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6251 - 6300 of 8862 citations for 6 1 4 dioxa 8 azaspiro 4.5 decan 8 yl 3 hydroxy 2 iminopyrimidin 4 amine since 2019

• KDM3A and KDM3B Maintain Naïve Pluripotency Through the Regulation of Alternative Splicing

  Caleb M. Dillingham, et al., bioRxiv - Cell Biology 2024

  Quote: ... Primary antibodies: anti-HA (Santa Cruz sc7392, 1:250, lot#G0622), anti-PRMT5 (EMD Millipore 07-405 ...
• Delayed localization of A-type lamins to the rupture sites in Hutchinson–Gilford progeria syndrome

  Yohei Kono, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-β-Actin (1:2,000; AC-15, sc-69879, Santa Cruz) and anti-GAPDH (1:5,000 ...
• Phasic locus coeruleus activity enhances trace fear conditioning by increasing dopamine release in the hippocampus

  Jacob H. Wilmot, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-c-Fos goat primary antibody (1:5000, SC52, Santa Cruz), anti-GFP chicken primary antibody (1:300 ...
• WRNIP1 prevents transcription-associated genomic instability

  Pasquale Valenzisi, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-RNA pol II (mouse-monoclonal, Santa Cruz Biotechnology; 1:200), recombinant anti-S9.6 (rabbit-monoclonal ...
• An Aurora kinase A-BOD1L1-PP2A B56 Axis promotes chromosome segregation fidelity

  Thomas J. Kucharski, et al., bioRxiv - Cell Biology 2024

  Quote: ... mouse anti-PP2AR1A (Santa Cruz SC-74580; IB at 1:500), mouse anti-PP2AC (Santa Cruz SC-166034 ...
• An Aurora kinase A-BOD1L1-PP2A B56 Axis promotes chromosome segregation fidelity

  Thomas J. Kucharski, et al., bioRxiv - Cell Biology 2024

  Quote: ... mouse anti-PP2AC (Santa Cruz SC-166034; IB at 1:500), rabbit anti-PP2A B56 Alpha (MyBioSource.com MBS8524809 ...
• TANGO2-related rhabdomyolysis symptoms are associated with abnormal autophagy functioning

  Hortense de Calbiac, et al., bioRxiv - Cell Biology 2023

  Quote: ... and anti-β-actin (sc-81178, Santa Cruz Biotechnology, 1:1000). Immunoblots were incubated with the corresponding secondary horseradish peroxidase (HRP ...
• Decreased fucosylation impacts epithelial integrity and increases risk for COPD

  Carter Swaby, et al., bioRxiv - Cell Biology 2023

  Quote: ... were diluted 1:100 and SPC (518029, Santa Cruz Biotechnology (SCBT)) and CLDN4:AlexFluor488 (376643 ...
• Systematic Dissection of Sequence Features Affecting the Binding Specificity of a Pioneer Factor Reveals Binding Synergy Between FOXA1 and AP-1

  Cheng Xu, et al., bioRxiv - Genetics 2023

  Quote: ... and FOSL1 (mouse monoclonal, Santa Cruz Biotechnology, sc-28310, 1:50). The following secondary antibodies and dilutions were used ...
• APC/C prevents non-canonical order of cyclin/CDK activity to maintain CDK4/6 inhibitor-induced arrest

  Brandon L Mouery, et al., bioRxiv - Cell Biology 2023

  Quote: ... Cyclin B1 (1:1000; mouse; sc-245; Santa Cruz Biotechnology; milk), Total CDK1 (1:10,000 ...
• Interaction between Solo and PDZ-RhoGEF is involved in actin cytoskeletal remodeling and response to substrate stiffness

  Aoi Kunitomi, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse anti-RhoA (sc-418, 26C4, Santa Cruz Biotechnology, 1:250), mouse anti-α tubulin (T5168 ...
• The mitochondrial deoxyguanosine kinase is required for female fertility in mice

  Yake Gao, et al., bioRxiv - Cell Biology 2023

  Quote: ... donkey anti-mouse Tom20 1:500 (sc-17764, Santa Cruz Biotechnologies). Secondary antibodies ...
• Small molecule correctors divert CFTR-F508del from ERAD by stabilizing sequential folding states

