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1501 - 1550 of 10000+ citations for Flap endonuclease 1 FEN 1 Human since 2019

• PSMA-bearing extracellular vesicles secreted from prostate cancer convert the microenvironment to a tumor-supporting, pro-angiogenic state

  Camila Maria Longo Machado, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Further steps included primary antibody incubations (anti-PSMA-AbCam (AB1971,YPSMA-1, 1:2,000), anti-PSMA (J591 ...
• Efficacy and sex differences in the effects on rat brain microglia of the colony-stimulating factor 1 receptor inhibitor-PLX5622

  Aviv Sharon, Hadas Erez, Micha E. Spira, bioRxiv - Neuroscience 2022

  Quote: Microglia were labeled using rabbit anti-Ibl-1 monoclonal antibody (Abcam ab178846, 1:2000). For the secondary antibodies we used sheep anti-rabbit Cy3 (Sigma–Aldrich C2306 ...
• Rapid generation of ventral spinal cord-like astrocytes from human iPSCs for modeling non-cell autonomous mechanisms of lower motor neuron disease

  Vincent Soubannier, et al., bioRxiv - Neuroscience 2021

  Quote: ... and rabbit anti-SLC1A2/EAAT2/GLT-1 (SLC1A2) (1/500; Abcam; Cat. No. 41621). Secondary antibodies against primary reagents raised in various species were conjugated to Alexa Fluor 555 and Alexa Fluor 488 (1/1,000 ...
• Ultrastructural analysis of neuroimplant-parenchyma interfaces uncover remarkable neuroregeneration along-with barriers that limit the implant electrophysiological functions

  Aviv Sharon, et al., bioRxiv - Neuroscience 2021

  Quote: ... Microglia were labelled using rabbit anti-Iba-1 monoclonal antibody (Abcam ab178846, 1:1000). For the secondary antibodies we used goat anti-mouse Alexa 488 ...
• Nanoparticle-mediated transgene expression of insulin-like growth factor 1 in the growth restricted guinea pig placenta increases placenta nutrient transporter expression and fetal glucose concentrations

  Rebecca L. Wilson, et al., bioRxiv - Physiology 2022

  Quote: ... Primary antibodies (Slc2A1: Abcam ab15309 1:500, Slc2A3: Abcam ab15311 1:200, Slc38A1: Abcam ab104684 1:200 ...
• Coordinated regulation of CB1 cannabinoid receptors and anandamide metabolism stabilizes network activity during homeostatic downscaling

  Michael Ye, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-PSD95 (NeuroMab 75-028, 1:1,000,000) and anti-α-Tubulin (Abcam, 1:50,000). The following rabbit primary antibodies were used ...
• Cell-type specific concentration regulation of the basal transcription factor TFIIH

  Lise-Marie Donnio, et al., bioRxiv - Cell Biology 2019

  Quote: ... TBP (1/200, rabbit, cell signalling 8515S) and p62 (1/100, rabbit, abcam ab204168). After several washes with PBS 0.1% triton X-100 ...
• Lipid droplets disrupt mechanosensing in human hepatocytes

  LiKang Chin, et al., bioRxiv - Physiology 2020

  Quote: ... primary antibodies (rabbit anti-YAP, 1:100; rabbit anti-vinculin, 1:100, ab129002, Abcam, Cambridge ...
• Jag1 modulates an oscillatory Dll1-Notch-Hes1 signaling module to coordinate growth and fate of pancreatic progenitors

  Philip A. Seymour, et al., bioRxiv - Developmental Biology 2019

  Quote: ... at 1:1000 and rat monoclonal anti-tubulin at 1:5000 (Abcam, Cambridge, UK).
• A novel computational method to design BH3-mimetic peptide inhibitors that can bind specifically to Mcl-1 or Bcl-X_L

  C. Narendra Reddy, et al., bioRxiv - Biophysics 2020

  Quote: ... 1:1000 diluted Cleaved PARP (Asp214) and 1:5000 diluted β-actin (Abcam, ab6276). Subsequently ...
• Perivascular tenascin C triggers sequential activation of macrophages and endothelial cells to generate a pro-metastatic vascular niche in the lungs

  Tsunaki Hongu, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-CD31 (Mec13.3, 1:100 dilution, BD Pharmingen, or ab28364, 1:50 dilution, abcam), anti-cleaved caspase 3 (D3E9 ...
• IFT88 controls NuMA enrichment at k-fibers minus-ends to facilitate their reincorporation into mitotic spindles

  Nicolas TAULET, et al., bioRxiv - Cell Biology 2019

  Quote: ... NuMA (Santa-Cruz sc-365532 IF: 1:200; Abcam ab-36999 WB:1/500) and DAPI (Cell signaling ...
• Skeletal Phenotype and Mechanisms of Bone Loss in Winnie Mice as a Model for Inflammatory Bowel Disease

