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701 - 750 of 1267 citations for 2 CHLOROMETHYL 6 METHOXY 1H BENZO D IMIDAZOLE since 2020

• Metformin-mediated mitochondrial protection post-cardiac arrest improves EEG activity and confers neuroprotection and survival benefit

  Muhammad Shoaib, et al., bioRxiv - Neuroscience 2021

  Quote: ... and Total AMPK β1/2 (1:1000; Cell Signaling Technology, Beverly, MA). Detection used anti-rabbit horseradish peroxidase–conjugated secondary antibody (1:2000 ...
• The RNA binding proteins ZFP36L1 and ZFP36L2 modulate transcriptional and post-transcriptional genome-wide effects of glucocorticoids

  Jennifer Rynne, et al., bioRxiv - Molecular Biology 2022

  Quote: ... Precleared lysates were immunoprecipitated with BRF1/2 antibody (#2119, Cell Signaling Technology), Glucocorticoid Receptor antibody (#3660 ...
• Microfluidic immuno-serology assay revealed a limited diversity of protection against COVID-19 in patients with altered immunity

  Dongjoo Kim, et al., bioRxiv - Bioengineering 2022

  Quote: ... FITC conjugated anti-mouse IgG antibody (2 μg/ml, Cell Signaling Technology) was loaded in the first microfluidic channel to differentiate the location of loaded samples in fluorescent image as well as recognize the presence of mouse derived antibodies on PLL slide ...
• Retinoid acid receptor β mechanically regulates the activity of pancreatic cancer cells

  Carlos Matellan, et al., bioRxiv - Bioengineering 2022

  Quote: ... or anti-MLC-2 antibodies (Cell Signaling Technology, 3672S, Rabbit, 1:100) and anti-PAN cytokeratin (Abcam ...
• Copper chelation inhibits TGF-β pathways and suppresses epithelial-mesenchymal transition in cancer

  E. M. Poursani, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Phospho-p44/42 MAPK (pERK1/2)(T202/Y204) (D13.14.4E, Cell Signaling Technology), p44/42 MAPK (ERK1/2 ...
• Breast cancer mutations HER2^V777L and PIK3CA^H1047R activate the p21-CDK4/6 –Cyclin D1 axis driving tumorigenesis and drug resistance

  Xiaoqing Cheng, et al., bioRxiv - Cancer Biology 2022

  Quote: ... phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (Cell signaling technology, #9101). Secondary antibodies used include anti-rabbit IgG (H+L ...
• Cryptochromes and UBP12/13 deubiquitinases antagonistically regulate DNA damage response in Arabidopsis

  Yuzhao Hu, et al., bioRxiv - Plant Biology 2023

  Quote: ... anti-phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (Cell Signaling Technology), anti-actin (MP Biomedicals ...
• Loss of hepatic phosphoenolpyruvate carboxykinase 1 dysregulates metabolic responses to acute exercise but enhances adaptations to exercise training in mice

  Ferrol I. Rome, et al., bioRxiv - Physiology 2022

  Quote: ... and 3-hydroxymethylglutaryl-CoA synthase 2 (HMGCS2; Cell Signaling Technology, 20940S; RRID:AB_2798853). All primary antibodies were used as a dilution of 1:1000 ...
• PDGFRα/β heterodimer activation negatively affects downstream ERK1/2 signaling and cellular proliferation

  Maria B. Campaña, et al., bioRxiv - Cell Biology 2023

  Quote: ... phospho-ERK1/2 (Thr202/Tyr204) (1:1000; 9101; Cell Signaling Technology, Inc.); ERK1/2 (1:1000 ...
• Association of microglia loss with hippocampal network impairments as a turning point in the amyloid pathology progression

  Giusy Pizzirusso, et al., bioRxiv - Neuroscience 2024

  Quote: ... 1:1000 anti-Synaptotagmin-2 polyclonal rabbit antibody (#60889, Cell Signaling Technology), 1:1000 anti-GABA-A Receptor beta 3 polyclonal rabbit antibody (#NB300-199 ...
• Mitochondrial Raf1 Regulates Glutamine Catabolism

  Ronald L. Shanderson, et al., bioRxiv - Cancer Biology 2024

  Quote: Primary antibodies used: p44/42 (ERK1/2)(L34F12)(4696S, Cell Signaling Technology), Phospho-p44/42 MAPK (ERK1/2)(Thr202/204)(9101S ...
• Mitochondrial Raf1 Regulates Glutamine Catabolism

  Ronald L. Shanderson, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Phospho-p44/42 MAPK (ERK1/2)(Thr202/204)(9101S, Cell Signaling Technology),c-Raf (D4B3J ...
• An atlas of epithelial cell states and plasticity in lung adenocarcinoma

