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2851 - 2900 of 8862 citations for 6 1 4 dioxa 8 azaspiro 4.5 decan 8 yl 3 hydroxy 2 iminopyrimidin 4 amine since 2019

• Bach2 is a potent repressor of Nrf2-mediated antioxidant enzyme expression in dopaminergic neurons

  Elisa A. Waxman, bioRxiv - Neuroscience 2019

  Quote: ... Nrf2 (1:250; Santa Cruz, H-300), tyrosine hydroxylase (TH ...
• Differential Expression of the T cell Inhibitor TIGIT in Glioblastoma and Multiple Sclerosis

  Liliana E. Lucca, et al., bioRxiv - Immunology 2019

  Quote: ... TIGIT (Santa Cruz sc-103349, 1:800), CD226 (Novus Biologicals NBP1-85001 ...
• Inhibitor of Differentiation 4 (ID4) represses myoepithelial differentiation of mammary stem cells through its interaction with HEB

  Holly Holliday, et al., bioRxiv - Developmental Biology 2020

  Quote: ... V5 (1:200, Santa Cruz sc-58052). Following washing ...
• Cables2 Is a Novel Smad2-Regulatory Factor Essential for Early Embryonic Development in Mice

  Tra Thi Huong Dinh, et al., bioRxiv - Developmental Biology 2019

  Quote: ... and PARP-1 (sc-8007, Santa Cruz).
• C/EBPδ demonstrates a dichotomous role in tumor initiation and promotion of epithelial carcinoma

  Ramlogan Sowamber, et al., bioRxiv - Cancer Biology 2019

  Quote: ... SIP1 (Santa Cruz, sc-48789, 1/200), Twist (Santa cruz ...
• C/EBPδ demonstrates a dichotomous role in tumor initiation and promotion of epithelial carcinoma

  Ramlogan Sowamber, et al., bioRxiv - Cancer Biology 2019

  Quote: ... Twist (Santa cruz, sc-81417, 1/500) and goat HRP-IgG (anti-mouse or anti-rabbit ...
• GC content shapes mRNA decay and storage in human cells

  Maïté Courel, et al., bioRxiv - Molecular Biology 2019

  Quote: ... anti-Pol II (1:100, Santa Cruz).
• Arp2/3 complex-driven spatial patterning of the BCR enhances immune synapse formation, BCR signaling and cell activation

  Madison Bolger-Munro, et al., bioRxiv - Immunology 2019

  Quote: ... actin (Santa Cruz, #sc-47778; 1:5000), or CD79a ((Gold et al. ...
• Bone-targeted lncRNA OGRU alleviates unloading-induced bone loss via miR-320-3p/Hoxa10 axis

  Ke Wang, et al., bioRxiv - Molecular Biology 2019

  Quote: ... and Hoxa10 (1:1000, Santa Cruz, USA) in primary antibody dilution buffer (Beyotime ...
• Bone-targeted lncRNA OGRU alleviates unloading-induced bone loss via miR-320-3p/Hoxa10 axis

  Ke Wang, et al., bioRxiv - Molecular Biology 2019

  Quote: ... or Hoxa10 (1:100, Santa Cruz, USA). Sections were examined with a microscope (Eclipse E100 ...
• AMPKα1 is essential for Glucocorticoid Receptor triggered anti-inflammatory macrophage activation

  Giorgio Caratti, et al., bioRxiv - Physiology 2020

  Quote: ... CD206 (Santa Cruz, sc-58987, 1:50), CD163 (Santa Cruz ...
• IMPDH inhibitors for anti-tumor therapy in tuberous sclerosis complex

  Alexander J. Valvezan, et al., bioRxiv - Cancer Biology 2019

  Quote: ... ADK (Santa Cruz #sc-514588, 1:500), phospho-Chk1 S345 (CST #2348) ...
• High-phytate/low-calcium diet is a risk factor for crystal nephropathies, renal phosphate wasting, and bone loss

