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201 - 250 of 8014 citations for 1 6 Chloropyridazin 3 yl piperidine 4 carboxamide since 2020

• Analysis of alternative mRNA splicing in vemurafenib-resistant melanoma cells

  Honey Bokharaie, Walter Kolch, Aleksandar Krstic, bioRxiv - Cancer Biology 2022

  Quote: ... ppERK1/2 (E-4) (1/10,000 dilution, #sc-7383, Santa Cruz, Mouse), tERK1/2 (1/10,000 dilution ...
• Mechanisms of insertions at a DNA double-strand break

  Jaewon Min, et al., bioRxiv - Molecular Biology 2022

  Quote: ... anti-β-Actin (1:1000; C-4, Santa Cruz Biotechnology, sc-47778). anti-rabbit immunoglobulin G (IgG ...
• Prostaglandin E₂ controls the metabolic adaptation of T cells to the intestinal microenvironment

  Matteo Villa, et al., bioRxiv - Immunology 2023

  Quote: ... anti-EP4 (encoded by Ptger4, clone C-4, 1:100, Santa Cruz), anti-ATG5 (clone D5F5U ...
• ODF2 negatively regulates CP110 levels at centrioles/basal bodies to control biogenesis of primary cilia

  Madeline Otto, Sigrid Hoyer-Fender, bioRxiv - Cell Biology 2023

  Quote: ... Samples were incubated with the primary antibodies anti-acetylated α-tubulin (clone 6-11B-1; Santa Cruz Biotechnology ...
• Low STING expression in a transplantable Kras^G12D/P53^ko lung cancer model contributes to SiglecF⁺ neutrophil and CD103⁺Treg accumulation in tumors

  Laurent Gros, et al., bioRxiv - Cancer Biology 2021

  Quote: ... HSC70 (Santa Cruz Biotechnology, (B-6) Ref ...
• Rapid and precise genome engineering in a naturally short-lived vertebrate

  Ravi D. Nath, et al., bioRxiv - Genetics 2022

  Quote: ... extracted whole brain samples from 1–4-month-old animals were fixed overnight in 4% paraformaldehyde in PBS (Santa Cruz Biotechnology, SC281692) at 4°C and then washed for 12 hrs in 1xPBS (Corning ...
• Social memory in female mice is rapidly modulated by 17β-estradiol through ERK and Akt modulation of synapse formation

  Paul A. S. Sheppard, et al., bioRxiv - Neuroscience 2022

  Quote: ... or 10ng/side of PI3K inhibitor 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002; Santa Cruz Biotechnology, Dallas, TX); or vehicle (50% dimethyl sulfoxide [DMSO] in 0.9% NaCl solution ...
• The molecular basis of ubiquitin-specific protease 8 autoinhibition by the WW-like domain

  Keijun Kakihara, et al., bioRxiv - Biochemistry 2021

  Quote: ... and anti-14-3-3 antibody (#SC-1657, Santa Cruz). The secondary antibodies used were peroxidase-conjugated anti-mouse IgG ...
• Spatial, Quantitative and Functional Deconstruction of Virus and Host Protein Interactions Inside Intact Cytomegalovirus Particles

  Boris Bogdanow, et al., bioRxiv - Microbiology 2022

  Quote: ... anti-14-3-3 (clone H8, sc-1657, Santa Cruz). Blots were developed using horseradish peroxidase-conjugated secondary antibodies in conjunction with suitable enhanced chemiluminescence detection systems.
• Disease-modifying effects of sodium selenate in a model of drug-resistant, temporal lobe epilepsy

  Pablo M. Casillas-Espinosa, et al., bioRxiv - Neuroscience 2022

  Quote: ... and Glyceraldehyde 3-phosphate dehydrogenase (GAPDH; 1:200, Santa Cruz Biotechnology #sc-47724, USA) was used as loading control ...
• Nuclear Factor I in neurons, glia and during the formation of Müller glia-derived progenitor cells in avian, porcine and primate retinas

  Heithem M. El-Hodiri, et al., bioRxiv - Neuroscience 2021

  Quote: ... (3) goat anti-Sox2 was used at 1:1000 (Y-17; Santa Cruz Biotechnology). The antibody was raised to the recombinant C-terminus of human Sox2 and recognizes a single 34 kDa band in Western blot analysis of lysate from mouse embryonic stem cells (manufacturer) ...
• Condensate-mediated reactivation of mumps virus infection under stress

  Xiaojie Zhang, et al., bioRxiv - Cell Biology 2021

  Quote: ... and glyceraldehyde-3-phosphate dehydrogenase (GAPDH, 1:4,000; clone 6C5; Santa Cruz, sc-32233) as loading control ...
• In vivo KRAS G12D/V degradation mediated by CANDDY using a modified proteasome inhibitor

