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6801 - 6850 of 8862 citations for 6 1 4 dioxa 8 azaspiro 4.5 decan 8 yl 3 hydroxy 2 iminopyrimidin 4 amine since 2019

• Microglial synaptic pruning on axon initial segment of dentate granule cells: sexually dimorphic effects on fear response of adult rats subjected to early life stress

  Mario A. Zetter, et al., bioRxiv - Neuroscience 2020

  Quote: ... Animals were perfused 90 min after the behavioral experiment (Fig. 1) and IR performed using primary antibody rabbit anti Fos (Santa Cruz, SC-52, 100 μg/ ml, 1:1000, CA, USA) and a biotinylated secondary antibody (goat anti rabbit ...
• Inhibition of Metastatic Uveal Melanoma Cell Proliferation by the Histone Deacetylase 6 Inhibitor, Ricolinostat, is Linked to Altered Microphthalmia-associated Transcription Factor and Phospho-ERK Expression

  Husvinee Sundaramurthi, et al., bioRxiv - Cancer Biology 2021

  Quote: ... p-ERK (1:500; #sc-7383, Santa Cruz Biotechnology Inc.; Dallas, TX, USA), ERK (1:500 ...
• Inhibiting adult neurogenesis differentially affects spatial learning in females and males

  Timothy P O’Leary, et al., bioRxiv - Neuroscience 2021

  Quote: ... with mouse-anti DCX monoclonal antibody (Santa Cruz Biotechnology, sc-271390, 1:100) at 4°C for 3 days ...
• Tuba1a is uniquely important for axon guidance through midline commissural structures

  Georgia Buscaglia, et al., bioRxiv - Developmental Biology 2020

  Quote: ... Blots were incubated in HRP-conjugated Goat-anti-mouse (1:5,000; Santa Cruz) secondary antibody diluted in TBST containing 0.5% BSA with streptavidin-HRP (Bio-Rad ...
• Identification of Hsp90 inhibitors as potential drugs for the treatment of TSC1/TSC2 deficient cancer

  Evelyn M. Mrozek, et al., bioRxiv - Cancer Biology 2021

  Quote: ... at a dilution of 1:250 and TSC2 (sc-271314, Santa Cruz Biotechnology) at a dilution of 1:100 were used and incubated at 4 °C overnight ...
• TP53 promotes lineage commitment of human embryonic stem cells through ciliogenesis and sonic hedgehog signaling

  Sushama Sivakumar, et al., bioRxiv - Developmental Biology 2021

  Quote: ... The following primary antibodies were used: anti-p53 DO-1 (Santa Cruz Biotechnology) that recognizes epitopes in the region containing residues 11-25 ...
• NADPH and glutathione redox link TCA cycle activity to endoplasmic reticulum stress

  Erica R. Gansemer, et al., bioRxiv - Cell Biology 2019

  Quote: ... Primary antibodies were: CHOP (Santa Cruz sc-7351 or Proteintech 15204-1-AP), BiP (BD Biosciences 610978) ...
• Postnatal mechanical loading drives adaptation of tissues primarily through modulation of the non-collagenous matrix

  D. E. Zamboulis, et al., bioRxiv - Cell Biology 2020

  Quote: ... 1:250 for TNC (mouse IgG, sc-59884, Santa Cruz Biotechnology, Dallas, Texas), and 1:100 for ELN (mouse IgG ...
• Lysosomal nucleotide metabolism regulates ER proteostasis through mTOR signaling

  Keng Hou Mak, et al., bioRxiv - Cell Biology 2020

  Quote: ... The anti-beta-actin antibody is from Santa Cruz (sc-47778, 1:2,000). Protein detection was performed using chemiluminescent substrate (ECL™ Western Blotting Reagents ...
• A perinuclear microtubule-organizing center controls nuclear positioning and basement membrane secretion

  Yiming Zheng, et al., bioRxiv - Cell Biology 2019

  Quote: ... rabbit anti-TPI (1:10,000 for WB, Cat#sc-30145, Santa Cruz Biotechnology), rabbit anti-Msps (1:500 for IF ...
• RhoA effectors LOK/SLK activate ERM proteins to locally inhibit RhoA and define apical morphology

  Riasat Zaman, et al., bioRxiv - Cell Biology 2020

  Quote: ... Mouse anti-GFP used at 1:100 (immunofluorescence) was obtained from Santa Cruz Biotechnology ...
• Identification of a new regulation pathway of EGFR and E-cadherin dynamics

