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601 - 650 of 8417 citations for 2 Chloro 1 1 trifluoromethyl 1 3 4 9 tetrahydro 2H beta carbolin 2 yl ethan 1 one since 2020

• Structural basis for mTORC1-dependent regulation of the lysosomal and autophagic transcription factor TFEB

  Zhicheng Cui, et al., bioRxiv - Cell Biology 2022

  Quote: ... antibodies to GAPDH (6C5) (Cat# sc-32233 - 1:15000 WB) and LAMP-1 (H4A3) (Cat# sc-20011 - 1:500 IF) were from Santa Cruz; antibody to HA.11 Epitope Tag (Cat# 901513 ...
• α-syn overexpression, NRF2 suppression, and enhanced ferroptosis create a vicious cycle of neuronal loss in Parkinson’s disease

  A Anandhan, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-GPx4 (1:1000, sc-166570), anti-AKR1C1 (1:1000, sc-398596), and anti-GCLM (1:1000, sc-166603) were from Santa Cruz Biotechnology (Dallas ...
• Site-Specific Knockdown of Microglia in the Locus Coeruleus Regulates Hypervigilant Responses to Social Stress in Female Rats

  Brittany S. Pate, et al., bioRxiv - Neuroscience 2022

  Quote: ... PVDF membranes incubated overnight at 4°C with the following primary antibodies diluted in 1:1 Blok/0.1M PBS + 0.2% Tween-20 : mouse anti-GAPDH (1:1000, Santa Cruz, Santa Cruz, CA), rabbit anti-CX3CL1 (1:1000 ...
• Haloperidol-induced immediate early genes in striatopallidal neurons requires the converging action of cAMP/PKA/DARPP-32 and mTOR pathways

  Oriane Onimus, et al., bioRxiv - Neuroscience 2022

  Quote: ... Antibodies for cFos (1:400, #sc-52), Arc (1:400, #sc-17839), and Zif268 (1:400, #sc-189) were purchased from Santa Cruz Biotechnology [29] ...
• The Kv2.2 channel mediates the inhibition of Prostaglandin E2 on glucose-stimulated insulin secretion in pancreatic β-cells

  Chengfang Pan, et al., bioRxiv - Physiology 2024

  Quote: ... Cells were then incubated in primary antibody solution (primary antibody (anti-EP1: 1:200, Ab217925, Abcam, UK; anti-EP2: 1:200, Ab167171, Abcam; anti-EP3: 1:200, Sc-57105, Santa Cruz Biotechnology ...
• Ex vivo tissue perturbations coupled to single cell RNA-seq reveal multi-lineage cell circuit dynamics in human lung fibrogenesis

  Niklas J. Lang, et al., bioRxiv - Cell Biology 2023

  Quote: ... 10% normal donkey serum or 1% BSA were used for blocking nonspecific binding and primary antibodies were incubated (VWA1 1:100, Proteintech, 14322-1-AP; CLDN5 1:100, Santa Cruz, sc-374221 ...
• A potent agonist-based PROTAC targeting Pregnane X Receptor that delays colon cancer relapse

  Lucile Bansard, et al., bioRxiv - Cancer Biology 2024

  Quote: ... final dilution: 1/500), Ubiquitin (sc-166553, final dilution: 1/500) and PXR (sc-48340, final dilution: 1/500) from Santa Cruz, GSPT1 (ab126090 ...
• Epigenetic delineation of the earliest cardiac lineage segregation by single-cell multi-omics

  Peng Xie, et al., bioRxiv - Molecular Biology 2024

  Quote: Antibody against HAND1 (sc-390376) (WB: 1:1000, IF for embryos: 1:100, IF for cells: 1:200) was purchased from Santa Cruz. Antibody against FOXF1 (Abclonal ...
• Annexin A2 and lamin B join membrane recycling compartments for the assembly of biomolecular condensates operating in mitotic partitioning

  Ann Kari Grindheim, et al., bioRxiv - Cell Biology 2024

  Quote: ... while the mouse monoclonal antibody against LAMP-1 (H5G11; 1:200 dilution) and rabbit polyclonal antibody against Rab7 (R4779; 1:50 dilution) were purchased from Santa Cruz Biotechnology and Sigma ...
• G protein subunit Gγ13-mediated signaling pathway is critical to the inflammation resolution and functional recovery of severely injured lungs

