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2201 - 2250 of 10000+ citations for 7 Amino 1 3 dimethyl 1H 8H pyrido 2 3 d pyrimidine 2 4 5 trione since 2020

• Cytosolic S100A8/A9 promotes Ca²⁺ supply at LFA-1 adhesion clusters during neutrophil recruitment

  Matteo Napoli, et al., bioRxiv - Physiology 2024

  Quote: ... CXCR2-APC (5μg mL-1; 242216; R&D Systems), CD44-BV570 (0.3μg mL-1 ...
• Molecular and spatial analysis of ganglion cells on retinal flatmounts: diversity, topography, and perivascularity

  Nicole Y. Tsai, et al., bioRxiv - Neuroscience 2024

  Quote: ... goat anti-Osteopontin/Spp1 (1:500, R&D Systems); mouse anti-Tuj1 (1:1000 ...
• Cell surface ribonucleoproteins cluster with heparan sulfate to regulate growth factor signaling

  Peiyuan Chai, et al., bioRxiv - Molecular Biology 2024

  Quote: ... and 1 µg/mL anti-VEGFR2 (R&D Systems) were precomplexed with 0.5 µg/mL of goat anti-Rabbit AF647 secondary antibody and donkey anti-Goat AF647 secondary antibody (ThermoFisher Scientific) ...
• Afadin-deficient retinas exhibit severe neuronal lamination defects but preserve visual functions

  Akiko Ueno, et al., bioRxiv - Neuroscience 2024

  Quote: ... anti-Otx2 (AF1979, R&D systems, USA, 1:200), anti-Glutamine synthetase (GS ...
• Afadin-deficient retinas exhibit severe neuronal lamination defects but preserve visual functions

  Akiko Ueno, et al., bioRxiv - Neuroscience 2024

  Quote: ... anti-SCGN (AF4878, R&D systems, USA, 1:2000), anti-Arr3 (AB15282 ...
• The neurovascular coupling response of the aged brain is brain-state dependent.

  Xiao zhang, et al., bioRxiv - Neuroscience 2024

  Quote: ... goat anti PDGFRβ (1:250, AF1042, R&D Systems), mouse anti αSMA-FITC (1:200 ...
• Differential contribution of P73⁺ Cajal-Retzius cells and Reelin to cortical morphogenesis

  Vicente Elorriaga, et al., bioRxiv - Neuroscience 2024

  Quote: ... goat anti-Reelin (R&D Systems AF3820 1:2000), rabbit anti-TBR1 (Abcam ab31940 1:1000).
• Oxygen-induced stress reveals context-specific gene regulatory effects in human brain organoids

  Benjamin D. Umans, Yoav Gilad, bioRxiv - Genomics 2024

  Quote: ... N21 without vitamin A (1%, R&D Systems AR012), insulin (2 µg/mL ...
• Cholinergic Neuronal Activity Promotes Diffuse Midline Glioma Growth through Muscarinic Signaling

  Richard Drexler, et al., bioRxiv - Neuroscience 2024

  Quote: ... goat anti-Pdgfra (1:500; R&D Systems, AF1062), rat anti-MBP (1:200 ...
• Cytokine-induced reprogramming of human macrophages toward Alzheimer’s disease-relevant molecular and cellular phenotypes in vitro

  Anna Podlesny-Drabiniok, et al., bioRxiv - Immunology 2024

  Quote: ... CXCR4-APC 1:100 (R&D Systems, cat. FAB172R), CD44-APC 1:100 (BioLegend ...
• The transcriptomic landscape of spinal V1 interneurons reveals a role for En1 in specific elements of motor output

  Alexandra J. Trevisan, et al., bioRxiv - Neuroscience 2024

  Quote: ... sheep anti-Oc2 (1:2000, R&D Systems #AF6294); guinea pig anti-Otp (1:16000 ...
• Enhancing oncolytic virotherapy by exosome-mediated microRNA reprograming of the tumour microenvironment

