Labshake search

101 - 150 of 8014 citations for 1 6 Chloropyridazin 3 yl piperidine 4 carboxamide since 2020

• Osteosarcoma tumors maintain intra-tumoral transcriptional heterogeneity during bone and lung colonization

  Sanjana Rajan, et al., bioRxiv - Cancer Biology 2022

  Quote: ... monocarboxylate transporter 4 (Santa Cruz Biotechnology, [D-1] sc-376140, 1:50) and vimentin (Cell Signaling Technology ...
• SUMOylation- and GAR1-dependent regulation of dyskerin nuclear and subnuclear localization

  D.E. MacNeil, et al., bioRxiv - Cell Biology 2020

  Quote: ... or mouse anti-dyskerin (Santa Cruz H-3, 1:25) in PBG (1% cold fish water gelatin ...
• Lin28a rejuvenates muscle stem cells via mitochondrial optimization

  Peng Wang, et al., bioRxiv - Cell Biology 2021

  Quote: ... citrate synthase (G-3) (sc-390693; Santa Cruz ; 1:1000).
• The adenoviral E1B-55k protein present in HEK293 cells mediates abnormal accumulation of key WNT signaling proteins in large cytoplasmic aggregates

  Petter Angell Olsen, Stefan Krauss, bioRxiv - Cell Biology 2021

  Quote: ... APC (F-3) (Santa Cruz Biotechnology; sc-9998; 1:50), DVL2 (10B5 ...
• Klebsiella pneumoniae reduces SUMOylation to limit host defence responses

  Joana Sá-Pessoa, et al., bioRxiv - Microbiology 2020

  Quote: ... anti-SUMO2/3 (1:1000, Santa Cruz Biotechnology sc-32873), anti-Ubc9 (1:1000 ...
• Ehrlichia SLiM ligand mimetic activates Hedgehog signaling to engage a BCL-2 anti-apoptotic cellular program

  Caitlan D. Byerly, et al., bioRxiv - Microbiology 2022

  Quote: ... α -GLI-1/2/3 (Santa Cruz Biotechnology, Dallas, TX), α-SHH (Cell Signaling ...
• The transcription regulator Lmo3 is required for cell fate specification in the external globus pallidus

  Shiona Biswas, et al., bioRxiv - Neuroscience 2022

  Quote: ... and rabbit anti-phosphoHistone 3 (1:250; Santa Cruz Biotechnology). Alexa Fluor conjugated secondary antibodies (Molecular probes ...
• Thiol-ene cross-linked alginate hydrogel encapsulation modulates the extracellular matrix of kidney organoids by reducing abnormal type 1a1 collagen deposition

  Thomas Geuens, et al., bioRxiv - Bioengineering 2020

  Quote: ... MEIS1/2/3 (sc-101850, Santa Cruz Biotechnology, 1:300), E-cadherin (ECAD ...
• Organic Dust Exposure Induces Stress Response and Mitochondrial Dysfunction in Monocytic Cells

  Sanjana Mahadev-Bhat, et al., bioRxiv - Cell Biology 2020

  Quote: ... Caspase 1 and Caspase 3 was purchased from Santa Cruz Biotechnology ...
• SUMOylation- and GAR1-dependent regulation of dyskerin nuclear and subnuclear localization

  D.E. MacNeil, et al., bioRxiv - Cell Biology 2020

  Quote: ... anti-His (Santa Cruz, sc-8036, H-3, 1:500), and anti-alpha tubulin (Sigma ...
• SUMOylation- and GAR1-dependent regulation of dyskerin nuclear and subnuclear localization

  D.E. MacNeil, et al., bioRxiv - Cell Biology 2020

  Quote: ... anti-dyskerin (Santa Cruz, sc-373956, H-3, 1:1500), anti-GAR1 (Proteintech ...
• MRCK controls myosin II activation in the polarized cortex of mouse oocytes and promotes spindle rotation and male pronucleus centration

  Anne Bourdais, Benoit Dehapiot, Guillaume Halet, bioRxiv - Cell Biology 2022

  Quote: ... MRCKα (B-3) (1:100; Santa Cruz Biotechnology sc-374568), MRCKβ (A-2 ...
• Early mitochondrial dysfunction proceeds neuroinflammation, synaptic alteration, and autophagy impairment in hippocampus of App knock-in Alzheimer mouse models

