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651 - 700 of 8417 citations for 2 Chloro 1 1 trifluoromethyl 1 3 4 9 tetrahydro 2H beta carbolin 2 yl ethan 1 one since 2020

• Synaptotagmins Maintain Diacylglycerol Homeostasis at Endoplasmic Reticulum-Plasma Membrane Contact Sites during Abiotic Stress

  Noemi Ruiz-Lopez, et al., bioRxiv - Molecular Biology 2020

  Quote: ... The following primary antibodies were used for detection of epitope-tagged proteins: mouse monoclonal anti-GFP clone B-2 (1:1000, catalog no. sc-9996, Santa Cruz Bio-technology) and rabbit polyclonal anti-SYT1 antibody (1:5000) ...
• Singlet oxygen-induced signalling depends on the metabolic status of the Chlamydomonas cell

  Waeil Al Youssef, et al., bioRxiv - Cell Biology 2022

  Quote: ... plates were flooded with detection solution containing 0.1 mg mL−1 2-naphthyl sulfate (potassium salt; Santa Cruz Biotechnology, Inc., Dallas, TX, USA) as a chromogenic substrate coupled with 1 mg mL−1 tetrazotized-o-dianisidine chloride (Fast Blue B salt ...
• A plasma membrane-localized polycystin-1/polycystin-2 complex in endothelial cells elicits vasodilation

  Charles E. Mackay, et al., bioRxiv - Physiology 2021

  Quote: ... Membranes were blocked with 5% milk and incubated with one of the following primary antibodies: PC-1 (Santa Cruz), PC-2 (Santa Cruz) ...
• Mouse thy1-positive spermatogonia suppress the proliferation of spermatogonial stem cells by Extracellular vesicles in vitro

  Yu Lin, et al., bioRxiv - Cell Biology 2020

  Quote: ... then incubated overnight at 4°C with rabbit-anti-OCT4 (1:100, Santa Cruz Biotechnology), mouse-anti-PLZF (1:100 ...
• BAP1 and YY1 regulate expression of death receptors in malignant pleural mesothelioma

  Y Ishii, et al., bioRxiv - Cancer Biology 2020

  Quote: ... permiabiliszed and stained with primary antibody to BAP1 (c-4, Santa Cruz-SC28383; 1:50) and then with an AlexaFluor 488-conjugated anti-mouse antibody (Invitrogen A-21202 ...
• Selective localization of Mfn2 near PINK1 enable its preferential ubiquitination by Parkin on mitochondria

  Marta Vranas, et al., bioRxiv - Biochemistry 2021

  Quote: ... Cells were incubated overnight at 4 °C with rabbit anti-Tom20 (1:1000, Santa Cruz) followed by Alexa Fluor® 555 donkey anti-rabbit (Invitrogen) ...
• HD-PTP/PTPN23 hypomorphic mice display lipodystrophy

  Brian A. Davies, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-HD-PTP F-4 mouse monoclonal antibody (1:100, sc-398711, Santa Cruz Biotechnology), anti-actin rabbit polyclonal antibody (1:1000 ...
• Selective Translation Orchestrates Key Signaling Pathways in Primed Pluripotency

  Chikako Okubo, et al., bioRxiv - Cell Biology 2024

  Quote: ... along with the following antibodies: mouse monoclonal anti-OCT3/4 (1:500, Santa Cruz Biotechnology), goat polyclonal anti-SOX2 (1:40 ...
• Tissue-intrinsic Wnt signals antagonize Nodal-driven AVE differentiation

  Sina Schumacher, et al., bioRxiv - Developmental Biology 2023

  Quote: ... Primary antibodies used were anti-Oct3/4 (POU5F1, Santa Cruz Biotechnology sc-5279 1:100), anti-E-Cadherin (CDH1 ...
• NRF2 activators inhibit influenza A virus replication by interfering with nucleo-cytoplasmic export of viral RNPs in an NRF2-independent manner

  Fakhar H. Waqas, et al., bioRxiv - Microbiology 2023

  Quote: ... sulforaphane (SFN; (R)-1-Isothiocyanato-4-(methylsulfinyl)-butane) from (Santa Cruz, Heidelberg, Germany, sc-203099), and selinexor (SEL ...
• Comprehensively characterizing evolutionarily conserved differential dosage compensations of the X chromosome during development and in diseases

  Mengbiao Guo, et al., bioRxiv - Cancer Biology 2022

  Quote: ... then incubated at 4°C overnight with anti-TP53 (1:1000; sc-126,Santa Cruz) and anti-GAPDH (1:5000 ...
• Translation rescue by targeting Ppp1r15a upstream open reading frame in vivo

