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7301 - 7350 of 8862 citations for 6 1 4 dioxa 8 azaspiro 4.5 decan 8 yl 3 hydroxy 2 iminopyrimidin 4 amine since 2019

• hnRNP R is a regulator of stress granule formation

  Changhe Ji, bioRxiv - Neuroscience 2022

  Quote: ... 10 µl Dynabeads Protein G and 1 µg RPS5 antibody (Santa Cruz, sc-390935) or mouse IgG control were added to 200 µl lysis buffer and rotated for 30-40 min at RT ...
• Constitutive 5-HT2C receptor knock-out facilitates fear extinction through altered activity of a dorsal raphe-bed nucleus of the stria terminalis pathway

  Sandra T. Süß, et al., bioRxiv - Neuroscience 2022

  Quote: ... and mouse anti cFos (1:500, sc-271243, Santa Cruz Biotechnology, Dallas, TX, USA)) containing 5 % NDS in 0.3 % PBS-T for ∼17 h at 4 °C ...
• Constitutive 5-HT2C receptor knock-out facilitates fear extinction through altered activity of a dorsal raphe-bed nucleus of the stria terminalis pathway

  Sandra T. Süß, et al., bioRxiv - Neuroscience 2022

  Quote: ... and mouse anti cFos (1:500, sc-271243, Santa Cruz Biotechnology, Dallas, TX, USA)) consisting of 3 % NDS in 0.3 % PBS-T for ∼38 h at 4 °C ...
• Induced pluripotent stem cell-derived astrocytes from patients with schizophrenia exhibit an inflammatory phenotype that affects vascularization

  Pablo Trindade, et al., bioRxiv - Neuroscience 2022

  Quote: ... and mouse anti-NF-κB p65 (1:100; sc-8008, Santa Cruz Biotechnology, USA). Subsequently ...
• Diet prevents the expansion of segmented filamentous bacteria and ileo-colonic inflammation in a model of Crohn’s disease

  Amira Metwaly, et al., bioRxiv - Microbiology 2022

  Quote: ... Sections were co-stained with anti-MUC2 (H-300, 1:100, Santa Cruz Biotechnology) for 1h at RT following 30 min of incubation with secondary antibody (1:200 ...
• An immunoresponsive three-dimensional urine-tolerant human urothelial (3D-UHU) model to study urinary tract infection

  Nazila V. Jafari, Jennifer L. Rohn, bioRxiv - Microbiology 2022

  Quote: ... mouse anti-uroplakin-III (UPKIII) monoclonal antibody (1:50 dilution, sc-166808, Santa Cruz); mouse anti-cytokeratin 8 (CK8 ...
• Mapping PTBP splicing in human brain identifies targets for therapeutic splice switching including SYNGAP1

  Jennine M. Dawicki-McKenna, et al., bioRxiv - Molecular Biology 2022

  Quote: ... previously validated6 and mouse anti-ATP5F1 (Abcam #ab117991, 1:1000 dilution or Santa Cruz Biotechnology #sc-514419 ...
• Hepatocyte-specific loss of LAP2α protects against diet-induced hepatic steatosis and steatohepatitis in male mice

  Kapil K. Upadhyay, et al., bioRxiv - Physiology 2022

  Quote: ... anti-lamin A/C (1:100, sc-376248, Santa Cruz Biotechnology, Santa Cruz, CA) and Alexa Fluor 488 rabbit anti-mouse IgG (H+ L ...
• Hepatocyte-specific loss of LAP2α protects against diet-induced hepatic steatosis and steatohepatitis in male mice

  Kapil K. Upadhyay, et al., bioRxiv - Physiology 2022

  Quote: ... anti-lamin A/C (1:100, sc-376248, Santa Cruz Biotechnology, Santa Cruz, CA) and Alexa Fluor 488 rabbit anti-mouse IgG (H+ L ...
• Assessment of urinary exosome NHE3 as a biomarker of acute kidney injury

  Yanting Yu, et al., bioRxiv - Molecular Biology 2022

  Quote: ... The chemo-luminal signals from HRP-conjugated secondary antibodies (1:10000, Santa Cruz, CA) were exposed onto x-ray film ...
• Targeting neuroinflammation with Abscisic Acid reduces pain sensitivity in females and hyperactivity in males of an ADHD mice model

  Maria Meseguer-Beltrán, et al., bioRxiv - Neuroscience 2022

  Quote: ... and mouse anti-Ref1/Ape1 (Santa Cruz Biotechnology, Santa Cruz, CA, USA; 1:200) were incubated overnight ...
• Antagonism between viral infection and innate immunity at the single-cell level

  Frederic Grabowski, et al., bioRxiv - Systems Biology 2022

  Quote: ... anti-PKR (clone B-10) (catalog number sc-6282; Santa Cruz Biotechnology; 1:1000); anti-RNase L (clone E-9 ...
• CHK2 Regulates MUS81-EME2 Function in Response to Replication Stress and BRCA2 Deficiency