  Veronique Proux-Gillardeaux, et al., bioRxiv - Cell Biology 2020

  Quote: ... Ubiquitin was revealed with an antibody from Santa Cruz (sc8017, dilution 1/1000).
• DNAJB chaperones inhibit aggregation of destabilised proteins via a C-terminal region distinct from that used to prevent amyloid formation

  Shannon McMahon, et al., bioRxiv - Cell Biology 2020

  Quote: ... mouse anti-ubiquitin (1:1000; sc-8017, Santa Cruz Biotechnology, Dallas, TX, USA) or mouse anti-V5 (1:5000 ...
• Early enforcement of cell identity by a functional component of the terminally differentiated state

  Zahra Bahrami-Nejad, et al., bioRxiv - Cell Biology 2020

  Quote: ... Proteins were detected with anti-PPARG (1:1000, Santa Cruz Biotechnology, sc-7273), anti-FABP4 (1:1000 R&D Systems ...
• Single cell transcriptomic analyses reveal the impact of bHLH factors ATOH7 and Neurog2 on human retinal organoid development

  Xiangmei Zhang, et al., bioRxiv - Developmental Biology 2020

  Quote: ... goat anti-CHX10/VSX2 (N-18) (1:50; Santa Cruz Biotechnology, sc-21690); goat anti-BRN3a (1:100 ...
• Transcriptional evaluation of the ductus arteriosus at the single-cell level uncovers a requirement for vimentin for complete closure

  Jocelynda Salvador, et al., bioRxiv - Developmental Biology 2021

  Quote: ... anti-VE-cadherin goat polyclonal (discontinued- Santa Cruz Biotechnology #sc-6458, 1:200), anti-ERG (ABCAM #ab92513 ...
• BAF facilitates interphase nuclear membrane repair through recruitment of nuclear transmembrane proteins

  Alexandra M. Young, et al., bioRxiv - Cell Biology 2020

  Quote: Mouse anti–Lamin B1 (1:100; clone C12; sc-365214; Santa Cruz Biotechnology)
• BAF facilitates interphase nuclear membrane repair through recruitment of nuclear transmembrane proteins

  Alexandra M. Young, et al., bioRxiv - Cell Biology 2020

  Quote: Mouse anti–Lamin B1 (1:1,000; clone C12; sc-365214; Santa Cruz Biotechnology)
• Shigella sonnei O-antigen inhibits internalisation, vacuole escape and inflammasome activation

  Jayne L Watson, et al., bioRxiv - Microbiology 2019

  Quote: ... were used at 1:1000 dilution and mouse anti-hGSDMD (Santa Cruz Biotechnology) was used at 1:500.
• The p53-p21 axis plays a central role in lymphatic homeostasis and disease

  Rohan Mylavarapu, et al., bioRxiv - Developmental Biology 2021

  Quote: ... and mouse monoclonal p21 (1:100, sc-6246, Santa Cruz Biotechnology, California, USA) antibodies ...
• Loss of Corneal Raver2 Expression in Aniridia Associated Keratopathy

  Subrata K. Das, et al., bioRxiv - Developmental Biology 2020

  Quote: ... Immunolocalization was performed with Raver2 polyclonal antibody (1:50; Santa Cruz, sc-165338), or Raver1 polyclonal antibody (1:50 ...
• Palmitic acid induces inflammation in placental trophoblasts and impairs their migration toward smooth muscle cells through plasminogen activator inhibitor-1

  Amanda M. Rampersaud, et al., bioRxiv - Developmental Biology 2020

  Quote: ... or human leukocyte antigen-G (HLAG; sc-21799, 1:50, Santa Cruz Biotechnology). The following day ...
• Sensitization of Chrysosplenetin against Artemisinin Resistant Plasmodium berghei K173 via Blocking Host ABC Transporters Potentially Mediated by NF-κB p52 or PXR/CAR Signaling Pathway

  Xuesong Zhao, et al., bioRxiv - Molecular Biology 2022

  Quote: ... and mouse monoclonal antibody against β-actin (1:150; sc-47778, Santa Cruz). Antibodies were purchased from Abcam (Cambridge ...
• A PCNA-K164R mutation impinges on origin activation and mitotic DNA synthesis

  Wendy Leung, et al., bioRxiv - Molecular Biology 2022

  Quote: ... and mouse anti-Cyclin-A (Santa Cruz; sc-271682 clone B8; 1:200) primary antibodies overnight at 4 °C ...
• Signaling from the RNA sensor RIG-I is regulated by ufmylation

  Daltry L. Snider, et al., bioRxiv - Immunology 2022

  Quote: ... and anti-Myc (M-Santa Cruz or R-Cell Signaling Technology, 1:1000).
• Modular and Distinct Plexin-A4/FARP2/Rac1 Signaling Controls Dendrite Morphogenesis

