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7351 - 7400 of 8862 citations for 6 1 4 dioxa 8 azaspiro 4.5 decan 8 yl 3 hydroxy 2 iminopyrimidin 4 amine since 2019

• The metabolic enzyme EXT1 is sufficient to induce the epithelial-mesenchymal transition program in cancers

  Balakrishnan Solaimuthu, et al., bioRxiv - Cancer Biology 2023

  Quote: Antibodies were obtained from the following sources: EXT-1 (sc-515144) from Santa Cruz Biotechnology ...
• A flexible loop in the paxillin LIM3 domain mediates direct binding to integrin β3

  Timo Baade, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-human FAK (rabbit polyclonal, A-17, Santa Cruz, sc-557; WB 1:250), anti-human kindlin2 (mouse monoclonal ...
• The phosphodiesterase 2A regulates lymphatic endothelial development via cGMP-mediated control of Notch signaling

  Claudia Carlantoni, et al., bioRxiv - Developmental Biology 2023

  Quote: ... goat anti-VE-cadherin (C19 clone, Cat#: sc-6458, Santa Cruz Biotechnologies, 1:250), goat anti-VE-cadherin (Cat# ...
• Ancient and nonuniform loss of olfactory receptor expression renders the shark nose a de facto vomeronasal organ

  Adnan S. Syed, et al., bioRxiv - Evolutionary Biology 2022

  Quote: ... anti-Go (K-20) antibody (rabbit IgG; 1:50; sc-387, Santa Cruz Biotechnology). Secondary antibodies used were goat anti-rabbit IgG conjugated to Alexa Fluor 488 (A21206 ...
• Label-free and high-throughput removal of residual undifferentiated cells from iPSC-derived spinal-cord progenitor cells

  Tan Dai Nguyen, et al., bioRxiv - Bioengineering 2023

  Quote: ... The primary antibodies used were: OCT4 (1:500, sc-5279, Santa Cruz Biotechnology, USA) and SOX1 (1:500 ...
• A novel mechanobiological model of bone metastasis reveals that mechanical stimulation inhibits the pro-osteoclastogenic effects of breast cancer cells

  Vatsal Kumar, et al., bioRxiv - Bioengineering 2023

  Quote: ... anti-αvβ3 antibody directly conjugated to Alexa Fluor® 488 (1:100) (Santa Cruz) was utilized ...
• Lineage tracing identifies heterogeneous hepatoblast contribution to cell lineages and postembryonic organ growth dynamics

  Iris. A. Unterweger, et al., bioRxiv - Developmental Biology 2023

  Quote: Primary antibodies included: α-Hnf4α (goat polyclonal antibody, 1:100, Santa Cruz, sc-6556); α-mCherry (rat monoclonal antibody ...
• CHAF1A promotes the translesion DNA synthesis pathway in response to DNA replication stress

  Bing Wen, et al., bioRxiv - Cell Biology 2023

  Quote: ... and goat anti-rabbit IgG-HRP antibodies (sc-2030, Santa Cruz Biotechnology; 1:5000).
• CHAF1A promotes the translesion DNA synthesis pathway in response to DNA replication stress

  Bing Wen, et al., bioRxiv - Cell Biology 2023

  Quote: ... Secondary antibodies included goat anti-mouse IgG-HRP (sc-2005, Santa Cruz; 1:5000) and goat anti-rabbit IgG-HRP antibodies (sc-2030 ...
• CHAF1A promotes the translesion DNA synthesis pathway in response to DNA replication stress

  Bing Wen, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse monoclonal anti-PCNA (sc-56, Santa Cruz Biotechnology, Dallas, TX, USA; 1:1000), rabbit monoclonal anti-Ub-PCNA (K164 ...
• RAD52 prevents accumulation of Polα-dependent replication gaps at perturbed replication forks in human cells

  Ludovica Di Biagi, et al., bioRxiv - Cell Biology 2023

  Quote: ... Blots were incubated with primary antibodies against: anti-GFP (Santa Cruz Biotechnology, 1:500), anti-MUS81 (Santa Cruz Biotechnology ...
• β-actin is essential for structural integrity and physiological function of the retina

  Pavan Vedula, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse anti-rhodopsin (1:100 dilution, clone 1D4, sc-57432, Santa Cruz Biotechnology Inc.).
• Pathways that affect anterior morphogenesis in C. elegans embryos

  Balasubramaniam Boopathi, et al., bioRxiv - Developmental Biology 2023

  Quote: ... followed by staining with mouse monoclonal anti-GFP (1:300, Santa Cruz #sc-9996) in 0.5% milk in PBS for 1 hour at room temperature ...
• Parsing the effect of co-culture with brain organoids on Diffuse Intrinsic Pontine Glioma (DIPG) using quantitative proteomics

