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101 - 150 of 7988 citations for 3 Methyl 1 6 naphthyridine 2 carboximidamide hydrochloride since 2020

• Zinc-based Ultrasensitive Microscopic Barrier Assay (ZnUMBA): a live-imaging method for detecting epithelial barrier breaches with spatiotemporal precision

  Tomohito Higashi, et al., bioRxiv - Cell Biology 2022

  Quote: ... mouse anti-cingulin mAb (clone G-6; sc-365264) and goat anti-ZO-3 pAb (C-17; sc-11478) were from Santa Cruz Biotechnology (CA ...
• A critical role for E2-p53 interaction during the HPV16 life cycle

  Christian T. Fontan, et al., bioRxiv - Molecular Biology 2021

  Quote: ... (monoclonal B9)(71) Cellular DNA was stained with 4’,6-diamidino-2-phenylindole (DAPI, Santa Cruz sc-3598). Microscopy was performed using the Keyence imaging system,
• The role of actin and myosin II in the cell cortex of adhered and suspended cells

  D.A.D. Flormann, et al., bioRxiv - Biophysics 2021

  Quote: ... The primary antibodies used for the immunostaining were mouse monoclonal antibodies (Arp3 [A-1], sc-48344; formin 2 [C-3], sc-376787; Santa Cruz Biotechnology, Dallas, Texas, USA). The primary antibodies were diluted 1:200 in 3% BSA and left in contact with the cells for 1 h at room temperature ...
• Systematic analysis of ADP-ribose detection reagents and optimisation of sample preparation to detect ADP-ribosylation in vitro and in cells

  Lisa Weixler, et al., bioRxiv - Molecular Biology 2022

  Quote: ... anti-tubulin 1:5000 (B-5-1-2 Santa Cruz). For slot blotting ...
• Polymorphic KIR3DL3 expression modulates tissue-resident and innate-like T cells

  William H. Palmer, et al., bioRxiv - Immunology 2022

  Quote: ... or SHP-2 (B-1; Santa Cruz Biotechnology; 1:1000). Membranes were washed five times in TBST ...
• Mitochondrial uncoupling protein 2 (UCP2), but not UCP3, is sensitive to oxygen concentration in cells

  Karolina E. Hilse, et al., bioRxiv - Cell Biology 2020

  Quote: ... Oct 3/4 (Santa Cruz, sc-9081, dilution 1:1500), and VDAC (voltage-dependent anion channel ...
• SUMOylation- and GAR1-dependent regulation of dyskerin nuclear and subnuclear localization

  D.E. MacNeil, et al., bioRxiv - Cell Biology 2020

  Quote: ... or mouse anti-dyskerin (Santa Cruz H-3, 1:25) in PBG (1% cold fish water gelatin ...
• Lin28a rejuvenates muscle stem cells via mitochondrial optimization

  Peng Wang, et al., bioRxiv - Cell Biology 2021

  Quote: ... citrate synthase (G-3) (sc-390693; Santa Cruz ; 1:1000).
• The adenoviral E1B-55k protein present in HEK293 cells mediates abnormal accumulation of key WNT signaling proteins in large cytoplasmic aggregates

  Petter Angell Olsen, Stefan Krauss, bioRxiv - Cell Biology 2021

  Quote: ... APC (F-3) (Santa Cruz Biotechnology; sc-9998; 1:50), DVL2 (10B5 ...
• Klebsiella pneumoniae reduces SUMOylation to limit host defence responses

  Joana Sá-Pessoa, et al., bioRxiv - Microbiology 2020

  Quote: ... anti-SUMO2/3 (1:1000, Santa Cruz Biotechnology sc-32873), anti-Ubc9 (1:1000 ...
• The transcription regulator Lmo3 is required for cell fate specification in the external globus pallidus

  Shiona Biswas, et al., bioRxiv - Neuroscience 2022

  Quote: ... and rabbit anti-phosphoHistone 3 (1:250; Santa Cruz Biotechnology). Alexa Fluor conjugated secondary antibodies (Molecular probes ...
• miR-183/96/182 cluster is an important morphogenetic factor targeting PAX6 expression in differentiating human retinal organoids

  Lucie Peskova, et al., bioRxiv - Molecular Biology 2020

  Quote: ... or Oct-3/4 (sc-5279, Santa Cruz, 1:400). The cells were then washed and incubated with secondary antibodies antiRabbit or anti-Mouse AlexaFluor 488 (Thermo Fisher Scientific ...
• Organic Dust Exposure Induces Stress Response and Mitochondrial Dysfunction in Monocytic Cells

