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451 - 500 of 1267 citations for 2 CHLOROMETHYL 6 METHOXY 1H BENZO D IMIDAZOLE since 2020

• Ellagic acid ameliorates atherosclerosis by targeting the epidermal growth factor receptor

  Ye-Wei Huang, et al., bioRxiv - Biochemistry 2023

  Quote: ... anti-ERK1/2 (4696S, Cell Signaling Technology, MA, USA), anti-phospho-ERK1/2 (4370S ...
• Serine arginine-rich splicing factor (SRSF7) cooperates with the histone methyltransferase KMT5a to promote the type I interferon response via transcriptional activation of IRF7

  Haley M. Scott, et al., bioRxiv - Immunology 2023

  Quote: ... or 2 µg of isotype control (IgG, Cell Signaling), 5ul Y701 STAT1 (Cell Signaling) ...
• Braf-mutant Schwann cells divert to a repair phenotype to induce congenital demyelinating neuropathy

  Elise Marechal, et al., bioRxiv - Developmental Biology 2024

  Quote: ... rabbit polyclonal anti-Erk1/2 (#9102; Cell Signaling Technology), rabbit monoclonal anti-Jun (60A8 ...
• Multifunctional molecular hybrid for targeted colorectal cancer cells: Integrating doxorubicin, AS1411 aptamer, and T9/U4 ASO

  Kanpitcha Jiramitmongkon, et al., bioRxiv - Molecular Biology 2024

  Quote: ... Bcl–2 (1:1000; 25 – 28 kDa, Cell signaling), and Bax (1:1000 ...
• Reorganization of innate immune cell lipid profiles by bioinspired meroterpenoids to limit inflammation

  Lorenz Waltl, et al., bioRxiv - Pharmacology and Toxicology 2024

  Quote: ... rabbit anti-MEK1/2 (1:1000; # 9122; Cell Signaling), rabbit anti-phospho-MEK1/2 (1:1000 ...
• Ezrin defines TSC1 activation at endosomal compartments through EGFR-AKT signaling

  Giuliana Giamundo, et al., bioRxiv - Cell Biology 2024

  Quote: ... rabbit anti-MAPKAPK-2 (1:1000, Cell Signaling 3042), rabbit anti-phospho-MAPKAPK-2 (Thr222 ...
• Synthetic G protein-coupled receptors for programmable sensing and control of cell behavior

  Nicholas A. Kalogriopoulos, et al., bioRxiv - Synthetic Biology 2024

  Quote: ... p44/42 MAPK (Erk1/2; Cell Signaling Technology #9107), and β-Tubulin (Cell Signaling Technology #86298).
• Viral Insulin/IGF-like Peptides Selectively Activate Host Insulin/IGF Signaling pathways during Grouper Iridovirus Infection

  Aurelien Chuard, et al., bioRxiv - Microbiology 2024

  Quote: ... p44/42 MAPK (Erk1/2) Antibody (Cell Signaling #9102); β-Actin (D6A8 ...
• Ubiquitin Ligase ITCH Regulates Life Cycle of SARS-CoV-2 Virus

  Qiwang Xiang, et al., bioRxiv - Molecular Biology 2024

  Quote: ... SARS-CoV-2 Membrane protein (Cell Signaling Technology, 15333S); SARS-CoV-2 Envelope protein (Cell Signaling Technology ...
• Ubiquitin Ligase ITCH Regulates Life Cycle of SARS-CoV-2 Virus

  Qiwang Xiang, et al., bioRxiv - Molecular Biology 2024

  Quote: ... SARS-CoV-2 Envelope protein (Cell Signaling Technology, 74698S); furin (Proteintech ...
• Proteomic analysis reveals complex interactions between PERK/ISR and MAPK1 in translational control in a phenotypic toxin model of Parkinson’s disease expressing PINTAC peptides

  Girish N Nallur, bioRxiv - Systems Biology 2024

  Quote: ... RSK1/2/3 (Cat. No. 9355; Cell Signaling Technology), pRPS6 (Cat ...
• Miro1 expression alters global gene expression, ERK1/2 phosphorylation, oxidation, and cell cycle progression

  Nathaniel Shannon, et al., bioRxiv - Cell Biology 2024

  Quote: ... total MEK1/2 (1:1000, Cell Signaling Technology #9122), Cofilin (1:1000 ...
• Dynamic and structural insights into allosteric regulation on MKP5 a dual-specificity phosphatase

  Erin Skeens, et al., bioRxiv - Biochemistry 2024

  Quote: ... and anti-phospho-ERK1/2 (Cell Signaling cat# 9101) antibodies ...
• Kinase Plasticity in Response to Vandetanib Enhances Sensitivity to Tamoxifen and Identifies Co-Treatment Strategies in Estrogen Receptor Positive Breast Cancer

