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2051 - 2100 of 10000+ citations for 7 Amino 1 3 dimethyl 1H 8H pyrido 2 3 d pyrimidine 2 4 5 trione since 2020

• Lumican regulates cervical corticospinal axon collateralization via non-autonomous crosstalk between distinct corticospinal neuron subpopulations

  Yasuhiro Itoh, et al., bioRxiv - Neuroscience 2021

  Quote: ... goat anti-Lumican (R&D Systems, AF2745, 1:200). HRP-conjugated secondary antibodies (Abcam ...
• Single cell transcriptomics reveals functionally specialized vascular endothelium in brain

  Hyun-Woo Jeong, et al., bioRxiv - Physiology 2022

  Quote: ... goat anti CD31 (R&D Systems AF3628, 1:200), rabbit anti-CD206 (Abcam ab64693 ...
• Single cell transcriptomics reveals functionally specialized vascular endothelium in brain

  Hyun-Woo Jeong, et al., bioRxiv - Physiology 2022

  Quote: ... goat anti-Olig2 (R&D Systems AF2418, 1:100), rabbit anti-MHC Class II (Abcam ab180779 ...
• Expression and T cell Regulatory Action of the PD-1 Immune Checkpoint in the Ovary and Fallopian Tube

  Joshua Johnson, et al., bioRxiv - Physiology 2020

  Quote: ... PD-1 blocking antibody (R&D Systems/Techne, #AF1086) was included at the 10 µg/ml ...
• Robo recruitment of the Wave Regulatory Complex plays an essential and conserved role in midline repulsion

  Karina Chaudhari, et al., bioRxiv - Developmental Biology 2020

  Quote: ... goat anti-Robo3 (1:200, R&D systems, #AF3076), Cy3 donkey anti-goat (1:500 ...
• Dot1L methyltransferase activity is a barrier to acquisition of pluripotency but not transdifferentiation

  Coral K. Wille, Rupa Sridharan, bioRxiv - Developmental Biology 2020

  Quote: ... anti-human NANOG (R&D Systems AF1997, 1:100), anti-TUJ1 (Novus Biologicals MAB1195 ...
• Male sex hormones increase excitatory neuron production in developing human neocortex

  Iva Kelava, et al., bioRxiv - Developmental Biology 2020

  Quote: ... sheep anti-TBR2 (R&D Systems, AF6166, 1:200).
• Ferroptotic stress promotes the accumulation of pro-inflammatory proximal tubular cells in maladaptive renal repair

  Shintaro Ide, et al., bioRxiv - Cell Biology 2021

  Quote: ... KIM1 (R&D Systems, Minneapolis, MN, AF1817, 1:400), NGAL (Abcam ...
• TRPM2 deficiency protects against atherosclerosis by inhibiting TRPM2-CD36 inflammatory axis in macrophages

  Pengyu Zong, et al., bioRxiv - Physiology 2021

  Quote: ... (MCP-1) (R&D systems, 279-MC-050/CF). All chemicals for making Tyrode solution and recording solution (see U73122ow ...
• Robust three-dimensional expansion of human adult alveolar stem cells and SARS-CoV-2 infection

  Jeonghwan Youk, et al., bioRxiv - Cell Biology 2020

  Quote: ... rat anti-SCGB1A1 (1:200, R&D systems, MAB4218), rabbit anti-KRT5 (1:500 ...
• Deficiency of complement component C1Q prevents cerebrovascular damage and white matter loss in a mouse model of chronic obesity

  Leah C. Graham, et al., bioRxiv - Neuroscience 2020

  Quote: ... and goat anti-C3 (1:75, R&D systems). After primary antibodies incubation ...
• Molecular and genetic regulation of pig pancreatic islet cell development

  Seokho Kim, et al., bioRxiv - Developmental Biology 2020

  Quote: ... goat anti-PDX1 (R&D systems, AF2419, 1:200), mouse anti-human NKX6.1 (R&D systems ...
• The H2A.J histone variant contributes to Interferon-Stimulated Gene expression in senescence by its weak interaction with H1 and the derepression of repeated DNA sequences