  Victoria A. Jennings, et al., bioRxiv - Cancer Biology 2024

  Quote: ... mouse and human Arginase-1-FITC (R&D systems), PD-L1-FITC (MIH1) ...
• The chromatin remodeler CHD3 is highly expressed in mature neurons and regulates genes involved in synaptic development and function

  Joery den Hoed, et al., bioRxiv - Neuroscience 2024

  Quote: ... goat-anti-SOX2 (1:500, af2018, R&D systems); mouse anti-TRA-1-60 (1:200 ...
• Abnormal morphology and synaptogenic signaling in astrocytes following prenatal opioid exposure

  Ethan B. Niebergall, et al., bioRxiv - Neuroscience 2024

  Quote: ... goat anti-Tsp1 (1:1000; R&D Systems AF3074), goat anti-Tsp2 (1:1000 ...
• Gpr37 modulates the severity of inflammation-induced GI dysmotility by regulating enteric reactive gliosis

  Keiramarie Robertson, et al., bioRxiv - Neuroscience 2024

  Quote: ... goat anti-Sox10 (1:500; R&D Systems, AF2864), human anti-HuC/D (ANNA1 ...
• Abnormal morphology and synaptogenic signaling in astrocytes following prenatal opioid exposure

  Ethan B. Niebergall, et al., bioRxiv - Neuroscience 2024

  Quote: ... goat anti-Tsp4 (1:1000; R&D Systems AF2390). The next day ...
• Abnormal morphology and synaptogenic signaling in astrocytes following prenatal opioid exposure

  Ethan B. Niebergall, et al., bioRxiv - Neuroscience 2024

  Quote: ... mouse anti-SPARC (1:1000; R&D Systems AF942), goat anti-Tsp1 (1:1000 ...
• Abnormal morphology and synaptogenic signaling in astrocytes following prenatal opioid exposure

  Ethan B. Niebergall, et al., bioRxiv - Neuroscience 2024

  Quote: ... goat anti-Tsp2 (1:1000; R&D Systems AF1635), goat anti-Tsp4 (1:1000 ...
• Antibiotic treatment induces microbiome dysbiosis and reduction of neuroinflammation following traumatic brain injury in mice

  Hannah Flinn, et al., bioRxiv - Neuroscience 2024

  Quote: ... anti-rat F4/80 (1:200, R&D Systems), anti-rabbit P2Y12 (1:500 ...
• Abnormal morphology and synaptogenic signaling in astrocytes following prenatal opioid exposure

  Ethan B. Niebergall, et al., bioRxiv - Neuroscience 2024

  Quote: ... mouse anti-Hevin (1:2000; R&D Systems AF2836), mouse anti-SPARC (1:1000 ...
• MEK1/2 and ERK1/2 mediated lung endothelial injury and altered hemostasis promote diffuse alveolar hemorrhage in murine lupus

  Haoyang Zhuang, et al., bioRxiv - Immunology 2024

  Quote: ... anti-CD31/Pecam1 (R&D Systems 1:200, Dako), and F4/80 (1:200 ...
• Trehalose-based coacervates for local bioactive protein delivery to the central nervous system

  Laboni F Hassan, Riya Sen, Timothy M O’Shea, bioRxiv - Bioengineering 2024

  Quote: ... anti-Goat Cd13 (R&D systems, AF2335, 1:500); anti-Rat Ly6b2 (BioRad ...
• Thrombolysis exacerbates cerebrovascular injury after ischemic stroke via a VEGF-B dependent effect on adipose lipolysis

  Ingrid Nilsson, et al., bioRxiv - Neuroscience 2024

  Quote: ... goat anti-podocalyxin (1:200, AF1556; R&D Systems) and goat anti-VEGFR1 (1:200 ...
• Thrombolysis exacerbates cerebrovascular injury after ischemic stroke via a VEGF-B dependent effect on adipose lipolysis

  Ingrid Nilsson, et al., bioRxiv - Neuroscience 2024

  Quote: ... goat anti-CD31 (1:200, AF3628; R&D Systems), rabbit anti-claudin-5 (1:200 ...
• Differential contribution of P73⁺ Cajal-Retzius cells and Reelin to cortical morphogenesis

