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5351 - 5400 of 8510 citations for 6 Chloro 2 3 diphenylimidazo 1 2 b pyridazine since 2019

• Sex hormones underlying 17a-Estradiol effects on neuroinflammation

  Lucas K. Debarba, et al., bioRxiv - Neuroscience 2020

  Quote: ... For rabbit anti ER alpha (1:1000; Santa Cruz Biotechnology, CA) and rabbit anti pS6 (1:100 Cell signaling ...
• The histone modification reader ZCWPW1 links histone methylation to PRDM9-induced double strand break repair

  Tao Huang, et al., bioRxiv - Developmental Biology 2020

  Quote: ... rabbit anti-DMC1 (1:100 dilution; Santa Cruz Biotechnology #sc-22768), mouse anti-γH2AX (1:300 dilution ...
• LRRK2 causes centrosomal deficits via phosphorylated Rab10 and RILPL1 at centriolar subdistal appendages

  Antonio Jesús Lara Ordóñez, et al., bioRxiv - Neuroscience 2021

  Quote: ... and mouse monoclonal anti-GAPDH (Santa Cruz, sc-32233, 1:2000). Sheep polyclonal antibodies against Rab12 ...
• Tumour Suppressor Parafibromin/Hyrax Governs Cell Polarity and Centrosome Assembly in Neural Stem Cells

  Qiannan Deng, et al., bioRxiv - Developmental Biology 2021

  Quote: ... rabbit anti-aPKCζ C20 (1:100; Santa Cruz Biotechnologies, Dallas, TX), guinea-pig anti-Numb (1:1000 ...
• Acquisition of cellular properties during alveolar formation requires differential activity and distribution of mitochondria

  Kuan Zhang, et al., bioRxiv - Developmental Biology 2021

  Quote: ... mouse anti-HOPX (1:100, Santa Cruz Biotechnology, Cat# sc-398703). The primary antibodies used for frozen sections were ...
• The laminin-keratin link shields the nucleus from mechanical deformation and signalling

  Zanetta Kechagia, et al., bioRxiv - Cell Biology 2022

  Quote: ... mouse anti-GAPDH (6C5) 1:3000 (Santa Cruz, Cat# sc-32233), mouse Anti-Nesprin3 antibody [Nsp3] 1:500 (Abcam ...
• GCNA is a histone binding protein required for spermatogonial stem cell maintenance

  Jonathan Ribeiro, Gerry P. Crossan, bioRxiv - Physiology 2022

  Quote: ... anti-PLZF (1:100, catalog no. sc-28319, Santa Cruz Biotechnology); anti-WT1 (1:1000 ...
• GCNA is a histone binding protein required for spermatogonial stem cell maintenance

  Jonathan Ribeiro, Gerry P. Crossan, bioRxiv - Physiology 2022

  Quote: ... anti-PLZF (1:300, catalog no. sc-22839, Santa Cruz Biotechnology), anti-γH2AX (1:200 ...
• Plant autophagosomes mature into amphisomes prior to their delivery to the central vacuole

  Jierui Zhao, et al., bioRxiv - Plant Biology 2022

  Quote: ... 1 μM concanamycin A (conA) (CAS 80890-47-7; Santa Cruz); 50 μM 2,4-dinitrophenol (DNP ...
• A PCNA-K164R mutation impinges on origin activation and mitotic DNA synthesis

  Wendy Leung, et al., bioRxiv - Molecular Biology 2022

  Quote: ... rabbit anti-p21 (Santa Cruz, sc-397 clone C19; 1:1000), rabbit anti-FANCD2 (Abcam ...
• Genetic instability from a single S-phase after whole genome duplication

  Simon Gemble, et al., bioRxiv - Cell Biology 2022

  Quote: ... mouse anti-H2B (1/1000; sc-515808 from Santa Cruz Biotechnology), mouse anti-ORC1 (1/100 ...
• Genetic instability from a single S-phase after whole genome duplication

  Simon Gemble, et al., bioRxiv - Cell Biology 2022

  Quote: ... mouse anti-ORC1 (1/100; sc-398734 from Santa Cruz Biotechnology), mouse anti-MCM2 (1/500 ...
• Genetic instability from a single S-phase after whole genome duplication

