodies: mouse α-VE-cadherin (WB 1:1000; sc-9989; Santa Cruz), rabbit α-KRIT1 (CCM1 ...
• Generation and characterization of a novel mouse model of Becker Muscular Dystrophy with a deletion of exons 52 to 55

  Lucie O. M. Perillat, et al., bioRxiv - Genetics 2023

  Quote: ... and mouse monoclonal anti-β-actin (sc-47778; Santa Cruz Biotechnology; 1:10,000).
• PPARγ controls ESCRT-dependent fibroblast-like synoviocyte exosome biogenesis and Alleviates Chondrocyte Osteoarthritis Mediated by Exosomal ANXA1

  Shuangshuo Jia, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-Hrs (sc-271455, 1:1000, Santa Cruz Biotechnology, Santa Cruz, CA, USA), STAM1 Antibody (13053 ...
• Host-derived oxidized phospholipids initiate effector-triggered immunity fostering lethality upon microbial encounter

  Marco Di Gioia, et al., bioRxiv - Immunology 2023

  Quote: ... and rat anti-Ly6G/Ly6C (1:50, Santa Cruz Biotechnology, Cat#: dc-59338) overnight at 4°C ...
• The protooncogene Ski regulates the neuron-glia switch during development of the mammalian cerebral cortex

  Alice Grison, et al., bioRxiv - Systems Biology 2022

  Quote: ... We used antibodies against goat Sox2 (1:200; Santa Cruz Biotechnology sc-17320); rat BrdU (1:400 ...
• Sialidases and Fucosidases of Akkermansia muciniphila are crucial for growth on mucin and nutrient sharing with mucus-associated gut bacteria

  Bashar Shuoker, et al., bioRxiv - Biochemistry 2022

  Quote: ... IgM anti-Lewis X antibody: CD15 (C3D-1) (Santa Cruz Biotechnology, sc-19648), IgM anti-Blood Group Lewis Y (F3 ...
• CD9 co-operation with syndecan-1 is required for a major staphylococcal adhesion pathway

  Luke R. Green, et al., bioRxiv - Microbiology 2023

  Quote: ... Mouse anti-human SDC-1 IgG1 (B-A38; Santa Cruz Biotechnology, Texas, USA), mouse anti-human SDC-4 IgG2a (5G9 ...
• Oncomodulin Regulates Spontaneous Calcium Signaling and Maturation of Afferent Innervation in Cochlear Outer Hair Cells

  Yang Yang, et al., bioRxiv - Developmental Biology 2023

  Quote: Samples were stained with antibodies to OCM (Santa Cruz sc-7446, 1:200), P2X2 (alomone lab APR-003 ...
• Sonic Hedgehog Activates Prostaglandin Signaling to Stabilize Primary Cilium Length

  Shariq S. Ansari, et al., bioRxiv - Cell Biology 2023

  Quote: ... The following antibodies and dilutions were used: anti-SMO (Santa Cruz, 1:500), anti-acetylated α-tubulin (Cell Signaling ...
• Piperlongumine (PL) conjugates induce targeted protein degradation

  Jing Pei, et al., bioRxiv - Cancer Biology 2023

  Quote: ... CDK9 antibody was purchased from Santa Cruz (Cat. No. sc-13130, 1:500). V5-tag antibody was purchased from Bethyl (Cat ...
• A flexible loop in the paxillin LIM3 domain mediates direct binding to integrin β3

  Timo Baade, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-human cSRC (rabbit polyclonal, SRC2, Santa Cruz, sc-18; WB 1:1000), anti-human ILK (rabbit monoclonal ...
• Title: β Cell microRNAs Function as Molecular Hubs of Type 1 Diabetes Pathogenesis and as Biomarkers of Diabetes Risk

  Farooq Syed, et al., bioRxiv - Physiology 2023

  Quote: ... and anti-CD9 (1:1000 dilution; cat#SC5275, Santa Cruz, mouse monoclonal, RRID:AB_627877). Anti-rabbit or anti-mouse (1:10000 ...
• Translational approach to social isolation during a global pandemic: Hippocampal somatic mutation

  Bomee Lee, et al., bioRxiv - Neuroscience 2023

  Quote: ... and Δ-actin antibody (1:10000, Santa Cruz biotechnology, mouse, Sc-47778 HRP) for 16h at 4℃ ...
• Enhanced muscle regeneration in mdx mice, Duchenne muscular dystrophy animal model, proven by CD44 & MYH3 expression, on oral feeding of N-163 strain of Aureobasidium Pullulans produced B-Glucan