  Sanjana Mahadev-Bhat, et al., bioRxiv - Cell Biology 2020

  Quote: ... Caspase 1 and Caspase 3 was purchased from Santa Cruz Biotechnology ...
• SUMOylation- and GAR1-dependent regulation of dyskerin nuclear and subnuclear localization

  D.E. MacNeil, et al., bioRxiv - Cell Biology 2020

  Quote: ... anti-His (Santa Cruz, sc-8036, H-3, 1:500), and anti-alpha tubulin (Sigma ...
• SUMOylation- and GAR1-dependent regulation of dyskerin nuclear and subnuclear localization

  D.E. MacNeil, et al., bioRxiv - Cell Biology 2020

  Quote: ... anti-dyskerin (Santa Cruz, sc-373956, H-3, 1:1500), anti-GAR1 (Proteintech ...
• A chemical probe to modulate human GID4 Pro/N-degron interactions

  Dominic D.G Owens, et al., bioRxiv - Molecular Biology 2023

  Quote: ... SAP62 (1:1000; A-3, sc-390444, Santa Cruz Biotechnology), Muskelin (C-12 ...
• MRCK controls myosin II activation in the polarized cortex of mouse oocytes and promotes spindle rotation and male pronucleus centration

  Anne Bourdais, Benoit Dehapiot, Guillaume Halet, bioRxiv - Cell Biology 2022

  Quote: ... MRCKα (B-3) (1:100; Santa Cruz Biotechnology sc-374568), MRCKβ (A-2 ...
• Early mitochondrial dysfunction proceeds neuroinflammation, synaptic alteration, and autophagy impairment in hippocampus of App knock-in Alzheimer mouse models

  Luana Naia, et al., bioRxiv - Neuroscience 2023

  Quote: ... β3 tubulin (1:2,000) (Santa cruz, Cat. no. sc-80016). After washing with TBS-T for three times ...
• Targeting the deNEDDylating enzyme NEDP1 to ameliorate ALS phenotypes through Stress Granules dissolution

  Toufic Kassouf, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse anti-TIA-1 (G-3) (#sc-166247, Santa cruz), mouse anti-eIF4G (A-10 ...
• TRiPPing the sensors: The osmosensing pathway of Polycystin 2

  K.M. Márquez-Nogueras, et al., bioRxiv - Physiology 2023

  Quote: ... PC2 (D-3, 1:500, sc-28331; Santa Cruz Biotechnology), MAP4 (1:1000 ...
• Loss of TMEM106B exacerbates Tau pathology and neurodegeneration in PS19 mice

  Tuancheng Feng, Huan Du, Fenghua Hu, bioRxiv - Neuroscience 2023

  Quote: ... mouse anti-acetylated alpha Tubulin Antibody (6-11B-1) (Santa Cruz, sc-23950), mouse anti-acetylated Tubulin (Lys40 ...
• An Aurora kinase A-BOD1L1-PP2A B56 Axis promotes chromosome segregation fidelity

  Thomas J. Kucharski, et al., bioRxiv - Cell Biology 2024

  Quote: ... mouse anti-PP2A B56 Beta (Santa Cruz E-6; IB at 1:500), mouse anti-PP2A B56 Gamma (Santa Cruz A-11 ...
• Master corepressor inactivation through multivalent SLiM-induced polymerization mediated by the oncogene suppressor RAI2

  Nishit Goradia, et al., bioRxiv - Molecular Biology 2024

  Quote: ... HSC70 protein (clone B-6; Santa Cruz Biotechnology, CA, USA, dilution 1:106) was used as a loading control and HRP-(Cell Signaling Technology ...
• A kinetochore-centrosome feedback loop linking CENP-E and Aurora kinases controls chromosome biorientation and congression

  Kruno Vukušić, Iva M. Tolić, bioRxiv - Cell Biology 2024

  Quote: ... mouse monoclonal anti-KIFC1 (M-6, sc-100947, Santa Cruz, diluted 1:500), rabbit polyclonal anti-Kif18a (A301-080A ...
• Recording large-scale, cellular-resolution neuronal activity from freely-moving mice

  Aniruddha Das, et al., bioRxiv - Neuroscience 2022

  Quote: ... and injected with Chlorprothixene Hydrochloride (IM, 30 µl of 0.33 mg/ml solution, Santa Cruz). PC of the CaMPARI2 signal started at least 30 min after the Chlorprothixene Hydrochloride injection ...
• Dual targeting of MAPK and PI3K pathways unlocks redifferentiation of Braf-mutated thyroid cancer organoids