  Adèle Mangelinck, et al., bioRxiv - Genetics 2020

  Quote: ... anti-IL6 (R&D Systems, AF-206, 1:200), anti-STAT1 (Invitrogen ...
• Notch signaling determines cell-fate specification of the two main types of vomeronasal neurons of rodents

  Raghu Ram Katreddi, et al., bioRxiv - Developmental Biology 2021

  Quote: ... *Goat anti-NeuroD1 (1:500, AF2746, R&D Systems), *Rabbit anti-Notch1 (1:50 ...
• Loss of Prdm12 during development, but not in mature nociceptors, causes defects in pain sensation

  Mark A. Landy, et al., bioRxiv - Neuroscience 2020

  Quote: ... goat anti-TRKA (1:20; R&D Systems AF1056), rabbit anti-RUNX3 (1:50,000 ...
• Time-resolved proteomic profiling of the ciliary Hedgehog response reveals that GPR161 and PKA undergo regulated co-exit from cilia

  Elena A. May, et al., bioRxiv - Cell Biology 2020

  Quote: ... anti-GLI3 (R&D Systems nachuryAF3690, goat 1:1,000) anti-actin (self-made ...
• Characterisation of the transcriptional dynamics underpinning the function, fate, and migration of the mouse Anterior Visceral Endoderm

  Shifaan Thowfeequ, et al., bioRxiv - Developmental Biology 2021

  Quote: ... 1:100 Goat anti-PlexinA1 (R&D Systems, AF4309), 1:200 Rabbit anti-Oct4 (Abcam ...
• Chromatin and gene-regulatory dynamics of the developing human cerebral cortex at single-cell resolution

  Alexandro E. Trevino, et al., bioRxiv - Neuroscience 2021

  Quote: ... anti-SOX9 (Goat, 1:500, R&D Systems, AF3075), anti-SPARCL1 (Goat ...
• Hyperoxia Inhibits the Growth of Mouse Forebrain Oligodendrocyte Progenitors

  Lisamarie Moore, et al., bioRxiv - Neuroscience 2021

  Quote: ... 1 ng/mL recombinant rat CNTF (R&D Systems) [29] ...
• Differentiation of human adult-derived stem cells towards a neural lineage involves a de-differentiation event prior to re-differentiation to neural phenotypes

  Carlos Bueno, et al., bioRxiv - Neuroscience 2021

  Quote: ... and IGF-1 (10□ng/ml; R&D systems). We perform time-lapse phase-contrast microscopy within the first 24 hr after neural induction media was added directly to the cells.
• Production and secretion of functional full-length SARS-CoV-2 spike protein in Chlamydomonas reinhardtii

  Anna Kiefer, et al., bioRxiv - Synthetic Biology 2021

  Quote: ... mouse anti-RBD (MAB105401, R&D Systems, 1:2,000) and mouse anti-ACE2 (sc-390851 ...
• DDR1-INDUCED NEUTROPHIL EXTRACELLULAR TRAPS DRIVE PANCREATIC CANCER METASTASIS

  Jenying Deng, et al., bioRxiv - Cancer Biology 2020

  Quote: ... or anti-myeloperoxidase (1:150 dilution; R&D Systems). After being washed with PBS ...
• JAG1 intracellular domain acts as a transcriptional cofactor that forms an oncogenic transcriptional complex with DDX17/SMAD3/TGIF2

  Eun-Jung Kim, et al., bioRxiv - Molecular Biology 2021

  Quote: ... anti-SOX2 (1:1000, Cat. #AF2018; R&D Systems), anti-DDX17 (1:1000 ...
• Neural plate targeting by in utero nanoinjection (NEPTUNE) reveals a role for Sptbn2 in neurulation and abdominal wall closure

  Katrin Mangold, et al., bioRxiv - Developmental Biology 2020

  Quote: ... goat-anti Olig1 (MAB2417, R&D systems 1:100); guinea pig anti-Dcx (AB2253 ...
• Zfp36l1 and Zfp36l2 balances proliferation and differentiation in the developing retina