  Ahmed Al Saedi, et al., bioRxiv - Physiology 2020

  Quote: ... incubated with goat anti-type 1 collagen antibody (Ab) (1:100, ab34710, Abcam, UK) overnight at RT ...
• Calmodulin binds to the N-terminal domain of the cardiac sodium channel Na_v1.5

  Zizun Wang, et al., bioRxiv - Physiology 2020

  Quote: ... and mouse anti-alpha-1 sodium-potassium ATPase (1:3000; Abcam, Cambridge, UK; ab7671). Secondary IRDye® antibodies (Li-Cor ...
• Cavin3 released from caveolae interacts with BRCA1 to regulate the cellular stress response

  Kerrie-Ann McMahon, et al., bioRxiv - Cancer Biology 2020

  Quote: ... mouse anti-BRCA1 MS110 (ab16780, 1:1000 WB, 1:100 IF/PLA, Abcam, Australia), rabbit anti-BRCA1 (07-434 ...
• Differential expression levels of Sox9 in early neocortical radial glial cells regulate the decision between stem cell maintenance and differentiation

  Jaime Fabra-Beser, et al., bioRxiv - Neuroscience 2020

  Quote: ... rabbit anti-Sox9 (1:1000, Abcam, #AB184547; rabbit anti-Tle4 (1:500, Abcam, #ab140485); rabbit anti-Tbr2 (Eomes ...
• Intercellular telomere transfer extends T cell lifespan

  Bruno Vaz, et al., bioRxiv - Immunology 2020

  Quote: ... Activated T cells were stained with antibodies to sestrin 1 (1:300, ab134091, Abcam). Shelterin expression in APCs was evaluated with antibodies to TRF2 and POT1 as per telomere vesicles.
• Chromosome length and gene density contribute to micronuclear membrane stability

  Anna E Mammel, et al., bioRxiv - Cell Biology 2021

  Quote: ... mouse or rabbit anti-H3K27ac (1:250; 39085, Active Motif; 1:1000; ab4729, Abcam), rabbit anti-Lamin B1 (1:100 ...
• DamID transcriptional profiling identifies the Snail/Scratch transcription factor Kahuli as Alk target in the Drosophila visceral mesoderm

  Patricia Mendoza-Garcia, et al., bioRxiv - Developmental Biology 2021

  Quote: ... mouse anti-Antp (1:50; DSHB 4C3) rabbit anti-GFP (1:500; Abcam ab290), chicken anti-GFP (1:300 ...
• A chromatin phase transition protects mitotic chromosomes against microtubule perforation

  Maximilian W. G. Schneider, et al., bioRxiv - Cell Biology 2021

  Quote: ... Pericentrin was detected with a recombinant rabbit antibody (Abcam, ab220784, GR3284309-1, 1:2000) and visualized using a goat anti-rabbit Alexa Fluor 633 secondary antibody (Molecular Probes ...
• Genome-wide CRISPR/Cas9 Screens Reveal Shared and Bespoke Mechanisms of Resistance to SHP2 inhibition

  Wei Wei, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Antibodies against MAP4K5 (#ab96551, 1:1000) and MRAS (#ab176570, 1:1000) were from Abcam. Pan-RAS antibody (Ab-3 ...
• Exosome-derived lncRNA HOXA-AS3 promotes castration resistance and progression of prostate cancer via the miR-29b-3p/Mcl-1/STAT3 axis

  Jie Teng, et al., bioRxiv - Genomics 2022

  Quote: ... The membranes were then probed with antibodies(1:1000) against MCL-1 (abcam, ab32087), STAT3 (abcam ...
• Neutrophils initiate the destruction of the olfactory epithelium during SARS-CoV-2 infection in hamsters

  Bourgon Clara, et al., bioRxiv - Immunology 2022

  Quote: ... ionised calcium-binding adapter molecule 1 (Iba1) (1/500; rabbit monoclonal; clone EPR16588; Abcam), myeloperoxidase protein (MPO ...
• Vascular Smooth Muscle Cell Mechanotransduction Through Serum and Glucocorticoid Inducible Kinase -1 Promotes Interleukin-6 Production and Macrophage Accumulation in Murine Hypertension

  Mario Figueroa, et al., bioRxiv - Physiology 2023

  Quote: ... and incubated in antisera specific for SGK-1 (ab32374, AbCam, Waltham, MA; 1:1000), pSGK-1 (ab55281 ...
• N-myc Downstream Regulated Gene 1 (NDRG1) functions as a molecular switch for cellular adaptation to hypoxia