  Luana Naia, et al., bioRxiv - Neuroscience 2023

  Quote: ... β3 tubulin (1:2,000) (Santa cruz, Cat. no. sc-80016). After washing with TBS-T for three times ...
• A chemical probe to modulate human GID4 Pro/N-degron interactions

  Dominic D.G Owens, et al., bioRxiv - Molecular Biology 2023

  Quote: ... SAP62 (1:1000; A-3, sc-390444, Santa Cruz Biotechnology), Muskelin (C-12 ...
• Targeting the deNEDDylating enzyme NEDP1 to ameliorate ALS phenotypes through Stress Granules dissolution

  Toufic Kassouf, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse anti-TIA-1 (G-3) (#sc-166247, Santa cruz), mouse anti-eIF4G (A-10 ...
• TRiPPing the sensors: The osmosensing pathway of Polycystin 2

  K.M. Márquez-Nogueras, et al., bioRxiv - Physiology 2023

  Quote: ... PC2 (D-3, 1:500, sc-28331; Santa Cruz Biotechnology), MAP4 (1:1000 ...
• An Aurora kinase A-BOD1L1-PP2A B56 Axis promotes chromosome segregation fidelity

  Thomas J. Kucharski, et al., bioRxiv - Cell Biology 2024

  Quote: ... mouse anti-PP2A B56 Beta (Santa Cruz E-6; IB at 1:500), mouse anti-PP2A B56 Gamma (Santa Cruz A-11 ...
• Loss of TMEM106B exacerbates Tau pathology and neurodegeneration in PS19 mice

  Tuancheng Feng, Huan Du, Fenghua Hu, bioRxiv - Neuroscience 2023

  Quote: ... mouse anti-acetylated alpha Tubulin Antibody (6-11B-1) (Santa Cruz, sc-23950), mouse anti-acetylated Tubulin (Lys40 ...
• A kinetochore-centrosome feedback loop linking CENP-E and Aurora kinases controls chromosome biorientation and congression

  Kruno Vukušić, Iva M. Tolić, bioRxiv - Cell Biology 2024

  Quote: ... mouse monoclonal anti-KIFC1 (M-6, sc-100947, Santa Cruz, diluted 1:500), rabbit polyclonal anti-Kif18a (A301-080A ...
• Master corepressor inactivation through multivalent SLiM-induced polymerization mediated by the oncogene suppressor RAI2

  Nishit Goradia, et al., bioRxiv - Molecular Biology 2024

  Quote: ... HSC70 protein (clone B-6; Santa Cruz Biotechnology, CA, USA, dilution 1:106) was used as a loading control and HRP-(Cell Signaling Technology ...
• Mass spectrometry imaging reveals early metabolic priming of cell lineage in differentiating human induced pluripotent stem cells

  Arina A. Nikitina, et al., bioRxiv - Bioengineering 2022

  Quote: ... Mouse Anti-human Oct-3/4 (C-10) primary antibody (catalog #sc-5279) was purchased from Santa Cruz Biotechnology (Dallas ...
• Adducin Regulates Sarcomere Disassembly During Cardiomyocyte Mitosis

  Feng Xiao, et al., bioRxiv - Cell Biology 2020

  Quote: ... anti-Filamin 1 (E-3, sc-17749, Santa Cruz, 1:100, for Figure 1F), anti-α-adducin (phospho T445 ...
• Tripartite Inhibition of SRC-WNT-PKC Signalling Consolidates Human Naïve Pluripotency

  Jonathan Bayerl, et al., bioRxiv - Developmental Biology 2020

  Quote: ... rabbit anti-OCT3/4 (Santa Cruz SC9081, 1:400), mouse anti-OCT3/4 (Santa Cruz SC5279 ...
• Tripartite Inhibition of SRC-WNT-PKC Signalling Consolidates Human Naïve Pluripotency

  Jonathan Bayerl, et al., bioRxiv - Developmental Biology 2020

  Quote: ... mouse anti-OCT3/4 (Santa Cruz SC5279, 1:100), rabbit anti-KLF4 (Santa Cruz SC20691) ...
• ECSIT prevents Alzheimer’s disease pathology by regulating neuronal mitochondrial ROS and mitophagy

  Alice Lepelley, et al., bioRxiv - Neuroscience 2020

  Quote: ... Actin (1:1,000, Santa Cruz Biotechnology, clone C-4), GFP (1:1,000 ...
• ZFP207 controls pluripotency by multiple post-transcriptional mechanisms

