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6701 - 6750 of 8862 citations for 6 1 4 dioxa 8 azaspiro 4.5 decan 8 yl 3 hydroxy 2 iminopyrimidin 4 amine since 2019

• Dysfunctional Mitochondria in Cardiac Fibers of a Williams-Beuren Syndrome Mouse Model

  Noura Abdalla, et al., bioRxiv - Molecular Biology 2023

  Quote: ... Specimens were incubated with primary antibody TOM20 (1:250, Santa Cruz Biotechnology) overnight at 4ºC ...
• Cytotoxic CNS-associated T cells drive axon degeneration by targeting perturbed myelinating oligodendrocytes in PLP1 mutant mice

  Tassnim Abdelwahab, et al., bioRxiv - Neuroscience 2023

  Quote: ... goat anti-Brn3a (1:100, catalog no. sc-31984; Santa Cruz Biotechnology); immune reactions were visualized using fluorescently labeled (1:500 ...
• Differential regulation of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) receptor tetramerization by auxiliary subunits

  Noele Certain, et al., bioRxiv - Neuroscience 2023

  Quote: ... HRP-conjugated anti-mouse IgG (Santa Cruz Biotechnologies, sc-2031, 1:1000) was used as a secondary antibody ...
• Icariin prevents depression-like behaviors in chronic unpredictable mild stress-induced rats through Bax/cytoplasm C/caspase-3 axis to alleviate neuronal apoptosis

  Xiao Wu, et al., bioRxiv - Molecular Biology 2023

  Quote: ... mouse anti-Bax (1:400, Santa Cruz Biotechnology, Santa Cruz, CA, USA), anti-β-actin ...
• Icariin prevents depression-like behaviors in chronic unpredictable mild stress-induced rats through Bax/cytoplasm C/caspase-3 axis to alleviate neuronal apoptosis

  Xiao Wu, et al., bioRxiv - Molecular Biology 2023

  Quote: ... mouse anti-Bax (1:400, Santa Cruz Biotechnology, Santa Cruz, CA, USA), anti-β-actin ...
• Riluzole suppresses growth and enhances response to endocrine therapy in ER+ breast cancer

  Ayodeji O. Olukoya, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and staining for PCNA (1:1000, #sc-56, SCBT, Santa Cruz, CA), cleaved caspase 3 (1:300 ...
• Paclitaxel- and vincristine-induced neurotoxicity and drug transport in sensory neurons

  Christina Mortensen, et al., bioRxiv - Pharmacology and Toxicology 2023

  Quote: ... iPSC-SNs were labeled with peripherin (1:200, SC-377093, Santa Cruz) and TRPV1 (1:100 ...
• Traumatic brain injury modifies adult hippocampal neural stem cell fate to promote neurogenesis at the cost of astrogliogenesis

  P Bielefeld, et al., bioRxiv - Neuroscience 2023

  Quote: ... using goat-anti DCX (1:800 dilution; Santa Cruz, cat# sc-8066) in combination with donkey anti-goat-biotin (1:500 dilution ...
• The FGF/FGFR system in the microglial neuroinflammation with Borrelia burgdorferi: intersectionality with other neurological conditions

  Geetha Parthasarathy, et al., bioRxiv - Immunology 2022

  Quote: ... anti-FGFR3 (sc-123) (1:50; all rabbit polyclonal, Santa Cruz biotechnology) anti-phosphoFGFR1 (Tyr 653,654 ...
• Genetically perturbed myelin as a risk factor for neuroinflammation-driven axon degeneration

  Janos Groh, et al., bioRxiv - Neuroscience 2023

  Quote: ... biotin-XX phalloidin (1:300, catalog no. sc-505886; Santa Cruz Biotechnology); Labeling was visualized using AF555 donkey anti-rabbit (1:300 ...
• Plasticity of the proteasome-targeting signal Fat10 enhances substrate degradation

  Hitendra Negi, et al., bioRxiv - Biochemistry 2023

  Quote: ... and Mouse anti-β-actin antibody (Santa Cruz, 1 in 5000 dilutions) and further probed with HRP conjugated anti-mouse secondary antibody at 1:10,000 dilutions ...
• Distinct stem-like cell populations facilitate functional regeneration of the Cladonema medusa tentacle

  Sosuke Fujita, et al., bioRxiv - Developmental Biology 2023

  Quote: ... and rabbit anti-PKC ζ C20 (1:100; Santa Cruz, sc-216). After primary antibody incubation ...
• Multi-omics analyses identify transcription factor interplay in corneal epithelial fate determination and disease