  Ashley Kidwell, et al., bioRxiv - Physiology 2021

  Quote: ... supernatants were incubated with anti-PP1 antibody conjugated to agarose for 3 hrs at 4 °C (E-9, sc-7482 AC, 25% agarose, Santa Cruz). Samples were washed with washing buffer 5 times (20 mM Tris pH 8 ...
• Proteomic and functional mapping of cardiac Na_V1.5 channel phosphorylation reveals multisite regulation of surface expression and gating

  Maxime Lorenzini, et al., bioRxiv - Physiology 2020

  Quote: ... and the anti-glyceraldehyde 3-phosphate dehydrogenase mouse monoclonal antibody (GAPDH, 1:100000, Santa Cruz Biotechnology). Bound primary antibodies were detected using horseradish peroxidase-conjugated goat anti-mouse secondary antibodies (Cell Signaling Technology ...
• Deletion of Small Ubiquitin-like Modifier-1 Attenuates Behavioral and Anatomical Deficits by Enhancing Functional Autophagic Activities in Huntington Disease

  Uri Nimrod Ramírez-Jarquín, et al., bioRxiv - Neuroscience 2021

  Quote: ... glyceraldehyde-3-phosphate dehydrogenase (Gapdh) (WB-1:1000; no. sc-32233) were obtained from Santa Cruz Biotechnology ...
• Clostridioides difficile spore-entry into intestinal epithelial cells contributes to recurrence of the disease

  Pablo Castro-Córdova, et al., bioRxiv - Microbiology 2020

  Quote: ... in PBS–1% BSA 1 h RT and 1:400 anti-goat conjugated with CFL 488 secondary antibody (green) (SC362255, Santa Cruz Biotechnologies, USA) in PBS–1% BSA for 1 h RT ...
• CRL5-dependent regulation of Arl4c and Arf6 controls hippocampal morphogenesis

  Jisoo S. Han, et al., bioRxiv - Developmental Biology 2020

  Quote: ... washed with TBS-T and incubated overnight with primary antibodies (anti-Actin 1:10000 Santa Cruz Biotechnology #sc1616; anti-Dab1 1:2000 Sigma-Aldrich #HPA052033, anti-Fyn 1:1000 Santa Cruz Biotechnology #sc-16 ...
• Is zebrafish heart regeneration “complete”? Lineage-restricted cardiomyocytes proliferate to pre-injury numbers but some fail to differentiate in fibrotic hearts

  Alberto Bertozzi, et al., bioRxiv - Developmental Biology 2020

  Quote: ... anti-Col1a1a (Developmental Studies Hybridoma Bank #SP1.D8, 1:50), anti-embMHC (Developmental Studies Hybridoma bank, # N2.261, 1:50) and anti-Mef2 (Santa Cruz #SC313, 1:50). Secondary antibodies conjugated to Alexa 488 ...
• Monoallelically-expressed Noncoding RNAs form nucleolar territories on NOR-containing chromosomes and regulate rRNA expression

  Qinyu Hao, et al., bioRxiv - Cell Biology 2022

  Quote: ... Coverslips were then incubated with primary antibodies (anti-FBL, 1:500, Novus Biologicals, NB300-269; anti-RPA194, 1:50, Santa Cruz, sc-48385; anti-UBF, 1:50, Santa Cruz, sc-13125 ...
• Transcriptional networks are dynamically regulated during cell cycle progression in human Pluripotent Stem Cells

  Anna Osnato, Stephanie Brown, Ludovic Vallier, bioRxiv - Cell Biology 2022

  Quote: ... Cells were washed with 1% PBS/BSA and incubated in 1% PBS/BSA with anti-TRA-1-60-antibody mouse monoclonal IgM (1:100, Santa Cruz Biotechnology, Inc.) for 20 min on ice ...
• Distinct TORC1 signalling branches regulate Adc17 proteasome assembly chaperone expression

  Thomas D. Williams, et al., bioRxiv - Cell Biology 2023

  Quote: ... CST, 4370S; αAdc17, Sheep, 1:200, DSTT, DU66321; αP-Rps6, Rabbit, 1:1000, CST, 2211; αHA, Mouse, 1:1000, Santa Cruz Sc-7392) overnight ...
• Anti-cancer potential of cannabis terpenes in a taxol-resistant model of breast cancer

  Andrea M. Tomko, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Primary antibodies (beta-Actin and HRP-conjugated Caspase-3 (Santa Cruz Biotechnology) were added to the milk solution (1:1000 ...
• PAX2 Induces Tubular-Like Structures in Normal and Ovarian Cancer Cells

  Kholoud Alwosaibai, et al., bioRxiv - Cancer Biology 2020

  Quote: ... or 1 hour at room temperature for anti-rabbit PAX2 (1:1000, Santa Cruz). After washing in phosphate-buffered saline (PBS) ...
• Engineered high-density lipoprotein particles that chaperone bioactive lipid mediators to combat endothelial dysfunction and thromboinflammation