  Sandhya Malla, et al., bioRxiv - Cell Biology 2021

  Quote: ... Anti-OCT3/4 (Santa Cruz Biotechnology, sc8628, 1:2500), Nucleolin (Abcam ...
• ZFP207 controls pluripotency by multiple post-transcriptional mechanisms

  Sandhya Malla, et al., bioRxiv - Cell Biology 2021

  Quote: ... Anti-OCT3/4 (Santa Cruz Biotechnology, sc8628, 1:2500), Goat Anti-Rabbit IgG H&L (HRP ...
• Systematic analysis of ADP-ribose detection reagents and optimisation of sample preparation to detect ADP-ribosylation in vitro and in cells

  Lisa Weixler, et al., bioRxiv - Molecular Biology 2022

  Quote: ... and benzonase 1:10.000 (9025-65-4, Santa Cruz). Lysates were centrifuged at 4°C and maximum speed for 15 minutes to remove insoluble material ...
• Imperfect innate immune antagonism renders SARS-CoV-2 vulnerable towards IFN-γ and -λ

  Manuel Hayn, et al., bioRxiv - Microbiology 2020

  Quote: ... LC3a/β (1:200, G-4, Santa Cruz Biotechnology), Beclin-1 (1:1,000 ...
• CelltypeR: A flow cytometry pipeline to annotate, characterize and isolate single cells from brain organoids

  Rhalena A. Thomas, et al., bioRxiv - Neuroscience 2023

  Quote: ... SSEA-4 (1:200, Santa Cruz Biotechnology sc-21704); in blocking buffer overnight at 4 °C ...
• Early nuclear phenotypes and reactive transformation in human iPSC-derived astrocytes from ALS patients with SOD1 mutations

  Vincent Soubannier, et al., bioRxiv - Neuroscience 2023

  Quote: ... or goat anti-OCT3/4 (1/500; Santa Cruz Biotechnology ...
• The ciliary gene INPP5E confers dorsal telencephalic identity to human cortical organoids by negatively regulating Sonic Hedgehog signalling

  Leah Schembs, et al., bioRxiv - Developmental Biology 2021

  Quote: ... followed by an overnight incubation at 4°C with Rabbit-anti-NANOG (1/800, Cell Signalling, #3580S) and Mouse-anti-OCT3/4 (1/250, Santa Cruz, sc-5279) antibodies diluted in BB supplemented with 0.1% Triton-X ...
• Binding of CEP152 to PLK4 stimulates kinase activity to promote centriole assembly

  Hazal Kübra Gürkaşlar, Ingrid Hoffmann, bioRxiv - Cell Biology 2024

  Quote: ... mouse anti-ninein (1:1000 IF; F5), mouse anti-SAS-6 (1:500 IF, 1:100 U-ExM) from Santa Cruz Biotechnology ...
• Dynein acts to cluster glutamate receptors and traffic the PIP5 kinase, Skittles, to regulate postsynaptic membrane organization at the neuromuscular junction

  Amanda L. Neisch, et al., bioRxiv - Cell Biology 2021

  Quote: ... mouse anti acetylated α-tubulin 6-11B-1 Alexa488 conjugated 1:50 (Santa Cruz Biotechnology, Inc., Dallas, TX), mouse anti-Dhc64c P1H4 at 1:400 (McGrail and Hays ...
• Genome-wide Screens Identify Lineage- and Tumor Specific-Genes Modulating MHC-I and MHC-II Immunosurveillance in Human Lymphomas

  Devin Dersh, et al., bioRxiv - Cancer Biology 2020

  Quote: ... anti-14-3-3 (Santa Cruz).
• SOD2 in Skeletal Muscle: New Insights from an Inducible Deletion Model

  Aowen Zhuang, et al., bioRxiv - Physiology 2021

  Quote: ... pan 14-3-3 (Santa Cruz), phospho-T172 AMPKalpha (Cell Signaling) ...
• An Enhancer Trap system to track developmental dynamics in Marchantia polymorpha

  Alan O. Marron, et al., bioRxiv - Plant Biology 2023

  Quote: ... Auxin synthesis inhibitor treatments were done by growing gemmae on plates made with 10µM 5-(4-chlorophenyl)-4H-1,2,4-triazole-3-thiol (yucasin) (ChemCruz, Santa Cruz Biotechnology) or 100µM L-kynurenine (Sigma ...
• ATP13A4 upregulation drives the elevated polyamine transport system in the breast cancer cell line MCF7