  Jos GA Smits, et al., bioRxiv - Developmental Biology 2023

  Quote: ... FOSL1 aka Fra-1 (C-12) (mouse, Santa Cruz Biotechnology, sc-28310); Anti-FOSL2 (rabbit ...
• Harnessing Escherichia coli’s Dark Genome to Produce Anti-Alzheimer Peptides

  Neeraj Verma, Siddharth Manvati, Pawan K. Dhar, bioRxiv - Synthetic Biology 2023

  Quote: ... was diluted at 1:1000 and the GAPDH antibody (Santa Cruz Biotechnology) at 1:10000 in 1% skim milk and incubation was carried out at 4°C overnight.
• Paneth cells disruption and intestinal dysbiosis contribute to the development of Hirschsprung-associated enterocolitis in a benzalkonium chloride-induced Hirschsprung’s disease rat model

  Iskandar Rahardjo Budianto, et al., bioRxiv - Pathology 2023

  Quote: ... and occludin (60 kDa, 1:1000, sc-133256; Santa Cruz, CA, USA). Membranes were washed three times in TBS-T for 15 min and incubated with horseradish peroxidase-conjugated goat anti-rabbit IgG secondary antibody (1:5000 ...
• Cholangiocytic differentiation drives cell proliferation in hepatoblastoma through Wnt-dependent FGF19 signaling

  Peng V. Wu, et al., bioRxiv - Cancer Biology 2023

  Quote: ... The following antibodies were used: HNF4α (rabbit, 1:50; Santa Cruz sc8987), CK19 (rabbit ...
• Genetic validation of PfFKBP35 as an antimalarial drug target

  Basil T. Thommen, et al., bioRxiv - Molecular Biology 2023

  Quote: ... and mAb mouse α-fibrillarin (1:100, Santa Cruz Biotechnology sc-166021) for 1 h in 3% BSA in PBS and washed 3 times in PBS ...
• Nuclear aging in polyglutamine-induced neurodegeneration

  Dina Pereira, et al., bioRxiv - Neuroscience 2023

  Quote: ... and goat anti-lamin B (1:100, sc-6216 Santa Cruz Biotechnology) ON at 4°C ...
• Nuclear aging in polyglutamine-induced neurodegeneration

  Dina Pereira, et al., bioRxiv - Neuroscience 2023

  Quote: ... goat polyclonal anti-lamin B (1:750; sc-6216 Santa Cruz Biotechnology); mouse monoclonal anti-ZMSPTE24 (1:500 ...
• The CB₁ receptor interacts with cereblon and drives cereblon deficiency-associated memory shortfalls

  Carlos Costas-Insua, et al., bioRxiv - Neuroscience 2023

  Quote: ... mouse monoclonal anti-Gαq/11 (1:20, Santa Cruz Biotechnology #sc-515689), rabbit polyclonal anti-Gαs (1:20 ...
• Phosphoprotein dynamics of interacting tumor and T cells by HySic

  Sofía Ibáñez-Molero, et al., bioRxiv - Cancer Biology 2023

  Quote: ... The following antibodies were used: IFNyR1 (1:1000, Santa Cruz, sc-28363), totalSTAT1 (1:1000 ...
• Regulating PCCA gene expression by modulation of pseudoexon splicing patterns to rescue enzyme activity in propionic acidemia

  Ulrika Simone Spangsberg Petersen, et al., bioRxiv - Molecular Biology 2023

  Quote: ... or PCCB (1:500; sc-393929; Santa Cruz Biotechnology; Santa Cruz, CA), and GAPDH (1:5000 ...
• Interaction of PINK1 with nucleotides and kinetin

  Zhong Yan Gan, et al., bioRxiv - Molecular Biology 2023

  Quote: ... rabbit anti-Tom20 FL-145 (1:1,000, Santa Cruz Biotechnology, sc-11415), mouse anti-Parkin Prk8 (1:1,000 ...
• Phosphorylation of a Cleaved Tau Proteoform at a Single Residue Inhibits Binding to the E3 Ubiquitin Ligase, CHIP

  Cory M. Nadel, et al., bioRxiv - Biochemistry 2023

  Quote: ... and then incubated with primary anti-tau (Santa Cruz Biotech, 1:2000) followed by HRP-conjugated secondary antibody (Anaspec ...
• Urothelium-specific expression of mutationally activated Pik3ca initiates early lesions of non-invasive bladder cancer