  Rasha T. Kakati, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Phospho-p44/42 MAPK (Erk1/2) (Cell Signaling Technologies), RET (Abcam) ...
• The pro-apoptotic effect of chronic contractile activity-induced extracellular vesicles on Lewis Lung Carcinoma cells

  Patience O. Obi, et al., bioRxiv - Cancer Biology 2024

  Quote: ... rabbit anti-Bcl-2 (3498, Cell Signaling, 1:1000), rabbit anti-Bax (2772 ...
• XPO1 inhibition modulates the Wnt/β-catenin signaling pathway to reduce colorectal cancer tumorigenesis

  Andrew E. Evans, et al., bioRxiv - Cancer Biology 2024

  Quote: ... anti-COX-2 (1/300; Cell Signaling, Cat# 12282S), anti-Ki67 (1/200 ...
• XPO1 inhibition modulates the Wnt/β-catenin signaling pathway to reduce colorectal cancer tumorigenesis

  Andrew E. Evans, et al., bioRxiv - Cancer Biology 2024

  Quote: ... anti-COX-2 (1/1000; Cell Signaling, Cat # 12282S), anti-Actin (1/5000 ...
• PAX3-FOXO1 coordinates enhancer architecture, eRNA transcription, and RNA polymerase pause release at select gene targets

  Susu Zhang, et al., bioRxiv - Molecular Biology 2021

  Quote: ... and then incubated with primary antibodies (Myogenin, Abcam, ab1835; Myosin Heavy Chain, R&D, MAB4470; HA, Cell Signaling, (C29F4) #3724 ...
• Potassium starvation induces autophagy in yeast

  Nambirajan Rangarajan, et al., bioRxiv - Biochemistry 2020

  Quote: ... at 1:1,000 dilution in blocking buffer or glucose 6-phosphate dehydrogenase (G6PDH) antibodies (8866, Cell Signaling Technology, 1:1,000). Immunoreactive species were detected with antibodies conjugated with horseradish peroxidase (715-035-150 ...
• The E2F4/p130 repressor complex cooperates with oncogenic ΔNp73α to promote cell survival in human papillomavirus 38 E6/E7-transformed keratinocytes and in cancer cells

  Valerio Taverniti, et al., bioRxiv - Cancer Biology 2022

  Quote: Senescence was assessed using the Senescence β-Galactosidase Staining Kit at pH 6 following the manufacturer’s instructions (Cell Signaling Technology). For SAHF staining ...
• ERK1/2 Inhibition Alleviates Noise-Induced Hearing Loss While Tempering Down the Immune Response

  Richard D. Lutze, et al., bioRxiv - Neuroscience 2023

  Quote: ... Mice were sacrificed 6 days after noise exposure and whole cochlear lysates were prepared in lysis buffer (9803; Cell Signaling) after adding protease (cOmplete ULTRA Tablets 05892791001 ...
• Neuromodulation of Behavioral Specialization: Tachykinin Signaling Inhibits Task-specific Behavioral Responsiveness in Honeybee Workers

  Bin Han, et al., bioRxiv - Evolutionary Biology 2021

  Quote: ... The membranes were blocked for 2 hours at room temperature and then incubated with rabbit monoclonal anti-pERK1/2 antibody (Cell Signaling Technology, USA) and anti-rabbit horseradish peroxidase-conjugated secondary antibody (Cell Signaling Technology ...
• Using rat operant delayed match-to-sample task to identify neural substrates recruited with increased working memory load

  Christina Gobin, Lizhen Wu, Marek Schwendt, bioRxiv - Neuroscience 2020

  Quote: ... PKC substrate antibody selectively detects proteins with phosphorylated PKC consensus sites (phosphorylated Ser residues surrounded by Arg or Lys at the –2 and +2 positions and a hydrophobic residue at the +1 position, Cell Signaling, Danvers, MA). Next ...
• The protein phosphatases MoPtc1 and MoPtc2 are induced during pathogen-host interactions and play synergistic roles in regulating MAPK pathways in Magnaporthe oryzae

  Wilfred M. Anjago, et al., bioRxiv - Molecular Biology 2022

  Quote: ... phospho-p44/42 MAPK (ERK1/2) (Thr202/Tyr204) (D13.14.4E) Rabbit mAb and p44/42 MAPK (Erk1/2) antibodies (Cell Signaling Technology, Beverly, MA, USA) and affinity purified goat anti-rabbit & mouse antibody conjugated to horseradish peroxidase (Abmart ...
• Arrestin-3-assisted activation of JNK3 mediates dopaminergic behavioral and signaling plasticity in vivo

