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• Development of Gemcitabine-Modified miRNA Mimics as Cancer Therapeutics for Pancreatic Ductal Adenocarcinoma

  John G. Yuen, et al., bioRxiv - Cancer Biology 2023

  Quote: ... or mouse anti-GAPDH antibody (Santa Cruz, sc47724, 1:100,000). Primary antibodies were diluted in 5% milk (Bio-Rad ...
• Targeting CD19-positive lymphomas with the antibody-drug conjugate (ADC) loncastuximab tesirine: preclinical evidence as single agent and as combinatorial approach

  Chiara Tarantelli, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and 4-hydroperoxy-cyclophosphamide from Santa Cruz Biotechnology (Heidelberg ...
• Increased beta2-adrenergic signaling is a targetable stimulus essential for bone healing by promoting callus neovascularization

  Denise Jahn, et al., bioRxiv - Cell Biology 2023

  Quote: ... The primary antibodies (anti-Cd31, goat polyclonal, R&D Systems #AF3628, 1:100; anti-VEGFA, rabbit monoclonal, abcam #ab52917, 1:200; anti-Endomucin, rat, Santa Cruz #sc-65495, 1:100 in AK Diluent) and secondary antibodies (anti-goat 546 ...
• CCR9 overexpression promotes T-ALL progression by enhancing cholesterol biosynthesis

  Muhammad Jamal, et al., bioRxiv - Cancer Biology 2023

  Quote: ... 5×105 target cells were incubated with lentiviral supernatant containing polybrene (8 µg/mL) (Santa Cruz, Germany). Cells were subsequently centrifuged at 2000 rpm for 90 min ...
• The microglia receptor protein TREM2 is essential for protective innate immune responses against herpesvirus infection in the brain

  Stefanie Fruhwürth, et al., bioRxiv - Immunology 2023

  Quote: ... and the detector antibody was monoclonal mouse anti-human TREM2 (1 μg/mL, Santa Cruz Biotechnology). A standard curve for calculations of unknowns was constructed using recombinant human TREM2 (4000–62.5 pg/mL ...
• Simultaneous targeting of AMPK and mTOR is a novel therapeutic strategy against prostate cancer

  Gangyin Zhao, et al., bioRxiv - Cancer Biology 2023

  Quote: ... AMPK (Santa Cruz Bio: sc-74461), mTOR (Santa Cruz Bio ...
• Exploiting Epigenetic Targets to Overcome Taxane Resistance in Prostate Cancer

  Buse Cevatemre, et al., bioRxiv - Cancer Biology 2023

  Quote: ... stained with 0.4% (w/v) SRB (Santa Cruz, sc-253615) for 30 min and subsequently washed with 1% acetic acid ...
• Partitioning heritability using single-cell multi-omics identifies a novel macrophage subpopulation conveying genetic risks of coronary artery disease

  Jiahao Jiang, et al., bioRxiv - Genetics 2023

  Quote: ... Nuclei were counterstained with Hoechst 33342 (Santa Cruz Biotechnology) diluted 1:10,000 in PBS ...
• Near chromosome-level and highly repetitive genome assembly of the snake pipefish Entelurus aequoreus (Syngnathiformes: Syngnathidae)

  Magnus Wolf, et al., bioRxiv - Genomics 2023

  Quote: ... A proximity-ligation library was compiled with muscle tissue following the Dovetail™ Omni-C protocol (Dovetail Genomics, Santa Cruz, California, USA). In addition ...
• Ulk4 promotes Shh signaling by regulating Stk36 ciliary localization and Gli2 phosphorylation

  Mengmeng Zhou, Yunong Han, Jin Jiang, bioRxiv - Developmental Biology 2023

  Quote: ... Antibodies used in this study were as follows: Mouse anti-Myc (Santa Cruz Biotechnology; 9E10), Mouse anti-Flag (Sigma ...
• The nuclear import receptor Kapβ2 modifies neurotoxicity mediated by poly(GR) in C9orf72-linked ALS/FTD

  ME Cicardi, et al., bioRxiv - Neuroscience 2023

  Quote: Primary antibodies: anti-Kapβ2 (RRID:AB_2206884, Santa Cruz Biotechnology ...
• Atrial t-tubules adopt a specialist developmental state while alterations to Ca²⁺ buffering maintain systolic Ca²⁺ during postnatal development

