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7551 - 7600 of 8862 citations for 6 1 4 dioxa 8 azaspiro 4.5 decan 8 yl 3 hydroxy 2 iminopyrimidin 4 amine since 2019

• SOCS2 regulation of growth hormone signaling requires a canonical interaction with phosphotyrosine

  Kunlun Li, et al., bioRxiv - Cell Biology 2022

  Quote: ... Anti-actin-HRP antibody (C4) was obtained from Santa Cruz (sc-47778 HRP; 1:1000). Anti-Cullin 5(ab184177) ...
• Cisplatin toxicity is mediated by direct binding to TLR4 through a mechanism that is distinct from metal allergens

  Ivan K. Domingo, et al., bioRxiv - Pharmacology and Toxicology 2022

  Quote: ... Membranes were probed overnight with mouse anti-HA (1:2500) (Santa Cruz, 12CA5 sc-57592) or mouse anti-GAPDH (1:5000 ...
• ISG15 Monomer Promotes IFNα-mediated Antiviral Activity against Pseudorabies Virus by Facilitating phosphorylation of STAT1/STAT2

  Huimin Liu, et al., bioRxiv - Molecular Biology 2022

  Quote: ... Secondary antibodies conjugated with horseradish peroxidase against rabbit or mouse (1:5000 dilution; Santa Cruz) were used ...
• Antagonism between viral infection and innate immunity at the single-cell level

  Frederic Grabowski, et al., bioRxiv - Systems Biology 2022

  Quote: ... anti-RNase L (clone E-9) (catalog number sc-74405; Santa Cruz Biotechnology; 1:1000); anti-OAS1 (clone F-3 ...
• IKKα promotes lung adenocarcinoma growth through activation of ERK signaling via DARPP-32-mediated inhibition of PP1 activity

  Sk. Kayum Alam, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and α-tubulin (cat no. sc-5286; dilution 1:500) were obtained from Santa Cruz Biotechnology ...
• Zinc-finger protein 518 plays a crucial role in pericentromeric heterochromatin formation by linking satellite DNA to heterochromatin

  Shinya Ohta, et al., bioRxiv - Cell Biology 2022

  Quote: Immunoblotting was carried out using mouse anti-MBP (1:200, #sc-271524, Santa Cruz Biotechnology), mouse anti-GST (1:200 ...
• Metabolic control of adaptive β-cell proliferation by the protein deacetylase SIRT2

  Matthew Wortham, et al., bioRxiv - Physiology 2024

  Quote: ... Western blot primary antibodies included: rabbit-anti-Sirt2 (Santa Cruz Biotechnology SC-20966, 1:250), mouse-anti-β-tubulin (Sigma T5201 ...
• AAV-based delivery of RNAi targeting Ataxin-2 improves survival, strength, and pathology in mouse models of rapidly and slowly progressive sporadic ALS

  Defne A. Amado, et al., bioRxiv - Neuroscience 2024

  Quote: ... or anti-Gapdh mouse monoclonal antibody (1:12000; sc-32233; Santa Cruz Biotechnology, Dallas, TX). Membranes were washed x3 with TBS-T for 5 minutes and treated with goat anti-mouse IgG (H+L ...
• XopM, a FFAT motif containing type-III effector protein from Xanthomonas, suppresses PTI responses at the plant plasma membrane

  Charlotte Brinkmann, et al., bioRxiv - Plant Biology 2024

  Quote: ... GFP was detected using a horseradish peroxidase-conjugated anti-GFP antibody (1:1.000; Santa Cruz Biotechnology Inc. ...
• The suprapyramidal and infrapyramidal blades of the dentate gyrus exhibit different GluN subunit content and dissimilar frequency-dependent synaptic plasticity in vivo

  Christina Strauch, et al., bioRxiv - Neuroscience 2024

  Quote: ... or rabbit polyclonal antiNMDAa1 (GluN2A) (1:750; sc-9056, Santa Cruz Biotechnology, Santa Cruz, USA) in tris-buffered saline containing 0.2% Triton X-100 and 1%BSA ...
• Activation of HIF2 leads to vascular remodeling and inflammation, coronary thrombosis and arterial dilation, recapitulating cardiac involvement of Kawasaki disease

  B Escobar, et al., bioRxiv - Pathology 2024

  Quote: ... The primary antibodies used in this study were: anti-PAI-1 (sc-5297, Santa Cruz) 1:500 dilution and anti-vinculin (V4505 ...
• Efficient targeting of heart lesions with cardiac myofibroblasts: Combined gene and cell therapy enhanced by magnetic steering