  Sarah van Veen, et al., bioRxiv - Cell Biology 2023

  Quote: ... N-(3-aminopropyl)cyclohexylamine (APCHA; sc-202715) and trans-4-methylcyclohexylamine (4MCHA; sc-272662) were obtained from Santa Cruz Biotechnology ...
• Impact of repeated cryopreservation on embryo health and implantation potential

  Tong Li, et al., bioRxiv - Developmental Biology 2023

  Quote: ... The embryos were then incubated with anti-OCT-3/4 mouse primary antibody (Santa Cruz Biotech, Dallas, TX, USA) at 1:100 dilution ...
• Seoul orthohantavirus evades innate immune activation by reservoir endothelial cells

  Stefan Klimaj, et al., bioRxiv - Microbiology 2024

  Quote: ... or Mx 1/2/3 1:400 in PBS (Santa Cruz Biotechnology, sc-166412 AF488). Representative images were acquired via the EVOS FL Auto imaging system (Thermo Fisher Scientific).
• Endothelial Lipase Variant, T111I, Does Not Alter Inhibition by Angiopoietin-like Proteins

  Kelli L. Sylvers-Davie, et al., bioRxiv - Biochemistry 2023

  Quote: ... 80% confluent RHMVECs in 6-well plates were transduced with human T111I EL (pKS18) lentiviruses with 4 μg/ml Polybrene (#134220; Santa Cruz Biotechnology) in a total volume of 1 ml DMEM ...
• Phase-specific signatures of wound fibroblasts and matrix patterns define cancer-associated fibroblast subtypes

  Mateusz S. Wietecha, et al., bioRxiv - Genomics 2022

  Quote: ... or 3) goat anti-fibronectin (1:200; Santa Cruz; #sc-6953) and rabbit anti-MFAP4 (1:100 ...
• Distinctive chaperonopathy in skeletal muscle associated with the dominant variant in DNAJB4

  Michio Inoue, et al., bioRxiv - Neuroscience 2022

  Quote: ... sections were probed with caveolin-3 (Santa Cruz Biotechnology, 1:100) followed by appropriate secondary antibodies ...
• Loss of CLN3 in microglia leads to impaired lipid metabolism and myelin turnover

  Seda Yasa, et al., bioRxiv - Neuroscience 2024

  Quote: ... anti-Galectin 3 (WB: 1:500, Santa Cruz Biotech sc-32790), anti-PDI (IF ...
• NRF2 connects Src tyrosine kinase to ferroptosis resistance in glioblastoma

  Claudia Cirotti, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-Heme Oxygenase 1 (A-3) (sc-136960, Santa Cruz Biotechnology), anti-NQO1 (A-180 ...
• Loss of SPNS1, a lysosomal transporter, in the nervous system causes dysmyelination and white matter dysplasia

  Yoshinobu Ichimura, et al., bioRxiv - Cell Biology 2024

  Quote: ... and GALECTIN-3 (sc-23938, Santa Cruz Biotechnology Inc.; 1:200) were used as primary antibodies ...
• A catalytic-independent function of human DNA polymerase Kappa controls the pool of the Checkpoint Kinase 1

  Marina Dall’Osto, et al., bioRxiv - Cell Biology 2021

  Quote: ... ORC2 (MBL M055-3 - 1/1000), ORC4 (Transduction laboratories H83120, 1/500) MCM7 (Santa Cruz sc22782 - 1/1000), MCM2 (Abcam ab4461 - 1/2000) ...
• Spatial modeling reveals nuclear phosphorylation and subcellular shuttling of YAP upon drug-induced liver injury

  Lilija Wehling, et al., bioRxiv - Molecular Biology 2022

  Quote: ... overnight at 4°C: anti-YAP (1:25, Santa Cruz Biotechnology ...
• A conserved ubiquitin- and ESCRT-dependent pathway to regulate human lysosomal membrane proteins

  Weichao Zhang, et al., bioRxiv - Cell Biology 2020

  Quote: ... mouse-anti-EEA (1:500, G-4, Santa Cruz Biotechnology), rabbit-GAPDH (1:2000 ...
• Meiosis-Specific Cohesin Complexes Display Distinct and Essential Roles in Mitotic ESC Chromosomes

  Eui-Hwan Choi, et al., bioRxiv - Molecular Biology 2021

  Quote: ... anti-mouse OCT3/4 (Santa Cruz; sc-5297; 1:3,000), anti-rat RPA (Cell signaling ...