  Ok-Hee Kim, et al., bioRxiv - Physiology 2019

  Quote: ... NHERF1 (A-7, 1:200; Santa Cruz), and SLC34A1 (ab182099 ...
• Components of the endocytic and recycling trafficking pathways interfere with the integrity of the Legionella-containing vacuole

  Ila S. Anand, Won Young Choi, Ralph R. Isberg, bioRxiv - Microbiology 2019

  Quote: ... or GAPDH (Santa Cruz Biotechnology, 1:1000) in 4% milk/TBST ...
• Cohesin promotes stochastic domain intermingling to ensure proper regulation of boundary-proximal genes

  Jennifer M. Luppino, et al., bioRxiv - Cell Biology 2019

  Quote: ... PCNA (Santa Cruz sc-56, 1:100), CENPF (Novus Biologicals NB500-101 ...
• Cohesin promotes stochastic domain intermingling to ensure proper regulation of boundary-proximal genes

  Jennifer M. Luppino, et al., bioRxiv - Cell Biology 2019

  Quote: ... NIPBL (Santa Cruz sc-374625, 1:400), WAPL (Santa Cruz sc-365189 ...
• Cohesin promotes stochastic domain intermingling to ensure proper regulation of boundary-proximal genes

  Jennifer M. Luppino, et al., bioRxiv - Cell Biology 2019

  Quote: ... WAPL (Santa Cruz sc-365189, 1:250), Histone H3 (Abcam ab1791 ...
• Loss of SHMT2 mediates 5-FU chemoresistance by inducing autophagy in colorectal cancer

  Jian Chen, et al., bioRxiv - Cancer Biology 2019

  Quote: ... p53 (DO-1, Santa Cruz; ab32389, Abcam) and actin (A1978 ...
• TDP-43 regulates the expression levels of Disc-large in skeletal muscles to promote the assemble of the neuromuscular synapses in Drosophila

  Nina Strah, et al., bioRxiv - Neuroscience 2019

  Quote: ... anti-GAPDH (#SC25778 Santa Cruz 1:2000). Secondary antibodies ...
• Astrocyte senescence in an Alzheimer’s disease mouse model is mediated by TGF-β1 and results in neurotoxicity

  Shoshik Amram, et al., bioRxiv - Neuroscience 2019

  Quote: ... p21 (1:1000, Santa Cruz, #sc-6246), vascular endothelial growth factor (VEGF ...
• Astrocyte senescence in an Alzheimer’s disease mouse model is mediated by TGF-β1 and results in neurotoxicity

  Shoshik Amram, et al., bioRxiv - Neuroscience 2019

  Quote: ... p65 (1:1000, Santa Cruz, #sc-372), brain-derived neurotrophic factor (BDNF ...
• Gli3 regulates vomeronasal neurogenesis, olfactory ensheathing cell formation and GnRH-1 neuronal migration

  Ed Zandro M. Taroc, et al., bioRxiv - Developmental Biology 2019

  Quote: ... mouse -α-GAD67 (1:200, Santa Cruz), goat-α-AP-2ε (1:1000 ...
• Gli3 regulates vomeronasal neurogenesis, olfactory ensheathing cell formation and GnRH-1 neuronal migration

  Ed Zandro M. Taroc, et al., bioRxiv - Developmental Biology 2019

  Quote: ... mouse-α-Meis2 (1:500, Santa Cruz), rabbit-α-phospho-Histone-H3 (1:400 ...
• Gli3 regulates vomeronasal neurogenesis, olfactory ensheathing cell formation and GnRH-1 neuronal migration

  Ed Zandro M. Taroc, et al., bioRxiv - Developmental Biology 2019

  Quote: ... goat-α-Sox10 (1:100, Santa Cruz), goat-α-collagen IV (1:800 ...
• Hypusinated eIF5A is expressed in pancreas and spleen of individuals with type 1 and type 2 diabetes

  Teresa L. Mastracci, et al., bioRxiv - Cell Biology 2019

  Quote: ... goat anti-ghrelin (Santa Cruz; 1:500), mouse anti-Pax5 (DAKO ...
• Drosophila ovarian germline stem cell cytocensor projections dynamically receive and attenuate BMP signaling