  M. Schiffer, et al., bioRxiv - Physiology 2024

  Quote: ... slides were incubated with anti-eGFP (1:200 goat polyclonal, Santa Cruz Biotechnology, Delaware, US) after antigen retrieval ...
• Evidence that the monoamine oxidase B (MAO-B) plays a central role in the inotropic dysfunction induced by genetic deletion of the Mas-related-G protein-coupled receptor D (MrgD) in mice

  Lucas Rodrigues-Ribeiro, et al., bioRxiv - Physiology 2024

  Quote: ... Primary antibodies and their sources are as follows: MAO-A (1:1500; Santa Cruz Biotechnology), ATP1A1 (1:100 ...
• Neuronal activation affects the organization and protein composition of the nuclear speckles

  Andrzej Antoni Szczepankiewicz, et al., bioRxiv - Cell Biology 2024

  Quote: ... rabbit anti-PSF (H-80) polyclonal IgG (1:20, Santa Cruz Biotechnology Inc., sc-28730), rabbit anti-Sam68 polyclonal IgG (C-20 ...
• The suprapyramidal and infrapyramidal blades of the dentate gyrus exhibit different GluN subunit content and dissimilar frequency-dependent synaptic plasticity in vivo

  Christina Strauch, et al., bioRxiv - Neuroscience 2024

  Quote: ... or rabbit polyclonal antiNMDAa1 (GluN2A) (1:750; sc-9056, Santa Cruz Biotechnology, Santa Cruz, USA) in tris-buffered saline containing 0.2% Triton X-100 and 1%BSA ...
• The expression of PKM1 and PKM2 in developing, benign, and cancerous prostatic tissues

  Lin Li, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Primary antibodies are beta-actin (sc-47778, dilution 1:500, Santa Cruz Biotechnology, Dallas, TX), PKM1 and PKM2 (the same source as mentioned above ...
• Neuronal activation affects the organization and protein composition of the nuclear speckles

  Andrzej Antoni Szczepankiewicz, et al., bioRxiv - Cell Biology 2024

  Quote: ... rabbit polyclonal IgG anti-coilin (H-300) (1:20, Santa Cruz Biotechnology Inc., sc-32860), rabbit anti-PSF (H-80 ...
• A multiprotein signaling complex sustains AKT and mTOR/S6K activity necessary for the survival of cancer cells undergoing stress

  Oriana Y. Teran Pumar, et al., bioRxiv - Cancer Biology 2024

  Quote: ... samples were incubated in primary antibodies for Dock7 (1:200; Santa Cruz Biotechnology, sc-398888) and LAMP1 (1:200 ...
• Spatiotemporal recruitment of the ubiquitin-specific protease USP8 directs endosome maturation

  Yue Miao, et al., bioRxiv - Cell Biology 2024

  Quote: ... The primary antibodies used in this study were: USP8 (sc-376130, 1:500, Santa Cruz), GFP (14-6674-82 ...
• Interactors of sacsin’s DNAJ domain identify function in organellar transport and membrane composition relevant to ARSACS pathogenesis

  Alexandre M. Paré, et al., bioRxiv - Cell Biology 2024

  Quote: ... rabbit polyclonal anti-ARF5 (clone 9E10, Santa Cruz Biotechnology, Santa Cruz, CA, USA, 1:400), rabbit polyclonal anti-ATG9A (26276-1-AP ...
• Mucin MUC5B levels are reduced in the colonic epithelia of ulcerative colitis patients

  Wei Ding, Walter A. Koltun, Gregory S. Yochum, bioRxiv - Cell Biology 2024

  Quote: ... The slides were incubated with anti-MUC2 antibodies (1:500, Santa Cruz, Ccp58, sc-7314) or anti-MUC5B antibodies (1:200 ...
• Pneumocystis murina Promotes Inflammasome Formation and NETosis during Pneumocystis Pneumonia

  Steven G. Sayson, et al., bioRxiv - Immunology 2024

  Quote: ... then incubated with anti-Neutrophil Elastase-AlexaFluor 488 (1:100; Santa Cruz Biotechnology, Dallas, TX), anti-Citrullinated Histone H3 (1:100 ...
• The inflammatory microenvironment of the lung at the time of infection governs innate control of SARS-CoV-2 replication

  Paul J. Baker, et al., bioRxiv - Immunology 2024

  Quote: ... and actin was detected using mouse-α-actin-HRP (Santa Cruz, #sc-47778, 1:5000).
• Identification of neuronal ensembles involved in remote fear memory extinction impairments

  Kamil F. Tomaszewski, et al., bioRxiv - Animal Behavior and Cognition 2023

  Quote: ... sections were incubated with c-Fos polyclonal antibody (sc-52; Santa Cruz Biotechnology, 1:1000) for 12h in 37℃ ...
• Cortical neurons obtained from patient-derived iPSCs with GNAO1 p.G203R variant show altered differentiation and functional properties

