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851 - 900 of 1267 citations for 2 CHLOROMETHYL 6 METHOXY 1H BENZO D IMIDAZOLE since 2020

• Elimination Of Aberrantly Specified Cell Clones Is Independent Of Interfacial Myosin II Accumulation

  Olga Klipa, Fisun Hamaratoglu, bioRxiv - Developmental Biology 2021

  Quote: ... rabbit anti-phospho-Myosin light chain 2 (Ser19) (1:50, Cell Signaling Technology #3671), rabbit anti-Ap (1:1000 ...
• Single Serine on TSC2 Exerts Biased Control over mTORC1 Activation by ERK1/2 but Not Akt

  Brittany L. Dunkerly-Eyring, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-phospho-p44/42 MAPK (ERK1/2) (Thr202/Tyr204) (Cell Signaling Technology, 1:1000), and anti-p44/42 MAPK (ERK1/2 ...
• Perfluorononanoic acid impedes mouse oocyte maturation by inducing mitochondrial dysfunction and oxidative stress

  Xiaofei Jiao, Ning Liu, Yiding Xu, Huanyu Qiao, bioRxiv - Cell Biology 2021

  Quote: ... Anti-phospho-p44/42 MAPK (Erk1/2) antibody was purchased from Cell Signaling Technologies. Alexa Fluor 488-conjugated goat anti-mouse IgG (H + L ...
• Inverse Agonist Activity of Angiotensin II Receptor Blocker Is Crucial for Prevention of Aortic Aneurysm Formation in Marfan Syndrome

  Hiroki Yagi, et al., bioRxiv - Pharmacology and Toxicology 2022

  Quote: ... rabbit polyclonal anti-phosphorylated ERK1/2 antibody (Thr202/Tyr 204) (Cell Signaling Technology, #9101). The Vectastain ABC kit (Vector Laboratories ...
• Matrin3 regulates cell proliferation and spindle dynamics by regulating CDC14B alternative splicing

  Bruna R. Muys, et al., bioRxiv - Molecular Biology 2022

  Quote: ... 2 µg of anti-Matrin3 or normal rabbit IgG (Cell Signaling, Catalog no. 2729S) were coupled with the beads overnight ...
• P-TEFb promotes cell survival upon p53 activation by suppressing intrinsic apoptosis pathway

  Zhijia Wang, et al., bioRxiv - Biochemistry 2022

  Quote: ... We used 2 μg of anti-RNA polymerase II RPB1 NTD (Cell Signaling Technology), 1 μg of anti-RNA polymerase II CTD repeat YSPTSPS (phospho S2 ...
• P-TEFb promotes cell survival upon p53 activation by suppressing intrinsic apoptosis pathway

  Zhijia Wang, et al., bioRxiv - Biochemistry 2022

  Quote: ... anti-phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (Cell Signaling Technology, 1:4000); anti-p44/42 MAPK (Erk1/2 ...
• Calpain-mediated proteolysis of vimentin filaments is augmented in Giant Axonal Neuropathy (GAN) fibroblasts exposed to hypotonic stress

  Cassandra L. Phillips, et al., bioRxiv - Cell Biology 2022

  Quote: ... rabbit anti-Calpain 2 (Cell Signaling Technology, large subunit M-type, WB 1:1000), and rabbit anti-Calpain 2 (Cell Signaling Technology ...
• Metabotropic NMDA Receptor Signaling Contributes to Sex Differences in Synaptic Plasticity and Episodic Memory

  Aliza A. Le, et al., bioRxiv - Neuroscience 2024

  Quote: ... RRID:AB_310282) or rabbit anti-pERK1/2 (Thr202/Tyr204) (1:500; Cell Signaling 4377, AB_331775); Mouse anti-PSD95 (1:1000 ...
• A cellular assay to determine the fusion capacity of MFN2 variants linked to Charcot-Marie-Tooth type 2A

  Chloe Barsa, et al., bioRxiv - Cell Biology 2024

  Quote: ... and rabbit monoclonal anti-Mitofusin-2 (D1E9) (Cell Signaling, 11925, dilution of 1/100).
• Multiomic ALS signatures highlight sex differences and molecular subclusters and identify the MAPK pathway as therapeutic target

  Lucas Caldi Gomes, et al., bioRxiv - Neuroscience 2024

  Quote: ... rabbit anti p44/42 mitogen-activated protein kinase (anti-Erk1/2) (Cell Signaling Technology, Danvers ...
• Lipoxin A₄ yields an electrophilic 15-oxo metabolite that mediates FPR2 receptor-independent anti-inflammatory signaling

  Adolf Koudelka, et al., bioRxiv - Biochemistry 2024

  Quote: ... Membranes were washed in TBS-T and primary antibodies COX-2 (Cell Signaling: 12282T), FLAP (Invitrogen ...
• Phase diversity-based wavefront sensing for fluorescence microscopy

