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2701 - 2750 of 8862 citations for 6 1 4 dioxa 8 azaspiro 4.5 decan 8 yl 3 hydroxy 2 iminopyrimidin 4 amine since 2019

• MISTERMINATE Mechanistically Links Mitochondrial Dysfunction with Proteostasis Failure

  Zhihao Wu, et al., bioRxiv - Cell Biology 2019

  Quote: ... rabbit anti-TOM20 (1:1,000, Santa Cruz), rabbit anti-BTF3 (1:500 ...
• Macrophage mediated recognition and clearance of Borrelia burgdorferinelicits MyD88-dependent and -independent phagosomal signals that contribute to phagocytosis and inflammation

  Sarah J. Benjamin, et al., bioRxiv - Immunology 2019

  Quote: ... anti-MyD88 (Santa Cruz 11356, 1:100), anti-TLR2 (eBioscience 14-9021-82 ...
• Attenuated Dopamine Receptor Signaling in Nucleus Accumbens Core in a Rat Model of Chemically-Induced Neuropathy

  D.E. Selley, et al., bioRxiv - Pharmacology and Toxicology 2019

  Quote: ... D1R (Santa Cruz SC 14001; 1:250).
• The Atypical Cyclin-Like Protein Spy1 Overrides p53-Mediated Tumour Suppression and Promotes Susceptibility to Breast Tumorigenesis

  Bre-Anne Fifield, et al., bioRxiv - Cancer Biology 2019

  Quote: ... PCNA (1:500; sc-9857; Santa Cruz), and cleaved-caspase 3 (1:250 ...
• Apolipoprotein E isoform-specific phase transitions in the retinal pigment epithelium drive disease phenotypes in age-related macular degeneration

  Nilsa La Cunza, et al., bioRxiv - Neuroscience 2020

  Quote: ... TOM20 (Santa Cruz sc-11415, 1:200) and ApoE (Genetex GTX100053 1:200) ...
• Expression and distribution of Trophoblast Glycoprotein in the mouse retina

  Colin M Wakeham, Gaoying Ren, Catherine W Morgans, bioRxiv - Neuroscience 2019

  Quote: Mouse anti-calretinin (1:25; Santa Cruz Biotechnology ...
• Regulation of the 20S proteasome by a novel family of inhibitory proteins

  Maya A Olshina, et al., bioRxiv - Biochemistry 2019

  Quote: ... anti-RhoA (1:200, sc418, Santa Cruz), anti-RBBP9 (1:1000 ...
• Regulation of the 20S proteasome by a novel family of inhibitory proteins

  Maya A Olshina, et al., bioRxiv - Biochemistry 2019

  Quote: ... anti-NRas (1:200, sc31, Santa Cruz), anti-DJ-1 (1:10,000 ...
• Regulation of the 20S proteasome by a novel family of inhibitory proteins

  Maya A Olshina, et al., bioRxiv - Biochemistry 2019

  Quote: ... anti-PGDH (1:200, sc271418, Santa Cruz), anti-p53 HRP (1:2500 ...
• XIAP controls RIPK2 signaling by preventing its deposition in speck-like structures

  Kornelia Ellwanger, et al., bioRxiv - Immunology 2019

  Quote: ... anti-Erlin-1 (sc-514820, Santa Cruz), anti Erlin-2 (ABS1610 ...
• Early neuronal processes interact with glia to establish a scaffold for orderly innervation of the cochlea

  N. R. Druckenbrod, et al., bioRxiv - Developmental Biology 2019

  Quote: ... Goat anti-Sox10 (Santa Cruz; 1:500), Rabbit anti-Tuj (Biolegend ...
• Stromal ISLR promotes intestinal regeneration and cancer by suppressing epithelial Hippo signaling

  Jiuzhi Xu, et al., bioRxiv - Cancer Biology 2019

  Quote: ... anti-F4/80 (1:200, Santa Cruz), anti-β-catenin (1:1,000 ...
• Active mode of excretion across digestive tissues predates the origin of excretory organs

