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401 - 450 of 8417 citations for 2 Chloro 1 1 trifluoromethyl 1 3 4 9 tetrahydro 2H beta carbolin 2 yl ethan 1 one since 2020

• Morphogen-driven human iPSCs differentiation in 3D in vitro models of gastrulation is precluded by physical confinement

  Haneen S. Alsehli, et al., bioRxiv - Cell Biology 2023

  Quote: ... goat anti-SOX17 (R&D, 1:50) were diluted and YAP 1 (Santa Cruz, 1:50) were diluted in the blocking buffer and incubated for 48 h in the dark at 4°C on a shaker ...
• Reduction of DNA Topoisomerase Top2 reprograms the epigenetic landscape and extends health and life span across species

  Man Zhu, et al., bioRxiv - Biochemistry 2024

  Quote: ... Poly (ADP-ribose) polymerase-1 (PARP-1, 1:1000; Catalog# sc-8007; SANTA CRUZ BIOTECHNOLOGY, INC.), TFEB (1:3000 ...
• Steroid hormone catabolites activate the pyrin inflammasome through a non-canonical mechanism

  Flora Magnotti, et al., bioRxiv - Immunology 2021

  Quote: ... cells were stained using anti-ASC (Santa Cruz, sc22514R, 4 μg.mL-1), Alexa594-goat anti rabbit antibodies (Invitrogen ...
• Protein kinase Cε activation induces EHD-dependent degradation and downregulation of K_ATP channels: Implications for glucose stimulated insulin secretion

  Christopher J Cockcroft, et al., bioRxiv - Cell Biology 2020

  Quote: ... or mouse anti-Rme-1-4 (Santa Cruz Biotechnology, EHD (E-5), 0.8 μg/ml ...
• Role of ERK activation in H. pylori-induced disruption of cell-cell tight junctions

  Amita Sekar, Bow Ho, bioRxiv - Microbiology 2020

  Quote: ... and rabbit polyclonal anti-claudin-4 (1:1000, Santa Cruz Biotechnology, USA) were used in immunofluorescence and immunoblotting experiments respectively ...
• Prostaglandin E₂ controls the metabolic adaptation of T cells to the intestinal microenvironment

  Matteo Villa, et al., bioRxiv - Immunology 2023

  Quote: ... anti-EP4 (encoded by Ptger4, clone C-4, 1:100, Santa Cruz), anti-ATG5 (clone D5F5U ...
• Mechanisms of insertions at a DNA double-strand break

  Jaewon Min, et al., bioRxiv - Molecular Biology 2022

  Quote: ... anti-β-Actin (1:1000; C-4, Santa Cruz Biotechnology, sc-47778). anti-rabbit immunoglobulin G (IgG ...
• rRNA Biogenesis Regulates Mouse 2C-like State by 3D Structure Reorganization of Peri-Nucleolar Heterochromatin

  Hua Yu, et al., bioRxiv - Cell Biology 2021

  Quote: ... followed by incubation overnight with primary antibodies (1:200, Nucleolin, CST, 145745; 1:400, NPM1, Sigma, B0556; 1:200, Fibrillarin, Abcam, ab4566; RPA194, 1:50, Santa Cruz, sc-48385) at 4 degree or for 1hr at 37 °C ...
• rRNA Biogenesis Regulates Mouse 2C-like State by 3D Structure Reorganization of Peri-Nucleolar Heterochromatin

  Hua Yu, et al., bioRxiv - Cell Biology 2021

  Quote: ... for 10 min at RT and then stained with a primary antibody (1:200, Nucleolin, CST, 145745; 1:400, NPM1, Sigma, B0556; 1:200, Fibrillarin, Abcam, ab4566; RPA194, 1:50, Santa Cruz, sc-48385) for 12 h at 4 °C ...
• Neurogenin 2 and Neuronal Differentiation 1 control proper development of the chick trigeminal ganglion and its nerve branches

  Parinaz Bina, Lisa A. Taneyhill, bioRxiv - Developmental Biology 2022

  Quote: ... for 15 minutes at 37°C and re-probed with a loading control antibody (anti-Beta-actin primary antibody (1:1,500, Santa Cruz Biotechnology ...
• RUNX1 mitotically bookmarks target genes that are important for the mammary epithelial-to-mesenchymal transition

  Joshua T. Rose, et al., bioRxiv - Cancer Biology 2020

  Quote: ... and Upstream Binding Transcription Factor (UBF) at 1:200 dilution (F-9 sc-13125, Santa Cruz Biotechnology, Dallas, TX). Secondary antibodies used were goat anti-rabbit IgG conjugated with Alexa Fluor 488 (A-11070 ...
• Clinically defined mutations in MEN1 alter its tumor-suppressive function through increased menin turnover