  Guangchun Han, et al., bioRxiv - Cancer Biology 2024

  Quote: ... p44/42 MAPK (ERK1/2, rabbit, Cell Signaling Technology, 9102, 1:2000), or S6 (E.573.4 ...
• Bromodomain-containing Protein 4 Regulates Innate Inflammation in Airway Epithelial Cells via Modulation of Alternative Splicing

  Morgan Mann, et al., bioRxiv - Systems Biology 2023

  Quote: ... 2 μg α-RelA antibody (Cell Signaling, Danvers, MA, USA, Cat. # 8242) was added to each extract ...
• Culture conditions greatly impact the levels of vesicular and extravesicular Ago2 and RNA in extracellular vesicle preparations

  Lizandra Jimenez, et al., bioRxiv - Cancer Biology 2023

  Quote: Rabbit anti-Argonaute 2 (cat no. 2897) was purchased from Cell Signaling. Rat anti-Ago2 (cat no ...
• Unique vulnerability of RAC1-mutant melanoma to combined inhibition of CDK9 and immune checkpoints

  Alexa C. Cannon, et al., bioRxiv - Cancer Biology 2023

  Quote: ... PAK 1/2/3 1:1000 (Cell Signaling Technology Cat# 2604, RRID:AB_2160225), Myc-Tag 1:1000 (Cell Signaling Technology Cat# 2276 ...
• Angpt1 binding to Tie1 regulates the signaling required for lymphatic vessel development in zebrafish

  Nanami Morooka, et al., bioRxiv - Developmental Biology 2023

  Quote: ... rabbit anti-Phospho-p44/42 MAPK (Erk1/2) (1:500, Cell signaling), and mouse anti-RFP (1:500 ...
• Non-glycosylated IGF2 prohormones are more mitogenic than native IGF2

  Pavlo Potalitsyn, et al., bioRxiv - Biochemistry 2023

  Quote: ... and IGF-2 Receptor/CI-M6PR (D3V8C) antibody (Cell Signaling, cat.no.14364). Anti-actin (20-33 ...
• Role of spike in the pathogenic and antigenic behavior of SARS-CoV-2 BA.1 Omicron

  Da-Yuan Chen, et al., bioRxiv - Microbiology 2023

  Quote: ... An anti-SARS-CoV-2 S antibody (Cell Signaling technologies: clone E5S3V) that showed equivalent immunoreactivity against WT and Omicron spike was used to identify virus-infected cells ...
• Endosome dysfunction leads to gain-of-function TLR7 and human lupus

  Harshita Mishra, et al., bioRxiv - Immunology 2023

  Quote: ... anti-Phospho-p44/42 (ERK1/2) (1:1000, 197G2, 4377T, Cell Signaling), anti-p44/42 (ERK1/2 ...
• Macrophage migration is differentially regulated by distinct ECM components

  Matthew W. Stinson, et al., bioRxiv - Cell Biology 2023

  Quote: ... Phospho-Myosin Light Chain 2 antibody (for immunofluorescence) (Polyclonal, Cell Signaling, #3674); Goat anti-Rabbit IgG Rhodamine Red-X (RRX ...
• Retroelement decay by the exonuclease XRN1 is a viral mimicry dependency in cancer

  Amir Hosseini, et al., bioRxiv - Cell Biology 2023

  Quote: ... F(ab’)2 Fragment (Alexa Fluor 647 Conjugate (Cell Signaling Technology, 4410) for 1 hour at room temperature ...
• Zmiz1 is a novel regulator of lymphatic endothelial cell gene expression and function

  Rajan K C, et al., bioRxiv - Molecular Biology 2023

  Quote: ... p-p44/42 MAPK (pERK1/2) (Cell Signaling Technology, 9101S, 1:1,000) and β-actin (Cell Signaling Technology ...
• Identification of an osteopontin-derived peptide that binds neuropilin-1 and activates vascular cells

  Yihong Chen, et al., bioRxiv - Cell Biology 2023

  Quote: ... phosphor-p42/44 MAPK (p-ERK1/2, Cell Signaling Technology, Danvers, MA) and GAPDH (Cell Signaling Technology ...
• Alveolar differentiation drives resistance to KRAS inhibition in lung adenocarcinoma

  Zhuxuan Li, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Phospho-p44/42 MAPK (Erk1/2) (#4370, Cell Signaling Technology, 1:1000), ERK (#9102S ...
• Host-derived oxidized phospholipids initiate effector-triggered immunity fostering lethality upon microbial encounter

  Marco Di Gioia, et al., bioRxiv - Immunology 2023

  Quote: ... phospho-ERK1/2 (Thr202/Tyr204) (1:1000, Cell Signaling Technology, Cat# 9106), ERK1/2 (1:1000 ...
• Subfamily C7 Raf-like kinases MRK1, RAF26, and RAF39 regulate immune homeostasis and stomatal opening in Arabidopsis thaliana

