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301 - 350 of 7988 citations for 3 Methyl 1 6 naphthyridine 2 carboximidamide hydrochloride since 2020

• The V-ATPase/ATG16L1 axis is controlled by the V₁H subunit

  Lewis Timimi, et al., bioRxiv - Molecular Biology 2023

  Quote: ... mouse monoclonal anti-ATP6V1B1/2 (Santa Cruz Biotechnology, sc-55544, WB 1:1000), rabbit monoclonal anti-ATP6V1D (Abcam ...
• Caffeine stabilises fission yeast Wee1 in a Rad24-dependent manner but attenuates its expression in response to DNA damage identifying a putative role for TORC1 in mediating its effects on cell cycle progression

  John P. Alao, et al., bioRxiv - Cell Biology 2020

  Quote: ... Myc (9E10) and pan 14-3-3 (K-19) proteins were from Santa Cruz Biotechnology (Heidelberg ...
• Pressure drives rapid burst-like collective migration from 3D cancer aggregates

  Swetha Raghuraman, et al., bioRxiv - Biophysics 2021

  Quote: ... the samples were incubated with the primary antibody (monoclonal mouse anti-Caspase-3, 1:100, Santa Cruz, sc-56053 ...
• DBF4, not DRF1, is the crucial regulator of CDC7 kinase at replication forks

  Anja Göder, et al., bioRxiv - Biochemistry 2023

  Quote: Primary antibodies were diluted in 3% skim milk/TBS-T: CHK1 (sc8408; Santa Cruz Biotech; 1:1000), CDC7 (DCS-342 ...
• Novel high throughput 3D ECM remodeling assay identifies MEK as key driver of fibrotic fibroblast activity

  Chen-Yi Liao, et al., bioRxiv - Cell Biology 2024

  Quote: ... mouse anti-human glyceraldehyde 3-phosphate dehydrogenase (GAPDH) (1:1000; sc-32233; Santa Cruz, Dallas, TX, USA), Horseradish peroxidase (HRP)-conjugated goat anti-rabbit IgG (1:10,000 ...
• Gravin-associated kinase signaling networks coordinate γ-tubulin organization at mitotic spindle poles

  Paula J. Bucko, et al., bioRxiv - Cell Biology 2020

  Quote: ... clone H-3 (Santa Cruz Biotechnology ...
• Neural-specific alterations in glycosphingolipid biosynthesis and cell signaling associated with two human ganglioside GM3 Synthase Deficiency variants

  Michelle Dookwah, et al., bioRxiv - Neuroscience 2021

  Quote: ... anti-caspase 3 (Santa Cruz, caspase-3 Antibody 31A1067 ...
• Immune-evasion of KRAS-mutant lung adenocarcinoma mediated by cAMP response element-binding protein

  Georgia A. Giotopoulou, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-histone 3 (Santa Cruz, Sta ...
• HSP90 facilitates oncogenic alterations of metabolism in B-cell lymphomas

  M. Nieves Calvo-Vidal, et al., bioRxiv - Cancer Biology 2020

  Quote: ... cells were blocked with Duolink blocking buffer for 30 m and incubated for 1 h at 37 °C in the presence of primary antibodies for IMPDH (F-6, sc-166551, Santa Cruz) and CTPS1 (sc-131474 ...
• Cell cycle checkpoints cooperate to suppress DNA and RNA associated molecular pattern recognition and anti-tumor immune responses

  Jie Chen, et al., bioRxiv - Cell Biology 2020

  Quote: ... cells were washed once with 6 ml 1% BSA/PBS and resuspended in PBS containing 10 μg/ml propidium iodide (Santa Cruz) and 100 μg/ml RNase A (Qiagen) ...
• Crucial role for Sodium Hydrogen Exchangers in SGLT2 inhibitor-induced arterial relaxations

  Elizabeth A Forrester, et al., bioRxiv - Physiology 2023

  Quote: ... Membranes were blocked for at least 0.5 hour in 3% BSA-PBS and incubated overnight at 4°C with the primary SGLT2 mouse monoclonal antibody (D-6, sc-393350, 1/200 dilution, Santa Cruz). The membranes were incubated with highly adsorbed horseradish peroxidase-conjugated goat anti-mouse IgG (A16078 ...
• Defective interferon signaling in the circulating monocytes of type 2 diabetic mice

  Shunsuke Omodaka, et al., bioRxiv - Neuroscience 2024

  Quote: ... Peripheral blood was taken by heart puncture and mixed with acid-citrate dextrose solution (6:1, V: V, Santa Cruz Biotechnology) as previously described 28 ...
• The adenoviral E1B-55k protein present in HEK293 cells mediates abnormal accumulation of key WNT signaling proteins in large cytoplasmic aggregates