  Carmen Andrikou, et al., bioRxiv - Evolutionary Biology 2019

  Quote: ... dilution 1:50 (Biotechnology, Santa Cruz, USA) overnight at 4°C ...
• Enhancement of endothelialization by topographical features is mediated by PTP1B-dependent endothelial adherens junctions remodeling

  Azita Gorji, et al., bioRxiv - Cell Biology 2019

  Quote: ... dilution 1:100 (SC-101199, Santa Cruz); mouse anti-β-catenin ...
• Enhancement of endothelialization by topographical features is mediated by PTP1B-dependent endothelial adherens junctions remodeling

  Azita Gorji, et al., bioRxiv - Cell Biology 2019

  Quote: ... dilution 1:100 (SC-101199, Santa Cruz). Subsequently ...
• Targeted Eicosanoid Profiling Reveals MicroRNA-155 Shifts PGE2/PGD2 Balance Towards Oncogenic State

  Sinae Kim, et al., bioRxiv - Cancer Biology 2020

  Quote: ... anti-PTGDS (1:1000, Santa Cruz Biotechnology), anti-15-PGDH (1:1000 ...
• Targeted Eicosanoid Profiling Reveals MicroRNA-155 Shifts PGE2/PGD2 Balance Towards Oncogenic State

  Sinae Kim, et al., bioRxiv - Cancer Biology 2020

  Quote: ... anti-PTGES2 (1:1000, Santa Cruz Biotechnology), PTGES2 (1:1000 ...
• The zinc finger proteins ZC3H20 and ZC3H21 stabilise mRNAs encoding membrane proteins and mitochondrial proteins in insect-form Trypanosoma brucei

  Bin Liu, Kevin Kamanyi Marucha, Christine Clayton, bioRxiv - Molecular Biology 2019

  Quote: ... ; mouse anti-myc (1:1000 Santa Cruz); mouse anti EP(1:1000 ...
• Cullin-5 adaptor SPSB1 controls NF-κB activation downstream of multiple signalling pathways

  Iliana Georgana, Carlos Maluquer de Motes, bioRxiv - Molecular Biology 2019

  Quote: ... p-p65 (Ser536) (Santa Cruz, 1:500); V5 (BioRad ...
• Pharmacologically diverse antidepressant drugs disrupt the interaction of BDNF receptor TRKB and the endocytic adaptor AP-2

  Senem Merve Fred, et al., bioRxiv - Pharmacology and Toxicology 2019

  Quote: ... AP2M (1:1000, #sc-515920, Santa Cruz), pTRKB.Y515 (1:1000 ...
• C/EBPδ demonstrates a dichotomous role in tumor initiation and promotion of epithelial carcinoma

  Ramlogan Sowamber, et al., bioRxiv - Cancer Biology 2019

  Quote: ... P53 (Santa Cruz; sc-126, 1/500), PAX8 (ProteinTech ...
• A consensus set of genetic vulnerabilities to ATR inhibition

  Nicole Hustedt, et al., bioRxiv - Molecular Biology 2019

  Quote: ... anti-CHK1 (Santa Cruz sc8408, 1:500), anti-pRPA32 (S33 ...
• HNF4 factors control chromatin accessibility and are redundantly required for maturation of the fetal intestine

  Lei Chen, et al., bioRxiv - Developmental Biology 2019

  Quote: ... P63 (Santa Cruz sc-8343, 1:500), BrdU (Bio-Rad MCA2060 ...
• HNF4 factors control chromatin accessibility and are redundantly required for maturation of the fetal intestine

  Lei Chen, et al., bioRxiv - Developmental Biology 2019

  Quote: ... PDGFRα (Santa Cruz sc-338, 1:1000), Cleaved Caspase 3 (Cell Signaling 9661 ...
• Different mutant RUNX1 oncoproteins program alternate haematopoietic differentiation trajectories

  Sophie G Kellaway, et al., bioRxiv - Genomics 2020

  Quote: ... PU.1 antibody (sc-352, Santa Cruz) or GATA1 antibody (ab11852 ...
• Alzheimer’s disease risk gene BIN1 induces Tau-dependent network hyperexcitability