  Simon Gemble, et al., bioRxiv - Cell Biology 2022

  Quote: ... mouse anti-CDC6 (1/500; sc-9964 from Santa Cruz, RRID:AB_627236), rabbit anti-CDT1 (1/500 ...
• Absence of postsynaptic activity on developing neurons alters gene expression profiles without preventing the refinement of inputs

  Yumaine Chong, Ellis Cooper, bioRxiv - Neuroscience 2022

  Quote: ... goat anti-MAP-1A (1:360; Santa Cruz Biotechnology, Dallas, TX)] ...
• Emerin self-assembly and nucleoskeletal coupling regulate nuclear envelope mechanics against stress

  Anthony Fernandez, et al., bioRxiv - Cell Biology 2022

  Quote: ... mouse anti-histone H2A (1:1000, Santa Cruz Biotechnology, sc-515808) and mouse anti-GAPDH (1:1000 ...
• The endoplasmic reticulum membrane protein complex localizes to the mitochondrial - endoplasmic reticulum interface and its subunits modulate phospholipid biosynthesis in Trypanosoma brucei

  Advaitha Iyer, et al., bioRxiv - Biochemistry 2022

  Quote: ... mouse monoclonal anti-cMyc (9E10, Santa Cruz Biotechnology; dilution 1:200), mouse anti-HA (16B12 ...
• A neuron, microglia, and astrocyte triple coculture model to study Alzheimer disease

  Celia Luchena, et al., bioRxiv - Neuroscience 2021

  Quote: ... Arginase I (1:200, sc-166920, Santa Cruz Biotechnology, CA, USA), Iba1 (1:500 ...
• Long-term Pannexin 1 ablation promotes structural and functional modifications in hippocampal neurons through the regulation of actin cytoskeleton and Rho GTPases activity

  Carolina Flores-Muñoz, et al., bioRxiv - Neuroscience 2021

  Quote: ... and GAPDH (mouse anti-GAPDH, sc-47724, Santa Cruz; 1:1000). After primary antibody incubation and washing incubation with a secondary anti-mouse HRP antibody (1:5000) ...
• The Cdc14 phosphatase controls resolution of recombination intermediates and crossover formation during meiosis

  Paula Alonso-Ramos, et al., bioRxiv - Genetics 2021

  Quote: ... goat polyclonal anti-Cdc14 (yE-17; 1:1000; Santa Cruz Biotechnology), goat polyclonal anti-Cdc5 (1:1000 ...
• BARD1 links histone H2A Lysine-15 ubiquitination to initiation of BRCA1-dependent homologous recombination

  Jordan R. Becker, et al., bioRxiv - Molecular Biology 2020

  Quote: ... mouse anti-BRCA1 D-9 (1:400, sc-6954 Santa Cruz), rabbit anti-BARD1 (1:500 ...
• Nucleolar stress controls mutant Huntingtin toxicity and monitors Huntington’s disease progression

  Aynur Sönmez, et al., bioRxiv - Neuroscience 2021

  Quote: ... and anti-beta actin (sc-47778, Santa Cruz Biotechnology, 1:1000). The secondary antibody was anti-mouse HRP (horseradish peroxidase)-linked (NA931 ...
• SWI/SNF chromatin remodeler complex within the reward pathway is required for behavioral adaptations to stress

  Abdallah Zayed, et al., bioRxiv - Neuroscience 2021

  Quote: ... an anti-BRG1 (mouse monoclonal, 1:1000, Santa Cruz, sc-17796) and an anti-BRM (rabbit polyclonal 1:500 ...
• Curcumin promotes progression of AApoAII amyloidosis and peroxisome proliferation in mice by activating the PPARα signaling pathway

  Jian Dai, et al., bioRxiv - Molecular Biology 2020

  Quote: ... or ApoE antibody (1:500, Santa Cruz, San Francisco, CA, USA). Next ...
• In vivo discovery of RNA proximal proteins in human cells via proximity-dependent biotinylation

  Xianzhi Lin, et al., bioRxiv - Molecular Biology 2020

  Quote: ... or anti-β-actin (Santa Cruz, Cat.# sc-47778, 1:2,000) at 4°C overnight ...
• Replication protein A binds RNA and promotes R-loop formation

  Olga M. Mazina, et al., bioRxiv - Molecular Biology 2020

  Quote: ... Then 40 µl (Santa Cruz Biotech, 25% slurry in 1 × PBS) of protein A/G plus agarose beads were added and incubation continued for another 2 h ...
• Tendon Cell Deletion of IKKβ/NF-κB Drives Functionally Deficient Tendon Healing and Altered Cell Survival Signaling In Vivo