  Suzann Duan, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Mouse anti-Menin monoclonal antibody (1:2,000 dilution, Cat #sc-374371, Clone B-9, RRID: AB_10987907, Santa Cruz Biotechnology), Rabbit anti-Menin polyclonal (1:10,000 dilution ...
• Analysis of alternative mRNA splicing in vemurafenib-resistant melanoma cells

  Honey Bokharaie, Walter Kolch, Aleksandar Krstic, bioRxiv - Cancer Biology 2022

  Quote: ... SF3B1 / SAP 155 (B-3) (1/1000 dilution, #sc-514655, Santa Cruz, Mouse), HSP90 (c45g5 ...
• Inter-domain dynamics drive cholesterol transport by NPC1 and NPC1L1 proteins

  Piyali Saha, et al., bioRxiv - Biochemistry 2020

  Quote: ... Ezetimibe and lysophosphatidylcholine (1-palmitoyl-sn-glycero-3-phosphocholine) were from Santa Cruz Biotechnology (Santa Cruz ...
• Inhibition of OCT4 Binding at the MYCN Locus Induces Neuroblastoma Cell Death Accompanied by Downregulation of Transcripts with High-Open Reading Frame Dominance

  Kazuma Nakatani, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-caspase 3 (1:1000 dilution; sc-7148, Santa Cruz Biotechnology, Dallas, TX), and anti-actin (1:1000 dilution ...
• Direct interaction with the BRD4 carboxyl-terminal motif (CTM) and TopBP1 is required for human papillomavirus 16 E2 association with mitotic chromatin and plasmid segregation function

  Apurva T. Prabhakar, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) 1:10,000 (Santa Cruz; catalog no. sc-47724).
• RSV protects bystander cells against IAV infection by triggering secretion of type I and type III interferons

  Maciej Czerkies, et al., bioRxiv - Immunology 2022

  Quote: ... anti-OAS1 Antibody (F-3) (Santa Cruz Biotechnology, cat. sc-374656, 1:1000), anti-Influenza A Virus Nucleoprotein antibody [C43] (Abcam ...
• Development of allosteric, selective cyclin-dependent kinase 2 (CDK2) inhibitors that are negatively cooperative with cyclin binding and show potential as contraceptive agents

  Erik B. Faber, et al., bioRxiv - Pharmacology and Toxicology 2022

  Quote: ... and anti-SYCP-3 monoclonal antibody (sc-74569, Santa Cruz Biotechnology, 1:100) overnight at 4 °C ...
• pVHL regulates protein stability of TCF/LEF transcription factor family via ubiquitin-independent proteasomal degradation

  Caixia Wang, et al., bioRxiv - Cell Biology 2021

  Quote: ... mouse anti-Myc (1:1,000 for western blotting and 2 μg for co-IP assays; sc-40; Santa Cruz Biotechnology), and mouse anti-Flag (1:1,000 for western blotting and 2 μg for co-IP assays ...
• Subcellular dynamics and functional activity of the cleaved Na⁺ channel β1 subunit intracellular domain

  Alexander S. Haworth, et al., bioRxiv - Cell Biology 2021

  Quote: ... N-[(3,5-Difluorophenyl)acetyl]-L-alanyl-2-phenyl]glycine-1,1-dimethylethyl ester (DAPT) (1 μM, 24 h, Santa Cruz Biotech) and L-685,458 (1 - 10 μM ...
• Spatially resolved DNP-assisted NMR illuminates the conformational ensemble of α-synuclein in intact viable cells

  Jaka Kragelj, et al., bioRxiv - Biophysics 2023

  Quote: ... Cells were then incubated for 2 h with primary antibody anti-α-Syn sc-69977 (Santa Cruz, 1:100 dilution) in blocking buffer ...
• Pseudokinase HPO-11 inhibits nonsense-mediated decay to ensure genome stability in C. elegans

  Qian Zhao, et al., bioRxiv - Molecular Biology 2022

  Quote: ... Antibodies for IP (NRBP1/2 rabbit, 21549-1-AP –ptg) and mock IP (IgG rabbit, Santa Cruz Biotech, sc-2027) were then added into the supernatant ...
• Deamidated TPI is an efficacious target for cell-selective therapy in triple-negative breast cancer

  Sergio Enríquez-Flores, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Bax (B-9) and β-Actin (C-2) (Santa Cruz Biotechnology, Santa Cruz, CA, USA) at a dilution of 1:1000 in 0.1% TBS-Tween-20 and 1% BSA and washed three times with the same buffer ...
• Deamidated TPI is an efficacious target for cell-selective therapy in triple-negative breast cancer