  Eva Malacaria, et al., bioRxiv - Cell Biology 2022

  Quote: Blots were incubated with primary antibodies against: anti-MUS81 (Santa Cruz Biotechnology, 1:2000), anti-Lamin B1 (Abcam ...
• MagIC-Cryo-EM: Structural determination on magnetic beads for scarce macromolecules in heterogeneous samples

  Yasuhiro Arimura, et al., bioRxiv - Molecular Biology 2024

  Quote: ... 1 µg/mL of mouse monoclonal Anti-GFP Antibody sc-9996 (Santa Cruz Biotechnology) and as secondary antibodies ...
• Dnmt3a1 regulates hippocampus-dependent memory via the downstream target Nrp1

  Janina Kupke, et al., bioRxiv - Neuroscience 2024

  Quote: ... cells were incubated with primary antibody α-Dnmt3a (1:500, H-295, Santa Cruz, SC-20703diluted in PBS containing 2% BSA ...
• Transcriptional Regulation of Protein Synthesis by Mediator Kinase in MYC-driven Medulloblastoma

  Dong Wang, et al., bioRxiv - Cancer Biology 2024

  Quote: ... The following antibodies were used: Phospho-4EBP1 (Santa Cruz Biotechnology, sc-293124, 1:50), CDK8 (Santa Cruz Biotechnology ...
• “Non-viral CRISPR/Cas9 Mutagenesis for Streamlined Generation of Mouse Lung Cancer Models.”

  Irene Lara-Saez, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-CC10 H-75 (sc-25554, Santa Cruz Biotechnology, Dallas, TX, USA, 1:300); anti-synaptophysin SY38 (ab8049 ...
• Dysregulation of the p53 pathway provides a therapeutic target in aggressive pediatric sarcomas with stem-like traits

  Lucie Curylova, et al., bioRxiv - Cancer Biology 2024

  Quote: ... mouse anti-MDM2 (1:500; #sc-965, Santa Cruz Biotechnology, SCBT, Dallas, TX, USA), mouse anti-p63 (1:200 ...
• A VHL-1;HIF-1/SQRD1/COL-88 axis links extracellular matrix formation with longevity in Caenorhabditis elegans

  Willian Salgueiro, et al., bioRxiv - Genetics 2024

  Quote: ... Staining was performed using an anti GFP antibody (Santa Cruz, sc-8334, 1:5,000) and an anti-rabbit secondary antibody (1:15,000 ...
• AQP1 Differentially Orchestrates Endothelial Cell Senescence

  Khatereh Shabanian, et al., bioRxiv - Molecular Biology 2024

  Quote: ... antibody against H3ac (Pan-Acetyl) (1:500; sc-518011) was obtained from Santa Cruz Biotechnology ...
• Impact of juglone on oral carcinogenesis induced by 4-nitroquinoline-1-oxide (4NQO) in rat model

  Olgun Topal, et al., bioRxiv - Pharmacology and Toxicology 2024

  Quote: ... Horseradish peroxidase-conjugated secondary antibody (Santa Cruz, sc:2030 or sc:2770, 1:10,000) was incubated for 1 h ...
• A direct estrogenic involvement in the expression of human hypocretin

  Haimei Li, et al., bioRxiv - Neuroscience 2023

  Quote: ... The purified primary antibody against hypocretin (1:400, sc-80263, Santa Cruz Biotechnology, USA) in 1% BSA was incubated overnight at 4°C ...
• A targeted CRISPR-Cas9 mediated F0 screen identifies genes involved in establishment of the enteric nervous system

  Rodrigo Moreno-Campos, et al., bioRxiv - Neuroscience 2023

  Quote: ... Mouse monoclonal IgG1 anti-Phox2b (B-11, Santa Cruz Biotechnology, SC-376997, 1:250). The following secondary antibodies were used from Invitrogen ...
• Inflammatory pain resolution by mouse serum-derived small extracellular vesicles

  Zhucheng Lin, et al., bioRxiv - Neuroscience 2024

  Quote: ... Primary antibodies used were: mouse anti-CD81 (1:500, #sc-166029, Santa Cruz Biotechnology), rabbit anti-Hsp70 (1:2000 ...
• High Shear Stress Reduces ERG Causing Endothelial-Mesenchymal Transition and Pulmonary Arterial Hypertension

  Tsutomu Shinohara, et al., bioRxiv - Cell Biology 2024

  Quote: ... Slides were incubated with rabbit antibodies targeting KLF4 (1:100, sc20691, Santa Cruz Biotechnology) and mouse antibodies targeting ERG (1:100 ...
• FoxO transcription factors actuate the formative pluripotency specific gene expression programme