  Yuliya Voskobiynyk, et al., bioRxiv - Neuroscience 2020

  Quote: ... BIN1 (Santa Cruz, sc-30099, 1:500), or LVGCC-β1 (Abcam ...
• Insulin inhibits protein phosphatase 2A to impair β-adrenergic receptor function

  Anita Sahu, et al., bioRxiv - Biochemistry 2020

  Quote: ... anti-PI3Kγ (1:500) (Santa Cruz Biotechnology), anti-GRK2 (1:1000 ...
• Insulin inhibits protein phosphatase 2A to impair β-adrenergic receptor function

  Anita Sahu, et al., bioRxiv - Biochemistry 2020

  Quote: ... anti-GRK2 (1:1000) (Santa Cruz Biotechnology), anti-I2PP2A (1:700 ...
• ASXL3 controls cortical neuron fate specification through extrinsic self-renewal pathways

  BT McGrath, et al., bioRxiv - Neuroscience 2021

  Quote: ... CUX1 (Santa Cruz, sc-13024, 1:150), pH3 (Abcam ...
• Combinatorial small molecule-mediated activation of CBP/p300 with environmental enrichment in chronic severe experimental spinal cord injury to enable axon regeneration and sprouting for functional recovery

  Franziska Mueller, et al., bioRxiv - Neuroscience 2021

  Quote: ... ATF3 (1:100, Santa Cruz, sc-188), pErk (1:250 ...
• The RNA helicases DDX5 and DDX17 facilitate neural differentiation of human pluripotent stem cells NTERA2

  Praewa Suthapot, et al., bioRxiv - Neuroscience 2021

  Quote: ... and TUBB3 (Santa Cruz, 1:150 dilution). Cells were analyzed with a fluorescence microscope (Olympus ...
• Alterations in leptin signaling in Amyotrophic Lateral Sclerosis (ALS)

  Agueda Ferrer-Donato, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-Akt (1:1000 Santa Cruz); mouse anti-STAT3 (1:1000 ...
• Cerebral organoid model reveals excessive proliferation of human caudal late interneuron progenitors in Tuberous Sclerosis Complex

  Oliver L. Eichmüller, et al., bioRxiv - Neuroscience 2020

  Quote: ... and 1 mM db-cAMP (Santa Cruz). Gradual transfer from HN+A to LN was performed as follows with feedings performed every third day ...
• COUP-TFI regulates diameter of the axon initial segment in the mammalian neocortex

  Xuanyuan Wu, et al., bioRxiv - Neuroscience 2020

  Quote: ... Mouse anti-AnkG (1:500, Santa Cruz), Chicken anti-GFP (1:1000 ...
• Acetyltransferases GCN5 and PCAF are required for B lymphocyte maturation in mice

  Valentyn Oksenych, Dan Su, Jeremy A. Daniel, bioRxiv - Immunology 2021

  Quote: ... clone A-11 (1:500, Santa Cruz Biotechnol-ogy ...
• Combining Plasma Extracellular Vesicle Let-7b-5p, miR-184 and Circulating miR-22-3p Levels for NSCLC Diagnosis and for Predicting Drug Resistance

  G. P. Vadla, et al., bioRxiv - Cancer Biology 2021

  Quote: ... and flotillin (1:1000, Santa Cruz #74566). Secondary antibodies were anti-mouse horseradish peroxidase (1:10000 ...
• Hepatocyte Cell Cycle Progression Depends on a Transcriptional Repressor Cascade Downstream of Wnt Signaling

  Yinhua Jin, et al., bioRxiv - Cell Biology 2021

  Quote: ... Hnf4a (rabbit 1:50; Santa Cruz sc8987). Samples were imaged at 20X magnification using a Zeiss Imager Z.2 and processed and analyzed with the ImageJ software.
• Lin28a rejuvenates muscle stem cells via mitochondrial optimization