  Petter Angell Olsen, Stefan Krauss, bioRxiv - Cell Biology 2021

  Quote: ... The following primary antibodies and dilutions were used: Tankyrase-1/2 (E10) (Santa Cruz Biotechnology; sc-365897; 1:200), AXIN1 (C76H11 ...
• The X-linked intellectual disability gene product and E3 ubiquitin ligase KLHL15 degrades doublecortin proteins to constrain neuronal dendritogenesis

  Jianing Song, et al., bioRxiv - Biochemistry 2020

  Quote: ... mouse anti-Doublecortin (E-6) (sc-271390, Santa Cruz), rabbit anti-Doublecortin (4604 ...
• Nardilysin-Regulated Scission Mechanism Activates Polo-like Kinase 3 to Suppress the Development of Pancreatic Cancer

  Jie Fu, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-NRDC (A-6) (sc-137199; Santa Cruz Biotechnology), or anti-c-Fos antibody (2250 ...
• NS5A domain I antagonises PKR to facilitate the assembly of infectious hepatitis C virus particles

  Shucheng Chen, Mark Harris, bioRxiv - Microbiology 2022

  Quote: ... mouse-anti p65 (F-6) (Santa Cruz; sc-8008), rabbit anti-eIF2α (Cell Signaling ...
• Interplay between ß-propeller subunits WDR26 and muskelin regulates the CTLH E3 ligase supramolecular complex

  Matthew E.R. Maitland, et al., bioRxiv - Molecular Biology 2024

  Quote: ... and HMGCS1 (A-6, sc-166763, Santa Cruz Biotechnology).
• Low concentrations of ethylene bisdithiocarbamate pesticides maneb and mancozeb impair manganese and zinc homeostasis to induce oxidative stress and caspase-dependent apoptosis in human hepatocytes

  Kilian Petitjean, et al., bioRxiv - Pharmacology and Toxicology 2023

  Quote: ... and HSC70 (B-6, sc-526-G Santa Cruz). Primary antibodies were detected using secondary antibodies coupled to horseradish peroxidase (Dako ...
• In vivo imaging in transgenic songbirds reveals superdiffusive neuron migration in the adult brain

  Naomi R. Shvedov, et al., bioRxiv - Neuroscience 2023

  Quote: ... migratory neurons (Santa Cruz Biotechnology, sc-271390 (E-6), lot ...
• FICD deficiency protects mice from hypertrophy-induced heart failure via BiP-mediated activation of the UPR^ER and ER-phagy

  Shannon M. Lacy, et al., bioRxiv - Cell Biology 2024

  Quote: ... HSC70 (B-6)(Santa Cruz Biotechnology, sc-7298, mAb), LAMP1 (E6N3R)(Cell Signaling ...
• A functional network signature in the developing cerebellum: evidence from a preclinical model of autism

  María Berenice Soria-Ortiz, et al., bioRxiv - Neuroscience 2021

  Quote: ... with TBS-T and primary antibodies were detected after incubation (3 h) with either rabbit anti-goat IgG-AP (1:2000) or goat anti-rabbit IgG-AP (1:2000) (Santa Cruz, Dallas, TX, USA). Alkaline phosphatase activity was detected with BCIP/NBT AP-conjugate substrate reaction kit (Bio-Rad ...
• Human papillomavirus 16 E2 repression of TWIST1 transcription is a potential mediator of HPV16 cancer outcomes

  Christian T Fontan, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (sc-47724) and p53 (sc-47698) at 1:1000 dilution from Santa Cruz Biotechnology and Twist1 (25465-1-AP ...
• Molecular programs of fibrotic change in aging human lung

  Jasmine Lee, et al., bioRxiv - Genomics 2021

  Quote: ... then at room temperature for 3 hours with secondary antibody (Santa Cruz Biotechnology, cat. sc-2005, 1:1000). Sections were developed in DAB working solution (Vector Laboratories ...
• Important anatomical, age-related, and species considerations regarding ocular fibulin-3 (EFEMP1) analysis

  Steffi Daniel, John D. Hulleman, bioRxiv - Neuroscience 2022

  Quote: ... The antibodies used were as follows: anti-fibulin-3 antibody (1:200, Santa Cruz, #sc-365224, Dallas, TX), anti-fibulin-3 antibody (1:100 ...
• Enhancement of response learning in male rats with intrastriatal infusions of a BDNF - TrkB agonist, 7,8-dihydroxyflavone