  Maria Cristina Benedetti, et al., bioRxiv - Neuroscience 2023

  Quote: ... and anti-GAPDH (6C5) mouse monoclonal antibody (1:500, cat# sc-32233, Santa Cruz Biotechnologies) in T-TBS with 5% BSA ...
• Oncogenic Mutant p53 Sensitizes Non-Small Cell Lung Cancer Cells to Proteasome Inhibition via Oxidative Stress-Dependent Induction of Mitochondrial Apoptosis

  Kranthi Kumar Chougoni, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Primary antibodies were used in a 1:100 dilution for NRF2 (Santa Cruz, sc-13032). Secondary antibodies were used in a 1:300 dilution for mouse anti-rabbit IgG-CFL 594 (Santa Cruz ...
• Opposing actions of JIP4 and RILPL1 provide antagonistic motor force to dynamically regulate membrane reformation during lysosomal tubulation/sorting driven by LRRK2

  Luis Bonet-Ponce, et al., bioRxiv - Cell Biology 2024

  Quote: ... and rabbit anti-Tom20 (FL-145) (Santa Cruz Biotechnology, sc-11415; 1:5000 for WB).
• The pregnancy-associated protein glycodelin as a potential sex-specific target for resistance to immunotherapy in non-small cell lung cancer

  Sarah Richtmann, et al., bioRxiv - Cancer Biology 2023

  Quote: ... The following antibodies were used: glycodelin 1:1000 (N-20, Santa Cruz Biotechnology, Dallas, TX), CD68 1:100 (PG-M1 ...
• Self-stabilization mechanism encoded by a bacterial toxin facilitates reproductive parasitism

  Toshiyuki Harumoto, bioRxiv - Microbiology 2023

  Quote: The following antibodies were used: mouse anti-Ubiquitin P4D1 (1/1,000; Santa Cruz, sc-8017); rabbit anti-GFP (1/10,000 ...
• The FSGS disease gene product and nuclear pore protein NUP205 regulates nuclear localization and activity of the transcriptional regulators YAP and TAZ in podocytes

  Lioba Ester, et al., bioRxiv - Cell Biology 2023

  Quote: ... whole cell supernatants were incubated with 1 µg of rabbit IgG (Santa Cruz, sc-2027) or 0.2 µg of rabbit anti-YAP (Cell Signaling ...
• Cx26 heterozygous mutations cause hyperacusis-like hearing sensitivity enhancement and increase susceptibility to noise

  Li-Man Liu, et al., bioRxiv - Neuroscience 2022

  Quote: ... or polyclonal goat anti-prestin (1:50, Cat# sc-22694, Santa Cruz Biotech Inc. CA) were used ...
• Development of a fluorescence reporter system to quantify transcriptional activity of endogenous p53 in living cells

  Tatsuki Tsuruoka, et al., bioRxiv - Cell Biology 2022

  Quote: ... The first antibody was mouse monoclonal anti-p53/DO-1 (SC-126) (Santa Cruz Biotechnology) for determination of the p53 expression level and mouse monoclonal anti-p53(Ser15)/16G8 (9286 ...
• Design of a Streptococcus pyogenes M protein immunogen to elicit M type cross-reactivity

  Kuei-Chen Wang, et al., bioRxiv - Immunology 2023

  Quote: ... followed by incubation for 1 h with goat anti-chicken IgY-HRP (Santa Cruz Biotechnology) at 1:2500 dilution in 0.1% BSA/TBST.
• Defective engram allocation contributes to impaired fear memory performance in Down syndrome

  Álvaro Fernández-Blanco, et al., bioRxiv - Neuroscience 2023

  Quote: ... Arc was stained with mouse anti-Arc(C-7) (1:400; Santa Cruz, #sc-17839) and visualized with anti-mouse Alexa-488 (1:500 ...
• DNMT3A clonal hematopoiesis-driver mutations induce cardiac fibrosis by paracrine activation of fibroblasts

  Mariana Shumliakivska, et al., bioRxiv - Physiology 2023

  Quote: ... Membranes were blocked for 1 h in 5 % Blotto nonfat milk (#sc-2325, Santa Cruz), dissolved in Tris-buffered saline supplemented with Tween-20 (1x TBST ...
• Functional diversity of the TP53 mutome revealed by saturating CRISPR mutagenesis

  Julianne Funk, et al., bioRxiv - Cancer Biology 2023

  Quote: ... antigens were detected using the antibodies: p53 (Santa Cruz Biotechnology, sc-126; antibody DO-1), p21 (Santa Cruz Biotechnology ...
• The SOCS1 KIR and SH2 domain are both required for suppression of cytokine signaling in vivo