  Satoshi Imanishi, et al., bioRxiv - Pharmacology and Toxicology 2022

  Quote: ... and glyceraldehyde 3-phosphate dehydrogenase (GAPDH, 1:10000, sc-32233; Santa Cruz Biotechnology, Inc.) and rabbit polyclonal antibodies specific for HRAS (1:1000 ...
• Antagonism between viral infection and innate immunity at the single-cell level

  Frederic Grabowski, et al., bioRxiv - Systems Biology 2022

  Quote: ... anti-OAS1 (clone F-3) (catalog number sc-374656; Santa Cruz Biotechnology; 1:1000), anti-Respiratory Syncytial Virus (clone 2F7 ...
• Collapse of late endosomal pH elicits a rapid Rab7 response via V-ATPase and RILP

  R.J. Mulligan, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-Galectin-3 (mouse monoclonal; 1:100 IF; Santa Cruz sc-25279; RRID: AB_627656), anti-Galectin-3 (rat monoclonal ...
• Collapse of late endosomal pH elicits a rapid Rab7 response via V-ATPase and RILP

  R.J. Mulligan, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-Galectin-3 (rat monoclonal; 1:100 IF; Santa Cruz sc-23938; RRID: AB_627658), anti-GFP (rabbit polyclonal ...
• Inhibition of the transcription factor PU.1 suppresses tumor growth in mice by promoting the recruitment of cytotoxic lymphocytes through the CXCL9-CXCR3 axis

  Nichita Sleapnicov, et al., bioRxiv - Immunology 2024

  Quote: ... PU.1 antibody (C-3) and anti-β-actin were purchased from Santa Cruz Biotechnology (Dallas ...
• Female specific dysfunction of sensory neocortical circuits in a mouse model of autism mediated by mGluR5 and Estrogen Receptor α

  Gemma Molinaro, et al., bioRxiv - Neuroscience 2024

  Quote: ... Then 10% of the lysate was set aside for use as an input control and the rest was tumbled overnight at 4°C with 7 µl of ERα antibody or 1.4 µg of Homer antibody (Santa Cruz Biotechnology, D-3). The same isotype IgG was used as control for the specificity of the ERα (Abcam #ab172730 ...
• MUC5B mobilizes and MUC5AC spatially aligns mucociliary transport on human airway epithelium

  Daniel Song, et al., bioRxiv - Physiology 2022

  Quote: ... The antibodies that were used were anti-acetylated alpha tubulin AlexaFluor 647 (cilia marker, clone 6-11B-1, sc23950, Santa Cruz, 1:2000) and ZO-1 monocolonal antibody AlexaFluor 488 (tight junction marker ...
• Stem cell quiescence requires PRC2/PRC1-mediated mitochondrial checkpoint

  JR Ishibashi, et al., bioRxiv - Biochemistry 2021

  Quote: ... The antibodies used for immunostaining were anti-Oct-4 (Santa Cruz, 1:100), anti-ATP synthase β subunit (Abcam ...
• Hsp27 reduces glycation-induced toxicity and aggregation of α-synuclein

  Hugo Vicente Miranda, et al., bioRxiv - Neuroscience 2020

  Quote: ... Hsp27 (anti-Hsp27 F-4 1:2000; Santa Cruz Biotechnology, Dallas, TX, USA), anti-MGO-derived Advanced Glycation and Products (AGEs ...
• PRDM3/16 Regulate Chromatin Accessibility Required for NKX2-1 Mediated Alveolar Epithelial Differentiation and Function

  Hua He, et al., bioRxiv - Developmental Biology 2023

  Quote: ... Mouse anti-SOX2 clone E-4 (Santa Cruz Biotechnology SC-365823; 1:100), Rabbit anti-SOX9 (Millipore AB5535 ...
• Annulate Lamellae biogenesis is essential for nuclear pore function

  Junyan Lin, et al., bioRxiv - Cell Biology 2024

  Quote: ... mouse monoclonal anti-Pericentrin 1 (D-4) (Nup85) (Santa Cruz Biotechnology, sc-376111), rabbit monoclonal anti-SEC13 (R&D systems ...
• A sexually dimorphic hepatic cycle of periportal VLDL generation and subsequent pericentral VLDLR-mediated lipoprotein re-uptake

  Tomaz Martini, et al., bioRxiv - Physiology 2024

  Quote: ... mouse anti-GS/GLUL (Santa Cruz sc-74430, clone E-4, 1 : 100) and goat anti-E-CAD (R&D systems AF478 ...
• Early Signaling Events in Renal Compensatory Hypertrophy Revealed by Multi-Omics

  Hiroaki Kikuchi, et al., bioRxiv - Systems Biology 2022

  Quote: ... mouse anti V-ATPase B1/B2 (F-6, sc-55544, Santa Cruz Biotechnology, Santa Cruz, CA, 1:100), anti-chicken AQP2 (CC 265 ...
• Early Signaling Events in Renal Compensatory Hypertrophy Revealed by Multi-Omics