  Robert S. Gardner, et al., bioRxiv - Neuroscience 2024

  Quote: Aliquots of striata were suspended in homogenization buffer (1 mg tissue: 3 µl RIPA buffer; Santa Cruz: 24948) and homogenized (Polytron PT 1600 E ...
• Stimulus-specific processing of the plasma membrane receptor-like kinase FERONIA in Arabidopsis thaliana

  Cassidy S. Cornblatt, et al., bioRxiv - Plant Biology 2021

  Quote: ... Antibody dilutions used were 1:500 for α-GFP (B-2, Santa Cruz Biotechnology), 1:2500 for α-calnexin (CNX1/2 ...
• Reactive oxygen species prevent lysosome coalescence during PIKfyve inhibition

  Golam T. Saffi, et al., bioRxiv - Cell Biology 2021

  Quote: ... and goat polyclonal antibody against dynamin 2 (1:1000, sc-6400, Santa Cruz Biotechnology). Secondary antibodies were raised in donkey (Bethyl ...
• Novel regulation of the transcription factor ZHX2 by N-terminal methylation

  Meghan M. Conner, et al., bioRxiv - Biochemistry 2021

  Quote: ... mouse anti-ZHX2 (D-2) (1:1000; sc-393399, Santa Cruz Antibodies, Dallas, TX), rabbit anti-CYP26A1 (1:1000 ...
• H₂S Prodrug, SG-1002, Protects Against Myocardial Oxidative Damage and Hypertrophy via Induction of Cystathionine β-Synthase and Antioxidant Proteins

  Rahib K. Islam, et al., bioRxiv - Cell Biology 2021

  Quote: The polyclonal antibody for GPx-1/2 (sc-30147) was purchased from Santa Cruz Biotechnology ...
• The Slingshot phosphatase 2 is required for acrosome biogenesis during spermatogenesis in mice

  Ke Xu, et al., bioRxiv - Developmental Biology 2022

  Quote: ... mouse anti-LIMK-2 monoclonal antibody (1:100 dilution, sc-365414, Santa Cruz Biotechnology), mouse anti-F-actin monoclonal antibody (1:500 dilution ...
• MYCN driven oncogenesis involves cooperation with WDR5 to activate canonical MYC targets and G9a to repress differentiation genes

  Zhihui Liu, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Two different MYCN antibodies (antibody 1, Santa Cruz, sc-53993; antibody 2, Abcam, ab16898) (4 µg) ...
• Regulation of Oocyte Meiotic Maturation: Unraveling the Interplay between PKA Inhibition and Cdk1 Activation

  Martina Santoni, et al., bioRxiv - Cell Biology 2023

  Quote: ... Erk1/2 (1:2000 each, rabbit, Santa Cruz Biotechnology C-16 and C-14), pT320-pp1 (1:1000 for the detection of the endogenous protein ...
• CCDC32 stabilizes clathrin-coated pits and drives their invagination

  Ziyan Yang, et al., bioRxiv - Cell Biology 2024

  Quote: ... Anti-α-Adaptin 1/2 Antibody (C-8) (Santa Cruz Biotechnology, Catalog #sc-17771) was used in WB to detect AP2 enrichments.
• Dormant replication origin firing links replication stress to whole chromosomal instability in human cancer

  Ann-Kathrin Schmidt, et al., bioRxiv - Cell Biology 2021

  Quote: ... cells were stained with anti-α-tubulin (1:700, B-5-1-2, Santa Cruz, USA, cat no sc-23948), anti-CENP-C (1:1000 ...
• Improved daylight vision following AAV-mediated expression of R9AP in murine rod photoreceptors

  Koji M. Nishiguchi, et al., bioRxiv - Bioengineering 2020

  Quote: ... bovine serum albumin (2 %) 1 hr before being incubated with anti-RGS9 antibody (1:500; Santa Cruz Biotechnology, SantaCruz, CA) for 2 hours at room temperature ...
• DFCP1 is a Regulator of ATGL-mediated Lipid Droplet Lipolysis

  V.A. Ismail, et al., bioRxiv - Cell Biology 2024

  Quote: ... The anti-14-3-3 (133233) and anti-GFP (sc9996) antibodies were obtained from Santa Cruz Biotechnologies ...
• The type 2 diabetes gene product STARD10 is a phosphoinositide binding protein that controls insulin secretory granule biogenesis

  Gaelle R. Carrat, et al., bioRxiv - Cell Biology 2020

  Quote: ... the membrane was incubated 1 h with the horseradish peroxidase conjugated donkey anti-goat IgG (Santa Cruz sc2020; 1/2000 in TBS-T + 3%BSA). After 5 washes of 10 min ...
• The type 2 diabetes gene product STARD10 is a phosphoinositide binding protein that controls insulin secretory granule biogenesis