  Celeste Riepe, et al., bioRxiv - Cell Biology 2023

  Quote: ... RNF5 22B3 Mouse Monoclonal (Santa Cruz Biotechnology, sc-81716, 1:1000), RNF185 + RNF5 Rabbit Monoclonal (Abcam ...
• Myocardin-related transcription factors regulate morphogenetic events in vertebrate embryos by controlling F-actin organization and apical constriction

  Keiji Itoh, et al., bioRxiv - Developmental Biology 2023

  Quote: ... Cryo-sections were stained with anti-GFP (Santa Cruz, 1/200) and anti-β-Catenin (Sigma ...
• Structural Host-Virus Interactome Profiling of Intact Infected Cells

  Boris Bogdanow, et al., bioRxiv - Microbiology 2023

  Quote: ... anti-UL48 (mouse clone 1-21, Santa Cruz Biotechnology, sc-7545).
• Interconversion of tripartite and bipartite systems for site-specific O-sialylation of flagellin in Gram-negative and Gram-positive bacteria

  Jovelyn Unay, Nicolas Kint, Patrick Viollier, bioRxiv - Microbiology 2023

  Quote: ... OctA-Probe monoclonal antibody (at dilution 1:1000; Santa Cruz Biotechnology) or anti DYKDDDK tag monoclonal antibody (at dilution 1:1000 ...
• Host-derived oxidized phospholipids initiate effector-triggered immunity fostering lethality upon microbial encounter

  Marco Di Gioia, et al., bioRxiv - Immunology 2023

  Quote: ... mouse anti-CD68 (1:100, Santa Cruz Biotechnology, Cat# sc-20060) and rat anti-Ly6G/Ly6C (1:50 ...
• An “alert state” ribosome population acts as a master regulator of cytokine-mediated processes

  Anna Dopler, et al., bioRxiv - Immunology 2023

  Quote: ... HSP 90α/β (Santa Cruz Animal Health sc-13119, 1:1000), RPL28 (Abcam ab138125 ...
• Phosphorylation of pyruvate dehydrogenase marks the inhibition of in vivo neuronal activity

  Dong Yang, et al., bioRxiv - Neuroscience 2023

  Quote: ... mouse monoclonal anti-cFos (1:500, Santa Cruz Biotechnology #sc-271243), rabbit anti-Orexin (1:100 ...
• Functionally dissecting claustrum along anterior-posterior axis in anxiety and higher sensitivity to cocaine

  Ziheng Zhao, et al., bioRxiv - Neuroscience 2023

  Quote: ... and mouse anti-CaMKIIα (1: 100, RRID: AB_626789, Santa Cruz, USA), followed by the corresponding fluorophore-conjugated secondary antibodies for 1 h at room temperature ...
• The phospho-regulated amphiphysin/endophilin interaction is required for synaptic vesicle endocytosis

  Christiana Kontaxi, Michael A. Cousin, bioRxiv - Neuroscience 2023

  Quote: ... goat CHC (1:250: Santa Cruz Biotechnology, cat no. sc-6579), mouse α-AP2 (1:1000 ...
• APOE3 Christchurch modulates tau phosphorylation and β-catenin/Wnt/Cadherin signaling in induced pluripotent stem cell-derived cerebral organoids from Alzheimer’s cases

  RC Mazzarino, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti β-catenin (E-5) (1:50, sc-7963, Santa Cruz) and anti-Reelin (CR-50 ...
• Noncannonical functions of Ku may underlie essentiality in human cells

  Rachel D. Kelly, et al., bioRxiv - Molecular Biology 2022

  Quote: ... mouse anti-goat IgG-HRP (Santa Cruz Biotechnology Inc., 1:3000), goat anti-rabbit IgG (H+L)-HRP Conjugate (BioRad ...
• Traumatic brain injury modifies adult hippocampal neural stem cell fate to promote neurogenesis at the cost of astrogliogenesis

  P Bielefeld, et al., bioRxiv - Neuroscience 2023

  Quote: ... goat anti-DCX (1:500 dilution; Santa Cruz, cat# sc-8066) in combination with donkey anti-goat Alexa 488 (1:500 dilution ...
• Partial in vivo reprogramming enables injury-free intestinal regeneration via autonomous Ptgs1 induction

  Jumee Kim, et al., bioRxiv - Cell Biology 2023

  Quote: ... and mouse anti-a-tubulin (Santa cruz, sc-8035, 1:1000). Incubated membrane was washed three times with TBS-T ...
• An O-GlcNAc transferase pathogenic variant that affects pluripotent stem cell self-renewal