  Katherine T. Best, et al., bioRxiv - Molecular Biology 2020

  Quote: ... F4/80 (1:500, Cat#: sc-26643, Santa Cruz, Dallas, TX), S100a4 (1:2000 ...
• Single-cell analysis of skeletal muscle macrophages reveals age-associated functional subpopulations

  Linda K. Krasniewski, et al., bioRxiv - Cell Biology 2022

  Quote: ... Detection of CD11b (Santa Cruz, Cat# sc-1186, 1:50 dilution) required TSA staining ...
• Myosin 10 supports mitotic spindle bipolarity by promoting PCM integrity and supernumerary centrosome clustering

  Yang-In Yim, et al., bioRxiv - Cell Biology 2022

  Quote: ... and mouse anti-Tpx2 (Santa Cruz Biotechnology, sc-53775, 1:200). AlexaFluor-conjugated and HRP-conjugated secondary antibodies were purchased from Jackson ImmunoResearch Laboratories ...
• Mechanisms of A-type lamin targeting to nuclear ruptures are disrupted in LMNA- and BANF1-associated progerias

  Rhiannon M. Sears, Kyle J. Roux, bioRxiv - Cell Biology 2022

  Quote: ... Mouse monoclonal anti-tubulin (1:5000; sc-32293; Santa Cruz Biotechnology) was used as a loading control ...
• Hypercapnia limits β-catenin-mediated alveolar type 2 cell progenitor function by altering Wnt production from adjacent fibroblasts

  Laura A. Dada, et al., bioRxiv - Cell Biology 2022

  Quote: ... at 1:1000 and rabbit-anti-GAPDH (Santa Cruz #sc-25778) at 1:1000.
• Epac1 regulates cellular SUMOylation by promoting the formation of SUMO-activating nuclear condensates

  Wenli Yang, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-UBA2 (1:250; Santa Cruz Biotechnology, Inc. Cat. # SC-376305), anti-UBC9 (1:50 ...
• Asthma-associated variants induce IL33 differential expression through a novel regulatory region

  Ivy Aneas, et al., bioRxiv - Genomics 2020

  Quote: ... 2μg Oct-1 antibody (Santa Cruz Biotechnology, Dallas, TX, sc-232) was added and incubated for another 20 minutes ...
• Transposable elements and their KZFP controllers are drivers of transcriptional innovation in the developing human brain

  Christopher J. Playfoot, et al., bioRxiv - Genomics 2020

  Quote: ... and HRP-conjugated anti-rabbit (Santa Cruz sc-2004 1:5000) antibodies were used where appropriate and the blot was visualised using the Fusion SOLO S (Vilber).
• Leptin Resistance in the Ovary of Obese Mice Is Associated with Profound Changes in the Transcriptome of Cumulus Cells

  Karolina Wołodko, et al., bioRxiv - Physiology 2020

  Quote: ... RP against STAT3 (1:200, cat# sc-482, Santa Cruz Biotechnology), MM against phosphorylated Tyr 705 pSTAT3 (1:200 ...
• Leptin Resistance in the Ovary of Obese Mice Is Associated with Profound Changes in the Transcriptome of Cumulus Cells

  Karolina Wołodko, et al., bioRxiv - Physiology 2020

  Quote: ... RP against STAT5 (1:200, cat# sc-835, Santa Cruz Biotechnology), MM against phosphorylated Tyr 694/699 pSTAT5 (1:200 ...
• Leptin Resistance in the Ovary of Obese Mice Is Associated with Profound Changes in the Transcriptome of Cumulus Cells

  Karolina Wołodko, et al., bioRxiv - Physiology 2020

  Quote: ... GP against PTP1B (1:200, cat# sc-1718, Santa Cruz Biotechnology), MM against SOCS3 (1:500 ...
• Leptin Resistance in the Ovary of Obese Mice Is Associated with Profound Changes in the Transcriptome of Cumulus Cells

  Karolina Wołodko, et al., bioRxiv - Physiology 2020

  Quote: ... MM against SOCS3 (1:500, cat# sc-51699, Santa Cruz Biotechnology) in cell lysates ...
• Functional significance and therapeutic potential of miR-15a mimic in pancreatic ductal adenocarcinoma