  Sergio Enríquez-Flores, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Bax (B-9) and β-Actin (C-2) (Santa Cruz Biotechnology, Santa Cruz, CA, USA) at a dilution of 1:1000 in 0.1% TBS-Tween-20 and 1% BSA and washed three times with the same buffer ...
• Syndecan-4^-/- mice have smaller muscle fibers, increased Akt/mTOR/S6K1 and Notch/HES-1 pathways, and alterations in extracellular matrix components

  Sissel Beate Rønning, et al., bioRxiv - Cell Biology 2020

  Quote: ... anti-fibromodulin (1:500, 1% casein, sc-33772, Santa Cruz), anti-pSer2448-mTOR (1:1000 ...
• Steroid hormone catabolites activate the pyrin inflammasome through a non-canonical mechanism

  Flora Magnotti, et al., bioRxiv - Immunology 2021

  Quote: ... anti-human Caspase-1 (Santa Cruz, sc515, 1: 1,000 dilution), anti-human GSGMD (sigma ...
• RhoA- and Ran-induced antagonistic forces underlie symmetry breaking and spindle rotation in mouse oocytes

  Benoit Dehapiot, et al., bioRxiv - Developmental Biology 2020

  Quote: ... Rock-1 (1/100, Goat polyclonal; Santa Cruz sc-6056). Secondary antibodies were Alexa Fluor 488-conjugated donkey anti-goat ...
• CDK5 influences the organization of the Circadian Machinery in peripheral clocks

  Jürgen Ripperger, Urs Albrecht, Andrea Brenna, bioRxiv - Molecular Biology 2021

  Quote: ... while Tubulin by Abcam (1:1000) and Lamin B by Santa Cruz (1:1000). The day after ...
• GPCR-mediated clearance of tau in post-synaptic compartments attenuates tau pathology in vivo

  Ari W. Schaler, et al., bioRxiv - Neuroscience 2020

  Quote: ... CamKIIα (1:2000, A-1, sc13141) was from Santa Cruz Biotechnology ...
• Phenomenon of music-induced opening of the blood-brain barrier in healthy mice

  O. Semyachkina-Glushkovskaya, et al., bioRxiv - Neuroscience 2020

  Quote: ... ZO-1 (1:500; Santa Cruz Biotechnology, Santa Cruz, USA), OCC and NG2 (1:500 ...
• Phenomenon of music-induced opening of the blood-brain barrier in healthy mice

  O. Semyachkina-Glushkovskaya, et al., bioRxiv - Neuroscience 2020

  Quote: ... ZO-1 (1:500; Santa Cruz Biotechnology, Santa Cruz, USA), OCC and NG2 (1:500 ...
• Klebsiella pneumoniae reduces SUMOylation to limit host defence responses

  Joana Sá-Pessoa, et al., bioRxiv - Microbiology 2020

  Quote: ... anti-Cullin-1 (1:200, Santa Cruz Biotechnology sc-12761), anti-Flag M2 (1 μg ...
• Modelling TGFβR and Hh pathway regulation of prognostic matrisome molecules in ovarian cancer

  Robin M. Delaine-Smith, et al., bioRxiv - Cancer Biology 2021

  Quote: ... GLI-1 Antibody (C-1, sc-515751) from Santa Cruz Biotechnology.
• Reliance of neuronal gene expression on cohesin scales with chromatin loop length

  Lesly Calderon, et al., bioRxiv - Genomics 2022

  Quote: ... CUX-1 (1:400; rabbit polyclonal sc-13024, Santa Cruz) and anti phospho-histone H3 (Ser10 ...
• The phospho-regulated amphiphysin/endophilin interaction is required for synaptic vesicle endocytosis

  Christiana Kontaxi, Michael A. Cousin, bioRxiv - Neuroscience 2023

  Quote: ... goat syndapin 1 (1:1000; Santa Cruz Biotechnology, sc-10412), and mouse PSD95 (1:1000 ...
• Mice with renal-specific alterations of stem cell-associated signaling develop symptoms of chronic kidney disease but surprisingly no tumors

  Adam Myszczyszyn, et al., bioRxiv - Cell Biology 2023

  Quote: ... rat anti-Zo-1 (1:200, Santa Cruz, sc-33725), mouse anti-MDR1 (1:50 ...
• Multiomic Approach Characterises the Neuroprotective Role of Retromer in Regulating Lysosomal Health

  James L. Daly, et al., bioRxiv - Neuroscience 2022

  Quote: ... VPS29 (Santa Cruz; D-1; sc-398874; 1:500 WB), VPS35 (Abcam ...
• Vitamin C is an efficient natural product for prevention of SARS-CoV-2 infection by targeting ACE2 in both cell and in vivo mouse models