  Mohamed R. Ahmed, et al., bioRxiv - Neuroscience 2023

  Quote: ... Doubly phosphorylated (active) ERK1/2 was detected with a phospho-ERK-specific [phosphor-ERK1/2(Thr202/Tyr204)] mouse monoclonal antibody (Cell Signaling, cat.# 9106) at 1:2,000 dilution ...
• Decreased Astrocytic CCL5 by MiR-324-5p Ameliorates Ischemic Stroke Injury via CCR5/ERK/CREB Pathway

  Jingxiu Li, et al., bioRxiv - Neuroscience 2024

  Quote: ... The PVDF membranes were blocked with 5% BSA and probed with primary antibodies (phospho-ERK1/2, Abcam, ab76299; ERK1/2, Abcam, ab184699; phospho-CREB, Abcam, ab32096; CREB, Cell Signaling Technology, 9197) at 4 °C overnight ...
• Regulation of early growth response-1 (Egr-1) gene expression by Stat1-independent type I interferon signaling and respiratory viruses

  Chilakamarti V. Ramana, bioRxiv - Genomics 2020

  Quote: ... and subjected to immunoblotting with the antibodies for phosphorylated Erk-1/2 (Thr202/Tyr 204) or total Erk-1/2 from Cell Signaling Technology (Beverly, MA). Blots were visualized by enhanced chemiluminescence western detection system (Pierce ...
• Arrestin-3 agonism at D3 dopamine receptors defines a subclass of second generation antipsychotics that promotes drug tolerance

  Selin Schamiloglu, et al., bioRxiv - Neuroscience 2022

  Quote: ... blotted with mouse anti-ERK1/2 (p44/42 MAPK) and rabbit anti-phospho-ERK1/2 (p44/42 MAPK) (Cell Signaling Technologies 4696S and 4370S), both at 1:1000 in 2% BSA at room temperature for 2 hours ...
• Downstream branches of receptor tyrosine kinase signaling act interdependently to shape the face

  Nicholas Hanne, et al., bioRxiv - Developmental Biology 2024

  Quote: ... Antibodies specific to phosphorylation on ERK1/2 threonine 202 and tyrosine 204 were used to detect pERK1/2 (1:100, 4370S, Cell Signaling Technology, Danvers, MA); antibodies specific to phosphorylation of serine 473 of Akt1/2/3 were used to detect pAkt (1:300 ...
• Glutamine deficiency in solid tumors confers resistance to ribosomal RNA synthesis inhibitors

  Melvin Pan, et al., bioRxiv - Cancer Biology 2021

  Quote: ... phospho-ERK1/2 (Thr202/Tyr204) (1:500 Cell Signaling Technology), ERK1/2 (Thr202/Tyr204 ...
• Glutamine deficiency in solid tumors confers resistance to ribosomal RNA synthesis inhibitors

  Melvin Pan, et al., bioRxiv - Cancer Biology 2021

  Quote: ... phospho-MEK1/2 (Ser217/221) (1:500 Cell Signaling Technology), MEK1/2 (1:500 Cell Signaling Technology) ...
• HDAC and MAPK/ERK Inhibitors Cooperate to Reduce Viability and Stemness in Medulloblastoma

  Mariane da Cunha Jaeger, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Phospho-p44/42 MAPK (pErk1/2, 1:2000; Cell Signaling), p44/42 MAPK (Erk1/2 ...
• RAS specific protease Induces Irreversible Growth Arrest via p27 in several KRAS Mutant Colorectal Cancer cell lines

  Caleb K. Stubbs, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-p44/42 MAPK (ERK1/2, Cell Signaling Technology #4696), anti-HB-EGF (R&D Systems ...
• FCHSD2 Controls Oncogenic ERK1/2 Signaling Outcome by Regulating Endocytic Trafficking

  Guan-Yu Xiao, Sandra L. Schmid, bioRxiv - Cell Biology 2020

  Quote: ... p-ERK1/2 T202/Y204 (#4370S, 1:1000, Cell Signaling), ERK1/2 (#4695S ...
• Extracellular Superoxide Dismutase (EC-SOD) Regulates Gene Methylation and Cardiac Fibrosis During Chronic Hypoxic Stress

  Ayan Rajgarhia, et al., bioRxiv - Developmental Biology 2020

  Quote: ... and ERK 1/2 (Cell Signaling Technology, Danvers, MA, USA)
• Wnt-dependent activation of ERK mediates repression of chondrocyte fate during calvarial development

  Beatriz Ibarra, Cody Machen, Radhika P. Atit, bioRxiv - Developmental Biology 2021

  Quote: ... rabbit anti-phospho-ERK1/2 (1:1250, Cell Signaling 4370). Wide-field images were captured at 20X and 40X using the Leica DMi8 inverted microscope using the Leica Application Suite X (LASX ...
• Theobroma cacao improves bone growth by modulating defective ciliogenesis in a mouse model of achondroplasia