  Laura Santini, et al., bioRxiv - Developmental Biology 2024

  Quote: ... and 1:10,000 for anti-Vinculin(H-10) (mouse; Santa Cruz Biotechnology, sc-25336). Secondary antibodies were diluted in 5% milk and used 1:10,000 for anti-rabbit IgG (Amersham ...
• Expansion of a neural crest gene signature following ectopic MYCN expression in sympathoadrenal lineage cells in vivo

  Rodrigo Ibarra-García-Padilla, et al., bioRxiv - Developmental Biology 2024

  Quote: ... and mouse monoclonal IgG1 anti-Phox2b (72) (Santa Cruz Biotechnology, SC-376997, 1:250). Secondary antibodies and concentrations used were Alexa Fluor 488 goat anti-rabbit IgG (H+L ...
• A Synergistic Desmin-SPARC Axis Influences Cardiac Stem Cell Differentiation and Promotes Cardiomyogenesis through Autocrine Regulation

  Lucia Leitner, et al., bioRxiv - Developmental Biology 2024

  Quote: ... SPARC was detected with rabbit anti-SPARC antibody (#sc-25574, Santa Cruz, 1:200) and secondary alkaline phosphatase-conjugated anti-rabbit IgG antibody (#111-035-003 ...
• Human hnRNPA1 reorganizes telomere-bound Replication Protein A

  Sophie L. Granger, et al., bioRxiv - Biophysics 2024

  Quote: ... and incubated with 1 μg of anti-hnRNPA1 antibody (Santa Cruz Biotech, sc-32301) overnight at 4 °C with constant rotation ...
• Molecular Regulation of Invasive Protrusion Formation at the Mammalian Fusogenic Synapse

  Yue Lu, et al., bioRxiv - Cell Biology 2023

  Quote: ... The following primary antibodies were used: mouse anti-WASP (1:1000; Santa Cruz; 4860), rabbit anti-N-WASP (1:1000 ...
• An actomyosin network organizes niche morphology and responds to feedback from recruited stem cells

  Bailey N. Warder, et al., bioRxiv - Developmental Biology 2023

  Quote: ... We used Goat antibody against Vasa 1:400 (Santa Cruz, dC-13, now discontinued); Rabbit antibody against STAT92E 1:350 (gift from E ...
• The CD36 scavenger receptor Bez regulates lipid redistribution from fat body to oocytes in Drosophila

  Pilar Carrera, et al., bioRxiv - Developmental Biology 2023

  Quote: ... The following additional primary antibodies were used: rabbit anti-GFP (1:100; Santa Cruz), mouse anti-RFP (1:200 ...
• Sensory progenitors influence patterning of the mammalian auditory sensory epithelium

  Caryl A. Young, Emily Burt, Vidhya Munnamalai, bioRxiv - Developmental Biology 2023

  Quote: ... goat anti-Jagged1 (1:250, sc-6011, Lot# I2115 Santa Cruz Biotechnology, CA, USA), rat anti-Ki67 (1:250 ...
• Calcium signals tune AMPK activity and mitochondrial homeostasis in dendrites of developing neurons

  Akane Hatsuda, et al., bioRxiv - Neuroscience 2023

  Quote: ... and HRP-conjugated mouse anti-beta actin (1:10000, Santa Cruz, sc-47778 HRP). The secondary antibodies used were the following ...
• Differentiated Oral Epithelial Cells Support the HPV Life Cycle

  William T Seaman, et al., bioRxiv - Microbiology 2023

  Quote: ... and HPV L1 was detected with CAMVIR-1 antibody (sc-47699; Santa Cruz Biotech). Fixed cells were overlaid with 1:500 dilution of primary antibody and incubated overnight at 4° C ...
• Transcription regulation of SARS-CoV-2 receptor ACE2 by Sp1: a potential therapeutic target

  Hui Han, et al., bioRxiv - Microbiology 2023

  Quote: ... and anti-Actin antibodies (sc- 47778, 1:5000 dilution, Santa Cruz-Biotechnology, Shanghai, China). After washed with PBS- T ...
• Palmitoylethanolamide shows limited efficacy in controlling cerebral cryptococcosis in vivo

  Melissa E. Munzen, et al., bioRxiv - Microbiology 2023

  Quote: ... FujiFilm Wako) specific Ab (conjugated to horseradish peroxidase; dilution: 1:1,000; Santa Cruz Biotechnology) immunostaining to assess capsular release and distribution and microglial phenotype ...
• Shared GABA transmission pathology in dopamine agonist- and antagonist-induced dyskinesia

  Yoshifumi Abe, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-rhodopsin (1:500 dilution; mouse monoclonal, 1D4, Santa Cruz Biotechnology, Dallas, TX, USA), anti-GFP (1:250 dilution ...
• Effects of the G-quadruplex-binding drugs Quarfloxin and CX-5461 on the malaria parasite Plasmodium falciparum

