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1551 - 1600 of 10000+ citations for Flap endonuclease 1 FEN 1 Human since 2019

• Lipid-siRNA conjugate accesses a perivascular transport mechanism and achieves widespread and durable knockdown in the central nervous system

  Alexander G. Sorets, et al., bioRxiv - Bioengineering 2024

  Quote: ... AQP4-488 (1:500 for overnight or 1:200 for 2 hours, Abcam ab284135), Glut1-PE (1:300 ...
• A stronger transcription regulatory circuit of HIV-1C drives the rapid establishment of latency with implications for the direct involvement of Tat

  Sutanuka Chakraborty, et al., bioRxiv - Microbiology 2020

  Quote: ... HIV-1 Tat (ab43014, Abcam or #7377 ...
• Resistance to chemical carcinogenesis induction via a dampened inflammatory response in naked mole-rats

  Kaori Oka, et al., bioRxiv - Cancer Biology 2021

  Quote: ... pMLKL (Abcam, ab196436; 1:1000), cleaved caspase-3 (CST ...
• Paradoxical Roles of Peritumoral Myofibroblasts in Intrahepatic Cholangiocarcinoma Growth and Metastasis

  Cheng Tian, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Vcam1 (Abcam, ab134047, 1:1000) and anti-CD68 (Abcam ...
• Sister chromatid exchanges induced by perturbed replication are formed independently of homologous recombination factors

  Anne Margriet Heijink, et al., bioRxiv - Cancer Biology 2021

  Quote: ... MUS81 (Abcam, ab14387, 1:1000), ERCC1 (Cell Signaling ...
• Inhibition of Metastatic Uveal Melanoma Cell Proliferation by the Histone Deacetylase 6 Inhibitor, Ricolinostat, is Linked to Altered Microphthalmia-associated Transcription Factor and Phospho-ERK Expression

  Husvinee Sundaramurthi, et al., bioRxiv - Cancer Biology 2021

  Quote: ... MITF (1:1000; #ab122982, Abcam kindly provided by Dr ...
• The coagulation factor IX (F9) loss of function prevents the cell cycle arrest induced by CDK4/6 inhibitors treatment

  Paula Carpintero-Fernández, et al., bioRxiv - Cancer Biology 2021

  Quote: ... BrdU (Abcam, ab6326; 1:500) and F9 (Proteintech ...
• Emerging single cell endothelial heterogeneity supports sprouting tumour angiogenesis and growth

  Ken Matsumoto, et al., bioRxiv - Cancer Biology 2021

  Quote: ... CD31 (1:100, ab28364, Abcam), F4/80 (1:100 ...
• CHRM1 is a Druggable Melanoma Target Whose Endogenous Activity is Determined by Inherited Genetic Variation in DOPA Production

  Miriam Doepner, et al., bioRxiv - Cancer Biology 2021

  Quote: ... tyrosinase (Abcam, T311, 1:1000), p53 (Cell Signaling Technology ...
• Profiling tumor immune microenvironment of non-small cell lung cancer using multiplex immunofluorescence

  Haoxin Peng, et al., bioRxiv - Cancer Biology 2021

  Quote: ... CD20 (ab9475, abcam, 1:50), Zsbio ...
• MAGI2-AS3 modulates proliferation, apoptosis and glycolysis in acute lymphoblastic leukemia via miR-452-5p/FOXN3 axis

  Xiao-Guang Chen, et al., bioRxiv - Cancer Biology 2021

  Quote: ... HK2 (ab209847, 1:1000, Abcam), FOXN3 (#711585 ...
• Loss of Smad4 promotes aggressive lung cancer metastasis by de-repression of PAK3 via miRNA regulation

  Xiaohong Tan, et al., bioRxiv - Cancer Biology 2021

  Quote: ... TTF1 (Abcam ab76013, 1:200). Covered sections with detection reagent for 20 minutes at RT ...
• Cdk5 drives formation of heterogeneous pancreatic neuroendocrine tumors

  Angela M. Carter, et al., bioRxiv - Cancer Biology 2021

  Quote: ... insulin (Abcam ab63820; 1:2000), glucagon (Santa Cruz sc7779 ...
• Cdk5 drives formation of heterogeneous pancreatic neuroendocrine tumors

  Angela M. Carter, et al., bioRxiv - Cancer Biology 2021

  Quote: ... somatostatin (Abcam ab108456; 1:450). Biotinylated secondary antibodies (Pierce 31820 or 31800 ...
• Characterization of highly proliferative decidual precursor cells during the window of implantation in human endometrium

  Maria Diniz-da-Costa, et al., bioRxiv - Cell Biology 2020

  Quote: ... or CD163 (1:200, Abcam). Labelled cells were stained with Alexa Fluor™ 594 anti-mouse secondary antibody and Alexa Fluor™ 488 anti-rabbit secondary antibody ...
• Zbtb24 binding protects promoter activity by antagonizing DNA methylation in mESCs