  Scott G. Wilcockson, Hilary L. Ashe, bioRxiv - Developmental Biology 2019

  Quote: ... Rb anti-Vasa (Santa Cruz, 1:500). Secondary antibodies and other stains used were Alexa Fluor 488 Donkey anti-Rb ...
• ASCL1 represses a latent osteogenic program in small cell lung cancer in multiple cells of origin

  Rachelle R. Olsen, et al., bioRxiv - Cancer Biology 2020

  Quote: ... MYC (sc-764, Santa Cruz, 1:150), NEUROD1 (ab109224 ...
• A functional pre-screening platform for identifying points of vulnerability in the cell death map of human melanoma tumors

  Naama Pnina Dekel-Bird, et al., bioRxiv - Cancer Biology 2020

  Quote: ... or Mcl-1 (Santa Cruz, sc-20679). Detection was done with either HRP-conjugated goat anti-mouse or anti-rabbit secondary antibodies (Jackson ImmunoResearch cat#211-032-171 ...
• Discovery of ciliary G protein-coupled receptors regulating pancreatic islet insulin and glucagon secretion

  Chien-Ting Wu, et al., bioRxiv - Physiology 2020

  Quote: ... PTGER4 (Santa Cruz, sc-55596, 1:100), KISS1R (A kindly gift from Professor Kirk Mykytyn ...
• Discovery of ciliary G protein-coupled receptors regulating pancreatic islet insulin and glucagon secretion

  Chien-Ting Wu, et al., bioRxiv - Physiology 2020

  Quote: ... FFAR4 (Santa Cruz, sc-390752, 1:100), Acetylated tubulin (Sigma ...
• Tousled-like kinase activity is required for transcriptional silencing and suppression of innate immune signaling

  Sandra Segura-Bayona, et al., bioRxiv - Molecular Biology 2019

  Quote: ... CtIP (Santa Cruz sc-271339, 1:500); BLM (Abcam ab2179 ...
• Tousled-like kinase activity is required for transcriptional silencing and suppression of innate immune signaling

  Sandra Segura-Bayona, et al., bioRxiv - Molecular Biology 2019

  Quote: ... MRE11 (Santa Cruz sc-135992, 1:200); CtIP (Santa Cruz sc-271339 ...
• Mitotic spindle assembly is controlled by the APC/C localized at the centrosome

  Thomas Tischer, Jing Yang, David Barford, bioRxiv - Cell Biology 2020

  Quote: ... Cdc20 (Santa Cruz sc-8358, 1:100), Bub3 (BD 811730 ...
• Discovery and 3D imaging of a novel ΔNp63-expressing basal cell type in human pancreatic ducts with implications in disease

  Sandrina Martens, et al., bioRxiv - Pathology 2020

  Quote: ... HNF1β (1/100, sc-7411, Santa Cruz), PDX1 (1/100 ...
• Intraflagellar transport complex B proteins regulate the Hippo effector Yap1 during cardiogenesis

  Marina Peralta, et al., bioRxiv - Developmental Biology 2019

  Quote: ... Yap1 (Santa Cruz sc-101199, 1:100), Amotl1 (Sigma HPA001196 ...
• Intraflagellar transport complex B proteins regulate the Hippo effector Yap1 during cardiogenesis

  Marina Peralta, et al., bioRxiv - Developmental Biology 2019

  Quote: ... Wt1 (Santa Cruz sc-192, 1:50), Yap1 (Santa Cruz sc-101199 ...
• Noncanonical scaffolding of G_αi and β-arrestin by G protein-coupled receptors

  Jeffrey S. Smith, et al., bioRxiv - Cell Biology 2019

  Quote: ... Galpha i-1 (13533, Santa Cruz Biotechnology), Galpha q/11/14 (365906 ...
• CircHIPK3 dysregulation of the miR-30c/DLL4 axis is essential for KSHV lytic replication

