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1801 - 1850 of 8862 citations for 6 1 4 dioxa 8 azaspiro 4.5 decan 8 yl 3 hydroxy 2 iminopyrimidin 4 amine since 2019

• Triplet kinase-phosphatase targeting to overcome kinase inhibitor tolerance in brain tumor cells

  Oxana V. Denisova, et al., bioRxiv - Cancer Biology 2022

  Quote: ... PME-1 (Santa Cruz, sc-20086, 1:1,000), β-actin (Sigma-Aldrich ...
• Orchestration of alternative splicing regulates bone marrow mesenchymal stem cells fate during aging

  Ye Xiao, et al., bioRxiv - Cell Biology 2022

  Quote: ... Thrombospondin 1 (Santa Cruz, sc-393504, 1:500), Colla2 (Santa Cruz ...
• Fgf9-Nolz-1-Wnt2 Signaling Axis Regulates Morphogenesis of the Lung

  Shih-Yun Chen, Fu-Chin Liu, bioRxiv - Developmental Biology 2022

  Quote: ... rat anti-PECAM-1 (1:500, Santa Cruz) and mouse anti-myc (1:1000 ...
• Mitotic H3K9ac is controlled by phase-specific activity of HDAC2, HDAC3 and SIRT1

  Shashi Gandhi, et al., bioRxiv - Cell Biology 2022

  Quote: ... HAT-1(Santa cruz # sc-390562; 1:1000), SIRT1(Cell Signalling #8469 ...
• Mitotic H3K9ac is controlled by phase-specific activity of HDAC2, HDAC3 and SIRT1

  Shashi Gandhi, et al., bioRxiv - Cell Biology 2022

  Quote: ... HAT-1 (Santa cruz # sc-390562; 1:100), SIRT1 (Cell Signalling #8469 ...
• Defining melanoma combination therapies that provide senolytic sensitivity in human melanoma cells

  Daméhan Tchelougou, et al., bioRxiv - Cancer Biology 2023

  Quote: ... p53 (clone DO-1, Santa Cruz 1/5000) ERK-1/2 and phospho-ERK-1/2 ...
• Spatial control of the APC/C ensures the rapid degradation of Cyclin B1

  Luca Cirillo, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-p53 (1:1000, DO-1 – Santa Cruz), anti-p21 (1:1000 ...
• Physiological role and mechanisms of action for a long noncoding haplotype region

  Hong Xue, et al., bioRxiv - Genetics 2024

  Quote: ... TRA-1 (1:100, sc-21706, Santa Cruz) and SSEA4 (1:100 ...
• Protein CoAlation on TXNRD2 regulates mitochondrial thioredoxin system to protect against ferroptosis

  Chao-Chieh Lin, et al., bioRxiv - Cell Biology 2024

  Quote: ... TXNRD1 (1:1000, 11117-1-AP, Santa Cruz); TXNRD2 (1:1000 ...
• Under pressure: integrated endothelial cell response to hydrostatic and shear stresses

  Christian J. Mandrycky, et al., bioRxiv - Bioengineering 2024

  Quote: ... AQP-1 (1:100, Santa Cruz sc-25287), GJA4 (1:100 ...
• Simulation of the Gαq /Phospholipase Cβ1 Signaling Pathway Returns Differentiated PC12 Cells to a Stem-like State

  Osama Garwain, et al., bioRxiv - Biochemistry 2020

  Quote: ... Membranes were treated with antibodies diluted 1:1000 in 0.5% BSA and washed 3 times for 5 min before applying secondary antibiotic (anti-mouse or anti-goat from Santa Cruz Biotechnology and Anti-Rabbit from Abcam at a concentration of 1:1000 ...
• Ouabain enhances cell-cell adhesion mediated by β1-subunits of the Na+,K+-ATPase in CHO fibroblasts.

  Claudia Andrea Vilchis-Nestor, et al., bioRxiv - Cell Biology 2019

  Quote: Monolayers of CHO cells grown on multi-well plates were washed 3 times with ice-cold PBS and incubated in RIPA buffer (24948A, Santa Cruz) with protease inhibitors (2498 ...
• Targeting metabolic adaptations in the breast cancer–liver metastatic niche using dietary approaches to improve endocrine therapy efficacy

  Qianying Zuo, et al., bioRxiv - Cancer Biology 2022

  Quote: ... ERα–DNA or IgG–DNA complexes were immunoprecipitated using ERα-specific F10 and HC20 antibodies (Santa Cruz Biotech, 3:100 dilution). ChIP DNA was obtained from three pooled biological replicates ...
• Identification of epigenetic modulators as determinants of nuclear size and shape