  Márcia Gonçalves Dias, et al., bioRxiv - Plant Biology 2023

  Quote: ... 1:2,000 rabbit anti-p44/42 MAPK (Erk1/2) (Cell Signaling 9102S); 1:10,000 goat anti-rabbit-IgG (Sigma A0545) ...
• Diet-induced obesity results in endothelial cell desensitization to VEGF-A and permanent islet vascular dysfunction

  Yan Xiong, et al., bioRxiv - Physiology 2023

  Quote: ... Erk1/2 antibody (rabbit, 1:2000; all from Cell Signaling Technology, USA), and α-tubulin antibody (mouse,1:1000 ...
• Drug-Induced p53 Activation Promotes Acinar Cell Identity and Prevents Pancreatic Cancer Initiation

  Jennifer J Twardowski, et al., bioRxiv - Cancer Biology 2024

  Quote: ... rabbit monoclonal anti-p-ERK1/2 (Cell Signaling Technology 4370S, 1:100), rabbit polyclonal anti-p53 (Invitrogen PA5-88098 ...
• Urban wastewater contains a functional human antibody repertoire of mucosal origin

  Sean Stephenson, et al., bioRxiv - Immunology 2024

  Quote: ... SARS-CoV-2 Spike Protein Serological IgG ELISA Kit (Cell Signaling, #20154C), and SARS-CoV-2 Spike Protein Serological IgA ELISA Kit (Cell Signaling ...
• Viral Insulin/IGF-like Peptides Selectively Activate Host Insulin/IGF Signaling pathways during Grouper Iridovirus Infection

  Aurelien Chuard, et al., bioRxiv - Microbiology 2024

  Quote: ... Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) Antibody (Cell Signaling #9101); p44/42 MAPK (Erk1/2 ...
• Targeting oncogenic K-Ras mutants with a small-molecule degrader through Nedd4-1

  Taoling Zeng, et al., bioRxiv - Cancer Biology 2024

  Quote: ... and anti-MEK1/2 (9122) antibodies were purchased from Cell Signaling Technology; rabbit anti-K-Ras (BS6231 ...
• Gestational arsenite exposure alters maternal postpartum heart size and induces Ca²⁺ handling dysregulation in cardiomyocytes

  Nicole Taube, et al., bioRxiv - Pharmacology and Toxicology 2024

  Quote: ... p44/42 MAPK (ERK1/2) (1:1000, Rabbit mAb, Cell Signaling, 9102S), p-p44/42 MAPK (T202/Y204 ...
• Activating SRC/MAPK signaling via 5-HT1A receptor contributes to the effect of vilazodone on improving thrombocytopenia

  Ling Zhou, et al., bioRxiv - Pharmacology and Toxicology 2024

  Quote: ... ERK1/2 (4696S) were obtained from Cell Signaling Technology (Boston, MA, USA), against NFE2 (11089-1-AP) ...
• A combination of the geroprotectors trametinib and rapamycin is more effective than either drug alone

  Lisonia Gkioni, et al., bioRxiv - Physiology 2024

  Quote: ... and total ERK1/2 (1:1000, anti-rabbit, Cell Signaling Technology, 4695) in 5% fatty-acid free BSA in TBS-T at 4°C overnight ...
• Rigosertib Reverses Hypertrophic Cardiomyopathy in RAF1-Associated Noonan Syndrome

  Levi Legler, et al., bioRxiv - Molecular Biology 2024

  Quote: ... and anti-phospho-ERK 1/2 (Thr202/Tyr204) (#9101) (Cell Signaling Technology). Visualization of the primary antibody binding was performed using the Li-Cor anti-rabbit 680 IRDye system in conjunction with the Li-Cor Odyssey FC ...
• Cocaine, via ΔFosB, remodels gene expression and excitability in ventral hippocampus

  Andrew L. Eagle, et al., bioRxiv - Neuroscience 2024

  Quote: ... or 2 μg of rabbit polyclonal IgG isotype (3900S, Cell Signaling Technology). Antibody-bound chromatin fragments were isolated with protein G plus/protein A agarose beads (MilliporeSigma) ...
• Improved protein binder design using beta-pairing targeted RFdiffusion

  Isaac Sappington, et al., bioRxiv - Biochemistry 2024

  Quote: ... Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (Cell Signaling Technology, #9101) 1:10,000 dilution ...
• Dynamic and structural insights into allosteric regulation on MKP5 a dual-specificity phosphatase