  CER Smith, et al., bioRxiv - Physiology 2023

  Quote: ... anti-goat and anti-rabbit secondary antibodies (1:40,000, Santa Cruz Biotechnology). Chemiluminescence substrate (GE Healthcare ...
• Atrial t-tubules adopt a specialist developmental state while alterations to Ca²⁺ buffering maintain systolic Ca²⁺ during postnatal development

  CER Smith, et al., bioRxiv - Physiology 2023

  Quote: ... Membranes were incubated with primary antibodies targeted to AMPII (1:200, Santa Cruz Biotechnology), JPH2 (1:5000 ...
• Identifying cellular RNA-binding proteins during infection uncovers a role for MKRN2 in influenza mRNA trafficking

  Stefano Bonazza, et al., bioRxiv - Microbiology 2023

  Quote: ... NS1 (Santa Cruz; Sc-13056), YTHDF2 (Proteintech ...
• Aberrant pace of cortical neuron development in brain organoids from patients with 22q11.2 deletion syndrome and schizophrenia

  Sneha B. Rao, et al., bioRxiv - Neuroscience 2023

  Quote: ... and immature neuron marker DCX (mouse anti-DCX, Santa Cruz Biotech sc-271390, 1:250) to assess cell development and neurite specification.
• Genetic and pharmacologic alterations of claudin9 levels suffice to induce functional and mature inner hair cells

  Yingying Chen, et al., bioRxiv - Neuroscience 2023

  Quote: ... mouse anti-Cldn9 (Santa Cruz, 1:200, Cat # sc-398836), (7 ...
• Genetic and pharmacologic alterations of claudin9 levels suffice to induce functional and mature inner hair cells

  Yingying Chen, et al., bioRxiv - Neuroscience 2023

  Quote: ... rabbit anti-Prestin (Santa Cruz, 1:200, Cat # sc-22692), and (13 ...
• De-suppression of mesenchymal cell identities and variable phenotypic outcomes associated with knockout of Bbs1

  Grace Freke, et al., bioRxiv - Genetics 2023

  Quote: Mouse antibody against PCM-1 (sc-398365) was purchased from Santa Cruz Biotechnology ...
• Oligodendroglial precursors orchestrate immune network instigating early demyelination in experimental autoimmune encephalomyelitis

  Qi Wang, et al., bioRxiv - Neuroscience 2023

  Quote: ... Mouse anti-IP3R2 (Santa Cruz, SC393434), Goat anti-Iba1 (Wako ...
• No evidence that post-training D2R dopaminergic drug administration affects fear generalization in male rats

  Natalie Schroyens, et al., bioRxiv - Neuroscience 2023

  Quote: ... raclopride HCl (RACLO; 0.3 mg/kg; Santa Cruz Biotechnology), or saline was administered immediately after conditioning ...
• CelltypeR: A flow cytometry pipeline to annotate, characterize and isolate single cells from brain organoids

  Rhalena A. Thomas, et al., bioRxiv - Neuroscience 2023

  Quote: ... SSEA-4 (1:200, Santa Cruz Biotechnology sc-21704); in blocking buffer overnight at 4 °C ...
• Tropism of AAV.CPP.16 in the respiratory tract and its application for a CRISPR-based gene therapy against SARS-CoV-2

  Zhi Yang, et al., bioRxiv - Bioengineering 2023

  Quote: ... mouse anti-CC10 (1:400, sc-390313, Santa Cruz), rabbit anti-CC10 (1:200 ...
• Acetylation of WCC is dispensable for the core circadian clock but differentially regulates acute light responses in Neurospora

  Bin Wang, et al., bioRxiv - Biochemistry 2023

  Quote: ... and Ac-lysine Antibody (AKL5C1) (Santa Cruz Biotechnology, Catalog # sc-32268), each of which was employed in Western blotting at a dilution of 1:1,000.
• p53 rapidly restructures 3D chromatin organization to trigger a transcriptional response