  Katherine L. Harper, et al., bioRxiv - Microbiology 2021

  Quote: ... ORF57 (Santa Cruz sc-135747 1/1000), GAPDH (Proteintech 60004-1-Ig 1/5000) ...
• miR-183/96/182 cluster is an important morphogenetic factor targeting PAX6 expression in differentiating human retinal organoids

  Lucie Peskova, et al., bioRxiv - Molecular Biology 2020

  Quote: ... SOX2 (sc-365823, Santa Cruz, 1:1000), SOX1 (bs-12276R ...
• Phosphorylation of pericyte FAK-Y861 affects tumour cell apoptosis and tumour blood vessel regression

  Delphine M. Lees, et al., bioRxiv - Cancer Biology 2020

  Quote: ... endomucin (V7.C7, Santa Cruz, 1:1000). The anti-HSC70 (Santa Cruz ...
• Makorin 1 controls embryonic patterning by alleviating Bruno1-mediated repression of oskar translation

  Annabelle Dold, et al., bioRxiv - Developmental Biology 2019

  Quote: ... mouse α-ubiquitin (1:1000; Santa Cruz) Fab α-pAbp (2.5 µg in 5 ml) ...
• Fragile X Mental Retardation Protein regulates R-loop formation and prevents global chromosome fragility

  Arijita Chakraborty, et al., bioRxiv - Genomics 2019

  Quote: ... anti-UGT1A (Santa Cruz Biotechnology, 1:250), anti-CYP2C9 (Invitrogen ...
• Fate of developmental mechanisms of myocardial plasticity in the postnatal heart

  Konstantinos E. Hatzistergos, et al., bioRxiv - Developmental Biology 2019

  Quote: ... Nkx2.5 (1:50, Santa Cruz Biotechnologies, #SC8697), cardiac troponin-T (1:200 ...
• PRSS2 stimulates tumor growth by remodeling the TME via repression of Tsp1

  Lufei Sui, et al., bioRxiv - Cancer Biology 2021

  Quote: ... p53 (DO-1 mouse mAb, Santa Cruz), LRP1 (rabbit pAb ...
• Human Induced Pluripotent Stem Cell Derived Sensory Neurons are Sensitive to the Neurotoxic Effects of Paclitaxel

  Chenling Xiong, et al., bioRxiv - Pharmacology and Toxicology 2020

  Quote: ... goat anti-Peripherin (1:500, Santa Cruz), pig anti-TRPV1 (1:200 ...
• Human Induced Pluripotent Stem Cell Derived Sensory Neurons are Sensitive to the Neurotoxic Effects of Paclitaxel

  Chenling Xiong, et al., bioRxiv - Pharmacology and Toxicology 2020

  Quote: ... goat anti-SOX10 (1:500, Santa Cruz), mouse anti-BRN3A (1:500 ...
• Serine 165 Phosphorylation of SHARPIN regulates the Activation of NF-κB

  An Thys, et al., bioRxiv - Immunology 2020

  Quote: ... HOIL-1 ((sc-393754, Santa Cruz Biotechnology) and linear ubiquitin ...
• Senolytic activity of small molecular polyphenols from olive restores chondrocyte redifferentiation and cartilage regeneration in osteoarthritis

  Marta Varela-Eirín, et al., bioRxiv - Cell Biology 2019

  Quote: ... Twist-1 (Santa Cruz Biotechnology, sc-81417), CD166 (Santa Cruz Biotechnology ...
• DRP1-mediated regulation of mitochondrial dynamics determines the apoptotic response upon embryonic differentiation

  Barbara Pernaute, et al., bioRxiv - Developmental Biology 2019

  Quote: ... anti-Bad (Santa Cruz Biotechnology, 1/500), anti-Bax N20 (Santa Cruz Biotechnology ...
• DRP1-mediated regulation of mitochondrial dynamics determines the apoptotic response upon embryonic differentiation

  Barbara Pernaute, et al., bioRxiv - Developmental Biology 2019

  Quote: ... anti-Tom20 (Santa Cruz Biotechnologies, 1/1000), anti-Drp1 (Cell Signalling ...