  Haoyu Wu, et al., bioRxiv - Molecular Biology 2019

  Quote: ... Dnmt3a (ab13888; Abcam, 1:1000), Dnmt3b (Ab16049 ...
• Human NMD ensues independently of stable ribosome stalling

  Evangelos D. Karousis, et al., bioRxiv - Molecular Biology 2019

  Quote: ... ABCE1 (Abcam, ab185548, 1:1000), beta-actin (Sigma Aldrich A5060 ...
• BRAF inhibitors reprogram cancer-associated fibroblasts to drive matrix remodeling and therapeutic escape in melanoma

  Tianyi Liu, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Akt1 (Abcam, ab32505, 1:1000), p-Akt1 (Abcam ...
• Aryl Hydrocarbon Receptor Blocks Aging-Induced Senescence in the Liver and Fibroblast Cells

  Ana Nacarino-Palma, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-p21Cip1 (Abcam, 1:100), anti-α-SMA (Sigma 1:200 ...
• A Versatile Polypharmacology Platform Promotes Cytoprotection and Viability of Human Pluripotent and Differentiated Cells

  Yu Chen, et al., bioRxiv - Cell Biology 2019

  Quote: ... SOX17(Abcam, 84990, 1:50), PAX6 (BioLegend ...
• Rapidly cycling stem cells regenerate the intestine independent of Lgr5^high cells

  Xiaole Sheng, et al., bioRxiv - Cell Biology 2019

  Quote: ... pH3 (Abcam, ab14955, 1:200), BrdU (Abcam ...
• Rapidly cycling stem cells regenerate the intestine independent of Lgr5^high cells

  Xiaole Sheng, et al., bioRxiv - Cell Biology 2019

  Quote: ... BrdU (Abcam, ab6326, 1:100), PCNA (Abcam ...
• Rapidly cycling stem cells regenerate the intestine independent of Lgr5^high cells

  Xiaole Sheng, et al., bioRxiv - Cell Biology 2019

  Quote: ... GFP (Abcam, ab290, 1:800), RFP (ROCKLAND ...
• Rapidly cycling stem cells regenerate the intestine independent of Lgr5^high cells

  Xiaole Sheng, et al., bioRxiv - Cell Biology 2019

  Quote: ... ChgA (Abcam, ab15160, 1:400), Mucin2 (Santa Cruz ...
• Rapidly cycling stem cells regenerate the intestine independent of Lgr5^high cells

  Xiaole Sheng, et al., bioRxiv - Cell Biology 2019

  Quote: ... GFP (Abcam, ab13970, 1:800), GFP (Abcam ...
• Rapidly cycling stem cells regenerate the intestine independent of Lgr5^high cells

  Xiaole Sheng, et al., bioRxiv - Cell Biology 2019

  Quote: ... PCNA (Abcam, ab92552, 1:200), GFP (Abcam ...
• The M-phase regulatory phosphatase PP2A-B55δ opposes protein kinase A on Arpp19 to initiate meiotic division

  Tom Lemonnier, et al., bioRxiv - Cell Biology 2019

  Quote: ... PKI (1:1000, Abcam ab122816), PP1 catalytic subunit (1:100 ...
• The primary cilium dampens proliferative signaling and represses a G2/M transcriptional network in quiescent myoblasts

  Nisha Venugopal, et al., bioRxiv - Cell Biology 2019

  Quote: ... GAPDH (Abcam, ab9484, 1:2000), Myogenin (Santa Cruz ...
• The primary cilium dampens proliferative signaling and represses a G2/M transcriptional network in quiescent myoblasts

  Nisha Venugopal, et al., bioRxiv - Cell Biology 2019

  Quote: ... Ki67 (Abcam, ab1667, 1:200), Myogenin (Santa Cruz ...
• The primary cilium dampens proliferative signaling and represses a G2/M transcriptional network in quiescent myoblasts

  Nisha Venugopal, et al., bioRxiv - Cell Biology 2019

  Quote: ... Hes1 (Abcam, ab71559, 1:500), Phospho - mTOR (CST ...
• BET Bromodomain Proteins Regulate Transcriptional Reprogramming in Genetic Dilated Cardiomyopathy

  Andrew Antolic, et al., bioRxiv - Cell Biology 2020

  Quote: ... 1:500 VeriBlot (Abcam, #ab131366) was used as the secondary antibody for all IP detection experiments.
• NRP2 as an emerging angiogenic player; promoting endothelial cell adhesion and migration by regulating recycling of α5 integrin

  Abdullah AA Alghamdi, et al., bioRxiv - Cell Biology 2020

  Quote: ... prox-1 (clone ab11941, Abcam), claudin-5 (clone ab131259 ...
• BLOS1 mediates kinesin switch during endosomal recycling of LDL receptor