  Vicente Elorriaga, et al., bioRxiv - Neuroscience 2024

  Quote: ... goat anti-Prox1 (R&D Systems AF2727 1:1000), goat anti-Reelin (R&D Systems AF3820 1:2000) ...
• Mechanosensitive PIEZO2 channels shape coronary artery development

  Mireia Pampols-Perez, et al., bioRxiv - Developmental Biology 2024

  Quote: ... goat anti-SOX17 (1:100, AF1924, R&D Systems), rabbit anti-RFP (1:1000 ...
• Arterial endothelial deletion of hereditary hemorrhagic telangiectasia 2/Alk1 causes epistaxis and cerebral microhemorrhage with aberrant arteries and defective smooth muscle coverage

  Xuetao Zhang, et al., bioRxiv - Pathology 2024

  Quote: ... goat anti-ALK1 (R&D Systems, 1:200 dilution), (6 ...
• FBXW7 regulates MYRF levels to control myelin capacity and homeostasis in the adult CNS

  Hannah Y. Collins, et al., bioRxiv - Neuroscience 2024

  Quote: ... goat anti-PDGFRα (1:500; AF1062, R&D Systems), rabbit anti-Iba1 (1:1000 ...
• The Alzheimer’s Disease Risk Genes MS4A4A And MS4A6A Cooperate to Negatively Regulate Trem2 and Microglia states

  Dalya Rosner, et al., bioRxiv - Neuroscience 2024

  Quote: ... or TREM2 (1:1,000 dilution, R&D Systems #BAF1828) overnight at 4°C ...
• Buprenorphine Induces Human Fetal Membrane Sterile Inflammation

  Tatyana Lynn, et al., bioRxiv - Immunology 2024

  Quote: ... and CCL2/MCP-1 (R&D Systems, Minneapolis, MN). All assays were run in duplicate.
• Systematic identification of Y-chromosome gene functions in mouse spermatogenesis

  Jeremie Subrini, et al., bioRxiv - Genetics 2024

  Quote: ... and goat cKIT (1:100, AF1356, R&D systems) at 4°C overnight ...
• Glutamatergic regulation of miRNA-containing exosome precursor trafficking and secretion from cortical neurons

  Marcela Bertolio, et al., bioRxiv - Neuroscience 2024

  Quote: ... and βIII-tubulin (1:1000, R&D Systems #MAB1195) were incubated overnight at 4 °C in blocking buffer ...
• Engineered human iPS cell models reveal altered podocytogenesis and glomerular capillary wall in CHD-associated SMAD2 mutations

  Rohan Bhattacharya, et al., bioRxiv - Bioengineering 2024

  Quote: ... goat Anti-Goosecoid (R&D Systems, AF4086, 1:250), mouse Anti-Twist antibody (Abcam ...
• Engineered human iPS cell models reveal altered podocytogenesis and glomerular capillary wall in CHD-associated SMAD2 mutations

  Rohan Bhattacharya, et al., bioRxiv - Bioengineering 2024

  Quote: ... goat Anti-Goosecoid (R&D Systems, AF4086, 1:500), rabbit Anti-PAX2 (Cell Signaling ...
• The temporal refinement of Dach1 is a key step in the functional maturation of primary somatosensory neurons

  Tünde Szemes, et al., bioRxiv - Neuroscience 2024

  Quote: ... goat anti-TrkA (1:500, R&D System, AF761), guinea pig anti-Parvalbumin (1:500 ...
• The temporal refinement of Dach1 is a key step in the functional maturation of primary somatosensory neurons

  Tünde Szemes, et al., bioRxiv - Neuroscience 2024

  Quote: ... goat anti-Ret (1:50, R&D systems, AF482), goat anti-calcitonin gene related peptide (CGRP ...
• The temporal refinement of Dach1 is a key step in the functional maturation of primary somatosensory neurons

  Tünde Szemes, et al., bioRxiv - Neuroscience 2024

  Quote: ... goat anti-TrkC (1:500, R&D System, AF1404), goat anti-TrkA (1:500 ...
• The temporal refinement of Dach1 is a key step in the functional maturation of primary somatosensory neurons