  Karen Doggett, et al., bioRxiv - Cell Biology 2022

  Quote: ... Anti-actin-HRP antibody (C4) was obtained from Santa Cruz (sc-47778 HRP; 1:1000). Antibody binding was visualized with peroxidase-conjugated sheep anti-rabbit immunoglobulin (Southern Biotech ...
• Pseudouridine prevalence in Kaposi’s sarcoma-associated herpesvirus transcriptome reveals an essential mechanism for viral replication

  Timothy J. Mottram, et al., bioRxiv - Microbiology 2023

  Quote: ... The antibodies used throughout this study include anti-ORF57 (Santa Cruz, sc-135746 1:1,000), anti-ORF65 ...
• Long lifetime and selective accumulation of the A-type lamins accounts for the tissue specificity of Hutchinson-Gilford progeria syndrome

  John Hasper, et al., bioRxiv - Cell Biology 2023

  Quote: ... and Progerin: Lamin A/C E-1 (Santa Cruz sc-376248, 20 uL per IP) and Lamin A/C (Active Motif #39288 Clone 3A6-4C11 ...
• Chromatin organization drives the exploration strategy of nuclear factors

  Matteo Mazzocca, et al., bioRxiv - Biophysics 2023

  Quote: ... The antibodies employed in this study were: mouse monoclonal anti-p53 DO-1 (Santa Cruz Biotechnology ...
• Asymmetric cell division-specific phosphorylation of PAR-3 regulates neuroblasts polarisation and sensory organ formation in Drosophila

  Nicolas Loyer, et al., bioRxiv - Developmental Biology 2023

  Quote: ... Primary antibodies used were as follows: rabbit anti-PKCζ (Santa Cruz, sc-17781, 1:500); Sheep-anti-Mira (1:1000) ...
• Virally induced lipid droplets are a platform for innate immune signalling complexes

  EA Monson, et al., bioRxiv - Immunology 2023

  Quote: ... The primary antibodies used were: mouse monoclonal αCalnexin (1:1000; sc-23954, Santa Cruz Biotechnology), mouse monoclonal αmfn1 (1:1000 ...
• β-actin is essential for structural integrity and physiological function of the retina

  Pavan Vedula, et al., bioRxiv - Cell Biology 2023

  Quote: ... rat anti-HCAM (CD44) (1:10 dilution, clone IM7, sc-18849, Santa Cruz Biotechnology Inc.), rabbit anti-Gβ1 (1:100 dilution ...
• Arl3 regulates ODA16-mediated intraflagellar transport in motile cilia biogenesis

  Yameng Huang, et al., bioRxiv - Cell Biology 2023

  Quote: The following antibodies were commercially available: anti-HA (mouse, Santa Cruz, sc-7392, 1:500), anti-HA (mouse ...
• ATRX guards against aberrant differentiation in mesenchymal progenitor cells

  Yan Fang, et al., bioRxiv - Genetics 2023

  Quote: ... Antibodies used for Western blot are the following: ATRX (Santa Cruz, sc-15408, 1:800), FABP4 (R&D ...
• Spastin locally amplifies microtubule dynamics to pattern the axon for presynaptic cargo delivery

  Jayne Aiken, Erika L. F. Holzbaur, bioRxiv - Cell Biology 2023

  Quote: ... Membranes were incubated with spastin primary antibody (Sp 3G11/1; Santa Cruz Biotechnology; sc-53443) diluted 1:200 in EveryBlot at 4C overnight ...
• Emotional association enhances perceptual memory through amygdalo-cortical inputs during NREM sleep

  Yoshihito Saito, et al., bioRxiv - Neuroscience 2023

  Quote: ... We used an anti-c-Fos antibody (rabbit, 1/1000, #SC-52, Santa Cruz Biotechnology) as the primary antibody and anti-rabbit IgG antibody conjugated with Alexa Fluor 488 (goat ...
• Expression and purification of the mitochondrial transmembrane protein FAM210A in Escherichia coli

  Jared Hollinger, et al., bioRxiv - Biochemistry 2023

  Quote: ... Mouse monoclonal anti-EF-Tu antibody (sc-393924; 1:500) was purchased from Santa Cruz. The secondary antibodies used in the present study included ECL rabbit IgG ...
• COGNITIVE REJUVENATION IN OLD RATS BY HIPPOCAMPAL OSKM GENE THERAPY

  Steve Horvath, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-doublecortin (DCX) goat polyclonal antibody 1:250 (c-18, Santa Cruz Biotech., Dallas, Texas), mouse anti-hOct4 (1:10 ...
• Elucidation of antiviral mechanisms of natural therapeutic molecules Herbacetin and Caffeic acid phenethyl ester against chikungunya and dengue virus

  Mandar Bhutkar, et al., bioRxiv - Microbiology 2023

  Quote: ... cells were incubated with antibodies against CHIKV and DENV (anti-alphavirus 1:100, SANTA Cruz Biotechnology Inc ...