  Hélène Lasolle, et al., bioRxiv - Cancer Biology 2023

  Quote: ... ERK1/2 (1:400; Santa Cruz Biotechnology), and β-Actin (1:1,1000 ...
• Extracellular communication between brain cells through functional transfer of Cre mRNA

  David Rufino-Ramos, et al., bioRxiv - Cell Biology 2023

  Quote: ... Lamp-2 (Santa Cruz, sc18822, 1:1000), TSG101 (BD Biosciences BD612696 ...
• The ANKS3/BICC1 protein complex is a master post-transcriptional regulator of NPHP1 ciliopathy-gene transcripts

  Alexia Mahuzier, et al., bioRxiv - Pathology 2024

  Quote: ... Polycystin-2 (Santa Cruz, SC10376, 1:50), NPHP1-C20 (Santa Cruz ...
• Adducin Regulates Sarcomere Disassembly During Cardiomyocyte Mitosis

  Feng Xiao, et al., bioRxiv - Cell Biology 2020

  Quote: ... anti-Filamin 1 (E-3, sc-17749, Santa Cruz, 1:100, for Figure 1F), anti-α-adducin (phospho T445 ...
• Binding of CEP152 to PLK4 stimulates kinase activity to promote centriole assembly

  Hazal Kübra Gürkaşlar, Ingrid Hoffmann, bioRxiv - Cell Biology 2024

  Quote: ... mouse anti-ninein (1:1000 IF; F5), mouse anti-SAS-6 (1:500 IF, 1:100 U-ExM) from Santa Cruz Biotechnology ...
• Dynein acts to cluster glutamate receptors and traffic the PIP5 kinase, Skittles, to regulate postsynaptic membrane organization at the neuromuscular junction

  Amanda L. Neisch, et al., bioRxiv - Cell Biology 2021

  Quote: ... mouse anti acetylated α-tubulin 6-11B-1 Alexa488 conjugated 1:50 (Santa Cruz Biotechnology, Inc., Dallas, TX), mouse anti-Dhc64c P1H4 at 1:400 (McGrail and Hays ...
• The adenoviral E1B-55k protein present in HEK293 cells mediates abnormal accumulation of key WNT signaling proteins in large cytoplasmic aggregates

  Petter Angell Olsen, Stefan Krauss, bioRxiv - Cell Biology 2021

  Quote: ... Tankyrase-1/2 (E10) (Santa Cruz Biotechnology; sc-365897; 1:40), AXIN1 (C76H11 ...
• Quantification of extracellular vesicles with unaltered surface membranes using an internalized oligonucleotide tracer and droplet digital PCR applied to modeling of in vivo kinetics

  Thomas De Luca, et al., bioRxiv - Molecular Biology 2020

  Quote: ... anti-eIF2C (Argonaute1-4; clone B-3, 2 μg/mL, cat. no. sc-376696, Santa Cruz Biotechnology), anti-hnRNP A2/B1 (clone b-7 ...
• Mechanisms of A-type lamin targeting to nuclear ruptures are disrupted in LMNA- and BANF1-associated progerias

  Rhiannon M. Sears, Kyle J. Roux, bioRxiv - Cell Biology 2022

  Quote: ... for 2-3 d for pBabe puro plasmid or G418 sulfate (30 μg/ml; Santa Cruz Biotechnology) for 5–7 d for pBabe neo plasmids for selection of viral integration ...
• Genome-wide Screens Identify Lineage- and Tumor Specific-Genes Modulating MHC-I and MHC-II Immunosurveillance in Human Lymphomas

  Devin Dersh, et al., bioRxiv - Cancer Biology 2020

  Quote: ... anti-14-3-3 (Santa Cruz).
• SOD2 in Skeletal Muscle: New Insights from an Inducible Deletion Model

  Aowen Zhuang, et al., bioRxiv - Physiology 2021

  Quote: ... pan 14-3-3 (Santa Cruz), phospho-T172 AMPKalpha (Cell Signaling) ...
• Loss of CLN3 in microglia leads to impaired lipid metabolism and myelin turnover

  Seda Yasa, et al., bioRxiv - Neuroscience 2024

  Quote: ... anti-Galectin 3 (WB: 1:500, Santa Cruz Biotech sc-32790), anti-PDI (IF ...
• Phase-specific signatures of wound fibroblasts and matrix patterns define cancer-associated fibroblast subtypes