  Jong S. Park, et al., bioRxiv - Developmental Biology 2022

  Quote: ... Goat anti-mouse Alexa Fluor 488 @ 1:500 (Abcam, catalog # ab150113, Lot#GR3373409-1). Other labels added after secondary antibodies ...
• Dimethyl fumarate modulates the Duchenne muscular dystrophy disease program following short-term treatment in mdx mice

  Cara A. Timpani, et al., bioRxiv - Pathology 2022

  Quote: ... anti-phospho-STAT3 (1:2000; #9145; CST) and anti-TFAM (1:1000; ab252432; Abcam). Membranes were probed with a horseradish peroxidase-conjugated secondary antibody (1:5000 ...
• Mechanisms by which barrier-to-autointegration factor regulates dynamics of nucleocytoplasmic leakage and membrane repair following nuclear envelope rupture

  Charles T. Halfmann, et al., bioRxiv - Cell Biology 2023

  Quote: ... Cells were labeled for 1 hr with rabbit anti-BAF (1:100; ab129184; Abcam), rabbit anti-Emerin (1:100 ...
• Glia-derived secretory fatty acid binding protein Obp44a regulates lipid storage and efflux in the developing Drosophila brain

  Jun Yin, et al., bioRxiv - Developmental Biology 2024

  Quote: ... including rabbit anti-Obp44a (1:5000) or rabbit anti-GFP (Abcam, ab6556, 1:2000), or rabbit anti-alpha tubulin (Abcam ...
• The transcription factor Tcf21 is required for specifying Foxd1 cells to the juxtaglomerular cell lineage

  Hina Anjum, et al., bioRxiv - Developmental Biology 2024

  Quote: ... Antibody information: CD31 (R&D, AF3628, 1:200) and CD146 (abcam, ab75769, 1:200), Krt8 (TROMA-I-s ...
• Transcriptional perturbation of LINE-1 elements reveals their cis-regulatory potential

  Yuvia A Pérez-Rico, et al., bioRxiv - Genomics 2024

  Quote: ... Primary antibodies were as follows: rabbit anti-LINE-1 ORF1 (1:1000; Abcam, ab216324) and rabbit anti-Cas9 (1:100 ...
• MARK2/MARK3 kinases are catalytic co-dependencies of YAP/TAZ in human cancer

  Olaf Klingbeil, et al., bioRxiv - Cancer Biology 2024

  Quote: ... p-LATS1/2 (T1079/T1041) (Cell Signaling, D57D3, Abcam, ab305029, 1:1,000 – 1:3,000), cJUN (Cell Signaling ...
• Lysosomal uptake of mtDNA mitigates heteroplasmy

  Parisa Kakanj, et al., bioRxiv - Cell Biology 2024

  Quote: ... α-RAB5 (ab109534; 1:1000) and monoclonal α-ATP5A (ab14748; 1:1000) from Abcam; polyclonal α-LAMP1 (#9091 ...
• A Zika virus protein expression screen in Drosophila to investigate targeted host pathways during development

  Nichole Link, et al., bioRxiv - Developmental Biology 2023

  Quote: ... Primary antibodies include rat anti-Deadpan (Abcam Cat# ab195172, 1:250 or 1:500), mouse anti- Prospero (Developmental Studies Hybridoma Bank ...
• Ulinastatin Ameliorates Cardiac Ischemia/Reperfusion Injury via Inhibiting the tissue kallikrein-kinin system

  Xiao Ran, et al., bioRxiv - Cell Biology 2023

  Quote: ... rabbit Anti-VEGF (CatNo.ab52917, Abcam; 1:1000 for WB and 1:200 for IF), rabbit Anti- IL-1β (CatNo ...
• Exonuclease assisted mapping of protein-RNA interactions (ePRINT)

  Sophie Hawkins, et al., bioRxiv - Genomics 2023

  Quote: ... Primary antibodies (FUS 1:100 Santa Cruz Biotech sc-47711; ISL1 1:500 Abcam ab109517 ...
• Epigenetic reprogramming of a distal developmental enhancer cluster drives SOX2 overexpression in breast and lung cancer

  Luis E. Abatti, et al., bioRxiv - Genomics 2023

  Quote: ... followed by incubation for 1 hour in Rabbit anti-SOX2 (Abcam, ab92494, 1:500). After washes ...
• Accurate quantification of lysyl oxidase concentration in human tissue

  Yimin Yao, et al., bioRxiv - Molecular Biology 2023

  Quote: ... Secondary antibodies used were goat anti-rabbit (Abcam, ab6721, 1:5000 or 1:10000) or rabbit anti-goat (Abcam ...
• An unconventional mechanism of IL-1β secretion that requires Type I IFN in lupus monocytes