  Victoria G Prior, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Primary antibodies for staining included vimentin (1/100 dilution, Santa Cruz Biotechnology, TX, USA), SOX2 (1/200 dilution ...
• DISTINCT ROLES OF VIRAL US3 AND UL13 PROTEIN KINASES IN HERPES VIRUS SIMPLEX TYPE 1 (HSV-1) NUCLEAR EGRESS

  Masoudeh Masoud Bahnamiri, Richard J. Roller, bioRxiv - Microbiology 2023

  Quote: ... and probed for emerin using mouse monoclonal anti-emerin (1:500) (Santa Cruz Biotechnology). The membranes were then incubated with the respective alkaline phosphatase- conjugated secondary antibodies for 1 hour and developed in western blotting (WB ...
• Tunable DNMT1 degradation reveals cooperation of DNMT1 and DNMT3B in regulating DNA methylation dynamics and genome organization

  Andrea Scelfo, et al., bioRxiv - Molecular Biology 2023

  Quote: ... The following antibodies were used for immunoblotting: DNMT1 (1:100, Santa Cruz sc-271729); DNMT3B (1:1000 ...
• A Rapid Inducible RNA Decay system reveals fast mRNA decay in P-bodies

  Lauren A. Blake, Yang Liu, Takanari Inoue, Bin Wu, bioRxiv - Molecular Biology 2023

  Quote: ... or 1:250 rabbit anti-Ribosomal Protein S3 primary antibody (Santa Cruz sc-376008) as a control ...
• Effects of the G-quadruplex-binding drugs Quarfloxin and CX-5461 on the malaria parasite Plasmodium falciparum

  Holly M. Craven, et al., bioRxiv - Microbiology 2023

  Quote: ... BrdU was detected with 1:500 mouse anti BrdU (MoBU sc-51514, Santa Cruz) and 1U nuclease in 1% BSA ...
• Fasciola hepatica GST mu-class suppresses the cytokine storm induced by E. coli-lipopolysaccharide whereas modulates the dynamic of peritoneal macrophages in a mouse model and suppresses the classical activation of macrophages

  Bianca N. Valdes-Fernandez, et al., bioRxiv - Microbiology 2023

  Quote: ... or a mouse anti-ARG-1 IgG antibody labeled with FITC (Santa Cruz Biotechnology) diluted 1:100 ...
• A ubiquitin-proteasome pathway degrades the inner nuclear membrane protein Bqt4 to maintain nuclear membrane homeostasis

  Toan Khanh Le, et al., bioRxiv - Cell Biology 2023

  Quote: ... and an anti-ubiquitin mouse monoclonal antibody (P4D1, 1:1000; Santa Cruz Biotechnology, USA). Protein levels in the input samples were assessed using an anti-β-actin antibody (1:2000 ...
• Atrial t-tubules adopt a specialist developmental state while alterations to Ca²⁺ buffering maintain systolic Ca²⁺ during postnatal development

  CER Smith, et al., bioRxiv - Physiology 2023

  Quote: ... Membranes were incubated with primary antibodies targeted to AMPII (1:200, Santa Cruz Biotechnology), JPH2 (1:5000 ...
• Elucidating the Synergistic Role of Elm1 and Gin4 Kinases in Regulating Septin Hourglass Assembly

  Joseph Marquardt, Xi Chen, Erfei Bi, bioRxiv - Cell Biology 2023

  Quote: ... and mouse anti-Cdc28 (1:3000 dilution, sc-515762, Santa Cruz, Dallas, TX, USA) primary antibodies ...
• PRDM3/16 Regulate Chromatin Accessibility Required for NKX2-1 Mediated Alveolar Epithelial Differentiation and Function

  Hua He, et al., bioRxiv - Developmental Biology 2023

  Quote: Primary antibodies used include: Mouse anti-HOP (Santa Cruz Biotechnology sc-398703; 1:100), Guinea Pig anti-pro-SFTPC (In house ...
• Identification of SIRT4 as a novel paralog-specific interactor and candidate suppressor of C-RAF kinase in MAPK signaling

  Mehrnaz Mehrabipour, et al., bioRxiv - Biochemistry 2023

  Quote: ... anti-C-RAF-pY340/341 (1:1000; #sc-16806, Santa Cruz Biotechnology, Heidelberg, Germany); anti-Vinculin (1:1000 ...
• Reprogramming early cortical astroglia into neurons with hallmarks of fast-spiking parvalbumin-positive interneurons by phospho-site deficient Ascl1