  Senthilkumar Preethy, et al., bioRxiv - Genetics 2023

  Quote: ... The following antibody was used: Myh3 (sc-53091, Santa Cruz Biotechnology, 1:100). Images were taken with all-in-one fluorescence microscope BZ-X800 (Keyence ...
• Towards Modular Engineering of Cell Signalling: Topographically-Textured Microparticles Induce Osteogenesis via Activation of Canonical Hedgehog Signalling

  Fatmah I. Ghuloum, et al., bioRxiv - Bioengineering 2023

  Quote: ... RUNX2 (27-K) antibody (1:500; sc-101145, Santa Cruz Biotechnology, RRID: AB_1128251), and monoclonal anti-Vinculin (1:70 ...
• Canonical Wnt and TGF-β/BMP signaling enhance melanocyte regeneration and suppress invasiveness, migration, and proliferation of melanoma cells

  Esra Katkat, et al., bioRxiv - Developmental Biology 2023

  Quote: ... mouse anti-vimentin (1:1000, sc-373717, Santa Cruz Biotechnology, Inc. TX, USA). Secondary antibodies were donkey anti-rabbit IgG HRP-linked LICOR IRDye 800CW (1:2000 ...
• Proximity Analysis of Native Proteomes Reveals Interactomes Predictive of Phenotypic Modifiers of Autism and Related Neurodevelopmental Conditions

  Yudong Gao, et al., bioRxiv - Neuroscience 2023

  Quote: ... The membrane was probed for Myc-epitope (Santa Cruz #sc-40, 1:250), V5-epitope (Cell Signaling #13202S ...
• Hemin decreases cellular aging and enhances healthspan and lifespan through the AMPK pathway

  Yizhong Zhang, et al., bioRxiv - Genetics 2023

  Quote: ... followed by goat anti-rat HRP-conjugated antibody (1:5000; Santa Cruz Biotechnology). Blots were developed with ECL prime western blotting detection reagent (Amersham Pharmacia Biotech ...
• Somatic mutation of Afadin leads to anchorage independent survival and metastatic growth of breast cancer through αE-catenin dependent destabilization of the adherens junction

  Max A.K. Ratze, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and goat anti-AKT (1:1,000, C-20/sc-1618; Santa Cruz Biotechnology). All blots were incubated for 30 min ...
• Differential regulation of the proteome and phosphosproteome along the dorso-ventral axis of the early Drosophila embryo

  Juan Manuel Gomez, et al., bioRxiv - Developmental Biology 2023

  Quote: ... mouse anti acetylated-α-tubulin FITC conjugated 1:250 (sc23950, Santa Cruz Biotechnology), rat anti tyrosinated-α-tubulin 1:250 (MAB1864-I ...
• Proximity Analysis of Native Proteomes Reveals Interactomes Predictive of Phenotypic Modifiers of Autism and Related Neurodevelopmental Conditions

  Yudong Gao, et al., bioRxiv - Neuroscience 2023

  Quote: ... the membrane was probed for Myc-epitope (Santa Cruz #sc-40, 1:250) and GAPDH (Abcam #ab9485 or Cell Signaling #2118 ...
• A critical period for prefrontal cortex PV interneuron myelination and maturation

  S. Hijazi, et al., bioRxiv - Neuroscience 2023

  Quote: ... and goat anti-MBP (1:300, Santa Cruz, C-16, sc-13 914).
• Increasing NPYergic transmission in the hippocampus rescues aging-related deficits of long-term potentiation in the mouse dentate gyrus

  Katharina Klinger, et al., bioRxiv - Neuroscience 2023

  Quote: ... The membranes were incubated with ms anti-Y1-R (1:500; Santa Cruz Biotechnology ...
• Regulating PCCA gene expression by modulation of pseudoexon splicing patterns to rescue enzyme activity in propionic acidemia

  Ulrika Simone Spangsberg Petersen, et al., bioRxiv - Molecular Biology 2023

  Quote: ... hnRNP A2/B1 (1:1000; sc-53531; Santa Cruz Biotechnology; Santa Cruz, CA), TDP-43 (1:1000 ...
• Regulating PCCA gene expression by modulation of pseudoexon splicing patterns to rescue enzyme activity in propionic acidemia