  Andria Schibler, et al., bioRxiv - Cell Biology 2022

  Quote: ... The array was further washed 3 times in TBST with 10 min for each wash and incubated with HRP conjugated secondary antibody (Santa Cruz) for 1 hour at room temperature ...
• Beta HPV8 E6 Induces Micronuclei Formation and Promotes Chromothripsis

  Dalton Dacus, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Membranes were then probed with the following primary antibodies: glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (Santa Cruz Biotechnologies; catalog no. sc-47724), pATR (Thr1989 ...
• The scaffold protein IQGAP1 links heat-induced stress signals to alternative splicing regulation in gastric cancer cells

  Andrada Birladeanu, et al., bioRxiv - Molecular Biology 2021

  Quote: ... anti-IQGAP1 (clone H109 Santa Cruz Biotechnology, Cat# sc-10792; RRID:AB_2249072; clone D-3, Santa Cruz, Cat# sc-374307; clone C-9, Santa Cruz, Cat# sc-379021 ...
• Defined factors to reactivate cell cycle activity in adult mouse cardiomyocytes

  Justin Judd, Jonathan Lovas, Guo N. Huang, bioRxiv - Developmental Biology 2019

  Quote: ... Staining was performed on formaldehyde fixed samples after permeabilization with 0.1% Triton X-100 and blocking with 3% bovine serum albumin (Santa Cruz Biotechnology) in phosphate-buffered saline ...
• CD44 regulates blood-brain barrier integrity in response to fluid shear stress

  Brandon J. DeOre, et al., bioRxiv - Cell Biology 2020

  Quote: ... Gels were blocked in 5% normal donkey serum or 3% BSA for 30 minutes at room temperature followed by incubating overnight with primary antibodies for either HCAM (CD44)(Santa Cruz), glial fibrillary acidic protein (GFAP) ...
• The NIN-LIKE PROTEIN 7 (NLP7) transcription factor modulates auxin pathways to regulate root cap development

  Narender Kumar, et al., bioRxiv - Plant Biology 2022

  Quote: ... Samples were incubated for one hour in dark at room temperature and subsequently washed again with 3% (w/v) bovine serum albumin or BSA (Santa Cruz) in 1X PBS solution ...
• Npas4-mediated dopaminergic regulation of fear memory states

  BumJin Ko, et al., bioRxiv - Neuroscience 2022

  Quote: ... They were again washed 3 times in DPBS (10 minutes at RT) and then mounted with UltraCruz mounting medium (Santa Cruz) for imaging.
• Vernalization-triggered expression of the antisense transcript COOLAIR is mediated by CBF genes

  Myeongjune Jeon, et al., bioRxiv - Plant Biology 2022

  Quote: ... Anti-myc (MBL, Woburn, MA, USA, #M192-3) and normal mouse IgG1 (Santa Cruz Biotechnology, Santa Cruz, CA, USA, #sc-3877) were used to detect CBF3 protein enrichment at the FLC locus ...
• CAMKV Kinase Signaling Is a Novel Therapeutic Avenue with Prognostic Relevance in Neuroblastoma

  Yang Yu, et al., bioRxiv - Cancer Biology 2024

  Quote: ... CCNA2 (#sc-271682), His-tag (H-3, (#sc-8036), CAMK4 (H-5, c55501) and GATA2 (#sc-267) were from Santa Cruz Biotechnology ...
• Addressing Heterogeneity in direct analysis of Extracellular Vesicles and analogues using Membrane-Sensing Peptides as Pan-Affinity Probes

  Alessandro Gori, et al., bioRxiv - Biochemistry 2023

  Quote: ... The detector antibody (biotinylated CD9, CD63, CD81 antibodies or or CD42a and CD62P by MiltenyBiotech or anti-band 3 from Santa Cruz) is used at the concentration of 0.6 µg/ml ...
• Lysosomal acid lipase-activity as a novel target to efficiently address triple-negative breast cancer high malignancy

  H. Steigerwald, et al., bioRxiv - Cancer Biology 2023

  Quote: ... β-actin and glyceraldehyde 3-phosphate dehydrogenase (GAPDH) expression were determined using mouse antibodies sc-47724 and sc-47778 (Santa Cruz) (1:2500 ...
• Role of vaccinia virus growth factor in stimulating the mTORC1-CAD axis of the de novo pyrimidine pathway under different nutritional cues

  Lara Dsouza, Anil Pant, Blake Pope, Zhilong Yang, bioRxiv - Microbiology 2024

  Quote: ... CAD threonine 456 /pCPS2 (Cat #sc377559) and the anti-glyceraldehyde-3-phosphate dehydrogenase (anti-GAPDH) (Cat #sc-365062) antibody was sourced from Santa Cruz Biotechnology.
• Inhibitory effect of the TSG-6 on the BMP-4/Smad signaling pathway and odonto/osteogenic differentiation of dental pulp stem cells