  François Serra, et al., bioRxiv - Genomics 2023

  Quote: ... The following primary antibodies were used: p53 DO1 (Santa Cruz Biotechnology, sc-126, diluted 1:200), RAD21 (Abcam ...
• Autologous iPSC- and MSC-derived Chondrocyte Implants for Cartilage Repair in a Miniature Pig Model

  Ming-Song Lee, et al., bioRxiv - Bioengineering 2023

  Quote: ... and COL10A1 (Santa Cruz Biotechnology) at a 1:200 ratio for 1 hour at 4°C ...
• Autologous iPSC- and MSC-derived Chondrocyte Implants for Cartilage Repair in a Miniature Pig Model

  Ming-Song Lee, et al., bioRxiv - Bioengineering 2023

  Quote: ... COL2A1 (Santa Cruz Biotechnology), and COL10A1 (Santa Cruz Biotechnology ...
• A developmentally-inspired hypoxia condition promotes kidney organoid differentiation from human pluripotent stem cells

  Hyeonji Lim, et al., bioRxiv - Bioengineering 2023

  Quote: ... and anti-goat (1:5000) (sc-2020, Santa Cruz Biotechnology) antibodies ...
• Multi-omics analyses identify transcription factor interplay in corneal epithelial fate determination and disease

  Jos GA Smits, et al., bioRxiv - Developmental Biology 2023

  Quote: ... p63 (Santa Cruz #H129 ...
• Inhibition of Type I PRMTs Reforms Muscle Stem Cell Identity Enhancing their Therapeutic Capacity

  Claudia Dominici, et al., bioRxiv - Molecular Biology 2023

  Quote: ... MyoD (Santa Cruz Biotechnology, 1:200), ki67 (Abcam ...
• Sex differences in anxiety and threat avoidance in GAD65 knock-out mice

  Michelle Ulrich, et al., bioRxiv - Neuroscience 2023

  Quote: ... Free-floating sections were either incubated with a rabbit monoclonal anti-SST antibody (1:250, Santa Cruz Biotechnology #sc13099 ...
• Chemotherapeutic regulation of the ROS/MondoA-dependent TXNIP/GDF15 axis; and derivation of a new organoid metric as a predictive biomarker

  Jinhai Deng, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Cas9 (1:1000, Santa Cruz), GDF15 (1:1000 ...
• AMPK targets PDZD8 to trigger carbon source shift to glutamine

  Mengqi Li, et al., bioRxiv - Cell Biology 2023

  Quote: ... 1:500 for IP or 1:120 for IF) antibodies were purchased from Santa Cruz Biotechnology ...
• The CUL4-DDB1-DCAF1 E3 ubiquitin ligase complex regulates PLK4 protein levels to prevent premature centriole duplication

  Josina Grossmann, et al., bioRxiv - Cell Biology 2023

  Quote: ... cell extracts were incubated with 4 μg of mouse anti-DCAF1 (Santa Cruz Biotechnology, catalog no.: sc-376850) antibody overnight on a rotating wheel ...
• The CUL4-DDB1-DCAF1 E3 ubiquitin ligase complex regulates PLK4 protein levels to prevent premature centriole duplication

  Josina Grossmann, et al., bioRxiv - Cell Biology 2023

  Quote: ... α-rootletin (C-2, catalog no.: sc-374056) antibody was purchased from Santa Cruz Biotechnology ...
• Integration of Patient-Derived Organoids and Organ-on-Chip Systems: Investigating Colorectal Cancer Invasion within the Mechanical and GABAergic Tumor Microenvironment

  Carly Strelez, et al., bioRxiv - Cancer Biology 2023

  Quote: ... The primary antibodies used for the HCT116 H2B-GFP ABAT knock down validation were mouse anti-ABAT (1:500; Santa Cruz Technology, Inc., #sc-393769) and mouse anti-Actin (1:10000 ...
• Integration of Patient-Derived Organoids and Organ-on-Chip Systems: Investigating Colorectal Cancer Invasion within the Mechanical and GABAergic Tumor Microenvironment

  Carly Strelez, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and 2 mg/mL of puromycin (Santa Cruz Biotechnology, #sc-108071) was used to select for knocked down cells ...
• A mitochondria-regulated p53-CCF circuit integrates genome integrity with inflammation