  Erin Skeens, et al., bioRxiv - Biochemistry 2024

  Quote: ... and ERK1/2 using anti-phospho-p38 MAPK (Cell Signaling Cat# 9215), anti-phospho-JNK1/2 (Cell Signaling cat#4668 ...
• Contractile forces direct the chiral swirling of minimal cell collectives

  Ghina Badih, et al., bioRxiv - Cell Biology 2024

  Quote: Rabbit Anti-Phospho-Myosin Light Chain 2 (Ser19) Antibody (Cell Signaling 3671) was used at 1/100 and secondary Goat anti-Rabbit IgG Alexa Fluor 546 antibody (Invitrogen A11035 ...
• The assessment of therapeutic autophagy inhibition in NF1 mutated tumor cells

  Shadi Zahedi, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Phospho-p44/42 MAP kinase (pERK1/2) (#9101S) (Cell Signaling, Danvers, MA); p44/42 MAP kinase (Erk1/2 ...
• Uncovering the mechanistic basis of intracellular Raf inhibitor sensitivity reveals synergistic cotreatment strategies

  Ethan G. Stoddard, et al., bioRxiv - Cell Biology 2024

  Quote: ... or Phospho-MEK1/2 (Ser217/221) (41G9) Rabbit mAb (Cell Signaling Technology)/Purified Mouse Anti-MEK1 Clone 25/MEK1 (BD Biosciences ...
• Uncovering the mechanistic basis of intracellular Raf inhibitor sensitivity reveals synergistic cotreatment strategies

  Ethan G. Stoddard, et al., bioRxiv - Cell Biology 2024

  Quote: ... or Phospho-MEK1/2 (Ser217/221) (41G9) Rabbit mAb (Cell Signaling Technology)/Purified Mouse Anti-MEK1 Clone 25/MEK1 (BD Biosciences ...
• Uncovering the mechanistic basis of intracellular Raf inhibitor sensitivity reveals synergistic cotreatment strategies

  Ethan G. Stoddard, et al., bioRxiv - Cell Biology 2024

  Quote: ... or Phospho-MEK1/2 (Ser217/221) (41G9) Rabbit mAb (Cell Signaling Technology)/Purified Mouse Anti-MEK1 Clone 25/MEK1 (BD Biosciences).
• Uncovering the mechanistic basis of intracellular Raf inhibitor sensitivity reveals synergistic cotreatment strategies

  Ethan G. Stoddard, et al., bioRxiv - Cell Biology 2024

  Quote: ... or Phospho-MEK1/2 (Ser217/221) (41G9) Rabbit mAb (Cell Signaling Technology)/Purified Mouse Anti-MEK1 Clone 25/MEK1 (BD Biosciences).
• ACRC/GCNA is an essential protease for the repair of DNA-protein crosslinks during vertebrate development

  Cecile Otten, et al., bioRxiv - Molecular Biology 2023

  Quote: ... or 50 ng DPC-DNA (for 6 hpf embryo samples) was subjected to western blotting and immunostained with the anti-H3 antibody (Cell Signaling, #9715, 1:3000). Briefly ...
• Proliferative response of ERα-positive breast cancer cells to 10 μM enterolactone, and the associated alteration in the transcriptomic landscape

  Juana Hatwik, et al., bioRxiv - Genomics 2023

  Quote: ... The blots were washed with 1X TBST (6 washes of 5 min each) followed by incubation with HRP-conjugated anti-rabbit secondary antibody (Cat. No. 7074S, Cell Signaling Technology, MA, USA) for 1 h at room temperature ...
• Decryption of sequence, structure, and functional features of SINE repeat elements in SINEUP non-coding RNA–mediated post-transcriptional gene regulation

  Harshita Sharma, et al., bioRxiv - Molecular Biology 2023

  Quote: Cells were washed with D-PBS (-) (Wako, 045-29795) and lysed using 140 µL of 10× Cell Lysis buffer (Cell Signaling Technology, 9803S) with PMSF (Cell Signaling Technology ...
• Coordination of transcriptional and translational regulations in human epithelial cells infected by Listeria monocytogenes

  Vinko Besic, et al., bioRxiv - Molecular Biology 2020

  Quote: ... phospho-eIF2α (Ser51) clone D9G8 #3398) or mouse monoclonal antibodies (eIF2α clone D-3, Santa Cruz #sc-133132, β-Actin clone E4D9Z, Cell Signaling Technology #58169 ...
• Adipocyte lipolysis abrogates skin fibrosis in a Wnt/DPP4-dependent manner

  A. Jussila, et al., bioRxiv - Cell Biology 2021

  Quote: ... Blots were incubated in 5% milk and 3% BSA block respectively for 1 hour at room temperature followed by incubation with α-DPP4 (R&D: AF954) or α-phospho-HSL (Cell signaling: 4139) primary antibody overnight at 4°C followed by species appropriate secondary antibody ...