  Steven Swendeman, et al., bioRxiv - Biochemistry 2022

  Quote: ... and probed with antibodies to ICAM-1 (1:1000, sc-8439, Santa Cruz Biotech) and Actin (1:5000 ...
• Pathogenic variants of sphingomyelin synthase SMS2 disrupt lipid landscapes in the secretory pathway

  Tolulope Sokoya, et al., bioRxiv - Cell Biology 2022

  Quote: ... goat polyclonal anti-calnexin (Santa Cruz, sc-6495; IF 1:200, IB 1:1,000), rabbit polyclonal anti-β-calnexin (Abcam ...
• Human organoid systems reveal in vitro correlates of fitness for SARS-CoV-2 B.1.1.7

  Mart M. Lamers, et al., bioRxiv - Microbiology 2021

  Quote: ... ciliated cells were stained with anti-AcTub (1:100; Santa Cruz, 6-11B-1), club cells with anti-CC10 (1:200 ...
• Optogenetic control of PRC1 reveals that bridging fibers promote chromosome alignment by overlap length-dependent forces

  Mihaela Jagrić, et al., bioRxiv - Cell Biology 2020

  Quote: ... mouse monoclonal anti-Eg5 antibody (1:100; A-1; sc-365681, Santa Cruz Biotechnology). After washing of primary antibodies with PBS ...
• PU.1 enforces quiescence and limits hematopoietic stem cell expansion during inflammatory stress

  James S. Chavez, et al., bioRxiv - Immunology 2020

  Quote: ... Chromatin was subsequently incubated with 1 μg PU.1 antibody (Santa Cruz; sc-390405) and rotated overnight at 4°C ...
• Sexual dimorphism in a neuronal mechanism of spinal hyperexcitability across rodent and human models of pathological pain

  Annemarie Dedek, et al., bioRxiv - Neuroscience 2021

  Quote: ... anti-Fyn (1:1000) and anti-β-actin (1:10 000) from Santa Cruz; anti-non-phospho-STEP (1:1000 ...
• Suppression of aminoglycoside-induced premature termination codon readthrough by the TRP channel inhibitor AC1903

  Alireza Baradaran-Heravi, et al., bioRxiv - Pharmacology and Toxicology 2021

  Quote: ... DO-1 mouse anti-p53 antibody (1:400, Santa Cruz sc-126, TX, USA) and mouse anti-vinculin antibody (1:600 ...
• Myoglobin promotes cardiomyocyte differentiation through oxidatively modulating the Hippo Kinase Pathway

  Krithika Rao, et al., bioRxiv - Cell Biology 2022

  Quote: ... Mb (1:1000, LS-C144978 LS Bio or 1:1000, sc-393020 Santa Cruz), Tubulin (1:1000 ...
• A genetic and physiological model of renal dysfunction in Lowe syndrome

  Navyashree A Ramesh, et al., bioRxiv - Cell Biology 2024

  Quote: ... 1:1000 anti-mcherry (Thermo, PA5-34974) 1:2000 anti-GFP (Santa cruz, sc9996). Following this ...
• PGM3 inhibition Shows cooperative Effects With Erastin inducing Pancreatic cancer cell death via activation of the Unfolded Protein Response

  Barbara Zerbato, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Keap1 (sc-365626, 1:1000) and Vinculin (#sc-5573, 1:10000) from Santa Cruz Biotechnology Inc ...
• The large GTPase Guanylate-Binding Protein-1 (GBP-1) promotes mitochondrial fission in glioblastoma

  Ryan C. Kalb, et al., bioRxiv - Cancer Biology 2024

  Quote: ... The primary antibodies were rat anti-hGBP-1 (1b1) (Santa Cruz Biotechnology 1:10,000); mouse anti-MMP1 Mab 901 (R&D Systems 1:750) ...
• Human ADA2 deficiency is characterized by the absence of an intracellular hypoglycosylated form of adenosine deaminase 2

  Lisa Ehlers, et al., bioRxiv - Immunology 2024

  Quote: ... anti-LAMP-1 (clone H4A3, #sc-20011; 1:500; Santa Cruz Biotechnology; RRID: AB_626853), anti-CD98 (clone E-5 ...
• CryoET shows cofilactin filaments inside the microtubule lumen

  Camilla Ventura Santos, et al., bioRxiv - Cell Biology 2023

  Quote: ... Membranes were incubated with primary antibodies at 4°C over-night or for 1 h at room temperature at the following dilutions: α-tubulin (sc-32293, Santa Cruz, 1:5000 in 5% milk, mouse), anti-cofilin (gift from Anna Marie Sokac ...
• Autophagy maintains the homeostatic environment in the male reproductive accessory organs playing a key role in fertility