  Yi-Hong Li, et al., bioRxiv - Immunology 2024

  Quote: ... followed by incubation at 4◦C overnight with primary antibodies diluted in the blocking buffer (rabbit anti-Dclk1 1:1000, Abcam, ab31704; rabbit anti-Dclk1-488 1:1000, Abcam, ab202754; rabbit anti-Gnat3 1:500, Santa Cruz Biotechnology ...
• Parvalbumin interneuron ErbB4 controls ongoing network oscillations and olfactory behaviors in mice

  Bin Hu, et al., bioRxiv - Neuroscience 2024

  Quote: Rabbit polyclonal anti-ErbB4 antibody (sc-283, 1:2000, or 1:1000 for blotting, 1:100 for staining) was purchased from Santa Cruz, mouse monoclonal anti-PV antibody (P3088 ...
• Binding of CEP152 to PLK4 stimulates kinase activity to promote centriole assembly

  Hazal Kübra Gürkaşlar, Ingrid Hoffmann, bioRxiv - Cell Biology 2024

  Quote: ... mouse anti-ninein (1:1000 IF; F5), mouse anti-SAS-6 (1:500 IF, 1:100 U-ExM) from Santa Cruz Biotechnology ...
• Hydroxylation of Actin Impairs Cell Motility Through Blocking its’ Histidine Methylation

  Zhenzhen Zi, et al., bioRxiv - Biochemistry 2021

  Quote: ... Anti-CUL-2 Antibody (C-4) (Santa Cruz, sc-166506), Anti-Flag (Sigma ...
• Intrinsic BMP inhibitor Gremlin regulates lung alveolar progenitor cell proliferation and differentiation

  Toyoshi Yanagihara, et al., bioRxiv - Molecular Biology 2022

  Quote: ... BMP-2/4 (sc-137087, Santa Cruz for western blot), BMP2 (PA578874 ...
• Syndecan-4^-/- mice have smaller muscle fibers, increased Akt/mTOR/S6K1 and Notch/HES-1 pathways, and alterations in extracellular matrix components

  Sissel Beate Rønning, et al., bioRxiv - Cell Biology 2020

  Quote: ... anti-Pax-7 (1:500, sc-81648, 1:500, 1x casein, Santa Cruz) anti-decorin (1:500 ...
• Inhibitors of the Bub1 spindle assembly checkpoint kinase: Synthesis of BAY-320 and comparison with 2OH-BNPP1

  Ilma Amalina, et al., bioRxiv - Cell Biology 2020

  Quote: ... mouse anti-p53 (DO-1) (Santa Cruz Biotechnology cat#sc-126, 1:1000). Membranes were then washed three times in TBST and incubated for at least 1 hr with appropriate horseradish-peroxidase-conjugated secondary antibodies (1:2000) ...
• Acquisition of cellular properties during alveolar formation requires differential activity and distribution of mitochondria

  Kuan Zhang, et al., bioRxiv - Developmental Biology 2021

  Quote: ... rat anti-PECAM-1 (CD31) (1:150, Santa Cruz Biotechnology, Cat# sc-18916), rabbit anti-PDGFRA (1:150 ...
• The Alzheimer’s gene SORL1 is a regulator of endosomal traffic and recycling in human neurons

  Swati Mishra, et al., bioRxiv - Cell Biology 2022

  Quote: ... Lysosome associated membrane protein-1 (LAMP1) at 1:250 (#sc 2011; Santa Cruz); Tropomyosin receptor kinase B (TRKB ...
• Extracellular Vesicles Analysis in the COVID-19 Era: Insights on Serum Inactivation Protocols Towards Downstream Isolation and Analysis

  Roberto Frigerio, et al., bioRxiv - Biochemistry 2020

  Quote: ... anti-TSG101 (1:1000, Novus Bio) and anti-Apo1 (1:1000, Santa Cruz). After washing with T-TBS ...
• IPSC-derived midbrain astrocytes from Parkinson’s disease patients carrying pathogenic SNCA mutations exhibit alpha-synuclein aggregation, mitochondrial fragmentation and excess calcium release