  Hiroaki Kikuchi, et al., bioRxiv - Systems Biology 2022

  Quote: ... mouse anti V-ATPase B1/B2 (F-6, sc-55544, Santa Cruz Biotechnology, Santa Cruz, CA, 1:100), anti-chicken AQP2 (CC 265 ...
• Nucleoplasmic Lamin C Rapidly Accumulates at Sites of Nuclear Envelope Rupture with BAF and cGAS

  Yohei Kono, et al., bioRxiv - Cell Biology 2022

  Quote: Primary antibodies used for indirect immunofluorescence were mouse monoclonal anti-LA (1:500; 4A58; sc-71481, or 1:1,000; C-3; sc-518013, Santa Cruz), rabbit polyclonal anti-LA (1:2,000 ...
• Changes in cellular signaling patterns before and after stroke in the middle cerebral arteries of stroke prone spontaneously hypertensive rats

  Killol Chokshi, et al., bioRxiv - Molecular Biology 2020

  Quote: ... elastin microfibril interfacer 1 [EMILIN-1) and glyceraldehyde 3-phosphate dehydrogenase (GAPDH) Antibody for total PKC was from Santa Cruz Biotechnology (TX ...
• Human striatal progenitor cells that contain inducible safeguards and overexpress BDNF rescue Huntington’s disease phenotypes in R6/2 mice

  Danielle A. Simmons, et al., bioRxiv - Neuroscience 2024

  Quote: ... anti-OCT3/4 (sc-5279, 1:200), anti-SOX2 (sc-365823, 1:200), anti-NANOG (sc-293121, 1:200) (all from Santa Cruz Biotechnology), anti-PAX6 (DSHB ...
• Klebsiella pneumoniae hijacks the Toll-IL-1R protein SARM1 in a type I IFN-dependent manner to antagonize host immunity

  Claudia Feriotti, et al., bioRxiv - Microbiology 2021

  Quote: ... anti-phospho-AKT1/2/3 (Ser 473) (anti-rabbit, 1:1000; sc-33437, Santa Cruz), anti-phospho-IKKα/β (Ser176/180)(16A6 ...
• A human papillomavirus 16 E2-TopBP1 dependent SIRT1-p300 acetylation switch regulates mitotic viral and human protein levels

  Apurva T. Prabhakar, et al., bioRxiv - Molecular Biology 2024

  Quote: ... and anti-Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) 1:10,000 (Santa Cruz; catalog no. sc-47724).
• Interaction between histone residue H3K56 and mismatch repair protein MutSβ drives CAG repeat expansion

  Jinzhen Guo, Wei Yang, Guo-Min Li, bioRxiv - Molecular Biology 2024

  Quote: Nuclear extracts (1 mg) were incubated with 3 μg of α-IgG (Santa Cruz Biotechnology), α-H3 antibody (Abcam ...
• CK2 alpha prime and alpha-synuclein pathogenic functional interaction mediates synaptic dysregulation in Huntington’s disease

  Dahyun Yu, et al., bioRxiv - Neuroscience 2022

  Quote: ... IL-6 (Santa Cruz Bio sc-32296). For cell number (Ctip ...
• Zika virus hijacks extracellular vesicle tetraspanin pathways for cell-to-cell transmission

  Sara B. York, et al., bioRxiv - Microbiology 2021

  Quote: ... HSC70 ([B-6] Santa Cruz; SC-7298), CD63 ([TS63] Abcam ...
• Interleukin-6 mediates PSAT1 expression and serine metabolism in TSC2-deficient cells

  Ji Wang, et al., bioRxiv - Pathology 2021

  Quote: ... IL-6 (Santa Cruz Biotechnology, sc-57315), STAT3 (9139S) ...
• Chaperone-mediated Autophagy Deficiency Reprograms Cancer Metabolism Via TGFβ Signaling to drive Mesenchymal Tumor Growth

  Xun Zhou, et al., bioRxiv - Cancer Biology 2022

  Quote: ... TGFβR2 (Abcam, ab184948; Santa Cruz, E-6), TGFβR1 (Abcam ...
• Centriolar satellites are sites of translation of centrosomal and ciliary proteins

  Claudia Pachinger, et al., bioRxiv - Cell Biology 2024

  Quote: ... mouse anti-hsPCM1 (G-6, Santa Cruz), rabbit anti-PCM1 (6) ...
• Selective Enhancer Dependencies in MYC-Intact and MYC-Rearranged Germinal Center B-cell Diffuse Large B-cell Lymphoma