  Nicolás Marichal, et al., bioRxiv - Neuroscience 2023

  Quote: ... The following primary antibodies were used: anti-Doublecortin (Dcx, goat, 1:250, Santa Cruz Biotechnology ...
• Hyperactive PI3Kinase delta enables long distance regeneration of the rat corticospinal tract

  Kristyna Karova, et al., bioRxiv - Neuroscience 2023

  Quote: ... mouse anti-PKCγ (1:1000, Santa Cruz, Dallas, TX, USA, sc166451 A-7 clone), mouse anti-cFOS (1:500 ...
• Mapping RNA-Protein Interactions with Subcellular Resolution Using Colocalization CLIP

  Soon Yi, et al., bioRxiv - Molecular Biology 2023

  Quote: ... Antibodies used for immunofluorescence were: HuR 3A2 (Santa Cruz, cat. #sc-5261, 1:1000), FLAG M2 (Sigma ...
• AKAP150-anchored PKA regulation of synaptic transmission and plasticity, neuronal excitability and CRF neuromodulation in the lateral habenula

  S.C. Simmons, et al., bioRxiv - Neuroscience 2023

  Quote: ... Sections were incubated in goat anti-AKAP150 antibody (1:500, Santa Cruz Sc-6445) in carrier solution (5 % NGS in 0.1% Triton X-100 in 1x PBS ...
• Death Induced by Survival gene Elimination (DISE) is correlated with neurotoxicity in Alzheimer’s disease and aging

  Bidur Paudel, et al., bioRxiv - Neuroscience 2023

  Quote: ... HRP-conjugated β-actin (C4) mouse mAb (Santa Cruz Biotechnology #Sc-47778, 1:10,000), phospho-histone H2A.X (Ser139 ...
• The Cardiac Calcium Handling Machinery is Remodeled in Friedreich’s Ataxia

  Roman Czornobil, et al., bioRxiv - Physiology 2023

  Quote: ... and mouse monoclonal anti-Ryr2 (dilution 1:1000; Santa Cruz Biotechnology; Catalog # sc-376507), mouse monoclonal anti-SERCA2a (dilution 1:500 ...
• An actomyosin network organizes niche morphology and responds to feedback from recruited stem cells

  Bailey N. Warder, et al., bioRxiv - Developmental Biology 2023

  Quote: ... We used Goat antibody against Vasa 1:400 (Santa Cruz, dC-13, now discontinued); Rabbit antibody against STAT92E 1:350 (gift from E ...
• Host E3 ubiquitin ligase ITCH mediates Toxoplasma gondii effector GRA35-triggered NLRP1 inflammasome activation and cell-autonomous immunity

  Yifan Wang, et al., bioRxiv - Immunology 2023

  Quote: ... Antibodies used include: Ubiquitin mouse monoclonal Ab (1:2000, Santa Cruz Biotechnology, sc-8017), ITCH goat Ab (1:2000 ...
• Anti- and pro-inflammatory milieu differentially regulate differentiation and immune functions of oligodendrocyte progenitor cells

  Omri Zveik, et al., bioRxiv - Immunology 2023

  Quote: ... and anti-IBL-5/22(Cat#sc-59,322, RRID:AB_831551, Santa Cruz Biotechnology, 1:100) for evaluation of MHC-II expression ...
• Sensory progenitors influence patterning of the mammalian auditory sensory epithelium

  Caryl A. Young, Emily Burt, Vidhya Munnamalai, bioRxiv - Developmental Biology 2023

  Quote: ... goat anti-Jagged1 (1:250, sc-6011, Lot# I2115 Santa Cruz Biotechnology, CA, USA), rat anti-Ki67 (1:250 ...
• The CD36 scavenger receptor Bez regulates lipid redistribution from fat body to oocytes in Drosophila

  Pilar Carrera, et al., bioRxiv - Developmental Biology 2023

  Quote: ... The following additional primary antibodies were used: rabbit anti-GFP (1:100; Santa Cruz), mouse anti-RFP (1:200 ...
• Dia2 formin controls receptor activity by organizing plasma membrane lipid partitioning at the nanoscale

  Changting Li, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse anti-DAAM1 (Santa Cruz Bio, cat. no. sc-100942; 1:1000 for WB); mouse anti-FHOD1 (Santa Cruz Bio ...
• Dia2 formin controls receptor activity by organizing plasma membrane lipid partitioning at the nanoscale