  Yibo Zuo, et al., bioRxiv - Microbiology 2022

  Quote: ... anti-Ubiquitin (Ub) (Santa Cruz, 12987-1-AP, 1:1000), anti-K48 Ub (Cell Signaling Technology ...
• A postnatal molecular switch drives the activity-dependent maturation of parvalbumin interneurons

  Monika Moissidis, et al., bioRxiv - Neuroscience 2024

  Quote: ... mouse anti-PGC-1⍺ (1:200, Santa Cruz #sc-518025), mouse anti-Kv1.1 (1:1,000 ...
• Nsp1 proteins of human coronaviruses HCoV-OC43 and SARS-CoV2 inhibit stress granule formation

  Stacia M. Dolliver, et al., bioRxiv - Microbiology 2022

  Quote: ... TIA-1 (1:200; goat, Santa Cruz Biotechnology, sc-1751); TIAR (1:1000 ...
• A chemical probe to modulate human GID4 Pro/N-degron interactions

  Dominic D.G Owens, et al., bioRxiv - Molecular Biology 2023

  Quote: ... ARMC8 (E-1, sc-365307; Santa Cruz Biotechnology, 1:500), WDR26 (ab85962 ...
• The large GTPase Guanylate-Binding Protein-1 (GBP-1) promotes mitochondrial fission in glioblastoma

  Ryan C. Kalb, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Anti-GBP-1 (1b1) (1:25; Calbiochem or Santa Cruz), anti-myc (1:50 ...
• A comprehensive genetic catalog of human double-strand break repair

  Ernesto López de Alba, et al., bioRxiv - Molecular Biology 2024

  Quote: ... PCNA (1:1000, TBST 1% BSA, Santa Cruz sc-56).
• Vascular FLRT2 regulates venous-mediated angiogenic expansion and CNS barriergenesis

  C. Llaó-Cid, et al., bioRxiv - Neuroscience 2024

  Quote: ... mouse anti-Numb 1 1:1000 (sc-136554, Santa Cruz), rabbit anti-β-catenin 1:2000 (8480 ...
• GlycoRNA-L and glycoRNA-S mediate human monocyte adhesion via binding to Siglec-5

  Mingui Fu, et al., bioRxiv - Cell Biology 2024

  Quote: ... rabbit anti-VCAM-1 polyclonal antibody (Santa Cruz, 1:1000), rabbit polyclonal anti-β-actin (Santa Cruz ...
• Mapping the endosomal proximity proteome reveals Retromer as a hub for RAB GTPase regulation

  Carlos Antón-Plágaro, et al., bioRxiv - Cell Biology 2024

  Quote: ... VPS29 (Santa Cruz; D-1; sc-398874; 1:500 WB), VPS35 (Abcam ...
• Direct visualization of epithelial microvilli biogenesis

  Isabella M. Gaeta, et al., bioRxiv - Cell Biology 2020

  Quote: ... slides were briefly rinsed with PBS and stained overnight at 4°C with antibodies (mouse anti-EPS8, BD Transduction Laboratories Cat#610144, 1:200; rabbit anti-Villin 1:50, Santa Cruz Cat# SC28283) in 1% NGS in PBS ...
• Aligned and Conductive 3D Collagen Scaffolds for Skeletal Muscle Tissue Engineering

  Ivan M. Basurto, et al., bioRxiv - Bioengineering 2020

  Quote: ... Scaffolds were incubated overnight with antibodies against myosin heavy chain 4 (MF20, mouse monoclonal, eBioscience, 1:200) or MyoD (mouse monoclonal, Santa Cruz, 1:200) in antibody diluent (BD Biosciences) ...
• Ribosomal dysregulation: A conserved pathophysiological mechanism in human depression and mouse chronic stress

  Xiaolu Zhang, et al., bioRxiv - Neuroscience 2023

  Quote: ... Cells were then blocked with 3% BSA and 0.02% Tween 20 for 1 h at room temperature and incubated overnight at 4°C with anti-G3BP1 antibodies (1:250; SC-81940, Santa Cruz Biotechnology, CA), followed by a 1-h incubation with an Alexa488-conjugated anti-immunoglobulin secondary antibody (Molecular Probes ...
• Gene Therapy for Cardiomyopathy associated with Duchenne Muscular Dystrophy in a Pig Model

  Andrea Bähr, et al., bioRxiv - Physiology 2023

  Quote: ... slides were incubated overnight at 4°C with the following antibodies (diluted in blocking buffer): Anti PECAM-1 (sc-376764, Santa Cruz, 1:50), anti NG2 (NG2 antibody ...