  Peng Wang, et al., bioRxiv - Cell Biology 2021

  Quote: ... P53 (sc-126; Santa Cruz; 1:100), IMP1/2/3 (sc-271785 ...
• Lin28a rejuvenates muscle stem cells via mitochondrial optimization

  Peng Wang, et al., bioRxiv - Cell Biology 2021

  Quote: ... α-actinin (sc-7453; Santa Cruz; 1:500), 8-oxo-guanine (ab206461 ...
• Phylogenetic profiling and cellular analyses of ARL16 reveal roles in traffic of IFT140 and INPP5E

  Skylar I. Dewees, et al., bioRxiv - Cell Biology 2021

  Quote: ... CEP164 (1:100; Santa Cruz; sc-515403), rootletin (1:1000 ...
• The ARF GAPs ELMOD1 and ELMOD3 act at the Golgi and Cilia to Regulate Ciliogenesis and Ciliary Protein Traffic

  Rachel E. Turn, et al., bioRxiv - Cell Biology 2021

  Quote: ... CEP164 (1:100; Santa Cruz; sc-515403), CP110 (1:100 ...
• KDM6A mediated expression of the long noncoding RNA DINO causes TP53 tumor suppressor stabilization in Human Papillomavirus type 16 E7 expressing cells

  Surendra Sharma, Karl Munger, bioRxiv - Cancer Biology 2020

  Quote: ... E2F1 (sc-251, Santa Cruz, 1:500), KDM6A (ab36938 ...
• Membrane metalloendopeptidase suppresses prostate carcinogenesis by attenuating effects of gastrin-releasing peptide on stem/progenitor cells

  Chieh-Yang Cheng, et al., bioRxiv - Cancer Biology 2019

  Quote: ... NT (Santa Cruz, #sc-20806, 1:1000), and VIP (Abcam ...
• Membrane metalloendopeptidase suppresses prostate carcinogenesis by attenuating effects of gastrin-releasing peptide on stem/progenitor cells

  Chieh-Yang Cheng, et al., bioRxiv - Cancer Biology 2019

  Quote: ... GRP (Santa Cruz, #sc-7788, 1:100), NT (Santa Cruz ...
• Membrane metalloendopeptidase suppresses prostate carcinogenesis by attenuating effects of gastrin-releasing peptide on stem/progenitor cells

  Chieh-Yang Cheng, et al., bioRxiv - Cancer Biology 2019

  Quote: ... p63 (Santa Cruz, #sc-8431, 1:1000), PTEN (Cell Signaling Technology ...
• Sporadic activation of an oxidative stress-dependent NRF2–p53 signaling network in breast epithelial spheroids and premalignancies

  Elizabeth J. Pereira, et al., bioRxiv - Cancer Biology 2019

  Quote: ... p53 (Santa Cruz #sc-126, 1:200). Slides were incubated the next day for 1 hr in the following secondary antibodies ...
• The IRE1/XBP1 signaling axis promotes skeletal muscle regeneration through a cell non-autonomous mechanism

  Anirban Roy, et al., bioRxiv - Cell Biology 2021

  Quote: ... or anti-MyoD (1:200, Santa Cruz Biotechnology Cat# sc-377460 RRID:AB_631992 ...
• Mitochondrial Proteome of Affected Neurons in a Mouse Model of Leigh Syndrome

  Alejandro Gella, et al., bioRxiv - Neuroscience 2019

  Quote: ... TOM20 (1:5,000, #sc11415 Santa Cruz Biotech), β-actin (1:40,000 ...
• Bromelain Inhibits SARS-CoV-2 Infection in VeroE6 Cells

  Satish Sagar, et al., bioRxiv - Microbiology 2020

  Quote: ... 1:1000 (Santa Cruz Biotechnology, TX, USA); anti-SARS Spike protein 0.05 μg/ml ...
• Nuclear dengue virus NS5 antagonizes expression of PAF1-dependent immune response genes

  Marine J. Petit, et al., bioRxiv - Microbiology 2021

  Quote: ... or STAT2 (1:200, Santa Cruz Biotechnology) (S1 Fig) ...