  Ulrika Simone Spangsberg Petersen, et al., bioRxiv - Molecular Biology 2023

  Quote: ... and hnRNP K (1:1000; sc-28380; Santa Cruz Biotechnology; Santa Cruz, CA).
• Regulating PCCA gene expression by modulation of pseudoexon splicing patterns to rescue enzyme activity in propionic acidemia

  Ulrika Simone Spangsberg Petersen, et al., bioRxiv - Molecular Biology 2023

  Quote: ... hnRNP A2/B1 (1:1000; sc-53531; Santa Cruz Biotechnology; Santa Cruz, CA), TDP-43 (1:1000 ...
• Regulating PCCA gene expression by modulation of pseudoexon splicing patterns to rescue enzyme activity in propionic acidemia

  Ulrika Simone Spangsberg Petersen, et al., bioRxiv - Molecular Biology 2023

  Quote: ... and hnRNP K (1:1000; sc-28380; Santa Cruz Biotechnology; Santa Cruz, CA).
• Beta-catenin mediates growth defects induced by centrosome loss in APC mutant colorectal cancer independently of p53

  Mohamed Bourmoum, et al., bioRxiv - Cancer Biology 2023

  Quote: ... β-catenin (Santa Cruz # sc-7963, WB: 0.2 μg/ml, IF: 1 μg/ml), anti-mouse Alexa Fluor 488 (ThermoFisher # A-21202 ...
• RAD52 and ERCC6L/PICH have a compensatory relationship for genome stability in mitosis

  Beth Osia, et al., bioRxiv - Cell Biology 2023

  Quote: ... Blots were probed using antibodies against RAD52 1:500 (Santa Cruz Biotechnology #sc365341), FLAG 1:1000 (Sigma #A8592) ...
• A spatially resolved EGFR signaling model predicts the length scale of GAB1-SHP2 complex persistence

  Paul J. Myers, et al., bioRxiv - Systems Biology 2023

  Quote: ... mouse SHP2 antibody (sc-7384, 1:50; Santa Cruz Biotechnology, Santa Cruz, CA) and rabbit GAB1 antibody (HPA049599 ...
• Sequential breakdown of the complex Cf-9 leaf mould resistance locus in tomato by Fulvia fulva

  Silvia de la Rosa, et al., bioRxiv - Microbiology 2023

  Quote: ... and chicken anti-mouse IgG-HRP (1:20,000) secondary antibody (Santa Cruz Biotechnology). Blotted membranes were incubated with SuperSignal West Pico chemiluminescent substrate (Thermo Fisher Scientific ...
• Cortical network and projection neuron types that articulate serial order in a skilled motor behavior

  Yi Li, et al., bioRxiv - Neuroscience 2023

  Quote: ... or mouse anti-Tle4 antibody (1:500, Cat#sc-365406, Santa Cruz Biotechnology). Briefly ...
• In Breast Cancer ZMIZ1 Co-Regulates E2F2 as Part of the Estrogen Receptor-Mediated Cell-Cycle Response

  Weiye Zhao, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Dual antibody recognition of ER using anti-ER antibody from Abcam (Ab3575) at 1:400 dilution and anti-ER antibody from Santa Cruz (SC8002) at 1:250 was used as a positive control ...
• Cleavage of the Jaw1 C-terminal region enhances its augmentative effect on the Ca²⁺ release via inositol 1,4,5-trisphosphate receptors

  Takuma Kozono, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-IP3R2 mouse antibody (1:1000) (#sc-398434; Santa Cruz Biotechnology, CA, USA), and anti-IP3R3 mouse antibody (1:1000 ...
• Caltubin regulates microtubule stability via Ca²⁺-dependent mechanisms favouring neurite regrowth

  Andrew Barszczyk, et al., bioRxiv - Cell Biology 2023

  Quote: ... Mouse anti-His6 (1:100; 1h for immunocytochemistry) (#sc-8036; Santa Cruz Biotechnology); goat anti-mouse-488 (1:200 ...
• The phosphodiesterase 2A regulates lymphatic endothelial development via cGMP-mediated control of Notch signaling

  Claudia Carlantoni, et al., bioRxiv - Developmental Biology 2023

  Quote: ... mouse anti-VE-cadherin (F8, Cat#: sc-9989, Santa Cruz Biotechnology, 1:100), goat anti-VE-cadherin (Cat# ...
• Fgf8 regulates first pharyngeal arch segmentation through pouch-cleft interactions