  Shixiang Guo, et al., bioRxiv - Cancer Biology 2019

  Quote: ... anti-p27 (1:500) (Santa Cruz Biotech Inc., Santa Cruz, CA), anti-Cyclin A (1:500 ...
• Functional significance and therapeutic potential of miR-15a mimic in pancreatic ductal adenocarcinoma

  Shixiang Guo, et al., bioRxiv - Cancer Biology 2019

  Quote: ... anti-p27 (1:500) (Santa Cruz Biotech Inc., Santa Cruz, CA), anti-Cyclin A (1:500 ...
• The midbody interactome reveals new unexpected roles for PP1 phosphatases in cytokinesis

  Luisa Capalbo, et al., bioRxiv - Cell Biology 2019

  Quote: ... mouse monoclonal anti-PRC1 (clone C-1, Santa Cruz, sc-376983), rabbit monoclonal anti-phospho PRC1 pT481 (Abcam ...
• Oncoprotein GT198 is a direct target of taxol

  Zheqiong Yang, et al., bioRxiv - Pharmacology and Toxicology 2019

  Quote: ... and mouse anti-α-tubulin (1:150, Santa Cruz, sc-5286). Biotinylated taxol staining was detected by streptavidin-R-Phycoerythrin (PE ...
• Tissue of Origin Dictates GOT1 Dependence and Confers Synthetic Lethality to Radiotherapy

  Barbara S. Nelson, et al., bioRxiv - Cancer Biology 2019

  Quote: ... anti-ME1 at a 1:1,000 dilution (Santa Cruz, sc-100569), anti-MDH1 at a 1:10,000 dilution (Abcam ...
• Let-7 miRNAs control auditory sensory progenitor behavior in the vertebrate inner ear

  Lale Evsen, Shuran Zhang, Angelika Doetzlhofer, bioRxiv - Developmental Biology 2019

  Quote: ... goat anti-JAG1 1:400 (Santa Cruz Cat. No. sc-6011), and mouse α-β-actin HRP 1:400 (Santa Cruz ...
• Mesenchymal-Epithelial Transition Regulates Initiation of Pluripotency Exit before Gastrulation

  Sofiane Hamidi, et al., bioRxiv - Developmental Biology 2019

  Quote: ... aPKC clone C-20 (1:100; Santa Cruz Biotechnology #sc-216), GM130 clone 35 (1:100 ...
• Mesenchymal-Epithelial Transition Regulates Initiation of Pluripotency Exit before Gastrulation

  Sofiane Hamidi, et al., bioRxiv - Developmental Biology 2019

  Quote: ... aPKCς clone C-20 (1:400; Santa Cruz Biotechnology #sc-216), β1-Integrin clone P5D2 (1:100 ...
• KAT2-mediated acetylation switches the mode of PALB2 chromatin association to safeguard genome integrity

  Marjorie Fournier, et al., bioRxiv - Cell Biology 2020

  Quote: ... anti-GST (Santa Cruz Biotechnology sc-138, mouse, WB:1/1000), biotin-HRP conjugated (Sigma A0185 ...
• Transcriptional signatures of participant-derived neural progenitor cells and neurons implicate altered Wnt signaling in Phelan McDermid syndrome and autism

  Michael S. Breen, et al., bioRxiv - Neuroscience 2019

  Quote: ... NPCs were labelled with Sox2 (Santa Cruz SC-17320, 1:100) and Nestin (ThermoFisher MA1-110 ...
• It takes two vanilloid ligand bindings per channel to transduce painful capsaicin stimuli

  Ting-Yi Liu, et al., bioRxiv - Molecular Biology 2019

  Quote: ... at 1:5000 dilution or anti-GAPDH antibody (Santa Cruz Biotechnology) at 1:5000 dilution ...
• Open the LID: LXRα regulates ChREBPα transactivity in a target gene-specific manner through an agonist-modulated LBD-LID interaction

  Qiong Fan, et al., bioRxiv - Molecular Biology 2019

  Quote: ... RXRα (sc-553, Santa Cruz Biotechnology, Dallas, TX, USA; 1:1000), ChREBP (NB400-135 ...
• Krüppel-like factor 2- induced microRNAs: implications for treatment of pulmonary hypertension

  Hebah Sindi, et al., bioRxiv - Cell Biology 2019

  Quote: ... human/mouse p65 (1:1000, Santa Cruz Biotechnology, SC-372-G) and human/mouse pSer536-p65 (1:1000 ...