  Ying Wang, et al., bioRxiv - Cell Biology 2020

  Quote: ... The cells were incubated with primary antibodies (anti-Vimentin, 1:200 dilution, Abcam; anti-cytokeratin 14, 1:200 dilution, Millipore, USA; anti-STRO-1, 1:100 dilution, Santa Cruz) at 4°C overnight and washed with PBS four times ...
• G protein subunit Gγ13-mediated signaling pathway is critical to the inflammation resolution and functional recovery of severely injured lungs

  Yi-Hong Li, et al., bioRxiv - Immunology 2024

  Quote: ... The membranes then were incubated at 4◦C overnight with the primary antibodies diluted in the blocking buffer (rabbit anti-NLRP3 1:1000, Abcam, ab263899; rabbit anti-Gsdmd 1:1000, Abcam, ab219800; mouse anti-caspase-1 1:1000, Santa Cruz Biotechnology ...
• Pathogenic variants of sphingomyelin synthase SMS2 disrupt lipid landscapes in the secretory pathway

  Tolulope Sokoya, et al., bioRxiv - Cell Biology 2022

  Quote: ... mouse monoclonal anti-LAMP-1 (Santa Cruz, sc-20011; IB 1:1,000; IF 1:400), HRP-conjugated goat anti-rabbit IgG (Thermo Fisher Scientific ...
• The LUBAC participates in Lysophosphatidic Acid-induced NF-κB Activation

  Tiphaine Douanne, et al., bioRxiv - Immunology 2020

  Quote: ... Antibodies against HOIL1 (H-1, 1:1,000), GAPDH (6C5, 1:20,000) were from Santa Cruz. Antibodies to phosphorylated IκBα (5A5 ...
• In vivo KRAS G12D/V degradation mediated by CANDDY using a modified proteasome inhibitor

  Satoshi Imanishi, et al., bioRxiv - Pharmacology and Toxicology 2022

  Quote: ... HRAS (1:1000, 18295-1-AP; GAPDH (1:20000, sc-32233; Santa Cruz Biotechnology, Inc.) and rabbit antibodies specific for p-Erk1/2 (phospho-p44/42 MAPK ...
• Neuronal Transcriptome Disruption, Tau Accumulation and Synapse Loss in Alzheimer’s Knock-in Mice Require Cellular Prion Protein

  Austin Stoner, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-LAMP-1 (1D4B) (lysosome-associated membrane protein 1; Santa Cruz sc-19992; 1:500) anti-IBA1 (ionized calcium-binding adapter molecule 1 ...
• Neurovascular unit adjustments following chronic distress explain motivational deficits in mice

  Lidia Cabeza, et al., bioRxiv - Neuroscience 2024

  Quote: ... co-staining IBA-1 – ZO-1 incubation during 24 h at room temperature (1:1000, ab178846, rabbit anti-IBA-1, Abcam; 1:200, sc-33725, rat anti-ZO-1, Santa Cruz Biotechnology); and GFAP incubation during 24 h at room temperature (1:1000 ...
• NMNAT promotes glioma growth through regulating post-translational modifications of p53 to inhibit apoptosis

  Jiaqi Liu, et al., bioRxiv - Cancer Biology 2021

  Quote: ... p53(DO-1) (1:1000, Santa Cruz, sc-126), anti-Drosophila Nmnat (1:3000) ...
• Krüppel-like factor 2- induced microRNAs: implications for treatment of pulmonary hypertension

  Hebah Sindi, et al., bioRxiv - Cell Biology 2019

  Quote: ... ETS-1 (1:1000; Santa Cruz Biotechnology, sc-55581), α-SMA (1:1000 ...
• Retroviral Infection of Human Neurospheres and Use of Stem Cell EVs to Repair Cellular Damage

  Heather Branscome, et al., bioRxiv - Cell Biology 2021

  Quote: ... α-IBA-1 (Santa Cruz Biotechnology sc-32725; 1:200), α-TNFα (Santa Cruz Biotechnology sc-52749 ...
• Retroviral Infection of Human Neurospheres and Use of Stem Cell EVs to Repair Cellular Damage

  Heather Branscome, et al., bioRxiv - Cell Biology 2021

  Quote: ... α-PARP-1 (Santa Cruz Biotechnology sc-7150; 1:200), α-Caspase 3 (Santa Cruz Biotechnology sc-7148 ...
• Retroviral Infection of Human Neurospheres and Use of Stem Cell EVs to Repair Cellular Damage