  L. Martin, et al., bioRxiv - Developmental Biology 2021

  Quote: ... anti-phosphorylated Erk1-2 (Thr180/Tyr182) (Cell Signaling Technology, #4370), anti-total Erk1-2 (Sigma-Aldrich ...
• Neurofibromin 1 controls metabolic balance and Notch-dependent quiescence of juvenile myogenic progenitors

  Xiaoyan Wei, et al., bioRxiv - Cell Biology 2021

  Quote: ... Rabbit anti-pErk1/2 (Cell Signaling Technology # 9101; 1:1000), Rabbit anti-Erk1/2 (Cell Signaling Technology # 9102 ...
• Neurofibromin 1 controls metabolic balance and Notch-dependent quiescence of juvenile myogenic progenitors

  Xiaoyan Wei, et al., bioRxiv - Cell Biology 2021

  Quote: ... Rabbit anti-Erk1/2 (Cell Signaling Technology # 9102; 1:1000), Mouse anti-ß-Actin (Cell Signaling Technology # 58169 ...
• Neurofibromin 1 controls metabolic balance and Notch-dependent quiescence of juvenile myogenic progenitors

  Xiaoyan Wei, et al., bioRxiv - Cell Biology 2021

  Quote: ... Rabbit anti-pErk1/2 (Cell Signaling Technology # 9101; 1:300), Rabbit anti-phosphor (s235/236)-S6 (Cell Signaling Technology # 4858 ...
• The MSP-RON axis stimulates cancer cell growth in models of triple negative breast cancer

  Rhona Millar, et al., bioRxiv - Cancer Biology 2020

  Quote: ... lnti-phospho-ERK1/2 (250ng/mL, Cell Signaling Technology, #4370); anti-ERK1/2 (84ng/mL ...
• Glycosyltransferase POMGNT1 deficiency affects N-cadherin-mediated cell-cell adhesion

  Sina Ibne Noor, et al., bioRxiv - Biochemistry 2020

  Quote: ... Rabbit anti-Phospho-ERK1/2(Thr202/Tyr204) (#9101, Cell Signaling), 1:1000 ...
• Glycosyltransferase POMGNT1 deficiency affects N-cadherin-mediated cell-cell adhesion

  Sina Ibne Noor, et al., bioRxiv - Biochemistry 2020

  Quote: ... Rabbit anti-Phospho-MEK1/2(Ser217/221) (#9121, Cell Signaling), 1:1000 ...
• The Peroxiredoxin 6 gene plays a critical role in the homeostatic regulation of fear response

  Sarayut Phasuk, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-total ERK1/2 (1:1000; Cell Signaling, Danvers, MA), anti-PSD95 (1:2000 ...
• The Imprinted Igf2-Igf2r Axis is Critical for Matching Placental Microvasculature Expansion to Fetal Growth

  Ionel Sandovici, et al., bioRxiv - Developmental Biology 2021

  Quote: ... rabbit anti-p44/42 MAPK (Erk1/2) (Cell Signaling, 9102), rabbit anti-Phospho-Akt (Ser473 ...
• Phosphatidylserine binding regulates TIM-3 effects on T cell receptor signaling

  Courtney M. Smith, et al., bioRxiv - Biochemistry 2021

  Quote: ... anti-ERK1/2 pT202/pY204 (Cell Signaling Technology, catalog #9106), anti-Grb2 (Cell Signaling Technology ...
• Sex and Circuit Specific Dopamine Transporter Regulation Underlies Unique Behavioral Trajectories of Functional SLC6A3 Coding Variation

  Adele Stewart, et al., bioRxiv - Neuroscience 2021

  Quote: ... and phospho-ERK 1/2 (Cell Signaling, RRID:AB_331646; 1:1000).) ...
• The CoREST Repressor Complex Mediates Phenotype Switching and Therapy Resistance in Melanoma

  Muzhou Wu, et al., bioRxiv - Cancer Biology 2020

  Quote: ... p44/42 MAPK (Erk1/2) (Cell Signaling, 9102s, 1:1000), MITF (Cell Signaling ...
• Hemangiosarcoma cells induce M2 polarization and PD-L1 expression in macrophages

  Kevin Christian M. Gulay, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-ERK1/2 antibody (1:1000; Cell Signaling Technology, 4695S), anti-H2AK119Ub1 antibody (1:2000 ...
• A phosphorylation of RIPK3 kinase initiates an intracellular apoptotic pathway that promotes corpus luteum regression

  Dianrong Li, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-Phospho-MEK1/2 (9154S, Cell Signaling; WB, 1:1000), anti-MEK1/2 (ab178876 ...