  Courtney Johnson, et al., bioRxiv - Bioengineering 2024

  Quote: ... and Rabbit anti Phospho-Myosin Light Chain 2 (Thr18/Ser19) (Cell Signaling Technology, 3674), both at 1:200 dilution in PBS containing 1% BSA ...
• Design of Cytotoxic T Cell Epitopes by Machine Learning of Human Degrons

  Nicholas L. Truex, et al., bioRxiv - Immunology 2023

  Quote: ... Primary and secondary antibodies for visualization of the bands include: Erk1/2 (Cell Signaling), goat anti-mouse IRdye680 (LI-COR Biosciences) ...
• Myc controls IL-15-driven expansion and translational machinery of NK cells

  Hanif J. Khameneh, et al., bioRxiv - Immunology 2022

  Quote: ... phospho-ERK1/2 (Thr202/Tyr204; D13.14.4E; XP Rabbit mAb #4370; Cell Signaling, 1:150).
• Unique vulnerability of RAC1-mutant melanoma to combined inhibition of CDK9 and immune checkpoints

  Alexa C. Cannon, et al., bioRxiv - Cancer Biology 2023

  Quote: ... phospho-ERK 1/2 Y202/204 1:2000 (Cell Signaling Technology Cat# 4370, RRID:AB_2315112), ERK 1:1000 (Cell Signaling Technology Cat# 4695 ...
• Cellular mechanisms of heterogeneity in NF2-mutant schwannoma

  Christine Chiasson-MacKenzie, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-phospho p44/42 (ERK1/2) rabbit mAb (1:1000; D13.14.4E, Cell Signaling Technology); anti-p44/42 (ERK1/2 ...
• In Vitro Validation of Computationally Predicted Oncogenic Driver Mutations in EGFR Tyrosine Kinase Domain

  Vidya P Warrier, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-phospho-ERK1/2 and the appropriate secondary antibodies were purchased from Cell Signaling or Santa Cruz Biotechnology ...
• The role of calcium, Akt and ERK signaling in cadmium-induced hair cell death

  Jennifer Galdieri, et al., bioRxiv - Neuroscience 2023

  Quote: ... and rabbit anti-phospho-p44/42 MAPK (ERK1/2) (Thr202/Tyr204) (Cell Signaling, 4370) diluted at 1:200.
• Infection-induced epilepsy is caused by increased expression of chondroitin sulfate proteoglycans in hippocampus and amygdala

  Dipan C. Patel, et al., bioRxiv - Neuroscience 2023

  Quote: ... and rabbit polyclonal anti-α-tubulin antibody (2 µg/ml; 2144, Cell Signaling Technology) overnight at 4 °C ...
• Tumor suppressor let-7 acts as a key regulator for maintaining pluripotency gene expression in Muse cells

  Gen Li, Shohei Wakao, Masaaki Kitada, Mari Dezawa, bioRxiv - Cell Biology 2023

  Quote: ... Phospho-p44/p42 MEK/ERK (ERK1/2; Thr202/Tyr 204) (1:1000, Cell Signaling), p44/p42 MEK/ERK (ERK1/2 ...
• Identification of SIRT4 as a novel paralog-specific interactor and candidate suppressor of C-RAF kinase in MAPK signaling

  Mehrnaz Mehrabipour, et al., bioRxiv - Biochemistry 2023

  Quote: ... anti-p-ERK(1/2) (1:1000; #4370, Cell Signaling, Frankfurt am Main, Germany); anti-KRAS (1:1000 ...
• PPARγ controls ESCRT-dependent fibroblast-like synoviocyte exosome biogenesis and Alleviates Chondrocyte Osteoarthritis Mediated by Exosomal ANXA1

  Shuangshuo Jia, et al., bioRxiv - Cell Biology 2023

  Quote: ... p44/42 MAPK (Erk1/2) (137F5) Rabbit mAb (4695, 1:30, Cell Signaling Technology), anti-Hrs (sc-271455 ...
• PPARγ controls ESCRT-dependent fibroblast-like synoviocyte exosome biogenesis and Alleviates Chondrocyte Osteoarthritis Mediated by Exosomal ANXA1

  Shuangshuo Jia, et al., bioRxiv - Cell Biology 2023

  Quote: ... p44/42 MAPK (Erk1/2) (137F5) Rabbit mAb (4695, 1:1000, Cell Signaling Technology), Phospho-p44/42 MAPK (Erk1/2 ...
• Engineering Regionally-Activated Drugs for Neuroscience

  Zhimin Huang, et al., bioRxiv - Bioengineering 2023

  Quote: ... (2) incubate with primary rabbit anti-c-Fos (1:2000, 2250S, Cell Signaling Technology) and chicken antityrosine hydroxylase (1:2000 ...
• Engineering Regionally-Activated Drugs for Neuroscience