  Simone Caielli, et al., bioRxiv - Immunology 2023

  Quote: Active caspase-1 was quantified by using the Caspase-1 Assay Kit Colorimetric (Abcam) according to the manufacturer’s instructions.
• CDK4/6 inhibition enhances SHP2 inhibitor efficacy and is dependent upon restoration of RB function in malignant peripheral nerve sheath tumors

  Jiawan Wang, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Primary antibody anti-Ki-67 (1:200 dilution; #Ab16667, lot number GR3185488-1, Abcam) was applied at 36°C for 60 minutes ...
• Arginine shortage induces replication stress and confers genotoxic resistance by inhibiting histone H4 translation and promoting PCNA polyubiquitination

  Yi-Chang Wang, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-histone H4 (1:10000 or 1:500 for long exposure; Cat# ab177840, abcam), anti-lamin A/C (1:2000 ...
• Ulinastatin Ameliorates Cardiac Ischemia/Reperfusion Injury via Inhibiting the tissue kallikrein-kinin system

  Xiao Ran, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse Anti-eNOS (CatNo.ab76198, Abcam; 1:1000 for WB and 1:200 for IF), rabbit Anti-VEGF (CatNo.ab52917 ...
• TGFβ controls alveolar type 1 epithelial cell plasticity and alveolar matrisome gene transcription

  Danielle A. Callaway, et al., bioRxiv - Cell Biology 2023

  Quote: ... GFP (chicken, Aves Labs, GFP-1020, 1:200 or goat, Abcam, ab6673, 1:200), Ki67 (mouse ...
• PLK4 homodimerization is required for CEP152 centrosome localization and spindle organization

  Harshita Kasera, Priyanka Singh, bioRxiv - Cell Biology 2023

  Quote: ... anti-PLK4 rabbit polyclonal (Abcam, #ab137398, 1:2000 in WB, 1:50 in IF), anti-CEP152 rabbit polyclonal (Abcam ...
• VLP-mediated delivery of structure-selected neoantigens demonstrates immunogenicity and antitumoral activity in mice

  Ana Barajas, et al., bioRxiv - Immunology 2023

  Quote: ... membranes were incubated with primary antibody anti-HIV-1 p24 antibody (Abcam, 1:2000) and secondary antibody Peroxidase AffiniPure Donkey anti-Mouse IgG (H+L ...
• The V-ATPase/ATG16L1 axis is controlled by the V₁H subunit

  Lewis Timimi, et al., bioRxiv - Molecular Biology 2023

  Quote: ... mouse monoclonal anti-IAV matrix 2 (Abcam, ab5416, WB 1:1000, IF 1:100), mouse monoclonal anti-β-actin (Proteintech ...
• Inflammation and autophagy dysfunction in metachromatic leukodystrophy: a central role for mTOR?

  Zoe Catchpole, et al., bioRxiv - Neuroscience 2024

  Quote: ... Primary antibodies (anti-p62, Abcam ab207305, 1:1,000; anti-LC3B, Abcam ab48394, 1:200) were made up in 10% normal goat serum in TBS-T and incubated overnight at 4°C ...
• Lipid-siRNA conjugate accesses a perivascular transport mechanism and achieves widespread and durable knockdown in the central nervous system

  Alexander G. Sorets, et al., bioRxiv - Bioengineering 2024

  Quote: ... AQP4-488 (1:500 for overnight or 1:200 for 2 hours, Abcam ab284135), Glut1-PE (1:300 ...
• IL-6 SIGNALING EXACERBATES HALLMARKS OF CHRONIC TENDON DISEASE BY STIMULATING REPARATIVE FIBROBLASTS

  Tino Stauber, et al., bioRxiv - Bioengineering 2024

  Quote: ... and a GFP-antibody (Abcam, ab290, 1:500 in PBS-T with 1% BSA) to those from the three-week timepoint ...
• ProteasomeID: quantitative mapping of proteasome interactomes and substrates for in vitro and in vivo studies

  Aleksandar Bartolome, et al., bioRxiv - Biochemistry 2024

  Quote: ... anti-Proteasome 20S alpha 1+2+3+5+6+7 (1:200, Abcam, ab22674), anti-GFP (Santa Cruz ...
• mitoBK_Ca is functionally expressed in murine and human breast cancer cells and potentially contributes to metabolic reprogramming

  Helmut Bischof, et al., bioRxiv - Cancer Biology 2024

  Quote: ... or anti-alpha 1 sodium potassium ATPase (Abcam, Berlin, Germany, no. ab7671, 1:1,000). This was followed by incubation with a secondary anti-rabbit (Thermo Fisher Scientific ...