  Chang Zhang, Chanjuan Hao, Guanghou Shui, Wei Li, bioRxiv - Cell Biology 2020

  Quote: ... anti-HA (Abcam, 1/5000).
• Activation of FAM111A Protease Induces Defects in Nuclear Function that Likely Underlie its Roles in Disease and Viral Restriction

  Minghua Nie, et al., bioRxiv - Cell Biology 2020

  Quote: ... SV40LT (Abcam, ab16879 (1:3000)) ...
• Activation of FAM111A Protease Induces Defects in Nuclear Function that Likely Underlie its Roles in Disease and Viral Restriction

  Minghua Nie, et al., bioRxiv - Cell Biology 2020

  Quote: ... SV40LT (Abcam, ab16879 (1:250)) ...
• Boron induces osteogenesis by stimulating NaBC1 in cooperation with BMPR1A

  Patricia Rico, et al., bioRxiv - Cell Biology 2020

  Quote: ... active YAP (abcam, 1:500) were used ...
• Boron induces osteogenesis by stimulating NaBC1 in cooperation with BMPR1A

  Patricia Rico, et al., bioRxiv - Cell Biology 2020

  Quote: ... integrin α5 (abcam, 1:500) and anti-integrin αv (abcam ...
• Rapidly induced drug adaptation mediates escape from BRAF inhibition in single melanoma cells

  Chen Yang, et al., bioRxiv - Cell Biology 2020

  Quote: ... MITF (1:100) (Abcam, #ab3201), NGFR (1:1000 ...
• Gain-of-function mutations amplify cytotoxic FAM111 protease activity in human genetic disorders

  Saskia Hoffmann, et al., bioRxiv - Cell Biology 2020

  Quote: ... FAM111A (ab184572, Abcam (1:1,000)) ...
• Gain-of-function mutations amplify cytotoxic FAM111 protease activity in human genetic disorders

  Saskia Hoffmann, et al., bioRxiv - Cell Biology 2020

  Quote: ... RFC1 (ab3566, Abcam (1:1,000)) ...
• Gain-of-function mutations amplify cytotoxic FAM111 protease activity in human genetic disorders

  Saskia Hoffmann, et al., bioRxiv - Cell Biology 2020

  Quote: ... FAM111A (ab184572, Abcam (1:300)) ...
• Gain-of-function mutations amplify cytotoxic FAM111 protease activity in human genetic disorders

  Saskia Hoffmann, et al., bioRxiv - Cell Biology 2020

  Quote: ... RFC3 (ab154899, Abcam (1:1,000)) ...
• Single-molecule imaging reveals translation of mRNAs localized to stress granules

  Daniel Mateju, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit TIA-1 (Abcam, ab40693), rabbit DDX6 (Bethyl ...
• Boron induces osteogenesis by stimulating NaBC1 in cooperation with BMPR1A

  Patricia Rico, et al., bioRxiv - Cell Biology 2020

  Quote: ... Collagen I (abcam, 1:200) as primary antibodies ...
• Boron induces osteogenesis by stimulating NaBC1 in cooperation with BMPR1A

  Patricia Rico, et al., bioRxiv - Cell Biology 2020

  Quote: ... integrin αv (abcam, 1:500), pSmad1 (Cell Signalling ...
• Boron induces osteogenesis by stimulating NaBC1 in cooperation with BMPR1A

  Patricia Rico, et al., bioRxiv - Cell Biology 2020

  Quote: ... active YAP (abcam, 1:500), NaBC1 (abcam ...
• Phase-separation of EML4-ALK variant 3 is dependent upon an active ALK conformation

  Josephina Sampson, et al., bioRxiv - Cell Biology 2020

  Quote: ... GFP (1:1000; abcam 6556), ALK rabbit (D5F3 ...
• Gorlin syndrome-induced pluripotent stem cells form medulloblastoma with loss of heterozygosity in PTCH1

  Yu Ikemoto, et al., bioRxiv - Cell Biology 2019

  Quote: ... Ki-67 (1:100, Abcam), p53 (DAKO ...
• Osteoblast-osteoclast co-culture amplifies inhibitory effects of FG-4592 on osteoclast formation and reduces bone resorption activity

  Philippa A Hulley, et al., bioRxiv - Cell Biology 2019

  Quote: ... GLUT1 (ab14683, 1:2500; Abcam) or β-tubulin (clone TUB2.1 ...
• CENP-A chromatin prevents replication stress at centromeres to avoid structural aneuploidy

  Simona Giunta, et al., bioRxiv - Cell Biology 2020

  Quote: ... SMARCAL1 (1:200; Ab154226; Abcam). All secondary antibodies used for immunofluorescence microscopy were purchased from Jackson Immuno Research ...