  Lauren Shuman, et al., bioRxiv - Cancer Biology 2023

  Quote: ... goat anti-Foxa1 (1:1000; sc-6553; Santa Cruz Biotechnology; Dallas, TX), rabbit anti-Pparγ (1:200 ...
• The apoptotic, inflammatory, and fibrinolytic actions of vasoinhibin are in a motif different from its antiangiogenic HGR motif

  Juan Pablo Robles, et al., bioRxiv - Cell Biology 2023

  Quote: ... and incubated with 1:200 anti-NF-κB p65 antibodies (Santa Cruz Biotechnology ...
• Competition between myosin II and β_H-Spectrin regulates cytoskeletal tension

  Consuelo Ibar, et al., bioRxiv - Cell Biology 2023

  Quote: ... and as a loading control rabbit anti-GAPDH (1:5000; Santa Cruz Biotechnology ...
• Excess PrP^C inhibits muscle cell differentiation via miRNA-enhanced liquid–liquid phase separation implicated in myopathy

  Jing Tao, et al., bioRxiv - Biochemistry 2023

  Quote: ... mouse anti-MyoG antibody F5D (Santa Cruz Biotechnology sc-12732, 1:500), mouse anti-β-actin (Beyotime AA128 ...
• Cancer-associated fibroblasts produce matrix-bound vesicles that influence endothelial cell function

  Alice Santi, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and GAPDH (1/1,000, sc-48167 Santa Cruz Biotechnology, Inc., Dallas, TX). The membrane was incubated with HRP-conjugated (1/2,500 New England Biolabs ...
• Cleavage of the pseudoprotease iRhom2 by the signal peptidase complex reveals an ER-to-nucleus signalling pathway

  Iqbal Dulloo, et al., bioRxiv - Cell Biology 2022

  Quote: For immunoblotting and co-immunoprecipitation: Actin (Santa Cruz, #sc-47778; 1:5000), FLAG-HRP (Sigma Aldrich ...
• Structural insights into ion conduction by novel cation channel, TMEM87A, in Golgi apparatus

  Ah-reum Han, et al., bioRxiv - Biophysics 2023

  Quote: ... and mouse anti-β-actin antibodies (1:2000, sc-69879, Santa Cruz) overnight at 4°C ...
• LiverZap: A chemoptogenetic tool for global and locally restricted hepatocyte ablation to study cellular behaviours in liver regeneration

  Elizabeth M. G. Ambrosio, et al., bioRxiv - Cell Biology 2023

  Quote: ... goat α-Hnf4a (1:100; Santa Cruz, cat# sc-6556, lot# B1605), mouse α-E-cadherin (1:500 ...
• Identification of a mitochondrial targeting sequence in cathepsin D and its localization in mitochondria

  Naoki Ikari, Hirofumi Arakawa, bioRxiv - Cell Biology 2023

  Quote: ... and anti-goat IgG-HRP (1:5000, sc-2020, Santa Cruz Biotechnology)
• Histone demethylase KDM2A is a selective vulnerability of cancers relying on alternative telomere maintenance

  Fei Li, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and donkey anti-goat HRP (1:1,000, sc-2056, Santa Cruz Biotechnology). Antibody signal was detected using the ECL Western Blotting Substrate (W1015 ...
• Cardiomyocyte-fibroblast interaction regulates ferroptosis and fibrosis after myocardial injury

  Mary E. Mohr, et al., bioRxiv - Cell Biology 2023

  Quote: ... Primary Antibodies used include: FTH1 (1:1000, Santa Cruz Biotechnology, sc-376594), FTL (1:1000 ...
• Recruitment of the SNX17-Retriever recycling pathway regulates synaptic function and plasticity

  Pilar Rivero-Ríos, et al., bioRxiv - Cell Biology 2023

  Quote: ... SNX17 mouse monoclonal antibody (mAb) (1:50, sc-166957, Santa Cruz Biotechnology), VPS35L rabbit pAb (1:200 ...
• Peripherally targeted analgesia via AAV-mediated sensory neuron-specific inhibition of multiple pronociceptive sodium channels in rat

  Seung Min Shin, et al., bioRxiv - Neuroscience 2023

  Quote: ... Primary antibodies: mouse GFP (1:500, Santa Cruz Biotechnology, SCB, CA. sc9996), rabbit GFP (1:500 ...
• Phencyclidine disrupts neural coordination and cognitive control by dysregulating translation