  Nathaniel Zbasnik, Jennifer L. Fish, bioRxiv - Developmental Biology 2023

  Quote: ... Primary antibodies used were: AP-2α (Santa Cruz sc-12726, 1:200 mouse), E-Cadherin (BD Transduction Laboratories 610181 ...
• Label-free and high-throughput removal of residual undifferentiated cells from iPSC-derived spinal-cord progenitor cells

  Tan Dai Nguyen, et al., bioRxiv - Bioengineering 2023

  Quote: ... The primary antibodies used were: OCT4 (1:500, sc-5279, Santa Cruz Biotechnology), SOX1 (1:500 ...
• The Lamin A/C Ig-fold undergoes cell density-dependent changes that alter epitope binding

  Melanie Wallace, et al., bioRxiv - Cell Biology 2023

  Quote: ... high affinity pan-RAR antagonist AGN-193109 (AGN, 1 µM, Santa Cruz Biotechnology), or vehicle control (0.15% EtOH ...
• Task-specific modulation of corticospinal neuron activity during skilled motor learning

  Najet Serradj, et al., bioRxiv - Neuroscience 2022

  Quote: ... Antibodies used for fluorescent immunohistochemistry were: Rabbit anti-PKCγ (1:100; Santa Cruz) and rabbit anti RFP (1:100 ...
• The G protein-coupled receptor TBXA2R activates ERMs to promote motility, invasion, and metastasis of triple-negative breast cancer cells

  Kévin Leguay, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and goat anti-mouse-IgG HRP (1:10000, Santa Cruz Biotechnology #sc-516102). Protein detection was finally performed using Amersham ECL Western Blotting detection reagent (GE Healthcare #CA95038-564L).
• Global substrate identification and high throughput in vitro dephosphorylation reactions uncover PP1 and PP2A-B55 specificity principles

  Jamin B. Hein, et al., bioRxiv - Cell Biology 2023

  Quote: The following antibodies where used: GAPDH-rabbit-1:1000 (Santa Cruz; sc-25778), H3S10p – rabbit-1:1000 (Milipore #06-570) ...
• Inhibiting Stromal Class I HDACs Curbs Pancreatic Cancer Progression

  Gaoyang Liang, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and HRP-conjugated secondary antibodies against rabbit (Santa Cruz, sc-2004, 1:5000) and mouse IgG (Santa Cruz ...
• The hypermorphic PLCγ2 S707Y variant dysregulates microglial cell function – insight into PLCγ2 activation in brain health and disease, and opportunities for therapeutic modulation

  Daniel Bull, et al., bioRxiv - Neuroscience 2023

  Quote: ... The primary antibodies: anti-PLCγ2 mouse antibody (sc-5283, 1:50, Santa Cruz) and anti-GAPDH mouse antibody (ab8245 ...
• Death Induced by Survival gene Elimination (DISE) is correlated with neurotoxicity in Alzheimer’s disease and aging

  Bidur Paudel, et al., bioRxiv - Neuroscience 2023

  Quote: ... HNF-3β RY7 (FOXA2) (mouse mAb, Santa Cruz # sc-101060, 1:100 IF), TUJ1 (mouse mAb ...
• A spatially resolved EGFR signaling model predicts the length scale of GAB1-SHP2 complex persistence

  Paul J. Myers, et al., bioRxiv - Systems Biology 2023

  Quote: ... mouse SHP2 antibody (sc-7384, 1:50; Santa Cruz Biotechnology, Santa Cruz, CA) and rabbit GAB1 antibody (HPA049599 ...
• CEBPA restricts alveolar type 2 cell plasticity during development and injury-repair

  Dalia Hassan, Jichao Chen, bioRxiv - Developmental Biology 2023

  Quote: ... mouse anti-homeodomain only protein (HOPX, 1:250, sc-398703 AF647, Santa Cruz). rat anti-KI67 (KI67 ...
• The Cardiac Calcium Handling Machinery is Remodeled in Friedreich’s Ataxia

  Roman Czornobil, et al., bioRxiv - Physiology 2023

  Quote: ... mouse monoclonal anti-SERCA2a (dilution 1:500; Santa Cruz Biotechnology; Catalog # sc-376235). The following secondary antibodies were used ...
• Nuclear NFκB Activity Balances Purine Metabolism in Cellular Senescence

  Sho Tabata, et al., bioRxiv - Systems Biology 2023

  Quote: ... HRP-linked anti-goat IgG (1:5000; Santa Cruz Biotechnology, Inc., sc-2020), and HRP-linked anti-rabbit IgG (1:5000 ...