  Holly M. Craven, et al., bioRxiv - Microbiology 2023

  Quote: ... BrdU was detected with 1:500 mouse anti BrdU (MoBU sc-51514, Santa Cruz) and 1U nuclease in 1% BSA ...
• Fasciola hepatica GST mu-class suppresses the cytokine storm induced by E. coli-lipopolysaccharide whereas modulates the dynamic of peritoneal macrophages in a mouse model and suppresses the classical activation of macrophages

  Bianca N. Valdes-Fernandez, et al., bioRxiv - Microbiology 2023

  Quote: ... or a mouse anti-ARG-1 IgG antibody labeled with FITC (Santa Cruz Biotechnology) diluted 1:100 ...
• Somatic mutation of Afadin leads to anchorage independent survival and metastatic growth of breast cancer through αE-catenin dependent destabilization of the adherens junction

  Max A.K. Ratze, et al., bioRxiv - Cancer Biology 2023

  Quote: ... The following primary antibodies were used: mouse anti-p120 6H11 (1:500; Santa Cruz Biotechnology ...
• MEK1/2-Targeting PROTACs Promote the Collateral Degradation of CRAF in KRAS Mutant Cells

  Carlos Herrera-Montávez, et al., bioRxiv - Cancer Biology 2023

  Quote: ... then 1 mg protein was precleared using normal mouse IgG agarose conjugate (Santa Cruz) for 2-4 hours at 4°C ...
• A simplified and rapid in situ hybridization protocol for planarians

  Andrew J. Gaetano, Ryan S. King, bioRxiv - Developmental Biology 2023

  Quote: ... Ciliated protonephridia were labeled with 1:1,000 anti-acetylated-alpha tubulin (Santa Cruz Biotech) and 1:500 Alexa 488 anti-mouse (Thermo Fisher) ...
• Conductive microgel annealed scaffolds enhance myogenic potential of myoblastic cells

  Alena Casella, et al., bioRxiv - Bioengineering 2023

  Quote: ... and myogenin antibody conjugated with Alexa Fluor 680 (1:50, Santa Cruz Biotechnology, 12732). Samples were rinsed with PBS and incubated with DAPI (1:500 in PBS ...
• Regulating PCCA gene expression by modulation of pseudoexon splicing patterns to rescue enzyme activity in propionic acidemia

  Ulrika Simone Spangsberg Petersen, et al., bioRxiv - Molecular Biology 2023

  Quote: ... or hnRNP A2/B1 (1:1000; sc-53531; Santa Cruz Biotechnology; Santa Cruz, CA), and HPRT1 (1:1000 ...
• Regulating PCCA gene expression by modulation of pseudoexon splicing patterns to rescue enzyme activity in propionic acidemia

  Ulrika Simone Spangsberg Petersen, et al., bioRxiv - Molecular Biology 2023

  Quote: ... or hnRNP A2/B1 (1:1000; sc-53531; Santa Cruz Biotechnology; Santa Cruz, CA), and HPRT1 (1:1000 ...
• Chronic intermittent hypoxia induced-dysmetabolism is associated with hepatic oxidative stress, mitochondrial dysfunction and inflammation

  Joana L. Fernandes, et al., bioRxiv - Physiology 2023

  Quote: ... tumor necrosis factor alfa receptor (TNF-αR) (1:200, Santa Cruz Biotechnology, Madrid, Spain), tumor necrosis factor alfa (TNF-α ...
• Lymphotoxin-β Promotes Bone Colonization and Osteolytic Outgrowth of Indolent Bone Metastatic cells of Breast Cancer

  Xuxiang Wang, et al., bioRxiv - Cell Biology 2023

  Quote: ... α-NFκB p52 (1:1,000 dilution, Santa Cruz Biotechnology, Cat# sc-7386, clone C-5), α-Phospho AKT (1:1,000 dilution ...
• Pre-Injury Mechanoreceptor Ablation Reduces Nociceptor-Driven Spinal Cord Injury-Induced Neuropathic Pain

  Christopher Sliwinski, et al., bioRxiv - Neuroscience 2023

  Quote: ... rabbit anti-protein kinase Cγ (PKCγ [C19], Santa Cruz Biotechnology, SC-211; 1:200), guinea pig anti-NeuN (Millipore ...
• A ubiquitin-proteasome pathway degrades the inner nuclear membrane protein Bqt4 to maintain nuclear membrane homeostasis

  Toan Khanh Le, et al., bioRxiv - Cell Biology 2023

  Quote: ... and an anti-ubiquitin mouse monoclonal antibody (P4D1, 1:1000; Santa Cruz Biotechnology, USA). Protein levels in the input samples were assessed using an anti-β-actin antibody (1:2000 ...