  Adil Jaulim, et al., bioRxiv - Cell Biology 2023

  Quote: ... or Tris-EDTA buffer (10mM Tris Base, 1mM EDTA Solution, 0.05% Tween 20, pH 9) for AR (Santa Cruz, sc-816, 1:500) and tGFP (Thermo Fisher ...
• TGF-β inhibitor accelerates BMP4-induced cochlear gap junction formation during in vitro differentiation of embryonic stem cells

  Ichiro Fukunaga, et al., bioRxiv - Cell Biology 2020

  Quote: ... 1 μM PD0325901 (Santa Cruz), and 1,000 U ml−1 of leukemia inhibitory factor (Millipore).
• Endoplasmic Reticulum Associated Degradation (ERAD) Deficiency Promotes Mitochondrial Dysfunction and Transcriptional Rewiring in Human Hepatic Cells

  Xiaoqing Yang, et al., bioRxiv - Cell Biology 2020

  Quote: ... JNK1 (Santa Cruz, 1:800), RIPK1 (Affinity ...
• Assessment of ethanol-induced toxicity on iPSC-derived human dopaminergic neurons using a novel high-throughput mitochondrial neuronal health (MNH) assay

  Annika Zink, et al., bioRxiv - Cell Biology 2020

  Quote: ... SOX2 (Santa Cruz, 1:100), TUJ1 (Sigma-Aldrich ...
• Assessment of ethanol-induced toxicity on iPSC-derived human dopaminergic neurons using a novel high-throughput mitochondrial neuronal health (MNH) assay

  Annika Zink, et al., bioRxiv - Cell Biology 2020

  Quote: ... OCT4 (Santa Cruz, 1:300), TRA-1-60 (Millipore ...
• Human spinal cord differentiation proceeds rapidly in vitro and only initially maintains differentiation pace in a heterologous environment

  Alwyn Dady, et al., bioRxiv - Developmental Biology 2021

  Quote: ... TFAPα (1/10, Santa Cruz), HNK1 (1/10 ...
• Cytoplasmic Switch of ARS2 Isoforms Promotes Nonsense-Mediated mRNA Decay and Arsenic Sensitivity

  Monica Mesa-Perez, et al., bioRxiv - Molecular Biology 2021

  Quote: ... UPF1 (1:500, Santa Cruz), UPF1 (1:1000 ...
• Cytoplasmic Switch of ARS2 Isoforms Promotes Nonsense-Mediated mRNA Decay and Arsenic Sensitivity

  Monica Mesa-Perez, et al., bioRxiv - Molecular Biology 2021

  Quote: ... SMG1 (1:500, Santa Cruz), DHX34 (1:1000 ...
• A versatile system to introduce clusters of genomic double-strand breaks in large cell populations

  Thorsten Kolb, et al., bioRxiv - Genomics 2020

  Quote: ... 53BP1 1:750 (Santa Cruz), Ki67 1:100 (Abcam) ...
• A CTGF-YAP regulatory pathway is essential for angiogenesis and barriergenesis in the retina

  Sohyun Moon, et al., bioRxiv - Developmental Biology 2020

  Quote: ... GAPDH (1:1,000; Santa Cruz). CTGF antibodies (1:500 ...
• A CTGF-YAP regulatory pathway is essential for angiogenesis and barriergenesis in the retina

  Sohyun Moon, et al., bioRxiv - Developmental Biology 2020

  Quote: ... YAP (1:500; Santa Cruz), GAPDH (1:1,000 ...
• A conserved expression signature predicts growth rate and reveals cell & lineage-specific differences

  Zhisheng Jiang, et al., bioRxiv - Systems Biology 2021

  Quote: ... GAPDH (Santa Cruz, 1:5000), at 4 °C for 16 h ...
• Partial inhibition of mitochondrial complex I attenuates neurodegeneration and restores energy homeostasis and synaptic function in a symptomatic Alzheimer’s mouse model

  Andrea Stojakovic, et al., bioRxiv - Neuroscience 2020

  Quote: ... Synaptophysin (1:200, Santa Cruz Biotechnology ...
• Partial inhibition of mitochondrial complex I attenuates neurodegeneration and restores energy homeostasis and synaptic function in a symptomatic Alzheimer’s mouse model

  Andrea Stojakovic, et al., bioRxiv - Neuroscience 2020

  Quote: ... BDNF (1:200, Santa Cruz Biotechnology ...
• Intranasal Administration of Functionalized Soot Particles Disrupts Olfactory Sensory Neuron Progenitor Cells in the Neuroepithelium

  Jordan N. Norwood, et al., bioRxiv - Neuroscience 2020

  Quote: ... Pax6 (Santa Cruz, 1:250), and p63 (Abcam ...