  Eun Hye Park, et al., bioRxiv - Neuroscience 2023

  Quote: Primary antibodies were phospho-mTOR (Santa Cruz Biotechnology, Cat.No.101738, 1:1000), mTOR (Pierce ...
• IRF7 impacts on prostate cancer cell survival in response to radiation

  Adam Pickard, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Slides were incubated in IRF7 antibody (1:100, sc-74472, Santa Cruz) overnight at 4°C at a concentration of 2ug/ml ...
• Neuro-Regenerative Behavior of Adipose-Derived Stem Cells in Aligned Collagen I Hydrogels

  Mackenzie Lewis, et al., bioRxiv - Bioengineering 2023

  Quote: ... anti-mouse Yes-associated Protein (1:500, Santa Cruz Biotechnology, sc-101199), anti-mouse Neurofilament (1:500 ...
• Single-cell phenomics reveals behavioural and mechanical heterogeneities underpinning collective migration during mouse anterior patterning

  Matthew Stower, et al., bioRxiv - Developmental Biology 2023

  Quote: Primary antibodies used were 1:100 goat anti-AMOT (Santa Cruz, 82491), 1:100 rabbit anti-CDX2 (Cell Signalling ...
• Lipid transfer proteins initiate nuclear phosphoinositide signaling

  Noah D. Carrillo, et al., bioRxiv - Cell Biology 2023

  Quote: Monoclonal antibodies against p53 (clone DO-1, #SC-126, Santa Cruz Biotechnology), p53 (clone 7F5 ...
• CHAF1A promotes the translesion DNA synthesis pathway in response to DNA replication stress

  Bing Wen, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse monoclonal anti-Pol η (sc-17770, Santa Cruz Biotechnology; 1:1000), horseradish peroxidase (HRP)- conjugated beta actin monoclonal antibody (HRP-60008 ...
• RhoB promotes Salmonella survival by regulating autophagy

  Marco Kirchenwitz, et al., bioRxiv - Cell Biology 2023

  Quote: ... RhoB (sc-8048, Clone 5, 1:1000 dilution, RRID: AB_628219, Santa Cruz), RhoC (3430 ...
• RhoB promotes Salmonella survival by regulating autophagy

  Marco Kirchenwitz, et al., bioRxiv - Cell Biology 2023

  Quote: ... RhoB (sc-180, Clone 119, 1:1000 dilution, RRID: AB_2179110, Santa Cruz), RhoB (sc-8048 ...
• The effect of estradiol during the early stages of osteoclast differentiation is associated with the accumulation of phosphorylated p53 in mitochondria and the inhibition of mitochondrial metabolism

  Adriana Marques-Carvalho, et al., bioRxiv - Cell Biology 2023

  Quote: ... p-p53 (1:500, sc-51690, Santa Cruz Biotechnology, Dallas, TX, USA), Bak (1:1000 ...
• Lysyl oxidase regulates epithelial differentiation and barrier integrity in eosinophilic esophagitis

  Masaru Sasaki, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-DSG1 (1:1000; sc-137164; Santa Cruz Biotechnology, Dallas, TX, USA), anti-BMP2 (1:1000 ...
• The effect of estradiol during the early stages of osteoclast differentiation is associated with the accumulation of phosphorylated p53 in mitochondria and the inhibition of mitochondrial metabolism

  Adriana Marques-Carvalho, et al., bioRxiv - Cell Biology 2023

  Quote: ... TOM 20 (1:1000, sc-11415, Santa Cruz Biotechnology, Dallas, TX, USA) and β-actin (1:5000 ...
• Lysyl oxidase regulates epithelial differentiation and barrier integrity in eosinophilic esophagitis

  Masaru Sasaki, et al., bioRxiv - Cell Biology 2023

  Quote: ... and anti-DSG1 monoclonal antibody (1:100; sc-137164; Santa Cruz Biotechnology) at 4°C overnight and then with Cy2 or Cy5-AffiniPure Donkey Anti-Mouse IgG (H+L ...
• HuR modulation with tanshinone mimics impairs LPS response in murine macrophages

  Isabelle Bonomo, et al., bioRxiv - Molecular Biology 2023

  Quote: ... using 1-15 μg/mL of anti-HuR antibody (Santa Cruz, 71290) and the same amount of mouse normal IgG isotype (negative control ...