  Fuguo Wu, et al., bioRxiv - Developmental Biology 2020

  Quote: ... goat anti-Nrl (R&D systems AF2945, 1:200), rabbit anti-Otx2 (Sigma B74059 ...
• Arap1 Loss Causes RPE Phagocytic Dysfunction and Subsequent Photoreceptor Death

  Andy Shao, et al., bioRxiv - Molecular Biology 2021

  Quote: ... and normal goat IgG (1:50, R&D Systems).
• The LUBAC participates in Lysophosphatidic Acid-induced NF-κB Activation

  Tiphaine Douanne, et al., bioRxiv - Immunology 2020

  Quote: ... or with 10 ng.mL−1 TNFα (R&D Systems). The protease activity of MALT1 was blocked with 20 μM of Mepazine (Chembridge) ...
• Identifying dysregulated immune cell subsets following critical volumetric muscle loss with pseudo-time trajectories

  Lauren A. Hymel, et al., bioRxiv - Immunology 2021

  Quote: ... and PE-conjugated anti-SDF-1 (R&D Systems). 30μL of CountBright Absolute Counting Beads (C36950 ...
• A secreted proteomic footprint for stem cell pluripotency

  Philip Lewis, et al., bioRxiv - Cell Biology 2021

  Quote: ... 1/500 mouse anti-FGFR1 (R&D systems, MAB658); 1/1000 rabbit anti-Follistatin (Abcam ...
• Self-organized stem cell-derived human lung buds with proximo-distal patterning and novel targets of SARS-CoV-2

  E.A. Rosado-Olivieri, et al., bioRxiv - Developmental Biology 2021

  Quote: ... goat anti-TP63 (R&D Systems; BAF1916; 1:250), rabbit anti-proSPC (Seven Hills ...
• Type I IFN signaling mediates NET release to promote Mycobacterium tuberculosis replication and granuloma caseation

  Chanchal Sur Chowdhury, et al., bioRxiv - Microbiology 2022

  Quote: ... myeloperoxidase (MPO, goat polyclonal R&D Systems, 1:200) or Ly6G (Clone 1A8 ...
• Self-organization, quality control, and preclinical studies of human iPSC-derived retinal sheets for tissue-transplantation therapy

  Kenji Watari, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-human Ku80 (goat; 1:500; R&D Systems), anti-Gnat1 (rabbit ...
• MOPD I patient-derived cerebral organoids model microcephaly showing premature neurogenesis due to disrupted mitotic spindle orientation

  Jagjit Singh, et al., bioRxiv - Neuroscience 2022

  Quote: ... Primary antibody [(SOX1, R&D Systems, #AF3369, 1:100), (TBR2 ...
• High resolution photocatalytic mapping of SARS-CoV-2 Spike protein-host cell membrane interactions

  Suprama Datta, et al., bioRxiv - Biochemistry 2022

  Quote: ... Anti-PTGFRN antibody (R&D Systems: MAB100431; 1:1000), anti-EFNB1 antibody (Invitrogen ...
• FGF2 and BMP4 influence on FGFR2 dynamics during the segregation of epiblast and primitive endoderm cells in the pre-implantation mouse embryo

  Marcelo D. Goissis, et al., bioRxiv - Developmental Biology 2022

  Quote: ... goat anti-GATA6 (R&D Systems, AF1700, 1:40) or goat anti-SOX17 (R&D Systems ...
• RBM43 links adipose inflammation and energy expenditure through translational regulation of PGC1α

  Phillip A. Dumesic, et al., bioRxiv - Cell Biology 2023

  Quote: ... IL-1β (25 ng ml-1, R&D Systems), LPS (100 ng ml-1 ...
• Partial in vivo reprogramming enables injury-free intestinal regeneration via autonomous Ptgs1 induction