  Michaela Omelková, et al., bioRxiv - Molecular Biology 2023

  Quote: ... Pax6 (H-295, Santa Cruz, catalogue number sc-11357, 1:1000), Sox17 (Santa Cruz ...
• An O-GlcNAc transferase pathogenic variant that affects pluripotent stem cell self-renewal

  Michaela Omelková, et al., bioRxiv - Molecular Biology 2023

  Quote: ... and Brachyury (D10, Santa Cruz, catalogue number sc-166962, 1:1000)) were added in blocking buffer overnight ...
• Self-stabilization mechanism encoded by a bacterial toxin facilitates reproductive parasitism

  Toshiyuki Harumoto, bioRxiv - Microbiology 2023

  Quote: ... mouse anti-β-Actin C4 (1/5,000; Santa Cruz, sc-47778). The following peroxidase-conjugated secondary antibodies were used (1/10,000 ...
• Characterization of the Human Immunodeficiency Virus (HIV-1) Envelope Glycoprotein Conformational States on Infectious Virus Particles

  Hanh T. Nguyen, et al., bioRxiv - Microbiology 2022

  Quote: ... 1:10,000 rabbit anti-hsp70 (K-20) antibody (Santa Cruz Biotechnology). The HRP-conjugated secondary antibodies were 1:2,000 rabbit anti-goat (Invitrogen) ...
• MARCH5-dependent NLRP3 ubiquitination is an essential step for NEK7 docking on the mitochondria

  Yeon-Ji Park, et al., bioRxiv - Immunology 2023

  Quote: ... anti-c-Myc (9E10) (1:1,000, sc-40, Santa Cruz biotechnology) anti-Tubulin (1:10,000 ...
• ARID1A-deficient cells promote endometrial carcinoma progression and dissemination by reprograming tumor microenvironment

  Cristina Megino-Luque, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-FAP (1:200, Triton X-100; Santa Cruz, sc-100528); anti-COL1A (1:200 ...
• Global loss of cellular m⁶A RNA methylation following infection with different SARS-CoV-2 variants

  Roshan Vaid, et al., bioRxiv - Molecular Biology 2022

  Quote: ... or anti-XPO1 (Santa Cruz, sc-74454 at 1:300 dilution) antibodies ...
• Zika virus E protein alters blood-brain barrier by modulating brain microvascular endothelial cell and astrocyte functions

  Guneet Kaur, et al., bioRxiv - Neuroscience 2023

  Quote: ... and anti-Vimentin (1:2000, Santa Cruz, USA, Cat# sc-6260). Cells were washed three times with 1X PBS and incubated with suitable fluorophore tagged secondary antibodies (1 ...
• Zika virus E protein alters blood-brain barrier by modulating brain microvascular endothelial cell and astrocyte functions

  Guneet Kaur, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-Vimentin (1:10000, Santa Cruz Biotechnology, USA, Cat# sc-6260), and anti-β-actin (1:40000 ...
• The effect of estradiol during the early stages of osteoclast differentiation is associated with the accumulation of phosphorylated p53 in mitochondria and the inhibition of mitochondrial metabolism

  Adriana Marques-Carvalho, et al., bioRxiv - Cell Biology 2023

  Quote: ... Bak (1:1000, sc-518146, Santa Cruz Biotechnology, Dallas, TX, USA), Bax (1:1000 ...
• Pathogenic mutations of human phosphorylation sites affect protein-protein interactions

  Trendelina Rrustemi, et al., bioRxiv - Systems Biology 2023

  Quote: ... mouse monoclonal IgG anti-GATAD1 (sc-81092, 1:100, Santa Cruz), in blocking solution for 1 hour ...
• Chronic intermittent hypoxia induced-dysmetabolism is associated with hepatic oxidative stress, mitochondrial dysfunction and inflammation

  Joana L. Fernandes, et al., bioRxiv - Physiology 2023

  Quote: ... or mouse anti-goat (1:2000, Santa Cruz Biotechnology, Dallas, USA) for 1.5h at room temperature.
• Electrophysiology of human iPSC-derived vascular smooth muscle cells and cell autonomous consequences of Cantu Syndrome mutations