  Changting Li, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse anti-FMNL1 (Santa Cruz Bio, cat. no. sc-390023; 1:1000 for WB); mouse anti-FMNL2 (Santa Cruz Bio ...
• Dia2 formin controls receptor activity by organizing plasma membrane lipid partitioning at the nanoscale

  Changting Li, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse anti-FHOD1 (Santa Cruz Bio, cat. no. sc-365437; 1:1000 for WB); mouse anti-FMNL1 (Santa Cruz Bio ...
• Dia2 formin controls receptor activity by organizing plasma membrane lipid partitioning at the nanoscale

  Changting Li, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse anti-FMNL2 (Santa Cruz Bio, cat. no. sc-390298; 1:1000 for WB); mouse anti-α-tubulin (clone B512 ...
• Molecular Regulation of Invasive Protrusion Formation at the Mammalian Fusogenic Synapse

  Yue Lu, et al., bioRxiv - Cell Biology 2023

  Quote: ... The following primary antibodies were used: mouse anti-WASP (1:1000; Santa Cruz; 4860), rabbit anti-N-WASP (1:1000 ...
• A Humanized Yeast System for Evaluating the Protein Prenylation of a Wide Range of Human and Viral CaaX Sequences

  Emily R. Hildebrandt, et al., bioRxiv - Biochemistry 2023

  Quote: ... mouse anti-c-Myc 9E10 monoclonal (1:1000 dilution, Santa Cruz Biotech. #sc-40); mouse anti-GFP B-2 monoclonal (1:500 ...
• Chromosome 8 gain drives cancer progression by hijacking the translation factor 4E-BP1 sensitizing for targeted CDK4/6 inhibition

  Cornelius M. Funk, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Anti-rabbit IgG horseradish peroxidase coupled antibody (1:2,000, sc-516102, Santa Cruz Biotechnology) and anti-mouse IgG horseradish peroxidase coupled antibody (1:2,000 ...
• An interactive cellular ecosystem blocks epithelial transformation in naked mole-rat

  Mikaela Behm, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Tumouroids were gently rinsed with PBS and then fixed with 1% PFA (Santa Cruz) for 15 minutes on ice in the dark ...
• Folding correctors can restore CFTR posttranslational folding landscape by allosteric domain-domain coupling

  Naoto Soya, et al., bioRxiv - Biophysics 2023

  Quote: ... Anti-Na/K-ATPase Ab (1:5000, #SC- 48345) was purchased from Santa Cruz Biotechnology ...
• Aryl amino acetamides prevent the development of Plasmodium falciparum rings via inhibition of the lipid transfer protein PfSTART1

  Madeline G. Dans, et al., bioRxiv - Cell Biology 2023

  Quote: ... Imaging medium was prepared by adding 10 μM Trolox (Santa Cruz 53188-07-1) to the culture medium ...
• Drug-Induced p53 Activation Promotes Acinar Cell Identity and Prevents Pancreatic Cancer Initiation

  Jennifer J Twardowski, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Primary antibodies included mouse monoclonal anti-AMYLASE (Santa Cruz Biotechnology sc-46657, 1:100), rabbit monoclonal anti-MIST1 (Cell Signaling Technology 14896T ...
• A kinetochore-centrosome feedback loop linking CENP-E and Aurora kinases controls chromosome biorientation and congression

  Kruno Vukušić, Iva M. Tolić, bioRxiv - Cell Biology 2024

  Quote: ... and mouse monoclonal anti-KID (B-9, sc-390640, Santa Cruz, diluted 1:500).
• Nuclear receptor E75/NR1D2 drives tumor malignant transformation by integrating Hippo and Notch pathways

  Xianping Wang, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Primary antibodies used in mammalian cells include mouse anti-NR1D2 (Santa Cruz, 1:100), rabbit anti-TAZ ...
• BRAT1 - a new therapeutic target for glioblastoma

  Alicia Haydo, et al., bioRxiv - Cancer Biology 2024

  Quote: ... and 1 µg/mL Puromycin dihydrochloride (sc-108071B, Lot # L2214, Santa Cruz Biotechnology, Inc.). Both cell lines were cultured at 37°C and 5% CO2 and were passaged twice a week in a ratio of 1:10 or 1:20 ...
• Human ADA2 deficiency is characterized by the absence of an intracellular hypoglycosylated form of adenosine deaminase 2

  Lisa Ehlers, et al., bioRxiv - Immunology 2024

  Quote: ... anti-CD98 (clone E-5, #sc-376815, 1:500; Santa Cruz Biotechnology; RRID: AB_2938854), anti-GAPDH (clone 7B ...