  Jumee Kim, et al., bioRxiv - Cell Biology 2023

  Quote: ... goat anti-Trop2 (R&D Systems, AF1122, 1:100), mouse anti-Cox1 (Santa cruz ...
• Multiple cancer types rapidly escape from multiple MAPK inhibitors to generate mutagenesis-prone subpopulations

  Timothy E. Hoffman, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Ki67 sheep pAb (1:200, R&D Systems #AF7617). Secondary antibodies in this study include goat anti-rabbit ...
• Sex-dependent improvement in traumatic brain injury outcomes after liposomal delivery of dexamethasone in mice

  Gherardo Baudo, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-rat F4/80 (1:200, R&D Systems) for infiltrated macrophages ...
• Neuroprotective effects of hepatoma-derived growth factor in models of Huntington’s disease

  Kerstin Voelkl, et al., bioRxiv - Neuroscience 2023

  Quote: ... mouse anti-NGRN (R&D Systems, MAB7947, 1:60), chicken anti-GFAP (Origene ...
• Illuminating the Terminal Nerve: Uncovering the Link between GnRH-1 and Olfactory Development

  Enrico Amato Jr, et al., bioRxiv - Developmental Biology 2023

  Quote: ... goat-α-AP-2χ (1:500, R&D Systems), rabbit-α-Meis2 (1:1000 ...
• Inhibition of CPEB3 ribozyme elevates CPEB3 protein expression and polyadenylation of its target mRNAs, and enhances object location memory

  Claire C. Chen, et al., bioRxiv - Neuroscience 2023

  Quote: ... goat anti-mouse-HRP (R&D system, 1:1000).
• Molecular characterization of nodose ganglia development reveals a novel population of Phox2b+ glial progenitors in mice

  Elijah D. Lowenstein, et al., bioRxiv - Neuroscience 2023

  Quote: ... goat anti-Phox2b (R&D Systems, AF4940, 1:200), rabbit anti-Sox10 (Abcam ...
• A combination of convergent extension and differential adhesion explains the shapes of elongating gastruloids

  Martijn A. de Jong, et al., bioRxiv - Developmental Biology 2023

  Quote: ... goat anti-T (1:200, AF2085, R&D Systems) and rat anti-Cerberus1 (1:200 ...
• A combination of convergent extension and differential adhesion explains the shapes of elongating gastruloids

  Martijn A. de Jong, et al., bioRxiv - Developmental Biology 2023

  Quote: ... goat anti-T (1:200, AF2085, R&D Systems) and rabbit anti-KI-67 (1:200 ...
• Krause corpuscles of the genitalia are vibrotactile sensors required for normal sexual behavior

  Lijun Qi, et al., bioRxiv - Neuroscience 2023

  Quote: ... goat anti-CD31 (R&D Systems, AF3628, 1:500), guinea pig anti-FLAG (1:500 ...
• Ciliary ARL13B prevents obesity in mice

  Tiffany T. Terry, et al., bioRxiv - Genetics 2023

  Quote: ... rat anti-insulin (1:1000, R&D systems, MAB1417); rabbit anti-glucagon (1:2000 ...
• A Dual Color Pax7 and Myf5 In Vivo Reporter to Investigate Muscle Stem Cell Heterogeneity in Regeneration and Aging

  Sara Ancel, et al., bioRxiv - Cell Biology 2023

  Quote: ... and α7-integrin (R&D Systems, #FAB3518N, 1/30). Myf5 subpopulations identified as Pax7-ZsGreen1 positive and Myf5-E2Crimson high or low were isolated using a Beckman Coulter Astrios Cell sorter.
• A collaboration between immune cells and the choroid plexus epithelium in brain inflammation

  Huixin Xu, et al., bioRxiv - Neuroscience 2023

  Quote: ... goat anti-S100A9 (R&D Systems AF2065, 1:200), rabbit anti-Occludin (ThermoFisher 71-1500 ...
• Genetic dissection of BDNF and TrkB expression in glial cells

  Changran Niu, et al., bioRxiv - Neuroscience 2023

  Quote: ... goat anti-SOX9 (1:2000; R&D Systems #AF3075), mouse anti-GFAP (1:500 ...