  Zhimin Huang, et al., bioRxiv - Bioengineering 2023

  Quote: ... (2) incubate with primary rabbit anti-c-Fos (1:2000, 2250S, Cell Signaling Technology) antibody in PBS with 0.3% Triton-X for 2h at room temperature ...
• E-cadherin-dependent phosphorylation of EGFR governs a homeostatic feedback loop controlling intercellular junction viscosity and collective migration modes

  Chaoyu Fu, et al., bioRxiv - Cell Biology 2023

  Quote: ... Phospho-Myosin Light Chain 2 (Ser19) antibody (3671, Cell Signaling Technologies, diluted 1:50) according to the manufacturer’s instructions ...
• Oseltamivir (Tamiflu), a Commonly Prescribed Antiviral Drug, Mitigates Hearing Loss in Mice

  Emma Sailor-Longsworth, et al., bioRxiv - Neuroscience 2024

  Quote: ... or antibody anti-pERK1/2 (Thr202/Tyr204, 1:400 dilution, 9101, Cell Signaling Technology) and imaged with a confocal microscope (LSM 700 ...
• Therapeutic expression of RAS Degrader RRSP in Pancreatic Cancer via Nanocarrier-mediated mRNA delivery

  Taylor E. Escher, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Anti–Phospho-p44/42 MAPK (pERK1/2; Cell Signaling Technology, catalog no. 4377, RRID:AB_331775), anti-p44/42 MAPK (ERK1/2 ...
• Synthesis of ionizable lipopolymers using split-Ugi reaction for pulmonary delivery of various size RNAs and gene editing

  K. Yu. Vlasova, et al., bioRxiv - Bioengineering 2024

  Quote: ... cycle 2 Rabbit E-Cadherin (Cell Signaling, 24E10 #3195, dilution 1:200, 1 h), cycle 3 Rabbit CD31 (Abcam ...
• Netrin signaling mediates survival of dormant epithelial ovarian cancer cells

  Pirunthan Perampalam, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Phospho-p44/42 MAPK(Erk1/2) T202/Y204 (Cell Signaling Technology; rabbit antibody #4370), p38 MAPK (Cell Signaling Technology ...
• Dormancy-inducing 3D-engineered matrix uncovers mechanosensitive and drug protective FHL2-p21 signaling axis

  Sadra Bakhshandeh, et al., bioRxiv - Bioengineering 2024

  Quote: ... and anti-phospho-p44/42 MAPK (p-ERK1/2) (1:200, #9101S, Cell Signaling). The secondary antibodies are ...
• Vascular endothelial growth factor-D improves lung vascular integrity during acute lung injury

  Yifan Yuan, et al., bioRxiv - Molecular Biology 2024

  Quote: ... and Thr18/Ser19 Phospho-Myosin Light Chain 2 (#3674) from Cell Signaling Technology (Danvers); ICAM-1 (Santa Cruz Biotechnologies ...
• Positional information drives distinct traits in transcriptomically identified neuronal types

  Inbal Shainer, et al., bioRxiv - Neuroscience 2024

  Quote: ... fixed in 4% PFA and immunostained with Mouse anti-ERK1/2 (Cell Signaling Technology) and Chicken anti-GFP (Invitrogen) ...
• Mechanisms driving epigenetic and transcriptional responses of microglia in a neurodegenerative lysosomal storage disorder model

  Christopher D. Balak, et al., bioRxiv - Neuroscience 2024

  Quote: ... 2 μg each of two TFEB antibodies (Abcam ab2636, Cell Signaling CST 37785 (D2O7D), or 2 μg each of two TFE3 antibodies (Abcam ab93808 ...
• A spreading, multi-tissue wound signal initiates whole-body regeneration

  Catriona Breen, Mansi Srivastava, bioRxiv - Developmental Biology 2024

  Quote: ... Primary antibodies used are as follows: rabbit anti-pERK1/2 (Cell Signaling Technology 4370) 1:100 ...
• Transient proliferation by reversible YAP and mitogen-control of the cyclin D1/p27 ratio

  Katherine R. Ferrick, et al., bioRxiv - Cell Biology 2024

  Quote: ... rabbit phospho-MAPK1/2(Thr202/Tyr204)(1:400, Cell Signaling Technology Cat#4370, RRID:AB_2315112), mouse phospho-S6(235/236)(1:800 ...
• Rho-ROCK liberates sequestered claudin for rapid de novo tight junction formation

  Yuma Cho, et al., bioRxiv - Cell Biology 2024

  Quote: ... rabbit anti-phosoho-Myosin Light Chain 2 (Thr18/Thr19) mAb (95777; Cell Signaling Technology); rabbit anti-TROP2 mAb (ab214488 ...
• PCDHGC3 silencing promotes clear cell renal cell carcinoma metastasis via mTOR/HIF2α and lipid metabolism reprogramming