  Gaelle R. Carrat, et al., bioRxiv - Cell Biology 2020

  Quote: ... in TBS-T and probed for 1 h with the polyclonal goat anti-STARD10 antibody (Santa Cruz sc54336; 1/1000 in TBS-T + 3%BSA). After 5 washes of 10 min ...
• Exploring the Single-Cell Dynamics of FOXM1 Under Cell Cycle Perturbations

  Tooba Jawwad, et al., bioRxiv - Systems Biology 2024

  Quote: ... and CDK1/2 III (CDK1/2; Santa Cruz) were dissolved in DMSO (Sigma ...
• Induction of selective cell death in HIV-1-infected cells by DDX3 inhibitors leads to depletion of the inducible reservoir

  Shringar Rao, et al., bioRxiv - Microbiology 2021

  Quote: ... anti-IRF-3 (sc33641, Santa Cruz), anti BIRC5 (sc17779 ...
• A novel small molecule that induces cytotoxicity in lung cancer cells inhibits disulfide reductases GSR and TXNRD1

  Fraser D. Johnson, et al., bioRxiv - Cancer Biology 2021

  Quote: ... ES936 (Santa Cruz, 192820-78-3), 2-AAPA (Sigma ...
• Dietary zinc restriction induces nociceptive pain with reduced inflammation in mice

  Cleverton Kleiton Freitas de Lima, et al., bioRxiv - Biochemistry 2020

  Quote: ... anti-ATF-3 (Santa Cruz, RRID:AB_2258513), anti-GAP-43 (Santa Cruz ...
• A new strategy for identifying polysialylated proteins reveals they are secreted from cancer cells as soluble proteins and as part of extracellular vesicles

  Carmanah Hunter, et al., bioRxiv - Biochemistry 2022

  Quote: ... α-AGR2/3 (Santa Cruz sc-376653), α-G6PD (Santa Cruz sc-373886) ...
• The cytidine deaminase APOBEC3A is required for large ribosomal subunit biogenesis

  Mason A. McCool, et al., bioRxiv - Molecular Biology 2023

  Quote: ... α3-HRP (Santa Cruz, sc-126), α romycin (Kerafast ...
• CTPS1 inhibition synergizes with replication stress signaling inhibition in MYC-amplified Group 3 medulloblastoma

  Matthew R Hathaway, et al., bioRxiv - Cancer Biology 2024

  Quote: ... 3-Deazuridine (Santa Cruz Biotechnology, 394445) was diluted in corn oil (Millipore Sigma ...
• Machine learning-based classification of binary dynamic fluorescence signals reveals muscle stem cell fate transitions in response to pro-regenerative niche factors

  Matteo Togninalli, et al., bioRxiv - Cell Biology 2022

  Quote: ... and then cells were stained with rabbit cleaved caspase-3 primary antibody (Santa Cruz Biotechnology, sc-7148, 1:200) and Alexa Fluor 647-conjugated goat anti-rabbit IgG secondary antibody (Jackson Immunoresearch Laboratories ...
• Sensory neurons safeguard from mutational inheritance by controlling the CEP-1/p53-mediated DNA damage response in primordial germ cells

  Simon Uszkoreit, et al., bioRxiv - Genetics 2022

  Quote: ... 1:10000 dilution (PGL-3 antibody was generously provided by Prof. Susan Strome, University of California Santa Cruz, USA) and the slides were incubated in the humid chamber at 4°C overnight ...
• Single-molecule live imaging of subunit interactions and exchange within cellular regulatory complexes

  Thomas G.W. Graham, et al., bioRxiv - Molecular Biology 2024

  Quote: ... membranes were probed for approximately 3 h with 1:1000 dilutions of goat anti-CycT1 (Santa Cruz #sc-8127) or rabbit anti-HEXIM1 (Bethyl A303-112A) ...
• Pharmacological CDK4/6 inhibition unravels a p53-induced secretory phenotype in senescent cells

  Boshi Wang, et al., bioRxiv - Cell Biology 2020

  Quote: ... Polybrene (6 μg/ml; cat# sc-134220, Santa Cruz Biotechnology) was added together with the lentiviral particles to enhance the infection efficiency ...
• SFI1 and centrin form a distal end complex critical for proper centriole architecture and ciliogenesis

  Imène B. Bouhlel, et al., bioRxiv - Cell Biology 2021

  Quote: ... HsSAS-6 (sc-81431, sc-98506 Santa Cruz Biotechnology, Inc.), STIL (A302-441A-T ...