  Ashwin R. Iyer, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Bcl-6 (sc-7388, Santa Cruz Biotechnology), c-Myc (5605S ...
• A lysosomal surveillance response (LySR) that reduces proteotoxicity and extends healthspan

  Terytty Yang Li, et al., bioRxiv - Cell Biology 2022

  Quote: ... ChIP for human endogenous GATA4 in SH-SY5Y cells was carried out using the GATA-4 (G-4) (Cat. sc-25310, Santa Cruz, 1:50, RRID:AB_627667). All primers for qRT-PCR or ChIP-qPCR are as indicated in Table S3.
• Thiol-ene cross-linked alginate hydrogel encapsulation modulates the extracellular matrix of kidney organoids by reducing abnormal type 1a1 collagen deposition

  Thomas Geuens, et al., bioRxiv - Bioengineering 2020

  Quote: ... Triton X-100 in PBS and incubated overnight at 4°C in the dark with the following primary antibodies against: OCT3/4 (sc-5279, Santa Cruz Biotechnology, 1:100), SOX2 (sc-365823 ...
• PSGL-1 inhibits HIV-1 infection by restricting actin dynamics and sequestering HIV envelope proteins

  Ying Liu, et al., bioRxiv - Microbiology 2020

  Quote: ... 4×105 cells were fixed and stained with anti-PSGL-1 antibody (Santa Cruz Biotech, sc-13535, 1:200) and Alexa Fluor 568 Phalloidin (Molecular Probes ...
• Peptidylarginine deiminase IV (PADI4) is not essential for cell-autonomous HSC maintenance and normal haematopoiesis

  Christine Young, et al., bioRxiv - Developmental Biology 2021

  Quote: ... and anti-Actin (Santa Cruz, sc-1616, 1:500, O/N at 4°C). After incubation with appropriate horseradish peroxidase-coupled secondary antibody ...
• Core cysteine residues in the PAN domain are critical for HGF/c-MET signaling

  Debjani Pal, et al., bioRxiv - Cell Biology 2021

  Quote: ... Met Antibody (clone D-4) (#sc-514148; 1:500) was purchased from Santa Cruz Biotechnology ...
• PCMD-1 bridges the centrioles and the PCM scaffold in C. elegans

  Lisa Stenzel, et al., bioRxiv - Cell Biology 2020

  Quote: ... followed by incubation with primary antibodies anti-SAS-4 (1:500, Santa Cruz Biotechnology), anti-SPD-5 (1:1000 ...
• Metabolic enhancement of mammalian developmental pausing

  Vera A. van der Weijden, et al., bioRxiv - Developmental Biology 2022

  Quote: ... 1:50 for the Oct3/4 mouse anti-mouse (Santa Cruz, cat.# sc-5279), 1:100 for the H4K16ac rabbit anti-mouse antibody (Millipore ...
• Endogenous tagging using split mNeonGreen in human iPSCs for live imaging studies

  Mathieu C. Husser, et al., bioRxiv - Cell Biology 2024

  Quote: ... 1:20 anti-OCT3/4 antibody (10 μg/mL final concentration; Santa Cruz Biotechnology), or 1:20 Alexa488-conjugated anti-TRA-1-60 antibody (7.5 μg/mL final concentration ...
• APE1 associates with 60S ribosomes and tRNAs and regulates the expression of IGF2BP1

  Wai Ming Li, Belal Tafech, Chow H. Lee, bioRxiv - Biochemistry 2023

  Quote: ... The following antibodies were used: anti-APE1 (C-4, 1:500, Santa Cruz Biotechnology); anti-fibrillarin (C13C3 ...
• APE1 associates with 60S ribosomes and tRNAs and regulates the expression of IGF2BP1

  Wai Ming Li, Belal Tafech, Chow H. Lee, bioRxiv - Biochemistry 2023

  Quote: ... the cells were immunostained for APE1 (anti-APE1 C-4, 1:200, Santa Cruz) and another marker using antibodies against calnexin (1:50) ...
• BNIP3 phosphorylation by JNK1/2 promotes mitophagy via enhancing its stability under hypoxia

  Yun-Ling He, et al., bioRxiv - Cell Biology 2020

  Quote: ... PM020), anti-HA (1:1,000, mouse mAb, MBL, M180-3) and anti-TOMM20 (1:1,000, rabbit pAb, Santa Cruz, sc-11415). The fluorescent secondary antibodies were conjugated with either Alexa Fluor 594 (1:1,000 ...
• The ASC inflammasome adapter controls the extent of peripheral protein aggregate deposition in inflammation-associated amyloidosis

  Marco Losa, et al., bioRxiv - Molecular Biology 2023

  Quote: ... The following assay positive controls were used at a starting concentration of 1 µg/ml: (1) Anti-ASC/TMS1/PYCARD Antibody (B-3) mouse monoclonal IgG1 (sc-514414, Santa Cruz); (2 ...