  Victor Danelon, et al., bioRxiv - Neuroscience 2022

  Quote: ... and monoclonal mouse anti-HA (1:500, Santa Cruz Biotechnology, F7 sc-7392). Secondary fluorescently conjugated antibodies were AlexaFluor-488 donkey anti-mouse IgG (1:500 ...
• m⁶A demethylase ALKBH5 promotes tumor cell proliferation by destabilizing IGF2BPs target genes and worsens the prognosis of patients with non-small cell lung cancer

  Kazuo Tsuchiya, et al., bioRxiv - Cancer Biology 2022

  Quote: ... p53 (1:200 dilution, Sc-126; SANTA CRUZ BIO TECHNOLOGY, Dallas, TX, USA), and GAPDH (1:1000 dilution ...
• Emerin self-assembly and nucleoskeletal coupling regulate nuclear envelope mechanics against stress

  Anthony Fernandez, et al., bioRxiv - Cell Biology 2022

  Quote: ... and mouse anti-lamin A/C (1:1000, sc-7292, Santa Cruz Biotechnology) antibodies ...
• Neuronal hemoglobin induces loss of dopaminergic neurons in mouse Substantia nigra, cognitive deficits and cleavage of endogenous α-synuclein

  Santulli Chiara, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-α-syn (C-20) 1:200 (Santa Cruz Biotechnology, sc-7011-R), anti-α-syn (SYN-1 ...
• The Role of Rif1 in telomere length regulation is separable from its role in origin firing

  Calla B. Shubin, Carol W. Greider, bioRxiv - Molecular Biology 2020

  Quote: ... The αMyc antibody was used at 1:3000 (Santa Cruz 9E10 c-myc). αFLAG was used at 1:1000 (Sigma Aldrich M2 Flag F1804) ...
• GATA-1-dependent histone H3K27ac mediates erythroid cell-specific interaction between CTCF sites

  Yea Woon Kim, Yujin Kang, Jin Kang, AeRi Kim, bioRxiv - Molecular Biology 2020

  Quote: ... Antibodies used in ChIP experiment are GATA-1 (sc-1233) from Santa Cruz Biotechnology ...
• Substrate-induced clustering activates Trim-Away of pathogens and proteins

  Jingwei Zeng, et al., bioRxiv - Molecular Biology 2020

  Quote: ... Antibody incubations were mouse anti-ubiquitin (P4D1; Santa Cruz Biotehnology sc8017HRp; 1:1000), rabbit anti-Ube2N (Bio-Rad ...
• The chromatin remodeler Ino80 mediates alternative RNAPII pausing site determination

  Youngseo Cheon, et al., bioRxiv - Molecular Biology 2021

  Quote: ... and anti-β-actin (Santa Cruz sc-47778 HRP; used at 1:5000). The AID-tagged Ino80 cells were a gift from the Friedman lab as previously described (29) ...
• In vivo discovery of RNA proximal proteins in human cells via proximity-dependent biotinylation

  Xianzhi Lin, et al., bioRxiv - Molecular Biology 2020

  Quote: ... membranes were incubated with anti-FLAG (Santa Cruz, Cat.# sc-166384, 1:1,000), anti-HA (Santa Cruz ...
• TENT4A non-canonical poly(A) polymerase regulates DNA-damage tolerance via multiple pathways which are mutated in endometrial cancer

  Umakanta Swain, et al., bioRxiv - Molecular Biology 2020

  Quote: ... rabbit anti-TRF4 (H-172) (TENT4A) (Santa Cruz, sc-98490, dilution 1:500); anti-MBP monoclonal antibody ...
• Structural and functional characterization of the Spo11 core complex

  Corentin Claeys Bouuaert, et al., bioRxiv - Molecular Biology 2020

  Quote: ... Antibodies for western blotting were goat polyclonal anti-LexA (1:2000, Santa Cruz), rat polyclonal anti-α-tubulin (1:5000 ...
• Asthma-associated variants induce IL33 differential expression through a novel regulatory region

  Ivy Aneas, et al., bioRxiv - Genomics 2020

  Quote: ... Lysates were incubated overnight with 5ug of Oct-1 (Santa Cruz, sc-232x) or an IgG control (Santa Cruz ...
• Let-7 miRNAs control auditory sensory progenitor behavior in the vertebrate inner ear

  Lale Evsen, Shuran Zhang, Angelika Doetzlhofer, bioRxiv - Developmental Biology 2019