  Mateusz S. Wietecha, et al., bioRxiv - Genomics 2022

  Quote: ... or 3) goat anti-fibronectin (1:200; Santa Cruz; #sc-6953) and rabbit anti-MFAP4 (1:100 ...
• Distinctive chaperonopathy in skeletal muscle associated with the dominant variant in DNAJB4

  Michio Inoue, et al., bioRxiv - Neuroscience 2022

  Quote: ... sections were probed with caveolin-3 (Santa Cruz Biotechnology, 1:100) followed by appropriate secondary antibodies ...
• NRF2 connects Src tyrosine kinase to ferroptosis resistance in glioblastoma

  Claudia Cirotti, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-Heme Oxygenase 1 (A-3) (sc-136960, Santa Cruz Biotechnology), anti-NQO1 (A-180 ...
• Loss of SPNS1, a lysosomal transporter, in the nervous system causes dysmyelination and white matter dysplasia

  Yoshinobu Ichimura, et al., bioRxiv - Cell Biology 2024

  Quote: ... and GALECTIN-3 (sc-23938, Santa Cruz Biotechnology Inc.; 1:200) were used as primary antibodies ...
• A catalytic-independent function of human DNA polymerase Kappa controls the pool of the Checkpoint Kinase 1

  Marina Dall’Osto, et al., bioRxiv - Cell Biology 2021

  Quote: ... ORC2 (MBL M055-3 - 1/1000), ORC4 (Transduction laboratories H83120, 1/500) MCM7 (Santa Cruz sc22782 - 1/1000), MCM2 (Abcam ab4461 - 1/2000) ...
• CEBPA restricts alveolar type 2 cell plasticity during development and injury-repair

  Dalia Hassan, Jichao Chen, bioRxiv - Developmental Biology 2023

  Quote: ... rabbit anti-NK homeobox 2-1 (NKX2-1, 1:1000, sc-13040, Santa Cruz), rabbit anti-pro-surfactant protein C (SFTPC ...
• Fatty acid binding protein 5 forms higher order assemblies with FLAP or COX-2 in LPS-stimulated macrophages

  Shelby E. Elder, et al., bioRxiv - Cell Biology 2020

  Quote: ... and anti-COX-2 (Santa Cruz, 1:100) were diluted in blocking solution overnight at 4 °C ...
• The N-terminus of GPR37L1 is proteolytically processed by matrix metalloproteases

  James L. J. Coleman, et al., bioRxiv - Biochemistry 2020

  Quote: ... TAPI-1 and TAPI-2 (Santa Cruz Biotechnology), and TIMP1 ...
• Astroglial exosome HepaCAM signaling and ApoE antagonization coordinates early postnatal cortical pyramidal neuronal axon growth and dendritic spine formation

  Shijie Jin, et al., bioRxiv - Neuroscience 2023

  Quote: ... TSG101 (1:100, clone C-2 Santa Cruz), GFAP (1:2000 ...
• Bioengineered human colon organoids with in vivo-like complexity and function

  Olga Mitrofanova, et al., bioRxiv - Bioengineering 2023

  Quote: ... mucin 2 (1:50, Santa Cruz sc-7314), chromogranin-A (1:100 ...
• P-TEFb promotes cell survival upon p53 activation by suppressing intrinsic apoptosis pathway

  Zhijia Wang, et al., bioRxiv - Biochemistry 2022

  Quote: ... Anti-IRS-2 (Santa Cruz Biotechnology, 1:1000); anti-phospho-Akt (Ser473 ...
• ACE-2 Blockade & TMPRSS2 Inhibition Mitigate SARS-CoV-2 Severity Following Cigarette Smoke Exposure in Airway Epithelial Cells In Vitro

  Shah S Hussain, et al., bioRxiv - Cell Biology 2024

  Quote: ... or ACE-2 (1:100, ab15348, Santa Cruz). Negative controls were produced by eliminating the primary antibodies from the diluents ...
• How scars shape the neural landscape: key molecular mediators of TGF-β1’s anti-neuritogenic effects

  Kye-Im Jeon, Krystel R. Huxlin, bioRxiv - Neuroscience 2020

  Quote: ... and a mouse monoclonal antibody to acetylated α-tubulin (Ac-Tub; 1:5000, 6-11B-1, Santa Cruz Biotechnology). Responsiveness to NGF was assayed by probing for the expression of tropomyosin receptor kinase A (Trk-A ...