  Peter A. Barbuti, et al., bioRxiv - Neuroscience 2020

  Quote: ... –TUBB3 (1:300; Covance, MRB-435P) -Vimentin (1:100; Santa Cruz, sc-373717). Secondary antibodies used were ...
• Translational profiling of mouse dopaminoceptive neurons reveals a role of PGE2 in dorsal striatum

  Enrica Montalban, et al., bioRxiv - Neuroscience 2020

  Quote: ... Vehicle (DMSO in PBS, 1/1) or misoprostol (Santa Cruz Biotechnology, #SC-201264), were infused at a dose of 50 μg.kg−1.day−1 ...
• A kinase-independent function of cyclin-dependent kinase 6 promotes outer radial glia expansion and neocortical folding

  Lei Wang, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-SATB2 (Millipore, ABE600, 1:2,000; Santa Cruz Biotechnology, sc-81376, 1:50), anti-TBR1 (Millipore ...
• Inhibition of histone acetyltranserase function radiosensitizes CREBBP/EP300 mutants via repression of homologous recombination, potentially targeting a novel gain of function

  Manish Kumar, et al., bioRxiv - Cancer Biology 2020

  Quote: ... 53BP1 (1:200, CST) or anti-BRCA1 primary antibody (1:500, Santa Cruz) overnight at 4°C ...
• Specificity of Gβ and γ subunits to the SNARE complex both at rest and after α_2a adrenergic receptor stimulation

  Yun Young Yim, et al., bioRxiv - Biochemistry 2021

  Quote: ... and rabbit anti-Gβ (Santa Cruz, sc-378, 1:10,000 and 1:5000) were used ...
• Inhibitory effect of the TSG-6 on the BMP-4/Smad signaling pathway and odonto/osteogenic differentiation of dental pulp stem cells

  Ying Wang, et al., bioRxiv - Cell Biology 2020

  Quote: The antibodies used for immunohistochemistry included DMP-1 (1:100 dilution, Santa Cruz), DSPP (1:100 dilution ...
• Inhibitory effect of the TSG-6 on the BMP-4/Smad signaling pathway and odonto/osteogenic differentiation of dental pulp stem cells

  Ying Wang, et al., bioRxiv - Cell Biology 2020

  Quote: ... the primary antibodies were as follows: DMP-1 (1:200 dilution, Santa Cruz) and DSPP (1:200 dilution ...
• Retinoic acid treatment recruits macrophages and increases axonal regeneration after optic nerve injury in the frog Rana pipiens

  Valeria De La Rosa-Reyes, et al., bioRxiv - Neuroscience 2021

  Quote: ... which were anti-Arginase 1 (1:50; catalog # sc-271430; Santa Cruz Biotechnology), anti-CD68 (ED1 ...
• PSGL-1 inhibits HIV-1 infection by restricting actin dynamics and sequestering HIV envelope proteins

  Ying Liu, et al., bioRxiv - Microbiology 2020

  Quote: ... or Western blotting: anti-PSGL-1 (Santa Cruz Biotech, sc-13535, 1:200), anti-cofilin (Cell Signaling ...
• NCLX controls hepatic mitochondrial Ca²⁺ extrusion and couples hormone-mediated mitochondrial Ca²⁺ oscillations with gluconeogenesis

  Mahmoud Taha, et al., bioRxiv - Physiology 2024

  Quote: ... for 1 h or an anti-mouse (1:5000, sc-2005, Santa Cruz) solution for 1 h ...
• PDGFRα/β heterodimer activation negatively affects downstream ERK1/2 signaling and cellular proliferation

  Maria B. Campaña, et al., bioRxiv - Cell Biology 2023

  Quote: ... and Myosin ID (1:500; H-1; sc-515292; Santa Cruz Biotechnology, Inc). For fluorescence intensity measurements ...
• Loss of CLN3 in microglia leads to impaired lipid metabolism and myelin turnover