  Alex Hanson, et al., bioRxiv - Physiology 2023

  Quote: ... mouse anti-Smoothelin (1:100; sc-376902, AF647 conjugated; Santa Cruz), rabbit anti-MYH11 (1:100 ...
• CCT and Cullin1 regulate the TORC1 pathway to promote dendritic arborization in health and disease

  Erin N. Lottes, et al., bioRxiv - Neuroscience 2023

  Quote: ... mouse anti-acetylated α-tubulin (1:100 dilution, Santa Cruz Biotechnology), mouse anti-Futsch (1:100 dilution ...
• Anti-apoptotic and anti-inflammatory properties of grapefruit IntegroPectin on human microglial HMC3 cell line

  Miriana Scordino, et al., bioRxiv - Neuroscience 2023

  Quote: ... mouse p-NF-kB (1:500, sc-136548 Santa Cruz Biotechnology). The day after ...
• OSGN-1 is a conserved flavin-containing monooxygenase required to stabilize the intercellular bridge in late cytokinesis

  Eugénie Goupil, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse α-6xHis (clone H3, 1:1000, Santa Cruz, sc-8036). The following secondary antibodies were used ...
• Propofol Reverses Surgery-Induced Neuroinflammation and Cognitive Impairment in Aged Mice via α5-GABA_A Receptors

  Rajasekar Nagarajan, et al., bioRxiv - Neuroscience 2023

  Quote: ... Na+/K+ ATPase (1:200, Santa Cruz Biotechnology, Catalog # SC-514661) and β-actin (1:2000 ...
• Serotonergic Modulation of the BNST-CeA Circuit Promotes Sex Differences in Fear Learning

  Rebecca Ravenelle, et al., bioRxiv - Neuroscience 2023

  Quote: ... mouse anti-GAD65/67 (1:250, Santa Cruz Biotechnology, #sc-365180), and guinea pig anti-vGlut3 (1:250 ...
• DNAJB1-PRKACA fusion protein-regulated LINC00473 promotes tumor growth and alters mitochondrial fitness in fibrolamellar carcinoma

  Rosanna K. Ma, et al., bioRxiv - Cancer Biology 2023

  Quote: ... mouse IgG secondary antibody (1:2000, Santa Cruz Biotechnology, sc-525409), and rabbit IgG secondary antibody (1:2000 ...
• Evolution of chromosome arm aberrations in breast cancer through genetic network rewiring

  Elena Kuzmin, et al., bioRxiv - Genomics 2023

  Quote: ... Anti-GAPDH primary antibody (Santa Cruz Biotechnology #sc-25778; 1:1000) was used as described above ...
• Establishment of a novel non-integrated human pluripotent stem cell-based gastruloid model

  Gege Yuan, et al., bioRxiv - Developmental Biology 2023

  Quote: ... mouse anti-AP2α antibody (Santa Cruz Biotechnology, SC-12726; 1:100), rabbit anti-KRT7 antibody (Zsbio ...
• polo affects cell fate upon ionizing radiation in Drosophila hematopoietic progenitors by negatively regulating lok

  Tram Thi Ngoc Nguyen, et al., bioRxiv - Developmental Biology 2023

  Quote: ... mouse anti-GFP (1:100, Santa Cruz Biotechnology, Dallas, TX, USA), rabbit anti-Polo (1:100 ...
• Myosin 10 uses its MyTH4 and FERM domains differentially to support two aspects of spindle pole biology required for mitotic spindle bipolarity

  Yang-In Yim, et al., bioRxiv - Cell Biology 2023

  Quote: ... and mouse anti-Tpx2 (Santa Cruz Biotechnology, sc-53775, 1:200), rat-anti-CD29 (BD Pharmingen ...
• Penile cavernous sinusoids are Prox1-positive hybrid vessels

  Sarah Schnabellehner, et al., bioRxiv - Cell Biology 2023

  Quote: ... rat anti-mouse EMCN (Santa Cruz Biotechnology, sc-65495; 1:200), rat anti-mouse PLVAP (BD Biosciences ...
• Development of an optimized, non-stem cell line for intranasal delivery of therapeutic cargo to the central nervous system

  Ali El-Ayoubi, et al., bioRxiv - Molecular Biology 2023

  Quote: ... Immunofluorescence was performed using the YB-1 antibody from Santa Cruz (#R0409 ...