  Lucía Celada, et al., bioRxiv - Cancer Biology 2024

  Quote: ... rabbit anti-phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (#9101 Cell Signaling Technology) at 1:1,000 dilution ...
• Mutant RIT1 cooperates with YAP to drive an EMT-like lung cancer state

  Mary C. Rominger, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Phospho-p44/42 MAPK (Erk1/2) 1:1000 (Thr202/Tyr204) (Cell Signaling Technology, 4370), AKT 1:1000 (Cell Signaling Technology ...
• Loss of the predicted cell adhesion molecule MPZL3 promotes EMT and chemoresistance in ovarian cancer

  Ya-Yun Cheng, et al., bioRxiv - Cancer Biology 2024

  Quote: ... and incubated with blocking buffer containing 2% goat serum/PBS (Cell Signaling Technology, 5425) for 30 mins at room temperature ...
• Suppression of TGF-β/SMAD signaling by an inner nuclear membrane phosphatase complex

  Zhe Ji, et al., bioRxiv - Cell Biology 2024

  Quote: ... cells were incubated with 2 ng/mL TGF-β3 (Cell signaling #8425 and #10858) or 20 ng/mL BMP-4 (Peprotech 120-05 ...
• Uncovering the mechanistic basis of intracellular Raf inhibitor sensitivity reveals synergistic cotreatment strategies

  Ethan G. Stoddard, et al., bioRxiv - Cell Biology 2024

  Quote: p44/42 MAPK (Erk1/2) (3A7) Mouse mAb (Cell Signaling Technology, cat. no. 9107)
• Uncovering the mechanistic basis of intracellular Raf inhibitor sensitivity reveals synergistic cotreatment strategies

  Ethan G. Stoddard, et al., bioRxiv - Cell Biology 2024

  Quote: Phospho-MEK1/2 (Ser217/221) (41G9) Rabbit mAb (Cell Signaling Technology, cat. no. 9154) c-Raf (D4B3J ...
• Uncovering the mechanistic basis of intracellular Raf inhibitor sensitivity reveals synergistic cotreatment strategies

  Ethan G. Stoddard, et al., bioRxiv - Cell Biology 2024

  Quote: ... /Phospho-p44/42 MAPK (Erk1/2) D13.14.4E XP®Rabbit mAb (Cell Signaling Technology) or Phospho-MEK1/2 (Ser217/221 ...
• Uncovering the mechanistic basis of intracellular Raf inhibitor sensitivity reveals synergistic cotreatment strategies

  Ethan G. Stoddard, et al., bioRxiv - Cell Biology 2024

  Quote: ... /Phospho-p44/42 MAPK (Erk1/2) D13.14.4E XP®Rabbit mAb (Cell Signaling Technology) or Phospho-MEK1/2 (Ser217/221 ...
• Uncovering the mechanistic basis of intracellular Raf inhibitor sensitivity reveals synergistic cotreatment strategies

  Ethan G. Stoddard, et al., bioRxiv - Cell Biology 2024

  Quote: ... Phospho-p44/42 MAPK (Erk1/2) D13.14.4E XP®Rabbit mAb (Cell Signaling Technology), Phospho-MEK1/2 (Ser217/221 ...
• Uncovering the mechanistic basis of intracellular Raf inhibitor sensitivity reveals synergistic cotreatment strategies

  Ethan G. Stoddard, et al., bioRxiv - Cell Biology 2024

  Quote: ... Mouse mAb (Cell Signaling Technology)/Phospho-p44/42 MAPK (Erk1/2) D13.14.4E XP®Rabbit mAb (Cell Signaling Technology) were diluted in Intercept PBS Block Buffer (LicorBio ...
• Uncovering the mechanistic basis of intracellular Raf inhibitor sensitivity reveals synergistic cotreatment strategies

  Ethan G. Stoddard, et al., bioRxiv - Cell Biology 2024

  Quote: ... Mouse mAb (Cell Signaling Technology)/Phospho-p44/42 MAPK (Erk1/2) D13.14.4E XP®Rabbit mAb (Cell Signaling Technology) or Phospho-MEK1/2 (Ser217/221 ...
• Uncovering the mechanistic basis of intracellular Raf inhibitor sensitivity reveals synergistic cotreatment strategies

  Ethan G. Stoddard, et al., bioRxiv - Cell Biology 2024

  Quote: ... Mouse mAb (Cell Signaling Technology)/Phospho-p44/42 MAPK (Erk1/2) D13.14.4E XP®Rabbit mAb (Cell Signaling Technology) or Phospho-MEK1/2 (Ser217/221 ...