  Seda Yasa, et al., bioRxiv - Neuroscience 2024

  Quote: ... anti-Lamp1 (WB: 1:1000, IF: 1:100, Santa Cruz Biotech sc-19992), anti-Lamp2a (WB ...
• Synergistic induction of blood-brain barrier properties

  Gergő Porkoláb, et al., bioRxiv - Bioengineering 2023

  Quote: ... rabbit anti-PECAM-1 (Santa Cruz, cat# sc-1506-R, AB_831096, 1:200), rabbit anti-β-catenin (Sigma-Aldrich ...
• Neuroblastoma-associated chromosomal aberrations drive cell identity loss in human neural crest via disruption of developmental regulators

  Ingrid M. Saldana-Guerrero, et al., bioRxiv - Cancer Biology 2022

  Quote: ... MASH1 (ASCL1) (Abcam, Ab211327, 1:100 or Santa Cruz, SC-374104, 1:500); Ki67 (Abcam ...
• Actin nucleators safeguard replication forks by limiting nascent strand degradation

  Jadwiga Nieminuszczy, et al., bioRxiv - Molecular Biology 2023

  Quote: ... DIAPH1 (Bethyl, A300-077A-T, 1:1000; Santa Cruz, sc-373807, 1:500), CHK1 – phospho S345 (Cell Signalling ...
• Chlamydial protease-like activating factor targets SLC7A11 for degradation to induce ferroptosis and facilitate dissemination

  Wentao Chen, et al., bioRxiv - Microbiology 2023

  Quote: ... fibroblast-specific protein 1 (FSP1; 1:500, Santa Cruz Biotechnology Cat# sc-377120), TfR1(1:500 ...
• The Parkinson’s Disease related mutant VPS35 (D620N) amplifies the LRRK2 response to endolysosomal stress

  Katy R. McCarron, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-ALIX (1:1,000 WB, 1:500 IF, Santa Cruz Biotechnology; sc-53540), anti-Cathepsin D (1:2,000 WB ...
• Muti-omics characterization reveals brain-wide disruption of synapses and region- and age-specific changes in neurons and glia in Sp4 mutant mice, a genetic model of schizophrenia and bipolar disorder

  Min Jee Kwon, et al., bioRxiv - Neuroscience 2024

  Quote: ... 1:250 Mouse anti-Sp4 antibody (B-1, Santa Cruz Biotechnology, sc-390124) followed by 1:25,000 anti-mouse antibody (Thermo Fisher Scientific ...
• A survey of hypothalamic phenotypes identifies molecular and behavioral consequences of MYT1L haploinsufficiency in male and female mice

  Susan E. Maloney, et al., bioRxiv - Animal Behavior and Cognition 2024

  Quote: ... and 1:500 mouse anti-AVP (1:500, Santa Cruz Biotech, sc-9888). Slices incubated in primary antibodies overnight at 4C on a horizontal mixer ...
• Dietary Monoterpenoids As a New Class of Allosteric Human Aryl Hydrocarbon Receptor Antagonists

  Karolína Poulíková, et al., bioRxiv - Pharmacology and Toxicology 2020

  Quote: ... Immuno-detection was performed using a primary antibody against CYP1A1 (mouse monoclonal, sc-393979, A-9, dilution 1:100, Santa Cruz Biotechnology) and β-actin (mouse monoclonal ...
• Native size exclusion chromatography-based mass spectrometry (SEC-MS) identifies novel components of the Heat Shock Protein 90-dependent proteome

  Rahul S. Samant, et al., bioRxiv - Biochemistry 2022

  Quote: ... Antibodies for HSP90α/β (sc-7947, 1:500), CDC37 (sc-5617, 1:500), and AHA1 (sc-50527, 1:500) were from Santa Cruz Biotechnology ...
• Long-term dynamic changes of NMDA receptors following an excitotoxic challenge

  Alberto Granzotto, et al., bioRxiv - Neuroscience 2022

  Quote: ... Cells were incubated for 1 h at RT with anti-GluN1 antibody (1:200, Alomone) and anti-NOS1 antibody (1:50, Santa Cruz Biotechnology) in the blocking solution ...
• Peripheral neuropathy linked mRNA export factor GANP reshapes gene regulation in human motor neurons