  Heather Branscome, et al., bioRxiv - Cell Biology 2021

  Quote: ... α-IBA-1 (Santa Cruz Biotechnology sc-32725; 1:50), α-Tubulin β 3 (Tuj1 ...
• Myocardial matrix material supports a proliferative microenvironment for cardiomyocytes

  Raymond M. Wang, et al., bioRxiv - Bioengineering 2020

  Quote: ... mouse PCM-1 (1:200, Santa Cruz, sc-398365), α-actinin (1:800 ...
• ECSIT prevents Alzheimer’s disease pathology by regulating neuronal mitochondrial ROS and mitophagy

  Alice Lepelley, et al., bioRxiv - Neuroscience 2020

  Quote: ... HSP60 (1:500, Santa Cruz Biotechnology, clone H-1), GAPDH (1:5,000 ...
• Chromosomally unstable tumor cells specifically require KIF18A for proliferation

  Carolyn Marquis, et al., bioRxiv - Cell Biology 2020

  Quote: ... mouse anti-centrin-1 1:500 (Santa Cruz Biotechnology) for one hour at RT ...
• Pharmacological PP2A reactivation overcomes multikinase inhibitor tolerance across brain tumor cell models

  Oxana V. Denisova, et al., bioRxiv - Cancer Biology 2022

  Quote: ... PME-1 (Santa Cruz Biotechnology, sc-20086, 1:1000), phospho PDHE1α S300 (Millipore ...
• Aiolos modulates the T_FH and CD4-CTL differentiation programs via reciprocal regulation of the Zfp831/TCF-1/Bcl-6 axis and CD25

  Kaitlin A. Read, et al., bioRxiv - Immunology 2022

  Quote: ... mouse anti-rabbit:HRP (Santa Cruz, 1:5000-1:20,000).
• Gli3 regulates vomeronasal neurogenesis, olfactory ensheathing cell formation and GnRH-1 neuronal migration

  Ed Zandro M. Taroc, et al., bioRxiv - Developmental Biology 2019

  Quote: ... and mouse-α-Ascl-1 (1:30, Santa Cruz). Antigen retrieval was performed in a citrate buffer prior to incubation with chicken-α-peripherin ...
• Human DICER helicase domain recruits PKR and modulates its antiviral activity

  Thomas C. Montavon, et al., bioRxiv - Microbiology 2021

  Quote: ... anti-hADAR-1 (1:500 Santa Cruz sc-271854) anti-p-PKR (1:1000 Abcam ab81303 ...
• Nuclear Hormone Receptor NHR-49 controls a HIF-1-independent hypoxia adaptation pathway in Caenorhabditis elegans

  Kelsie R. S. Doering, et al., bioRxiv - Genetics 2021

  Quote: ... 1 mM IPTG (Santa Cruz CAS 367-93-1), and 12.5 μg/ml tetracycline (BioBasic TB0504 (NGM-RNAi plates) ...
• CRISPR-mediated correction of skeletal muscle Ca²⁺ handling in a novel DMD patient-derived pluripotent stem cell model

  Cristina Morera, et al., bioRxiv - Cell Biology 2022

  Quote: ... Tra-1-60 (Santa Cruz, sc-21705; 1:100), SSEA4 (BD Bioscience ...
• Ketosis Prevents Abdominal Aortic Aneurysm Rupture Through CCR2 Downregulation and Enhanced MMP Balance

  Sergio Sastriques-Dunlop, et al., bioRxiv - Pathology 2023

  Quote: ... and Caveolin-1 (Santa Cruz # sc-53564, 1:1000) were used as loading controls ...
• Establishment of Bovine Trophoblast Stem Cells

  Yinjuan Wang, et al., bioRxiv - Developmental Biology 2022

  Quote: ... anti-PL-1(Santa Cruz, sc-376436; 1:200) and anti-PTGS2 (Sigma ...
• LOX-1 and MMP-9 inhibition attenuates the detrimental effects of delayed rt-PA therapy and improves outcomes after acute ischemic stroke

  Kajsa Arkelius, et al., bioRxiv - Neuroscience 2023

  Quote: ... VCAM-1 (1:500 #sc-13160 Santa Cruz Biotechnology), diluted in 5% bovine serum albumin (BSA ...
• BET inhibition rescues ciliogenesis and ameliorates pancreatitis-driven phenotypic changes in mice with Par3 loss

  Mario A. Shields, et al., bioRxiv - Pathology 2023

  Quote: ... Zo-1 (Santa Cruz Biotech #sc-33725, 1:200), Amylase (Santa Cruz Biotech #sc-46657 ...