  Quote: ... and mouse α-β-actin HRP 1:400 (Santa Cruz, no.sc-47778 HRP) used as loading control ...
• Egalitarian binding partners, Dynein Light Chain and Bicaudal-D, act sequentially to link mRNA to the Dynein motor

  Chandler H. Goldman, et al., bioRxiv - Cell Biology 2019

  Quote: ... The following antibodies were used for immunoprecipitation: GST (Santa Cruz Biotechnology, 1:15) and mouse anti-BicD (Developmental Studies Hybridoma Bank ...
• Deletion of Sphingosine 1-Phosphate Receptor 1 in cardiomyocytes during development leads to abnormal ventricular conduction and fibrosis

  Ryan Jorgensen, et al., bioRxiv - Physiology 2020

  Quote: ... or Donkey anti-goat IgG-HRP (1:1000, Santa Cruz Biotechnology sc-2020). Signals were detected using SuperSignal West Pico PLUS Chemiluminescent Substrate (Thermo Scientific #34577) ...
• Inhibition of IL-1β secretion and mitochondria respiration by arsenite which acts on myocardial ischemia-reperfusion injury

  Min Li, et al., bioRxiv - Pharmacology and Toxicology 2019

  Quote: ... GADD153 (sc-7351) and Heme Oxygenase 1 (sc-136960) were from Santa Cruz biotechnology.
• Attenuated Dopamine Receptor Signaling in Nucleus Accumbens Core in a Rat Model of Chemically-Induced Neuropathy

  D.E. Selley, et al., bioRxiv - Pharmacology and Toxicology 2019

  Quote: ... then incubated with mouse monoclonal anti-D2R (1:250; Santa Cruz SC-5303) in TBS-T overnight at 4C to detect long and short forms of D2R at 51 and 48kDa ...
• Sugar-phosphate metabolism regulates stationary phase entry and stalk elongation in Caulobacter crescentus

  Kevin D. de Young, et al., bioRxiv - Microbiology 2019

  Quote: ... and probed using the following antibodies: FLAG (1:500, sc-166355, Santa Cruz) and DivK (1:1000 ...
• Inflammation Drives Alternative First Exon usage to Regulate Immune Genes including a Novel Iron Regulated Isoform of Aim2

  Elektra K. Robinson, et al., bioRxiv - Immunology 2020

  Quote: ... and horseradish peroxidase-conjugated b-actin monoclonal antibody (1:5,000, Santa Cruz Biotechnology) were used as a loading control ...
• Cigarette Smoke Exposure Impairs β-Cell Function Through Activation of Oxidative Stress and Ceramide Accumulation

  Xin Tong, et al., bioRxiv - Molecular Biology 2019

  Quote: ... anti-Cyclin D2 rabbit antibody (1:1000, Santa Cruz Biotechnology, Santa Cruz, CA), anti-Actin mouse antibody (1:10000 ...
• Cigarette Smoke Exposure Impairs β-Cell Function Through Activation of Oxidative Stress and Ceramide Accumulation

  Xin Tong, et al., bioRxiv - Molecular Biology 2019

  Quote: ... anti-Cyclin D2 rabbit antibody (1:1000, Santa Cruz Biotechnology, Santa Cruz, CA), anti-Actin mouse antibody (1:10000 ...
• Parkin-mediated ubiquitination contributes to the constitutive turnover of mitochondrial fission factor (Mff)

  Laura Lee, et al., bioRxiv - Cell Biology 2019

  Quote: ... Primary antibodies used were: Parkin (mouse monoclonal, 1:1000, Santa Cruz sc-32282), Mff (mouse monoclonal ...
• Lipopolysaccharide (LPS) induces increased epidermal green autofluorescence of mouse

  Yujia Li, Mingchao Zhang, Yue Tao, Weihai Ying, bioRxiv - Biophysics 2019

  Quote: ... or actin (1:1000, sc-58673, Santa Cruz Biotechnology, Inc., Dallas, TX, USA) with 0.05% BSA overnight at 4°C ...
• Depletion of Ric-8B leads to reduced mTORC2 activity

  Maíra H. Nagai, et al., bioRxiv - Molecular Biology 2019

  Quote: ... cells were double stained with anti-BrdU (Santa Cruz sc-32323, 1:400) and anti-cleaved caspase-3 primary antibodies (Cell Signaling #9661 ...
• Proper chromosome alignment depends on BRCA2 phosphorylation by PLK1

  Åsa Ehlén, et al., bioRxiv - Cell Biology 2019

  Quote: ... goat anti-rabbit IgG-HRP (IB: 1:5000, Cat. #sc-2054, Santa Cruz), goat anti-mouse IgG-HRP (1:10 000 ...