  Rosa Woldegebriel, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit α-GAPDH 1:1000 (#14C10, Cell Signalling) with secondary 1:5000 (#111-035-144, Jackson) and mouse α-NEFL 1:1000 (#sc39073, Santa Cruz) with secondary 1:5000 (#115-035-146 ...
• High Cysteinyl Leukotriene Receptor 1 Expression Correlates with Poor Survival of Uveal Melanoma Patients and Cognate Antagonist Drugs Modulate the Growth, Cancer Secretome, and Metabolism of Uveal Melanoma Cells

  Kayleigh Slater, et al., bioRxiv - Cancer Biology 2020

  Quote: ... and probed with primary antibodies (CysLT1 : Abcam [ab151484], 1:1000, CysLT2 : Cayman Chemical [CAY120560] 1:1000, Alpha-Tubulin : Santa Cruz, 1:200). Secondary antibodies were anti-mouse IgG HRP-linked (Cell Signalling [7076S] 1:1000) ...
• Phospho-β-catenin expression in primary and metastatic melanomas and in tumor-free visceral tissues

  Joel Pinczewski, et al., bioRxiv - Pathology 2020

  Quote: Working concentrations of antibodies to βcat (1:500, Epitomics, Burlingame, CA # 1247-1) and phospho-βcat (pS33-βcat 1:200, Santa Cruz, Santa Cruz, CA # SC-16743-R ...
• Site-Specific Knockdown of Microglia in the Locus Coeruleus Regulates Hypervigilant Responses to Social Stress in Female Rats

  Brittany S. Pate, et al., bioRxiv - Neuroscience 2022

  Quote: ... PVDF membranes incubated overnight at 4°C with the following primary antibodies diluted in 1:1 Blok/0.1M PBS + 0.2% Tween-20 : mouse anti-GAPDH (1:1000, Santa Cruz, Santa Cruz, CA), rabbit anti-CX3CL1 (1:1000 ...
• IMPDH2 filaments protect from neurodegeneration in AMPD2 deficiency

  Marco Flores-Mendez, et al., bioRxiv - Neuroscience 2024

  Quote: ... 1:1000; CD68, Bio Rad MCA1957, 1:250; NEUN, Millipore MAB377, 1:2000; GFAP, Aves Lab 75-240, 1:1000, S6, Santa Cruz sc74459 ...
• Stimulation of VTA dopamine inputs to LH upregulates orexin neuronal activity in a DRD2-dependent manner

  Masaya Harada, et al., bioRxiv - Neuroscience 2024

  Quote: ... before staining with the respective primary antibodies (NAc and LH with αGFP chicken 1:1000, Aves Labs ref GFP-1010; αmCherry rabbit, 1:1000, abcam ab167453; and αOrexin goat, 1:500, Santa Cruz Biotech ...
• Analysis of the Distal Urinary Tract in Larval and Adult Zebrafish Reveals Unrecognized Homology to the Human System

  Ibrahim Jubber, et al., bioRxiv - Evolutionary Biology 2023

  Quote: ... sc-15179 (Goat polyclonal) at 1:400 dilution for zebrafish tissue and 1:100-1:400 dilution for human tissue (Santa Cruz Biotechnology), Cytokeratin 5/6 (mouse monoclonal ...
• Nuclear receptor E75/NR1D2 drives tumor malignant transformation by integrating Hippo and Notch pathways

  Xianping Wang, et al., bioRxiv - Cancer Biology 2024

  Quote: ... and rabbit anti-HA (CST, 1:200), rabbit anti-Flag (CST, 1:200) and mouse anti- Su(H) (Santa Cruz, 1:100), mouse anti-NICD (DSHB ...
• Imbalance of Neuregulin1-ErbB2/3 signaling underlies altered myelin homeostasis in models of Charcot-Marie-Tooth disease type 4H

  Lara El-Bazzal, et al., bioRxiv - Neuroscience 2022

  Quote: ... The membrane was then incubated overnight with the following primary antibodies: mouse anti-Neuregulin1α/β1/2 (D10) (1:500) (#sc-393009; Santa Cruz Biotechnology, USA), rabbit anti-phospho-Akt (Ser473 ...