  Karl N. Miller, et al., bioRxiv - Cell Biology 2023

  Quote: ... p53 (Santa Cruz Biotechnology Cat#sc-126 ...
• S100A8/A9 predicts triple-negative breast cancer response to PIM kinase and PD-1/PD-L1 inhibition

  Lauren R. Begg, et al., bioRxiv - Cancer Biology 2023

  Quote: The antibodies used for western blotting in this study are: βActin (clone C4, Santa Cruz Biotechnology, sc-47778 HRP), human PIM1 (clone ZP003 ...
• MET variants with activating N-lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

  Célia Guérin, et al., bioRxiv - Cancer Biology 2023

  Quote: ... ERK1/2 (Santa Cruz #Sc-154), ERK1/2-Phospho (Cell Signaling #9101) ...
• Methylation of histone H3 lysine 36 is a barrier for therapeutic interventions of head and neck squamous cell carcinoma

  Lucas D. Caeiro, et al., bioRxiv - Cancer Biology 2023

  Quote: ... BRCA1 (Santa Cruz), RAD51 (B-Bridge International) ...
• GRAMD2⁺ alveolar type I cell plasticity facilitates cell state transitions in organoid culture

  Hua Shen, et al., bioRxiv - Cell Biology 2023

  Quote: ... SCGB1A1 (1:500, #S9772, Santa Cruz), SCGB3A2 (1:200 ...
• Cortical network and projection neuron types that articulate serial order in a skilled motor behavior

  Yi Li, et al., bioRxiv - Neuroscience 2023

  Quote: ... or mouse anti-Tle4 antibody (1:500, Cat#sc-365406, Santa Cruz Biotechnology). Briefly ...
• The E3 ubiquitin ligase RNF220 maintains hindbrain Hox expression patterns through regulation of WDR5 stability

  Huishan Wang, et al., bioRxiv - Developmental Biology 2023

  Quote: ... anti-CBX7 (G-3) (Santa Cruz; sc-376274), anti-CBX8 (C-3 ...
• Functional diversity of NLRP3 gain-of-function mutants associated with CAPS autoinflammation

  Camille Cosson, et al., bioRxiv - Immunology 2023

  Quote: ... anti-LaminB (B-10, Santa Cruz Biotechnology), anti-actin (C4 ...
• NK and NKT cells in the pathogenesis of Hidradenitis suppurativa: Novel therapeutic strategy through targeting of CD2

  Mahendra P. Kashyap, et al., bioRxiv - Immunology 2023

  Quote: ... the tissues were homogenized using cold RIPA buffer (Santa Cruz biotechnologies) containing 2 mM sodium orthovanadate ...
• The nuclear PIWI-interacting protein Gtsf1 controls the selective degradation of small RNAs in Paramecium

  Olivia Charmant, et al., bioRxiv - Genetics 2023

  Quote: ... α-tubulin (1:5,000) (sc-8035, Santa Cruz) or TEU435 (1:4,000)(Callen et al. ...
• Metallo-protease Peptidase M84 from Bacillus altitudinis induces ROS dependent apoptosis in ovarian cancer cells by targeting PAR-1

  Niraj Nag, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-phospho-p38 antibody (Santa Cruz Biotechnology Cat# sc-166182) and anti-p50 antibody (Santa Cruz Biotechnology Cat# sc-8414 ...
• Phosphatidylserine clustering by membrane receptors triggers LC3-associated phagocytosis.

  Emilio Boada-Romero, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-NAPDH oxidase 2 (anti-NOX2/gp91-phox; Santa Cruz Technology, sc-130543), anti-Rubicon (Clone D9F7 ...
• Revisiting the trafficking of insulin and its receptor in rat liver: in vivo and cell-free studies

  Khadija Tahiri, et al., bioRxiv - Cell Biology 2023

  Quote: ... Antibodies against the β subunit of the insulin receptor were from Santa Cruz Biotechnology ...
• Phagocytosis in macrophages is regulated by the ATP-binding cassette family gene ABCF1

  Hitesh Arora, et al., bioRxiv - Immunology 2023

  Quote: ... siRNAs from Santa Cruz Biotechnology (catalog numbers sc-29851 and sc-106845 ...