  Tünde Szemes, et al., bioRxiv - Neuroscience 2024

  Quote: ... goat anti-TrkB (1:500, R&D System, AF1494), goat anti-TrkC (1:500 ...
• Morphogenetic constrains in the development of gastruloids: implications for mouse gastrulation

  U.M. Fiuza, et al., bioRxiv - Developmental Biology 2024

  Quote: ... goat anti-Tbx6 (AF4744; R&D Systems; 1:200), rabbit anti-PhosphoMyosin Light Chain 2 (Ser19 ...
• Optimizing PSC culture for generating neural organoids

  Magdalena A. Sutcliffe, et al., bioRxiv - Cell Biology 2024

  Quote: ... TBR2 (R&D Systems, AF6166 1:200 for IF), HuC/D (Invitrogen ...
• Mechanical stretch induced collective cell alignment

  Xuechen Shi, Sulin Zhang, bioRxiv - Bioengineering 2024

  Quote: ... and 1% (v/v) penicillin-streptomycin (R&D Systems). Cells at passage numbers 10-13 were used in the experiments ...
• Spatiotemporal coordination of actin regulators generates invasive protrusions in cell-cell fusion

  Yue Lu, et al., bioRxiv - Cell Biology 2024

  Quote: ... sheep anti-ESGP (1:1000; R&D Systems; AF4580), mouse anti-α-actin (1:50000 ...
• Depolymerizing F-actin accelerates the exit from pluripotency to enhance stem cell-derived islet differentiation

  Nathaniel J. Hogrebe, et al., bioRxiv - Cell Biology 2024

  Quote: ... 1:300 goat anti-PDX1 (AF2419, R&D Systems), 1:1,000 rabbit anti-CHGA (ab15160 ...
• Depolymerizing F-actin accelerates the exit from pluripotency to enhance stem cell-derived islet differentiation

  Nathaniel J. Hogrebe, et al., bioRxiv - Cell Biology 2024

  Quote: ... 1:300 goat anti-PDX1 (AF2419, R&D Systems), 1:500 mouse anti-OTX2 (NBP2-37597 ...
• C-C chemokine receptor 4 deficiency exacerbates early atherosclerosis in mice

  Toru Tanaka, et al., bioRxiv - Immunology 2024

  Quote: ... or goat anti-CCL22 (1:200; R&D Systems) antibodies ...
• Epigenetic restoration of differentiation competency via reversal of epiblast regionalisation

  Magdalena A. Sutcliffe, et al., bioRxiv - Developmental Biology 2024

  Quote: ... SOX10 (R&D Systems, AF2864, 1:500 for IF), SOX17 (R&D Systems ...
• A PRDM16-CtBP1/2 Complex Interacts with HDAC1/2 to Regulate Transcriptional Programs of Neurogenesis and Guide Cortical Neuron Migration

  Sophie Warren, et al., bioRxiv - Developmental Biology 2024

  Quote: ... and anti-Nestin (R&D Systems, MAB2736, 1:500). To detect primary antibodies ...
• The transcription factor GABPA is a master regulator of naïve pluripotency

  Chengjie Zhou, Meng Wang, Chunxia Zhang, Yi Zhang, bioRxiv - Developmental Biology 2024

  Quote: ... anti-GATA4 (1:200, R&D Systems, MAB2606-SP), anti-NANOG (1:200 ...
• Epigenetic restoration of differentiation competency via reversal of epiblast regionalisation

  Magdalena A. Sutcliffe, et al., bioRxiv - Developmental Biology 2024

  Quote: ... SOX17 (R&D Systems, AF1924 1:200 for IF), CDX2 (Cell Signalling Technology ...
• SCA-1 micro-heterogeneity in the fate decision of dystrophic fibro/adipogenic progenitors

  Giulio Giuliani, et al., bioRxiv - Cell Biology 2020

  Quote: ... cells were incubated over night at 4 °C with the anti-CD140a (R&D Systems AF1062) diluted 1:80 in blocking solution ...